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About biofilm – University of Copenhagen

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About Biofilm

In nature bacteria often appear as sessile, matrix embedded aggregates commonly referred to as biofilms. There is accumulating evidence that in case bacteria succeed in forming biofilms within the host, the infection develops into a chronic state. The important hallmarks are development of inflammations, host tissue degradation, extreme tolerance to the action of conventional antimicrobial agents and an almost infinite capacity to evade the host defense systems. With an apparent similarity to cancers, biofilms can proliferate into a dispersal mode, spread cells and spark new areas of biofilm infections.

Biofilms on indwelling medical devices

Due to advances in medical technology and an ageing population, there is an increasing problem with medical device-associated infections.

Integrating medical-, oral-, and environmental- microbiology with development of biofilm controlling chemical agents will pave the way for a solution to combat the problem of biofilm induced infections.


  • Dental plaque
  • Coronary implants
  • Venous catheter
  • Hip implant
  • Urinary catheter