Peter Østrup Jensen

Peter Østrup Jensen

Associate Professor

Member of:


    1. 2024
    2. E-pub ahead of print

      Bacterial aerobic respiration is a major consumer of oxygen in sputum from patients with acute lower respiratory tract infection

      Jensen, Peter Østrup, Olsen, P., Dungu, A. M., Egelund, G. B., Jensen, A. V., Ravn, P., Lindegaard, Birgitte, Hertz, Frederik Boëtius, Bjarnsholt, Thomas, Faurholt-Jepsen, D. & Kolpen, Mette, 2024, (E-pub ahead of print) In: APMIS.

      Research output: Contribution to journalJournal articlepeer-review

    3. 2023
    4. Published

      3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism

      Adams, Yvonne, Clausen, Anne Skovsbo, Jensen, Peter Østrup, Lager, M., Wilhelmsson, P., Henningson, A. J., Lindgren, P. E., Faurholt-Jepsen, D., Mens, H., Kraiczy, P., Kragh, K. N., Bjarnsholt, Thomas, Kjær, Andreas, Lebech, Anne-Mette & Jensen, Anja Ramstedt, 2023, In: iScience. 26, 1, 105838.

      Research output: Contribution to journalJournal articlepeer-review

    5. Published
    6. Published

      “The standard procedure” for Investigation of Oral Neutrophils in Oral Diseases

      Jensen, Peter Østrup, Rikvold, P. D., Larsen, Kristine Røn, Jørgensen, Mette Rose & Kragelund, C., 2023, In: International Journal of Dentistry. 2023, 6 p., 1308326.

      Research output: Contribution to journalJournal articlepeer-review

    7. Published

      Antimicrobial resistance of Pseudomonas aeruginosa in a cystic fibrosis population after introduction of a novel cephalosporin/β-lactamase inhibitor combination

      Katzenstein, T. L., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup, Pressler, T., Johansen, Helle Krogh & Kolpen, Mette, 2023, In: APMIS. 131, 8, p. 419-425

      Research output: Contribution to journalJournal articlepeer-review

    8. Published

      Hyperbaric oxygen therapy augments ciprofloxacin effect against Pseudomonas aeruginosa biofilm infected chronic wounds in a mouse model

      Laulund, A. S., Schwartz, F. A., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Calum, Henrik Pierre, Høiby, Niels, Thomsen, K. & Moser, Claus Ernst, 2023, In: Biofilm. 5, 100100.

      Research output: Contribution to journalJournal articlepeer-review

    9. 2022
    10. Published

      The importance of understanding the infectious microenvironment

      Bjarnsholt, Thomas, Whiteley, M., Rumbaugh, K. P., Stewart, P. S., Jensen, Peter Østrup & Frimodt-Møller, N., 2022, In: The Lancet Infectious Diseases. 22, 3, p. e88-e92

      Research output: Contribution to journalReviewpeer-review

    11. Published

      Tolerance and resistance of microbial biofilms

      Ciofu, Oana, Moser, Claus Ernst, Jensen, Peter Østrup & Høiby, Niels, 2022, In: Nature Reviews Microbiology. 20, p. 621–635

      Research output: Contribution to journalReviewpeer-review

    12. Published

      Hyperbaric Oxygen Treatment May Advance the Outcome of Antibiotic Treatment of Biofilm Infections

      Jensen, Peter Østrup, Møller, S. A., Stjernekilde, S., Olsen, P., Moser, Claus Ernst, Schwartz, F. A., Lerche, C. J., Høiby, Niels, Hyldegaard, Ole, Faurholt-jepsen, D. & Kolpen, Mette, 2022, Antibiofilm Strategies: Current and Future Applications to Prevent, Control and Eradicate Biofilms. Springer, p. 201-223 (Antibiofilm Strategies, Vol. 11).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    13. Published

      Increased sputum lactate during oral glucose tolerance test in cystic fibrosis

      Jensen, Peter Østrup, Nielsen, B. U., Kolpen, Mette, Pressler, T., Faurholt-Jepsen, D. & Mathiesen, I. H. M., 2022, In: APMIS. 130, 8, p. 535-539

      Research output: Contribution to journalJournal articlepeer-review

    14. Published

      Bacterial biofilms predominate in both acute and chronic human lung infections

      Kolpen, Mette, Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, P., Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: European Respiratory Journal. Supplement. 60, Suppl. 66, 4.

      Research output: Contribution to journalJournal articlepeer-review

    15. Published

      Bacterial biofilms predominate in both acute and chronic human lung infections

      Kolpen, M., Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, Pernille, Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: Thorax. 77, p. 1015–1022

      Research output: Contribution to journalJournal articlepeer-review

    16. Published

      Endotracheal lactate reflects lower respiratory tract infections and inflammation in intubated patients

      Kolpen, M., Dalby Sørensen, C., Faurholt-Jepsen, D., Hertz, Frederik Boëtius, Jensen, Peter Østrup & Bestle, Morten Heiberg, 2022, In: APMIS. 130, 8, p. 507-514

      Research output: Contribution to journalJournal articlepeer-review

    17. Published

      Prevalence of biofilms in acute infections challenges a longstanding paradigm

      Kolpen, M., Jensen, Peter Østrup, Faurholt-Jepsen, D. & Bjarnsholt, Thomas, 2022, In: Biofilm. 4, 100080.

      Research output: Contribution to journalJournal articlepeer-review

    18. Published

      Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis

      Lerche, C. J., Schwartz, F., Pries-Heje, M. M., Fosbøl, E. L., Iversen, Kasper, Jensen, Peter Østrup, Høiby, Niels, Hyldegaard, Ole, Bundgård, Henning & Moser, Claus Ernst, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 805964.

      Research output: Contribution to journalReviewpeer-review

    19. Published

      The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment

      Lichtenberg, Mads, Jakobsen, Tim Holm, Kühl, Michael, Kolpen, Mette, Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: FEMS Microbiology Reviews. 46, 5, 13 p., fuac018.

      Research output: Contribution to journalJournal articlepeer-review

    20. Published

      Adaptive Immune Response to Mycobacterium abscessus Complex (MABSC) in Cystic Fibrosis and the Implications of Cross-Reactivity

      Mauch, R. M., Jensen, Peter Østrup, Qvist, T., Kolpen, M., Moser, Claus Ernst, Pressler, T., Nolasco da Silva, M. T., Høiby, Niels & Copenhagen Study Group on Mycobacterial Infections in Cystic Fibrosis, C. S. G. O. M. I. I. C. F., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 858398.

      Research output: Contribution to journalJournal articlepeer-review

    21. Published

      A novel Borrelia-specific real-time PCR assay is not suitable for diagnosing Lyme neuroborreliosis

      Pedersen, Regitze Renee, Kragh, K. N., Fritz, Blaine Gabriel, Ørbæk, M., Jensen, Peter Østrup, Lebech, Anne-Mette & Bjarnsholt, Thomas, 2022, In: Ticks and Tick-borne Diseases. 13, 5, 101971.

      Research output: Contribution to journalJournal articlepeer-review

    22. Published

      Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

      Thomsen, K., Kobayashi, O., Kishi, K., Shirai, R., Jensen, Peter Østrup, Heydorn, A., Hentzer, M., Calum, Henrik Pierre, Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 458-476

      Research output: Contribution to journalReviewpeer-review

    23. Published

      Immune Response to Biofilm Growing Pulmonary Pseudomonas aeruginosa Infection

      Thomsen, K., Høiby, Niels, Jensen, Peter Østrup, Ciofu, Oana & Moser, Claus Ernst, 2022, In: Biomedicines. 10, 9, 2064.

      Research output: Contribution to journalReviewpeer-review

    24. 2021
    25. Published

      Catalase protects biofilm of Staphylococcus aureus against daptomycin activity

      El Haj, C., Lichtenberg, Mads, Nielsen, K. L., Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: Antibiotics. 10, 5, 511.

      Research output: Contribution to journalJournal articlepeer-review

    26. Published

      Hyperbaric oxygen treatment impacts oxidative stress markers in patients with necrotizing soft-tissue infection

      Hedetoft, M., Jensen, Peter Østrup, Moser, Claus Ernst, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Investigative Medicine. 69, 7, p. 1330-1338

      Research output: Contribution to journalJournal articlepeer-review

    27. Published

      Soluble ICAM-1 is modulated by hyperbaric oxygen treatment and correlates with disease severity and mortality in patients with necrotizing soft-tissue infection

      Hedetoft, M., Moser, Claus Ernst, Jensen, Peter Østrup, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Applied Physiology. 130, 3, p. 729-736 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    28. Published

      Misleading mental models: Ceci n’est pas un biofilm

      Jensen, Peter Østrup & Rumbaugh, K., 2021, In: APMIS. 129, 10, p. 577-578 2 p.

      Research output: Contribution to journalEditorialpeer-review

    29. Published

      Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa

      Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.

      Research output: Contribution to journalJournal articlepeer-review

    30. Published

      Immune Responses to Pseudomonas aeruginosa Biofilm Infections

      Moser, Claus Ernst, Jensen, Peter Østrup, Thomsen, K., Kolpen, M., Rybtke, Morten Levin, Lauland, A. S., Trøstrup, H. & Tolker-Nielsen, Tim, 2021, In: Frontiers in Immunology. 12, 625597.

      Research output: Contribution to journalReviewpeer-review

    31. Published

      Delayed neutrophil recruitment allows nascent Staphylococcus aureus biofilm formation and immune evasion

      Pettygrove, B. A., Kratofil, R. M., Alhede, M., Jensen, Peter Østrup, Newton, M., Qvortrup, Klaus, Pallister, K. B., Bjarnsholt, Thomas, Kubes, P., Voyich, J. M. & Stewart, P. S., Aug 2021, In: Biomaterials. 275, 13 p., 120775.

      Research output: Contribution to journalJournal articlepeer-review

    32. Published
    33. Published

      Distinct contribution of hyperbaric oxygen therapy to human neutrophil function and antibiotic efficacy against Staphylococcus aureus

      Schwartz, F. A., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Laulund, A. S., Woetmann, Anders , Høiby, Niels & Moser, Claus Ernst, 2021, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 129, 9, p. 566-573

      Research output: Contribution to journalJournal articlepeer-review

    34. 2020
    35. Published

      Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes

      Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, Lene & Bjarnsholt, Thomas, 2020, In: Medical Microbiology and Immunology. 209, p. 669–680

      Research output: Contribution to journalJournal articlepeer-review

    36. Published

      The origin of extracellular DNA in bacterial biofilm infections in vivo

      Alhede, M., Alhede, M., Qvortrup, Klaus, Kragh, K. N., Jensen, Peter Østrup, Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Pathogens and Disease. ftaa018.

      Research output: Contribution to journalJournal articlepeer-review

    37. Published

      Human immune cell mobilization during exercise: effect of IL-6 receptor blockade

      Bay, M. L., Heywood, S., Wedell-Neergaard, A. S., Schauer, T., Lehrskov, L. L., Christensen, R. H., Legård, G. E., Jensen, Peter Østrup, Krogh-Madsen, Rikke & Ellingsgaard, H., 2020, In: Experimental Physiology. 105, 12, p. 2086-2098 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    38. Published

      Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology

      Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653

      Research output: Contribution to journalJournal articlepeer-review

    39. Published
    40. Published

      Lactobacillus rhamnosus strains of oral and vaginal origin show strong antifungal activity in vitro

      Jørgensen, Mette Rose, Rikvold, P. T., Lichtenberg, Mads, Jensen, Peter Østrup, Kragelund, C. & Twetman, Svante, 2020, In: Journal of Oral Microbiology. 12, 1, 8 p., 1832832.

      Research output: Contribution to journalJournal articlepeer-review

    41. Published

      Staphylococcus aureus augments release of matrix metalloproteinase-8 from human polymorphonuclear leukocytes

      Kirketerp-Møller, K., Bjarnsholt, Thomas, Jensen, Peter Østrup & Ågren, Magnus, 2020, In: Acta Dermato-Venereologica. 100, 15, p. 1-2 2 p., adv00232.

      Research output: Contribution to journalJournal articlepeer-review

    42. Published

      Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

      Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

      Research output: Contribution to journalJournal articlepeer-review

    43. Published

      Neutrophil count in sputum is associated with increased sputum glucose and sputum L-lactate in cystic fibrosis

      Nielsen, B. U., Kolpen, M., Jensen, Peter Østrup, Katzenstein, T., Pressler, T., Ritz, C., Mathiesen, I. H. M. & Faurholt-Jepsen, D., 2020, In: P L o S One. 15, 9, 12 p., e0238524.

      Research output: Contribution to journalJournal articlepeer-review

    44. 2019
    45. Published

      Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction

      Bjarnsholt, Thomas, Jensen, Peter Østrup & Alhede, M., 2019, In: Pathogens and Disease. 77, 5, ftz052.

      Research output: Contribution to journalJournal articlepeer-review

    46. Published

      Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms

      Crabbé, A., Jensen, Peter Østrup, Bjarnsholt, Thomas & Coenye, T., 2019, In: Trends in Microbiology. 27, 10, p. 850-863

      Research output: Contribution to journalReviewpeer-review

    47. Published

      ADDITION OF GLUCOSE PROVIDES MYCOBACTERIUM ABSCESSUS BIOFILM WITH PROTECTION AGAINST AMIKACIN

      Demant, M., Kristensen, S., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup & Kolpen, M., 2019, In: Pediatric Pulmonology. 54, S2, p. S298-S299

      Research output: Contribution to journalConference abstract in journalpeer-review

    48. Published

      The inflamed sputum in lower respiratory tract infection: l-lactate levels are correlated to neutrophil accumulation

      Fredman, G., Kolpen, Mette, Hertz, F. B., Petersen, P. T., Jensen, A. V., Baunbæk-Egelund, G., Ravn, Pernille, Jensen, Peter Østrup & Faurholt-Jepsen, D., 2019, In: APMIS. 127, 2, p. 72-79

      Research output: Contribution to journalJournal articlepeer-review

    49. Published

      Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air

      Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-jepsen, D., Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.

      Research output: Contribution to journalJournal articlepeer-review

    50. Published

      Oxygen restriction generates difficult-to-culture p. Aeruginosa

      Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, K. N., Kolpen, Mette, Sønderholm, M., Andersson, M., Koch, A., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.

      Research output: Contribution to journalJournal articlepeer-review

    51. Published

      Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Goetze, J. P., Nielsen, P. R., Thomsen, K., Enevold, C., Høiby, Niels, Jensen, Peter Østrup, Bundgård, Henning & Moser, Claus Ernst, 2019, In: PLoS ONE. 14, 4, 16 p., e0215333.

      Research output: Contribution to journalJournal articlepeer-review

    52. Published

      Markers of bone turnover are reduced in patients with CF related diabetes; the role of glucose

      Mathiesen, I. H., Hitz, Mette Friberg, Katzenstein, T. L., Oturai, P., Skov, M., Jørgensen, Niklas Rye, Jensen, Peter Østrup, Mikkelsen, C. R., Krogh-Madsen, Rikke, Pressler, T. & Faurholt-Jepsen, D., 2019, In: Journal of Cystic Fibrosis. 18, 3, p. 436-441

      Research output: Contribution to journalJournal articlepeer-review

    53. Published

      Antibiotic therapy as personalized medicine - general considerations and complicating factors

      Moser, Claus Ernst, Lerche, C. J., Thomsen, K., Hartvig, T., Schierbeck, J., Jensen, Peter Østrup, Ciofu, Oana & Høiby, Niels, 2019, In: APMIS. 127, 5, p. 361-371

      Research output: Contribution to journalReviewpeer-review

    54. Published

      Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

      Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664

      Research output: Contribution to journalJournal articlepeer-review

    55. 2018
    56. Published

      Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms

      Gade, P. A. V., Olsen, T. B., Jensen, Peter Østrup, Kolpen, Mette, Høiby, Niels, Henneberg, K. Å. & Sams, T., 2018, In: PLoS ONE. 13, 6, 16 p., e0198909.

      Research output: Contribution to journalJournal articlepeer-review

    57. Published

      Implants induce a new niche for microbiomes

      Jakobsen, Tim Holm, Eickhardt, S. R., Gheorghe, Alexandra Gabriella, Stenqvist, C., Sønderholm, M., Stavnsberg, C., Jensen, Peter Østrup, Odgaard, Anders, Whiteley, M., Moser, Claus Ernst, Hvolris, J., Hougen, H. P. & Bjarnsholt, Thomas, 1 Aug 2018, In: APMIS - Journal of Pathology, Microbiology and Immunology. 126, 8, p. 685-692 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    58. Published

      Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis

      Mauch, R. M., Jensen, Peter Østrup, Moser, Claus Ernst, Levy, C. E. & Høiby, Niels, 2018, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17, 2, p. 143-152

      Research output: Contribution to journalReviewpeer-review

    59. Published

      Extracellular hydrogen peroxide measurements using a flow injection system in combination with microdialysis probes – potential and challenges

      Moßhammer, Maria, Schrameyer, V., Jensen, Peter Østrup, Koren, K. & Kühl, Michael, 2018, In: Free Radical Biology & Medicine. 128, p. 111-123

      Research output: Contribution to journalJournal articlepeer-review

    60. Published

      Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model

      Sønderholm, M., Koren, K., Wangpraseurt, D., Jensen, Peter Østrup, Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas & Kühl, Michael, 2018, In: npj Biofilms and Microbiomes. 4, 11 p., 3.

      Research output: Contribution to journalJournal articlepeer-review

    61. Published

      Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor

      Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132

      Research output: Contribution to journalJournal articlepeer-review

    62. 2017
    63. Published

      Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase

      Damgaard, D., Bjørn, M. E., Jensen, Peter Østrup & Nielsen, Claus Henrik, Dec 2017, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 1203-1208 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    64. Published

      Use of Oxygen Therapies in Wound Healing: Focus on Topical and Hyperbaric Oxygen Treatment

      Gottrup, F., Dissemond, J., Baines, C., Frykberg, R., Jensen, Peter Østrup, Kot, J., Kröger, K. & Longobardi, P., 1 May 2017, In: Journal of Wound Care. 26, Sup5, p. S1-S43

      Research output: Contribution to journalJournal articlepeer-review

    65. Published

      Diagnosis of biofilm infections in cystic fibrosis patients

      Høiby, Niels, Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup, Kolpen, Mette, Qvist, T., Aanæs, Kasper, Pressler, T., Skov, M. & Ciofu, Oana, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 339-343 5 p.

      Research output: Contribution to journalReviewpeer-review

    66. Published

      Microenvironmental characteristics and physiology of biofilms in chronic infections of CF patients are strongly affected by the host immune response

      Jensen, Peter Østrup, Kolpen, Mette, Kragh, K. N. & Kühl, Michael, 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 276–288 13 p.

      Research output: Contribution to journalReviewpeer-review

    67. Published

      Probiotic Lactobacillus reuteri has antifungal effects on oral Candida species in vitro

      Jørgensen, Mette Rose, Kragelund, C., Jensen, Peter Østrup, Keller, M. K. & Twetman, Svante, 2017, In: Journal of Oral Microbiology. 9, 1, 8 p., 1274582.

      Research output: Contribution to journalJournal articlepeer-review

    68. Published

      O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM

      Kolpen, M., Ravnholt, C., Qvist, T., Kragh, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.

      Research output: Contribution to journalConference abstract in journalpeer-review

    69. Published

      Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin

      Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.

      Research output: Contribution to journalJournal articlepeer-review

    70. Published

      Hyperbaric oxygen treatment augments tobramycin efficacy in experimental staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Kolpen, Mette, Nielsen, P. R., Trøstrup, H., Thomsen, K., Hyldegaard, Ole, Bundgård, Henning, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Antimicrobial Agents. 50, 3, p. 406-412

      Research output: Contribution to journalJournal articlepeer-review

    71. Published

      Biofilms and host response - helpful or harmful

      Moser, Claus Ernst, Pedersen, H. T., Lerche, C. J., Kolpen, Mette, Line, L., Thomsen, K., Høiby, Niels & Jensen, Peter Østrup, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 320-338 19 p.

      Research output: Contribution to journalReviewpeer-review

    72. Published

      Heading for centennial anniversary and beyond

      Norrild, B., Ralfkiaer, E., Bjarnsholt, Thomas & Jensen, Peter Østrup, Dec 2017, In: APMIS. 125, 12, p. 1133-1133

      Research output: Contribution to journalEditorial

    73. Published

      Pseudomonas aeruginosa aggregate formation in an alginate bead model system exhibits In Vivo-like characteristics

      Sønderholm, M., Kragh, K. N., Koren, K., Jakobsen, Tim Holm, Darch, S., Alhede, M., Jensen, Peter Østrup, Whiteley, M., Kühl, Michael & Bjarnsholt, Thomas, May 2017, In: Applied and Environmental Microbiology. 83, 9, 15 p., e00113-17.

      Research output: Contribution to journalJournal articlepeer-review

    74. Published

      The consequences of being in an infectious biofilm – microenvironmental conditions governing antibiotic tolerance

      Sønderholm, M., Bjarnsholt, Thomas, Alhede, M., Kolpen, Mette, Jensen, Peter Østrup, Kühl, Michael & Kragh, K. N., 2017, In: International Journal of Molecular Sciences. 18, 12, 14 p., 2688.

      Research output: Contribution to journalReviewpeer-review

    75. Published

      Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines—implications for delayed wound closure?

      Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Oct 2017, In: Pathogens and Disease. 75, 7, 10 p., ftx068.

      Research output: Contribution to journalJournal articlepeer-review

    76. Published

      Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds

      Trøstrup, H., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Molecular Sciences. 18, 7, 13 p., 1359.

      Research output: Contribution to journalJournal articlepeer-review

    77. 2016
    78. Published

      Diffusion retardation by binding of tobramycin in an alginate biofilm model

      Cao, B., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Sneppen, Kim, Høiby, Niels, Moser, Claus Ernst & Sams, T., 21 Apr 2016, In: P L o S One. 11, 4, 11 p., e0153616.

      Research output: Contribution to journalJournal articlepeer-review

    79. Published

      Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice

      Damlund, D. S. M., Christophersen, L., Jensen, Peter Østrup, Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2016, In: APMIS - Journal of Pathology, Microbiology and Immunology. 124, 6, p. 500-507 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    80. Published

      Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

      Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.

      Research output: Contribution to journalJournal articlepeer-review

    81. Published

      Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment

      Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.

      Research output: Contribution to journalLetterpeer-review

    82. Published

      Development of a rechargeable optical hydrogen peroxide sensor - sensor design and biological application

      Koren, K., Jensen, Peter Østrup & Kühl, Michael, 2016, In: Analyst. 141, 14, p. 4332-4339 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    83. Published

      Role of multicellular aggregates in biofilm formation

      Kragh, K. N., Hutchison, J. B., Melaugh, G., Rodesney, C., Roberts, A. E. L., Irie, Y., Jensen, Peter Østrup, Diggle, S. P., Allen, R. J., Gordon, V. & Bjarnsholt, Thomas, 22 Mar 2016, In: mBio. 7, 2, 11 p., e00237-16.

      Research output: Contribution to journalJournal articlepeer-review

    84. Published

      Incidence of Propionibacterium acnes in initially culture-negative thioglycollate broths: a prospective cohort study at a Danish University Hospital

      Kvich, Lasse Andersson, Jensen, Peter Østrup, Justesen, U. S. & Bjarnsholt, Thomas, Nov 2016, In: Clinical Microbiology and Infection. 22, 11, p. 941-945

      Research output: Contribution to journalJournal articlepeer-review

    85. Published

      Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    86. Published

      Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils

      Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    87. 2015
    88. Published

      Antibiofilm Properties of Acetic Acid

      Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    89. Published

      Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model

      Cao, B., Christophersen, L., Thomsen, K., Sønderholm, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2015, In: The Journal of antimicrobial chemotherapy. 70, 7, p. 2057-2063 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    90. Published

      Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

      Ciofu, Oana, Tolker-Nielsen, Tim, Jensen, Peter Østrup, Wang, H. & Høiby, Niels, 2015, In: Advanced Drug Delivery Reviews. 85, p. 7-23 17 p.

      Research output: Contribution to journalReviewpeer-review

    91. Published

      Denitrification by cystic fibrosis pathogens - Stenotrophomonas maltophilia is dormant in sputum

      Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas, Line, L., Hansen, C. R., Dalbøge, C. S., Hansen, N., Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2015, In: International Journal of Medical Microbiology. 305, 1, p. 1-10 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    92. Published

      Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Trøstrup, H., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Bundgaard, H., Høiby, Niels & Moser, C., 1 Dec 2015, In: European Journal of Clinical Microbiology & Infectious Diseases. 34, 12, p. 2349-2357 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    93. Published

      The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

      Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    94. Published

      Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    95. 2014
    96. Published

      Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation

      Brochmann, R. P., Toft, A., Ciofu, Oana, Briales, A., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, 2014, In: International Journal of Antimicrobial Agents. 43, 2, p. 140-147 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    97. Published

      Plasmodium falciparum avoids change in erythrocytic surface expression of phagocytosis markers during inhibition of nitric oxide synthase activity

      Hempel, C., Kohnke, H., Maretty, L., Jensen, Peter Østrup, Staalsø, Trine & Kurtzhals, Jørgen, Nov 2014, In: Molecular and Biochemical Parasitology. 198, 1, p. 29-36 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    98. Published

      Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms

      Jensen, Peter Østrup, Briales, A., Brochmann, R. P., Wang, H., Kragh, K. N., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Ciofu, Oana, 2014, In: Pathogens and Disease. 70, 3, p. 440-443 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    99. Published

      Exhaled breath analysis using electronic nose in cystic fibrosis and primary ciliary dyskinesia patients with chronic pulmonary infections

      Joensen, O., Paff, T., Haarman, E. G., Skovgaard, I. M., Jensen, Peter Østrup, Bjarnsholt, Thomas & Nielsen, Kim G., 2014, In: PLOS ONE. 9, 12, p. 1-15 15 p., e115584.

      Research output: Contribution to journalJournal articlepeer-review

    100. Published

      Nitric oxide production by polymorphonuclear leukocytes in infected cystic fibrosis sputum consumes oxygen

      Kolpen, Mette, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Rickelt, L. F., Kühl, Michael, Hempel, C., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Clinical and Experimental Immunology. 177, 1, p. 310–319 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    101. Published

      Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

      Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: PLOS ONE. 9, 1, p. e84353 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    102. Published

      Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients

      Kragh, K. N., Alhede, M., Jensen, Peter Østrup, Moser, Claus Ernst, Scheike, Thomas, Jacobsen, C. S., Poulsen, Steen Seier, Eickhardt-Sørensen, S. R., Trostrup, H., Christoffersen, L., Hougen, H. P., Rickelt, L. F., Kühl, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2014, In: Infection and Immunity. 82, 11, p. 4477-4486 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    103. Published

      Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum

      Line, L., Alhede, M., Kolpen, Mette, Kühl, Michael, Ciofu, Oana, Bjarnsholt, Thomas, Moser, Claus Ernst, Toyofuku, M., Nomura, N., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Frontiers in Microbiology. 5, 11 p., 554.

      Research output: Contribution to journalJournal articlepeer-review

    104. 2013
    105. Published

      The in vivo biofilm

      Bjarnsholt, Thomas, Alhede, M., Alhede, M., Eickhardt-Sørensen, S. R., Moser, Claus Ernst, Kühl, Michael, Jensen, Peter Østrup & Høiby, Niels, 2013, In: Trends in Microbiology. 21, 9, p. 466-474 9 p.

      Research output: Contribution to journalReviewpeer-review

    106. Published

      Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model

      Cavanagh, J. P., Granslo, H. N., Fredheim, E. A., Christophersen, L., Jensen, Peter Østrup, Thomsen, K., van Gennip, M., Klingenberg, C., Flaegstad, T., Moser, Claus Ernst & Alhede, M., Sep 2013, In: The Journal of antimicrobial chemotherapy. 68, 9, p. 2106-10 5 p.

      Research output: Contribution to journalJournal articlepeer-review

    107. Published

      Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms

      Chiang, W., Nilsson, M., Jensen, Peter Østrup, Høiby, Niels, Nielsen, T., Givskov, Michael & Tolker-Nielsen, Tim, May 2013, In: Antimicrobial Agents and Chemotherapy. 57, 5, p. 2352-61 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    108. Published

      Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes

      Jakobsen, T. H., Hansen, M. A., Jensen, P. Ø., Hansen, L., Riber, L., Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, K., Burmølle, M., Moser, C. E., Kühl, M., Ciofu, O., Givskov, M., Sørensen, S. J. & 2 others, Høiby, Niels & Bjarnsholt, Thomas, 2013, In: P L o S One. 8, 7, 17 p., e68484.

      Research output: Contribution to journalJournal articlepeer-review

    109. Published

      Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors

      Jakobsen, Tim Holm, Bjarnsholt, Thomas, Jensen, Peter Østrup, Givskov, Michael & Høiby, Niels, Jul 2013, In: Future Microbiology. 8, 7, p. 901-21 21 p.

      Research output: Contribution to journalJournal articlepeer-review

    110. Published

      Sublethal ciprofloxacin treatment leads to rapid development of high-level ciprofloxacin resistance during long-term experimental evolution of Pseudomonas aeruginosa

      Jørgensen, K. M., Wassermann, T., Jensen, Peter Østrup, Hengzuang, W., Molin, S., Høiby, Niels & Ciofu, Oana, Sep 2013, In: Antimicrobial Agents and Chemotherapy. 57, 9, p. 4215-21 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    111. Published

      Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model

      Trøstrup, H., Thomsen, K., Christophersen, L. J., Hougen, H. P., Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    112. 2012
    113. Published

      Process for the manufacture of ajoene derivatives

      Bjarnsholt, Thomas, Høiby, Niels, Jensen, Peter Østrup, Phipps, R., Shanmugham, Meenakshi, S., Alhede, M., Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Tanner, D., Larsen, Thomas, O. & Givskov, Michael, 14 Jun 2012, IPC No. C07C 323/ 65 A I, Patent No. WO2012076016, Priority date 8 Dec 2010, Priority No. EP20100194154

      Research output: Patent

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