Niels Høiby

Niels Høiby

Professor, No job title

Member of:

    ORCID: 0000-0002-1347-725X

    Publication year:
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    1 - 50 out of 507Page size: 50
    1. 2024
    2. Published

      Centennial celebrations of the Danish Pasteur Society

      Høiby, Niels & Bjarnsholt, Thomas, 2024, In: APMIS. 132, 1, p. 3

      Research output: Contribution to journal › Editorial › Research

    3. Published

      In vivo evolution of antimicrobial resistance in a biofilm model of Pseudomonas aeruginosa lung infection

      Higazy, Doaa Mohamed Mohamed E, Pham, A. D., van Hasselt, C., Høiby, Niels, Jelsbak, L., Moser, Claus Ernst & Ciofu, Oana, 2024, In: The ISME Journal. 18, 1

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Louis Pasteur and the birth of microbiology in Denmark

      Høiby, Niels, 2024, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 132, 1, p. 43-52

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. 2023
    6. Published

      Attainment of Target Antibiotic Levels by Oral Treatment of Left-sided Infective Endocarditis: A POET Substudy

      Bock, M., Theut, A. M., van Hasselt, J. G. C., Wang, H., Fuursted, K., Hoiby, N., Lerche, C. J., Ihlemann, N., Gill, S., Christiansen, U., Nielsen, H. L., Lemming, L., Elming, H., Povlsen, J. A., Bruun, N. E., Hofsten, D., Fosbøl, E. L., Kober, L., Schultz, M., Pries-Heje, M. M. & 9 others, Kristensen, J. H., Christensen, J. J., Rosenvinge, F. S., Torp-Pedersen, Christian, Helweg-Larsen, J., Tønder, N., Iversen, Kasper, Bundgård, Henning & Moser, Claus Ernst, 2023, In: Clinical Infectious Diseases. 77, 2, p. 242–251 10 p., 168.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Colistin Enhances Rifampicin's Antimicrobial Action in Colistin-Resistant Pseudomonas aeruginosa Biofilms

      Armengol, E., Kragh, K. N., Tolker-Nielsen, Tim, Sierra, J. M., Higazy, Doaa Mohamed Mohamed E, Ciofu, Oana, Viñas, M. & Høiby, Niels, 2023, In: Antimicrobial Agents and Chemotherapy. 67, 4, e0164122.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Hyperbaric oxygen therapy augments ciprofloxacin effect against Pseudomonas aeruginosa biofilm infected chronic wounds in a mouse model

      Laulund, A. S., Schwartz, F. A., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Calum, Henrik Pierre, Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 5, 100100.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Hyperbaric oxygen therapy counteracts Pseudomonas aeruginosa biofilm micro-compartment phenomenon in murine thermal wounds

      Laulund, A. S., Schwartz, F. A., Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 6, 8 p., 100159.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Rifampicin reduces plasma concentration of linezolid in patients with infective endocarditis

      Bock, M., Van Hasselt, J. G. C., Schwartz, F., Wang, H., Høiby, N., Fuursted, K., Ihlemann, N., Gill, S., Christiansen, U., Bruun, N. E., Elming, H., Povlsen, J. A., Køber, L., Høfsten, D. E., Fosbøl, E. L., Pries-Heje, M. M., Christensen, J. J., Rosenvinge, F. S., Torp-Pedersen, C., Helweg-Larsen, J. & 4 others, Tønder, N., Iversen, Kasper, Bundgård, Henning & Moser, Claus Ernst, 2023, In: The Journal of antimicrobial chemotherapy. 78, 12, p. 2840–2848 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. 2022
    12. Published

      Adaptive Immune Response to Mycobacterium abscessus Complex (MABSC) in Cystic Fibrosis and the Implications of Cross-Reactivity

      Mauch, R. M., Jensen, Peter Østrup, Qvist, T., Kolpen, M., Moser, Claus Ernst, Pressler, T., Nolasco da Silva, M. T., Høiby, Niels & Copenhagen Study Group on Mycobacterial Infections in Cystic Fibrosis, C. S. G. O. M. I. I. C. F., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 858398.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

      Thomsen, K., Kobayashi, O., Kishi, K., Shirai, R., Jensen, Peter Østrup, Heydorn, A., Hentzer, M., Calum, Henrik Pierre, Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 458-476

      Research output: Contribution to journal › Review › Research › peer-review

    14. Published

      Chicken IgY reduces the risk of Pseudomonas aeruginosa urinary tract infections in a murine model

      Schwartz, F. A., Christophersen, L., Thomsen, K., Baekdal, S., Pals Bendixen, M., Jørgensen, M., Bull Rasmussen, I. K., Laulund, A. S., Høiby, Niels & Moser, Claus Ernst, 2022, In: Frontiers in Microbiology. 13, 988386.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Combination and nanotechnology based pharmaceutical strategies for combating respiratory bacterial biofilm infections

      Zhang, L., Bera, H., Wang, H., Wang, J., Guo, Y., Shi, C., Cun, D., Moser, Claus Ernst, Høiby, Niels & Yang, Mingshi, 2022, In: International Journal of Pharmaceutics. 616, 121507.

      Research output: Contribution to journal › Review › Research › peer-review

    16. Published

      Dynamics of a Staphylococcus aureus infective endocarditis simulation model

      Schwartz, F. A., Nielsen, L., Struve Andersen, J., Bock, M., Christophersen, L., Sunnerhagen, T., Lerche, C. J., Bay, Lene, Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 8, p. 515-523

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Effects of antibiotic treatment and phagocyte infiltration on development of Pseudomonas aeruginosa biofilm—Insights from the application of a novel PF hydrogel model in vitro and in vivo

      Wu, H., Song, L., Yam, J. K. H., Plotkin, M., Wang, H., Rybtke, Morten Levin, Seliktar, D., Kofidis, T., Høiby, Niels, Tolker-Nielsen, Tim, Song, Z. & Givskov, Michael, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 826450.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Hyperbaric Oxygen Treatment May Advance the Outcome of Antibiotic Treatment of Biofilm Infections

      Jensen, Peter Østrup, Møller, S. A., Stjernekilde, S., Olsen, P., Moser, Claus Ernst, Schwartz, F. A., Lerche, C. J., Høiby, Niels, Hyldegaard, Ole, Faurholt-jepsen, D. & Kolpen, Mette, 2022, Antibiofilm Strategies: Current and Future Applications to Prevent, Control and Eradicate Biofilms. Springer, p. 201-223 (Antibiofilm Strategies, Vol. 11).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    19. Published

      Immune Response to Biofilm Growing Pulmonary Pseudomonas aeruginosa Infection

      Thomsen, K., Høiby, Niels, Jensen, Peter Østrup, Ciofu, Oana & Moser, Claus Ernst, 2022, In: Biomedicines. 10, 9, 2064.

      Research output: Contribution to journal › Review › Research › peer-review

    20. Published

      Lactoferricin-inspired peptide AMC-109 augments the effect of ciprofloxacin against Pseudomonas aeruginosa biofilm in chronic murine wounds

      Laulund, A. S., Schwartz, F. A., Christophersen, L., Høiby, Niels, Svendsen, J. S. M., Stensen, W., Thomsen, K., Cavanagh, J. P. & Moser, Claus Ernst, 2022, In: Journal of Global Antimicrobial Resistance. 29, p. 185-193 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Murine burn lesion model for studying acute and chronic wound infections

      Calum, Henrik Pierre, Trøstrup, H., Laulund, A. S., Thomsen, K., Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 477-490 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    22. Published

      Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis

      Lerche, C. J., Schwartz, F., Pries-Heje, M. M., Fosbøl, E. L., Iversen, Kasper, Jensen, Peter Østrup, Høiby, Niels, Hyldegaard, Ole, Bundgård, Henning & Moser, Claus Ernst, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 805964.

      Research output: Contribution to journal › Review › Research › peer-review

    23. Published

      Tolerance and resistance of microbial biofilms

      Ciofu, Oana, Moser, Claus Ernst, Jensen, Peter Østrup & Høiby, Niels, 2022, In: Nature Reviews Microbiology. 20, p. 621–635

      Research output: Contribution to journal › Review › Research › peer-review

    24. 2021
    25. Published

      Autologous fibrin sealant co-delivered with antibiotics is a robust method for topical antibiotic treatment after sinus surgery

      Aanæs, Kasper, Nielsen, Kim G., Arndal, E., von Buchwald, Christian, Pressler, T. & Høiby, Niels, 1 Feb 2021, In: Acta Oto-Laryngologica. 141, 2, p. 181-186 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Adjunctive S100A8/A9 Immunomodulation Hinders Ciprofloxacin Resistance in Pseudomonas aeruginosa in a Murine Biofilm Wound Model

      Laulund, A. S., Schwartz, F., Trøstrup, H., Thomsen, K., Christophersen, L., Calum, Henrik Pierre, Ciofu, Oana, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cellular and Infection Microbiology. 11, 652012.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Anti-biofilm Approach in Infective Endocarditis Exposes New Treatment Strategies for Improved Outcome

      Lerche, C. J., Schwartz, F., Theut, M., Fosbøl, E. L., Iversen, Kasper, Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2021, In: Frontiers in Cell and Developmental Biology. 9, 25 p., 643335.

      Research output: Contribution to journal › Review › Research › peer-review

    28. Published

      Azithromycin potentiates avian IgY effect against Pseudomonas aeruginosa in a murine pulmonary infection model

      Thomsen, K., Christophersen, L., Lerche, C. J., Holmgaard, D. B., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2021, In: International Journal of Antimicrobial Agents. 57, 1, 106213.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Distinct contribution of hyperbaric oxygen therapy to human neutrophil function and antibiotic efficacy against Staphylococcus aureus

      Schwartz, F. A., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Laulund, A. S., Woetmann, Anders , Høiby, Niels & Moser, Claus Ernst, 2021, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 129, 9, p. 566-573

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Maintaining normal lung function in children with cystic fibrosis is possible with aggressive treatment regardless of Pseudomonas aeruginosa infections

      Hansen, C. R., Gilljam, M., Olesen, H. V., Høiby, Niels, Karpati, F., Johansson, E., Krantz, C., Skov, M., Pressler, T. & Lindblad, A., 2021, In: Acta Pædiatrica. 110, 9, p. 2607-2609 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Novel human in vitro vegetation simulation model for infective endocarditis

      Schwartz, F. A., Christophersen, L., Laulund, A. S., Lundquist, R., Lerche, C., Rude Nielsen, P., Bundgård, Henning, Høiby, Niels & Moser, Claus Ernst, 2021, In: APMIS. 129, 11, p. 653-662 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      SARS-CoV-2 infection dynamics in Denmark, February through October 2020: Nature of the past epidemic and how it may develop in the future

      Rasmussen, S., Petersen, M. S. & Høiby, Niels, 2021, In: PLoS ONE. 16, 4 April, e0249733.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. 2020
    34. Published

      Antibody response against Pseudomonas aeruginosa and its relationship with immune mediators in the upper and lower airways of cystic fibrosis patients

      Mauch, R. M., Hentschel, J., Aanæs, Kasper, Barucha, A., Nolasco da Silva, M. T., Levy, C. E., Høiby, Niels & Mainz, J. G., 2020, In: Pediatric Pulmonology. 55, 4, p. 959-967

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

      Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology

      Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Further Commentary

      Hengzhuang, W. & Høiby, Niels, 2020, In: Pediatric Pulmonology. 55, 1, 1 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    38. Published

      In vivo demonstration of Pseudomonas aeruginosa biofilms as independent pharmacological microcompartments

      Christophersen, L., Schwartz, F. A., Lerche, C. J., Svanekjær, T., Kragh, K. N., Laulund, A. S., Thomsen, K., Henneberg, K. Å., Sams, T., Høiby, Niels & Moser, Claus Ernst, 2020, In: Journal of Cystic Fibrosis. 19, 6, p. 996-1003

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs

      Arndal, E., Johansen, Helle Krogh, Haagensen, J. A. J., Bartell, J. A., Marvig, R. L., Alanin, M., Aanæs, Kasper, Høiby, Niels, Nielsen, Kim G., Backer, Vibeke & von Buchwald, Christian, 2020, In: The European Respiratory Journal. 55, 1, 4 p., 1901472.

      Research output: Contribution to journal › Letter › Research › peer-review

    40. Published

      Pseudomonas aeruginosa antibody response in cystic fibrosis decreases rapidly following lung transplantation

      Schwensen, H. F., Moser, Claus Ernst, Perch, Michael, Pressler, T. & Høiby, Niels, 2020, In: Journal of Cystic Fibrosis. 19, 4, p. 587-594

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      The evolutionary trajectories of P. aeruginosa in biofilm and planktonic growth modes exposed to ciprofloxacin: beyond selection of antibiotic resistance

      Ahmed, M. N., Abdelsamad, A., Wassermann, T., Porse, A., Becker, J., Sommer, M. O. A., Høiby, Niels & Ciofu, Oana, 2020, In: npj Biofilms and Microbiomes. 6, 1, 10 p., 28.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. 2019
    43. Published

      P. aeruginosa flow-cell biofilms are enhanced by repeated phage treatments but can be eradicated by phage-ciprofloxacin combination: —monitoring the phage–P. aeruginosa biofilms interactions

      Henriksen, K., Rørbo, N., Rybtke, Morten Levin, Martinet, M. G., Tolker-Nielsen, Tim, Høiby, Niels, Middelboe, Mathias & Ciofu, Oana, 2019, In: Pathogens and Disease. 77, 2, 11 p., ftz011.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Goetze, J. P., Nielsen, P. R., Thomsen, K., Enevold, C., Høiby, Niels, Jensen, Peter Østrup, Bundgård, Henning & Moser, Claus Ernst, 2019, In: PLoS ONE. 14, 4, 16 p., e0215333.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Antibiotic therapy as personalized medicine - general considerations and complicating factors

      Moser, Claus Ernst, Lerche, C. J., Thomsen, K., Hartvig, T., Schierbeck, J., Jensen, Peter Østrup, Ciofu, Oana & Høiby, Niels, 2019, In: APMIS. 127, 5, p. 361-371

      Research output: Contribution to journal › Review › Research › peer-review

    46. Published

      Antibody response against Mycobacterium avium complex in cystic fibrosis patients measured by a novel IgG ELISA test

      Ravnholt, C., Qvist, T., Kolpen, M., Pressler, T., Skov, M. & Høiby, Niels, 2019, In: Journal of Cystic Fibrosis. 18, 4, p. 516-521

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

      Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Editorial comment

      Moser, Claus Ernst, Song, Z. & Høiby, Niels, 2019, In: APMIS. 127, 5, 1 p.

      Research output: Contribution to journal › Editorial › Research › peer-review

    49. Published

      Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth

      Høiby, Niels, Henneberg, K. Å., Wang, H., Stavnsbjerg, Camilla, Bjarnsholt, Thomas, Ciofu, Oana, Johansen, U. R. & Sams, T., 2019, In: International Journal of Antimicrobial Agents. 53, 5, p. 564-573

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

      Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air

      Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Lack of the Major Multifunctional Catalase KatA in Pseudomonas aeruginosa Accelerates Evolution of Antibiotic Resistance in Ciprofloxacin-Treated Biofilms

      Ahmed, M. N., Porse, A., Abdelsamad, A., Sommer, M., Høiby, Niels & Ciofu, Oana, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 10, 12 p., e00766-19.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Optimization of colistin dosing regimen for cystic fibrosis patients with chronic Pseudomonas aeruginosa biofilm lung infections

      Hengzhuang, W., Green, K., Pressler, T., Skov, M., Katzenstein, T. L., Wu, X. & Høiby, Niels, 2019, In: Pediatric Pulmonology. 54, 5, p. 575-580

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Secretory IgA-mediated immune response in saliva and early detection of Pseudomonas aeruginosa in the lower airways of pediatric cystic fibrosis patients

      Mauch, R. M., Rossi, C. L., Nolasco da Silva, M. T., Bianchi Aiello, T., Ribeiro, J. D., Ribeiro, A. F., Høiby, Niels & Levy, C. E., 2019, In: Medical Microbiology and Immunology. 208, 2, p. 205-213 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. 2018
    56. Published

      Evolution of Antibiotic Resistance in Biofilm and Planktonic Pseudomonas aeruginosa Populations Exposed to Subinhibitory Levels of Ciprofloxacin

      Ahmed, M. N. A., Porse, A., Sommer, M., Høiby, Niels & Ciofu, Oana, 1 Aug 2018, In: Antimicrobial Agents and Chemotherapy. 62, 8, 12 p., e00320-18.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor

      Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132

      Research output: Contribution to journal › Journal article › Research › peer-review

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