Michael Givskov

Michael Givskov

Professor

Member of:


    1. 2017
    2. Published

      A Linker for the Solid-Phase Synthesis of Hydroxamic Acids and Identification of HDAC6 Inhibitors

      Bang, C. G., Jensen, J. F., O'Hanlon Cohrt, E., Olsen, L. B., Siyum, S. G., Mortensen, K. T., Skovgaard, T., Berthelsen, J., Yang, L., Givskov, Michael, Qvortrup, K. & Nielsen, T. E., Oct 2017, In: ACS Combinatorial Science. 19, 10, p. 657-669 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    3. Published

      Reduced intracellular c-di-GMP content increases expression of quorum sensing-regulated genes in Pseudomonas aeruginosa

      Chua, S. L., Liu, Y., Li, Y., Ting, H. J., Kohli, G. S., Cai, Z., Suwanchaikasem, P., Goh, K. K. K., Ng, S. P., Tolker-Nielsen, Tim, Yang, L. & Givskov, Michael, Oct 2017, In: Frontiers in Cellular and Infection Microbiology. 7, 8 p., 451.

      Research output: Contribution to journalJournal articlepeer-review

    4. Published

      Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes

      Jakobsen, Tim Holm, Tolker-Nielsen, Tim & Givskov, Michael, Sep 2017, In: International Journal of Molecular Sciences. 18, 9, 27 p., 1970.

      Research output: Contribution to journalReviewpeer-review

    5. Published

      Cholesterol crystals enhance TLR2-and TLR4-mediated pro-inflammatory cytokine responses of monocytes to the proatherogenic oral bacterium Porphyromonas gingivalis

      Køllgaard, T. M. S., Enevold, Christian, Bendtzen, K., Hansen, Peter Riis, Givskov, Michael, Holmstrup, Palle & Nielsen, Claus Henrik, 24 Feb 2017, In: P L o S One. 12, 2, 14 p., 0172773.

      Research output: Contribution to journalJournal articlepeer-review

    6. Published

      Disulfide Bond-Containing Ajoene Analogues As Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa

      Fong, J., Yuan, M., Jakobsen, Tim Holm, Mortensen, K. T., Delos Santos, M. M. S., Chua, S. L., Yang, L., Tan, C. H., Nielsen, T. E. & Givskov, Michael, 12 Jan 2017, In: Journal of Medicinal Chemistry. 60, 1, p. 215-227

      Research output: Contribution to journalJournal articlepeer-review

    7. Published

      Gauging and visualizing c-di-GMP levels in pseudomonas aeruginosa using fluorescence-based biosensors

      Rybtke, Morten Levin, Chua, S. L., Yam, J. K. H., Givskov, Michael, Yang, L. & Tolker-Nielsen, Tim, Jan 2017, c-di-GMP Signaling: Methods and Protocols. Sauer, K. (ed.). Humana Press, Vol. 1657. p. 87-98 12 p. (Methods in Molecular Biology, Vol. 1657).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    8. Published

      High-throughput screening for compounds that modulate the cellular c-di-GMP level in bacteria

      Groizeleau, J., Andersen, Jens Bo, Givskov, Michael, Berthelsen, J. & Tolker-Nielsen, Tim, Jan 2017, c-di-GMP Signaling: Methods and Protocols. Sauer, K. (ed.). Humana Press, Vol. 1657. p. 455-470 16 p. (Methods in Molecular Biology, Vol. 1657).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    9. Published

      A broad range quorum sensing inhibitor working through sRNA inhibition

      Jakobsen, Tim Holm, Warming, A. N., Vejborg, R. M., Moscoso, J. A., Stegger, M., Lorenzen, F., Rybtke, Morten Levin, Andersen, Jens Bo, Petersen, R., Andersen, P. S., Nielsen, T. E., Tolker-Nielsen, Tim, Filloux, A., Ingmer, Hanne & Givskov, Michael, 2017, In: Scientific Reports. 7, 1, 12 p., 9857.

      Research output: Contribution to journalJournal articlepeer-review

    10. Published

      Cyclic-di-GMP is required for corneal infection by Pseudomonas aeruginosa and modulates host immunity

      Hoong Yam, J. K., Aung, T. T., Chua, S. L., Cheng, Y., Kohli, G. S., Zhou, J., Constancias, F., Liu, Y., Cai, Z., Santillan Salido, M. M., Drautz-Moses, D. I., Rice, S. A., Schuster, S. C., Wu, B., Kjelleberg, S., Tolker-Nielsen, Tim, Beuerman, R. W., Givskov, Michael & Yang, L., 2017, bioRxiv, 35 p.

      Research output: Working paperPreprintResearch

    11. Discovery of novel antimycobacterial drug therapy in biofilm of pathogenic nontuberculous mycobacterial keratitis

      Aung, T. T., Chor, W. H. J., Yam, J. K. H., Givskov, Michael, Yang, L. & Beuerman, R. W., 2017, In: Ocular Surface. 15, 4, p. 770-783 14 p.

      Research output: Contribution to journalJournal articlepeer-review

    12. Published

      Fusaric acid and analogues as gram-negative bacterial quorum sensing inhibitors

      Thanh Tung, T., Jakobsen, Tim Holm, Dao, T. T., Fuglsang, Anja Thoe, Givskov, Michael, Christensen, Søren Brøgger & Nielsen, J., 2017, In: European Journal of Medicinal Chemistry. 126, p. 1011-1020 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    13. Published

      In Vitro Evaluation of Biofilm Dispersal as a Therapeutic Strategy To Restore Antimicrobial Efficacy

      Roizman, D., Vidaillac, C., Givskov, Michael & Yang, L., 2017, In: Antimicrobial Agents and Chemotherapy. 61, 10, 5 p., e01088-17.

      Research output: Contribution to journalJournal articlepeer-review

    14. Published

      In vitro and In vivo efficacy of an LpxC inhibitor, CHIR-090, alone or combined with colistin against Pseudomonas aeruginosa biofilm

      Tan, J. H., Vidaillac, C., Yam, J. K. H., Chua, S. L., Givskov, Michael & Yang, L., 2017, In: Antimicrobial Agents and Chemotherapy. 61, 7, 9 p., e02223-16.

      Research output: Contribution to journalJournal articlepeer-review

    15. Published

      Kinase Inhibitors

      Wu, P., Givskov, Michael & Nielsen, T. E., 2017, Drug Selectivity: An Evolving Concept in Medicinal Chemistry. Wiley-Interscience, p. 33-53 21 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    16. Published

      Metagenomic and metatranscriptomic analysis of saliva reveals disease-associated microbiota in patients with periodontitis and dental caries

      Midjord-Belstrøm, Daniel, Constancias, F., Liu, Y., Yang, L., Drautz-Moses, D. I., Schuster, S. C., Kohli, G. S., Jakobsen, Tim Holm, Holmstrup, Palle & Givskov, Michael, 2017, In: npj Biofilms and Microbiomes. 3, 8 p., 23.

      Research output: Contribution to journalJournal articlepeer-review

    17. Published

      Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB

      Fazli, M., Rybtke, Morten Levin, Steiner, E., Weidel, E., Berthelsen, J., Groizeleau, J. D. D., Bin, W., Zhi, B. Z., Yaming, Z., Kaever, V., Givskov, Michael, Hartmann, R. W., Eberl, L. & Tolker-Nielsen, Tim, 2017, In: MicrobiologyOpen. 6, 4, 13 p., e00480.

      Research output: Contribution to journalJournal articlepeer-review

    18. Published

      Synergy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Inhibiting P.aeruginosa Quorum Sensing

      Fong, J., Zhang, C., Yang, R., Boo, Z. Z., Tan, S. K., Nielsen, T. E., Givskov, Michael, Wu, B., Su, H. & Yang, L., 2017, bioRxiv, 27 p.

      Research output: Working paperPreprintResearch

    19. Published

      The Acquisition of Resistance to Carbapenem and Macrolide-mediated Quorum Sensing Inhibition by Pseudomonas aeruginosa via a Novel Integrative and Conjugative Element ICETn43716385

      Ding, Y., Teo, J., Drautz-Moses, D. I., Schuster, S. C., Givskov, Michael & Yang, L., 2017, bioRxiv, 95 p.

      Research output: Working paperPreprintResearch

    ID: 5838523