Peter Østrup Jensen

Peter Østrup Jensen

Associate Professor

Member of:


    1. 1993
    2. Published

      Flow cytometric measurement of RNA synthesis based on bromouridine labelling and combined with measurement of DNA content or cell surface antigen

      Jensen, Peter Østrup, Larsen, J. & Larsen, J. K., 1993, In: Acta Oncologica. 32, 5, p. 521-4 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    3. Published

      Flow cytometric measurement of RNA synthesis using bromouridine labelling and bromodeoxyuridine antibodies

      Jensen, Peter Østrup, Larsen, J., Christiansen, J. & Larsen, J. K., 1993, In: Cytometry. 14, 4, p. 455-8 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    4. 1994
    5. Published

      Discrimination of bromodeoxyuridine labelled and unlabelled mitotic cells in flow cytometric bromodeoxyuridine/DNA analysis

      Jensen, Peter Østrup, Larsen, J. K., Christensen, I. J. & van Erp, P. E., 1 Feb 1994, In: Cytometry. 15, 2, p. 154-61 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    6. Published

      Tumor-promoting phorbol ester transiently down-modulates the p53 level and blocks the cell cycle

      Skouv, J., Jensen, Peter Østrup, Forchhammer, J., Larsen, J. K. & Lund, L. R., Mar 1994, In: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 5, 3, p. 329-40 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    7. 1995
    8. Published

      Permeability of commercial solvents through living human skin

      Ursin, C., Hansen, C. M., Van Dyk, J. W., Jensen, Peter Østrup, Christensen, I. J. & Ebbehoej, J., Jul 1995, In: Journal of Occupational and Environmental Hygiene. 56, 7, p. 651-60 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    9. 1998
    10. Published

      Immediate bromodeoxyuridine labelling of unseparated human bone marrow cells ex vivo is superior to labelling after routine laboratory processing

      Jensen, Peter Østrup, Mortensen, B. T., Christensen, I. J. & Larsen, J. K., Feb 1998, In: Cell Proliferation. 31, 1, p. 1-7 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    11. Published

      Changing bone marrow micro-environment during development of acute myeloid leukaemia in rats

      Mortensen, B. T., Jensen, Peter Østrup, Helledie, N., Iversen, P. O., Ralfkiaer, E., Larsen, J. K. & Madsen, M. T., Jul 1998, In: British Journal of Haematology. 102, 2, p. 458-64 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    12. Published

      S-phase induction by interleukin-6 followed by chemotherapy in patients with refractory multiple myeloma

      de Nully Brown, P., Jensen, Peter Østrup, Diamant, M., Mortensen, B. T., Hovgaard, D., Gimsing, P. & Nissen, N. I., Nov 1998, In: Leukemia Research. 22, 11, p. 983-9 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    13. 1999
    14. Published

      S-phase induction by interleukin-6 followed by chemotherapy in patients with chronic lymphocytic leukemia and non-Hodgkin's lymphoma

      Brown, Peter de Nully, Diamant, M., Jensen, Peter Østrup, Geisler, C. H., Mortensen, B. T. & Nissen, N. I., Jul 1999, In: Leukemia and Lymphoma. 34, 3-4, p. 325-33 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    15. 2000
    16. Published

      Increased cellular hypoxia and reduced proliferation of both normal and leukaemic cells during progression of acute myeloid leukaemia in rats

      Jensen, Peter Østrup, Mortensen, B. T., Hodgkiss, R. J., Iversen, P. O., Christensen, I. J., Helledie, N. & Larsen, J. K., Dec 2000, In: Cell Proliferation. 33, 6, p. 381-95 15 p.

      Research output: Contribution to journalJournal articlepeer-review

    17. 2001
    18. Published

      Analysis of RNA synthesis by cytometry

      Jensen, Peter Østrup, Larsen, J. & Larsen, J. K., 2001, Analysis of RNA synthesis by cytometry. Vol. 64. p. 129-38 10 p. (Methods in Cell Biology).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    19. Published

      Flow cytometric analysis of RNA synthesis by detection of bromouridine incorporation

      Larsen, J. K., Jensen, Peter Østrup & Larsen, J., 2001, In: Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.]. Chapter 7, p. Unit 7.12

      Research output: Contribution to journalJournal articlepeer-review

    20. 2002
    21. Published

      Selective recruitment of Th I cells induced by re-infection of succeptible and resistant mice with Pseudomonas aerugionosa in the lungs indicates protective role of IL-12.

      Moser, Claus Ernst, Jensen, Peter Østrup, Kobayashi, O., Hougen, H. P., Song, Z., Rygaard, J., Kharazmi, A. & Høiby, Niels, 2002, In: Clinical and Experimental Immunology. 127, 2, p. 206-213 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    22. 2003
    23. Published

      A highly selective CCR2 chemokine agonist encoded by human herpesvirus 6

      Lüttichau, H. R., Clark-Lewis, I., Jensen, Peter Østrup, Moser, C., Gerstoft, Jan & Schwartz, Thue W., 2003, In: Journal of Biological Chemistry. 278, Vol. 278 (13), p. 10928-33 5 p.

      Research output: Contribution to journalJournal articlepeer-review

    24. Published

      Cytokine and surface receptor diversity of NK cells in resistant C3H/HeN and susceptible BALB/c mice with chronic Pseudomonas aeruginosa lung infection

      Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Shirai, R. & Høiby, Niels, Sep 2003, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 111, 9, p. 891-7 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    25. 2004
    26. Published

      Faster activation of polymorphonuclear neutrophils in resistant mice during early innate response to Pseudomonas aeruginosa lung infection

      Jensen, Peter Østrup, Moser, Claus Ernst, Kobayashi, O., Hougen, H. P., Kharazmi, A. & Høiby, Niels, 2004, In: Clinical and Experimental Immunology. 137, 3, p. 478-485 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    27. Published

      High resolution DNA flow cytometry of boar sperm cells in identification of boars carrying cytogenetic aberrations

      Larsen, Jacob, Christensen, K., Larsen, J. K., Jensen, Peter Østrup, Gustavsson, I. & Christensen, I. J., Aug 2004, In: Theriogenology. 62, 3-4, p. 501-11 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    28. 2005
    29. Published

      Identity and effects of quorum-sensing inhibitors produced by Penicillium species

      Rasmussen, T. B., Skindersoe, M. E., Bjarnsholt, T., Phipps, R. K., Christensen, K. B., Jensen, Peter Østrup, Andersen, Jens Bo, Koch, B., Larsen, T. O., Hentzer, M., Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: Microbiology. 151, Pt 5, p. 1325-40 15 p.

      Research output: Contribution to journalJournal articlepeer-review

    30. Published

      Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis

      Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, 2005, In: Infection and Immunity. 73, 4, p. 2504-14 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    31. Published

      Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Burmølle, Mette, Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, Claus Ernst, Molin, S., Høiby, Niels & Givskov, Michael, Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.

      Research output: Contribution to journalJournal articlepeer-review

    32. Published

      Serum concentrations of GM-CSF and G-CSF correlate with the Th1/Th2 cytokine response in cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

      Moser, Claus Ernst, Jensen, Peter Østrup, Pressler, T., Frederiksen, B., Lanng, S., Kharazmi, A., Koch, C. & Høiby, Niels, Jun 2005, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 113, 6, p. 400-9 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    33. Published

      Erratum: Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis (Infection and Immunity (2005) 73, 4 (2504-2514))

      Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, Aug 2005, In: Infection and Immunity. 73, 8, p. 5290 1 p.

      Research output: Contribution to journalComment/debatepeer-review

    34. 2006
    35. Published

      Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils

      Fexby, S., Bjarnsholt, Thomas, Jensen, Peter Østrup, Roos, V., Høiby, Niels, Givskov, Michael & Klemm, P., 2006, In: Infection and Immunity. 75, 1, p. 30-4 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    36. Published

      Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia

      Jensen, Peter Østrup, Moser, Claus Ernst, Kharazmi, A., Presler, T., Koch, C. & Høiby, Niels, Aug 2006, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 5, 3, p. 145-51 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    37. 2007
    38. Published

      Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.

      Høiby, Niels, Johansen, Helle Krogh, Ciofu, Oana, Jensen, Peter Østrup, Bjarnsholt, Thomas & Givskov, Michael, 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.

      Research output: Contribution to journalJournal articlepeer-review

    39. Published

      Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model

      Hultqvist, Louise Dahl, Moser, C., Jensen, Peter Østrup, Rasmussen, T. B., Christophersen, L., Kjelleberg, S., Kumar, N., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2007, In: Microbiology. 153, Pt 7, p. 2312-20 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    40. Published

      Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa

      Jensen, Peter Østrup, Bjarnsholt, Thomas, Phipps, R., Rasmussen, T. B., Calum, H., Christoffersen, L., Moser, C., Williams, P., Pressler, T., Givskov, Michael & Høiby, Niels, 2007, In: Microbiology. 153, Pt 5, p. 1329-38 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    41. Published

      Silver against Pseudomonas aeruginosa biofilms

      Bjarnsholt, Thomas, Kirketerp-Møller, K., Kristiansen, S., Phipps, R., Nielsen, A. K., Jensen, Peter Østrup, Høiby, Niels & Givskov, Michael, 2007, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 115, 8, p. 921-8 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    42. 2008
    43. Published

      Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection

      Bohn, Y. T., Brandes, G., Rakhimova, E., Horatzek, S., Salunkhe, P., Munder, A., van Barneveld, A., Jordan, D., Bredenbruch, F., Häussler, S., Riedel, K., Eberl, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, C., Høiby, Niels, Tümmler, B. & Wiehlmann, L., 2008, In: Molecular Microbiology. 71, 3, p. 730-47 17 p.

      Research output: Contribution to journalJournal articlepeer-review

    44. Published

      Thermal injury induces impaired function in polymorphonuclear neutrophil granulocytes and reduced control of burn wound infection

      Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Christoffersen, L., Damlund, D. S. M., Alhede, M., Bjarnsholt, Thomas, Hougen, H. P., Givskov, Michael, Jacobsen, G. K. & Høiby, Niels, 2008, In: Clinical and Experimental Immunology. 156, 1, p. 102-110 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    45. Published

      Why chronic wounds will not heal: a novel hypothesis

      Bjarnsholt, Thomas, Kirketerp-Møller, K., Jensen, Peter Østrup, Madsen, K. G., Phipps, R. K., Krogfelt, K., Høiby, Niels & Givskov, Michael, 2008, In: Wound Repair and Regeneration. 16, 1, p. 2-10 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    46. Published

      Distribution, organization, and ecology of bacteria in chronic wounds

      Kirketerp-Møller, K., Jensen, Peter Østrup, Fazli, M., Madsen, K. G., Pedersen, J., Moser, C., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Aug 2008, In: Journal of Clinical Microbiology. 46, 8, p. 2717-22 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    47. 2009
    48. Published

      Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes

      Alhede, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Phipps, R. K., Moser, Claus Ernst, Christophersen, L., Hultqvist, Louise Dahl, van Gennip, M., Parsek, M., Høiby, Niels, Rasmussen, T. B. & Givskov, Michael, 2009, In: Microbiology. 155, 11, p. 3500-3508 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    49. Published

      Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis

      Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    50. Published

      Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Fiandaca, M. J., Pedersen, J., Hansen, C. R., Andersen, C. B., Pressler, T., Givskov, Michael & Høiby, Niels, 1 Jun 2009, In: Pediatric Pulmonology. 44, 6, p. 547-58 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    51. Published

      Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes

      Van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Phipps, R., Jensen, Peter Østrup, Christophersen, L., Pamp, S. J., Moser, C., Mikkelsen, P. J., Koh, A. Y., Tolker-Nielsen, Tim, Pier, G. B., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Jul 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 7, p. 537-46 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    52. Published

      Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa

      van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, H. P., Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    53. 2010
    54. Published

      Adaptive Immune Responses and Biofilm Infections

      Moser, Claus Ernst & Jensen, Peter Østrup, 2010, Biofilm Infections. Bjarnsholt, T., Moser, C. E., Jensen, P. Ø. & Høiby, N. (eds.). 1st ed. New York. NY. US, p. 201-214 14 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    55. Published

      An in vitro model of bacterial infections in wounds and other soft tissues

      Werthén, M., Henriksson, L., Jensen, Peter Østrup, Sternberg, C., Givskov, Michael & Bjarnsholt, Thomas, 2010, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 118, 2, p. 156-64 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    56. Published

      Biofilm Infections

      Bjarnsholt, Thomas (ed.), Moser, Claus Ernst (ed.), Jensen, Peter Østrup (ed.) & Høiby, Niels (ed.), 2010, Springer Publishing Company. 350 p.

      Research output: Book/ReportBookpeer-review

    57. Published

      Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

      Burmølle, Mette, Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.

      Research output: Contribution to journalReviewpeer-review

    58. Published

      Complete genomic sequence of the CF pathogene Achromobacter xylosoxidans and in vitro biofilm formation

      Jakobsen, T. H., Hansen, M., Kerpedjiev, P., Hansen, L., Jensen, Peter Østrup, Hansen, C. R., Qvortrup, K., Givskov, M., Burmølle, M., Sørensen, S. J., Høiby, Niels & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conferencePaperResearchpeer-review

    59. Published

      In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect

      Bjarnsholt, Thomas, van Gennip, M., Jakobsen, Tim Holm, Hultqvist, Louise Dahl, Jensen, Peter Østrup & Givskov, Michael, 2010, In: Nature Protocols (Print Edition). 5, 2, p. 282-93 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    60. Published

      Increased severity of chronic Pseudomonas aeruginosa biofilm infection in the smaller airways of BALB/c mice

      Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    61. Published

      Increased severity of chronic Pseuomonas aeruginosa biofilm infection in the smaller airways of BALB/C mice

      Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 0 p.

      Research output: Contribution to conferencePosterResearchpeer-review

    62. Published

      Innate Immune Response to Infectious Biofilms

      Jensen, Peter Østrup & Moser, Claus Ernst, 2010, Biofilm Infections. Bjarnsholt, T., Moser, C. E., Jensen, P. Ø. & Høiby, N. (eds.). 1st ed. New York, NY, US, p. 185-200 16 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    63. Published

      Nitric oxide production by polymorphonuclear leukocytes in sputum from CF patients with chronic lung infection

      Jensen, Peter Østrup, Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Pressler, T. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    64. Published

      Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection

      Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Kühl, M., Høiby, Niels & Jensen, Peter Østrup, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    65. Published

      Phenotype of non-attached Pseudomonas aeruginosa microclonies resembles attached biofilm, including reversible antibiotic tolerance

      Alhede, M., Qvortrup, K., Allesen-Holm, M., van Gennip, M., Christensen, L., Jensen, Peter Østrup, Nielsen, A., Tolker-Nielsen, T., Høiby, Niels, Givskov, M. C. & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    66. Published

      Pseudomonas aeruginosa biofilm infection in the smaller airways of BALB/c mice exacerbates pulmonary inflammation.

      Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 1 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    67. Published

      Summary and Perspectives

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, 2010, Biofilm Infections. Bjarnsholt, T., Moser, C. E., Jensen, P. Ø. & Høiby, N. (eds.). 1st ed. New York. NY. US: Springer Science+Business Media, p. 291-293 3 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    68. Published

      The immune system vs. Pseudomonas aeruginosa biofilms

      Jensen, Peter Østrup, Givskov, Michael, Bjarnsholt, Thomas & Moser, C., 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 292-305 14 p.

      Research output: Contribution to journalJournal articlepeer-review

    69. Published

      Visualization of in vivo biofilm developing on silicone implants and the interaction with the cellular response

      van Gennip, M., Christensen, L., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    70. Published

      Visualization of the in vivo interaction of a P. aeruginosa biofilm & the innate host cellular response

      van Gennip, M., Christensen, L. D., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    71. Published

      Inflammation in Achromobacter xylosoxidans infected cystic fibrosis patients

      Hansen, C. R., Pressler, T., Nielsen, K. G., Jensen, Peter Østrup, Bjarnsholt, Thomas & Høiby, Niels, 1 Jan 2010, In: Journal of Cystic Fibrosis. 9, 1, p. 51-58 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    72. Published

      Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

      Kolpen, Mette, Hansen, C. R., Bjarnsholt, Thomas, Moser, C., Hultqvist, Louise Dahl, van Gennip, M., Ciofu, Oana, Mandsberg, L., Kharazmi, A., Döring, G., Givskov, Michael, Høiby, Niels & Jensen, Peter Østrup, 1 Jan 2010, In: Thorax. 65, 1, p. 57-62 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    73. Published

      Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Jakobsen, Tim Holm, Phipps, R., Nielsen, A. K., Rybtke, Morten Levin, Tolker-Nielsen, Tim, Givskov, Michael, Høiby, Niels, Ciofu, Oana & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 1 Jan 2010, In: PLoS ONE. 5, 4, p. e10115

      Research output: Contribution to journalJournal articlepeer-review

    74. Published

      Upregulation of dendritic cells during chronic Pseudomonas aeruginosa lung infection in BALB/c mice

      Damlund, D. S. M., Jensen, Peter Østrup, Christophersen, L. J., Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    75. Published

      Relative contribution of Prevotella intermedia and Pseudomonas aeruginosa to lung pathology in airways of patients with cystic fibrosis

      Ulrich, M., Beer, I., Braitmaier, P., Dierkes, M., Kummer, F., Krismer, B., Schumacher, U., Gräpler-Mainka, U., Riethmüller, J., Jensen, Peter Østrup, Bjarnsholt, Thomas, Høiby, Niels, Bellon, G. & Döring, G., 1 Nov 2010, In: Thorax. 65, 11, p. 978-984 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    76. 2011
    77. Published

      Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients

      Høiby, Niels, Johansen, Helle Krogh, Moser, Claus Ernst, Ciofu, Oana, Jensen, Peter Østrup, Kolpen, Mette, Mandsberg, L., Givskov, Michael, Molin, S. & Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer, p. 167-184 18 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    78. Published

      Biofilm infections

      Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup & Høiby, Niels, 2011, Springer New York. 314 p.

      Research output: Book/ReportBookpeer-review

    79. Published

      Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis

      Aanæs, Kasper, Rickelt, L. F., Johansen, Helle Krogh, von Buchwald, Christian, Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2011, In: Journal of Cystic Fibrosis. 10, 2, p. 114-120 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    80. Published

      Lactate in cystic fibrosis sputum

      Bensel, T., Stotz, M., Borneff-Lipp, M., Wollschläger, B., Wienke, A., Taccetti, G., Campana, S., Meyer, K. C., Jensen, Peter Østrup, Lechner, U., Ulrich, M., Döring, G. & Worlitzsch, D., 2011, In: Journal of Cystic Fibrosis. 10, 1, p. 37-44 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    81. Published

      Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm

      Alhede, M., Kragh, K. N., Qvortrup, Klaus, Allesen-Holm, M., van Gennip, M., Hultqvist, Louise Dahl, Jensen, Peter Østrup, Nielsen, A. K., Parsek, M., Wozniak, D., Molin, S., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2011, In: P L o S One. 6, 11, p. e27943

      Research output: Contribution to journalJournal articlepeer-review

    82. Published

      Report from Eurobiofilms 2011

      Jensen, Peter Østrup & Tolker-Nielsen, Tim, 2011, In: Future Microbiology. 6, 11, p. 1237-45

      Research output: Contribution to journalJournal articlepeer-review

    83. Published

      Summary and perspectives

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, 2011, Biofilm Infections. Springer New York, p. 291-294 4 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    84. Published

      The clinical impact of bacterial biofilms

      Høiby, Niels, Ciofu, Oana, Johansen, Helle Krogh, Song, Z., Moser, Claus Ernst, Jensen, Peter Østrup, Molin, S., Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: International Journal of Oral Science. 3, 2, p. 55-65

      Research output: Contribution to journalJournal articlepeer-review

    85. Published

      The implication of Pseudomonas aeruginosa biofilms in infections

      Rybtke, Morten Levin, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: Inflammation & Allergy - Drug Targets. 10, 2, p. 141-57 17 p.

      Research output: Contribution to journalJournal articlepeer-review

    86. 2012
    87. Published

      Bead-size directed distribution of Pseudomonas aeruginosa results in distinct inflammatory response in a mouse model of chronic lung infection

      Christophersen, L. J., Trøstrup, H., Damlund, D. S. M., Bjarnsholt, Thomas, Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, 2012, In: Experimental and clinical endocrinology. 170, 2, p. 222-30 10 p., 170.

      Research output: Contribution to journalJournal articlepeer-review

    88. Published

      Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs

      Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.

      Research output: Contribution to journalJournal articlepeer-review

    89. Published

      Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing

      Jakobsen, Tim Holm, van Gennip, M., Phipps, R. K., Shanmugham, M. S., Hultqvist, Louise Dahl, Alhede, M., Skindersoe, M. E., Rasmussen, T. B., Friedrich, K., Uthe, F., Jensen, Peter Østrup, Moser, Claus Ernst, Nielsen, Kristian Fog, Eberl, L., Larsen, T. O., Tanner, D. A., Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., May 2012, In: Antimicrobial Agents and Chemotherapy. 56, 5, p. 2314-25 12 p.

      Research output: Contribution to journalJournal articlepeer-review

    90. Published

      Process for the manufacture of ajoene derivatives

      Bjarnsholt, Thomas, Høiby, Niels, Jensen, Peter Østrup, Phipps, R., Shanmugham, Meenakshi, S., Alhede, M., Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Tanner, D., Larsen, Thomas, O. & Givskov, Michael, 14 Jun 2012, IPC No. C07C 323/ 65 A I, Patent No. WO2012076016, Priority date 8 Dec 2010, Priority No. EP20100194154

      Research output: Patent

    91. Published

      Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo

      van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Qvortrup, Klaus, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    92. Published

      Genetical analysis of all Danish patients diagnosed with chronic granulomatous disease

      Jakobsen, M. A., Katzenstein, T. L., Valerius, N. H., Roos, D., Fisker, N., Mogensen, T. H., Jensen, Peter Østrup & Barington, T., Nov 2012, In: Scandinavian Journal of Immunology. 76, 5, p. 505-11 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    93. 2013
    94. Published

      Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes

      Jakobsen, T. H., Hansen, M. A., Jensen, P. Ø., Hansen, L., Riber, L., Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, K., Burmølle, M., Moser, C. E., Kühl, M., Ciofu, O., Givskov, M., Sørensen, S. J. & 2 others, Høiby, Niels & Bjarnsholt, Thomas, 2013, In: P L o S One. 8, 7, 17 p., e68484.

      Research output: Contribution to journalJournal articlepeer-review

    95. Published

      The in vivo biofilm

      Bjarnsholt, Thomas, Alhede, M., Alhede, M., Eickhardt-Sørensen, S. R., Moser, Claus Ernst, Kühl, Michael, Jensen, Peter Østrup & Høiby, Niels, 2013, In: Trends in Microbiology. 21, 9, p. 466-474 9 p.

      Research output: Contribution to journalReviewpeer-review

    96. Published

      Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model

      Trøstrup, H., Thomsen, K., Christophersen, L. J., Hougen, H. P., Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    97. Published

      Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms

      Chiang, W., Nilsson, M., Jensen, Peter Østrup, Høiby, Niels, Nielsen, T., Givskov, Michael & Tolker-Nielsen, Tim, May 2013, In: Antimicrobial Agents and Chemotherapy. 57, 5, p. 2352-61 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    98. Published

      Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors

      Jakobsen, Tim Holm, Bjarnsholt, Thomas, Jensen, Peter Østrup, Givskov, Michael & Høiby, Niels, Jul 2013, In: Future Microbiology. 8, 7, p. 901-21 21 p.

      Research output: Contribution to journalJournal articlepeer-review

    99. Published

      Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model

      Cavanagh, J. P., Granslo, H. N., Fredheim, E. A., Christophersen, L., Jensen, Peter Østrup, Thomsen, K., van Gennip, M., Klingenberg, C., Flaegstad, T., Moser, Claus Ernst & Alhede, M., Sep 2013, In: The Journal of antimicrobial chemotherapy. 68, 9, p. 2106-10 5 p.

      Research output: Contribution to journalJournal articlepeer-review

    100. Published

      Sublethal ciprofloxacin treatment leads to rapid development of high-level ciprofloxacin resistance during long-term experimental evolution of Pseudomonas aeruginosa

      Jørgensen, K. M., Wassermann, T., Jensen, Peter Østrup, Hengzuang, W., Molin, S., Høiby, Niels & Ciofu, Oana, Sep 2013, In: Antimicrobial Agents and Chemotherapy. 57, 9, p. 4215-21 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    101. 2014
    102. Published

      Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation

      Brochmann, R. P., Toft, A., Ciofu, Oana, Briales, A., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, 2014, In: International Journal of Antimicrobial Agents. 43, 2, p. 140-147 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    103. Published

      Exhaled breath analysis using electronic nose in cystic fibrosis and primary ciliary dyskinesia patients with chronic pulmonary infections

      Joensen, O., Paff, T., Haarman, E. G., Skovgaard, I. M., Jensen, Peter Østrup, Bjarnsholt, Thomas & Nielsen, Kim G., 2014, In: PLOS ONE. 9, 12, p. 1-15 15 p., e115584.

      Research output: Contribution to journalJournal articlepeer-review

    104. Published

      Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms

      Jensen, Peter Østrup, Briales, A., Brochmann, R. P., Wang, H., Kragh, K. N., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Ciofu, Oana, 2014, In: Pathogens and Disease. 70, 3, p. 440-443 4 p.

      Research output: Contribution to journalJournal articlepeer-review

    105. Published

      Nitric oxide production by polymorphonuclear leukocytes in infected cystic fibrosis sputum consumes oxygen

      Kolpen, Mette, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Rickelt, L. F., Kühl, Michael, Hempel, C., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Clinical and Experimental Immunology. 177, 1, p. 310–319 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    106. Published

      Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

      Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: PLOS ONE. 9, 1, p. e84353 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    107. Published

      Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum

      Line, L., Alhede, M., Kolpen, Mette, Kühl, Michael, Ciofu, Oana, Bjarnsholt, Thomas, Moser, Claus Ernst, Toyofuku, M., Nomura, N., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Frontiers in Microbiology. 5, 11 p., 554.

      Research output: Contribution to journalJournal articlepeer-review

    108. Published

      Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients

      Kragh, K. N., Alhede, M., Jensen, Peter Østrup, Moser, Claus Ernst, Scheike, Thomas, Jacobsen, C. S., Poulsen, Steen Seier, Eickhardt-Sørensen, S. R., Trostrup, H., Christoffersen, L., Hougen, H. P., Rickelt, L. F., Kühl, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2014, In: Infection and Immunity. 82, 11, p. 4477-4486 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    109. Published

      Plasmodium falciparum avoids change in erythrocytic surface expression of phagocytosis markers during inhibition of nitric oxide synthase activity

      Hempel, C., Kohnke, H., Maretty, L., Jensen, Peter Østrup, Staalsø, Trine & Kurtzhals, Jørgen, Nov 2014, In: Molecular and Biochemical Parasitology. 198, 1, p. 29-36 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    110. 2015
    111. Published

      Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model

      Cao, B., Christophersen, L., Thomsen, K., Sønderholm, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2015, In: The Journal of antimicrobial chemotherapy. 70, 7, p. 2057-2063 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    112. Published

      Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

      Ciofu, Oana, Tolker-Nielsen, Tim, Jensen, Peter Østrup, Wang, H. & Høiby, Niels, 2015, In: Advanced Drug Delivery Reviews. 85, p. 7-23 17 p.

      Research output: Contribution to journalReviewpeer-review

    113. Published

      Denitrification by cystic fibrosis pathogens - Stenotrophomonas maltophilia is dormant in sputum

      Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas, Line, L., Hansen, C. R., Dalbøge, C. S., Hansen, N., Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2015, In: International Journal of Medical Microbiology. 305, 1, p. 1-10 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    114. Published

      The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

      Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    115. Published

      Antibiofilm Properties of Acetic Acid

      Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

      Research output: Contribution to journalJournal articlepeer-review

    116. Published

      Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    117. Published

      Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Trøstrup, H., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Bundgaard, H., Høiby, Niels & Moser, C., 1 Dec 2015, In: European Journal of Clinical Microbiology & Infectious Diseases. 34, 12, p. 2349-2357 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    118. 2016
    119. Published

      Development of a rechargeable optical hydrogen peroxide sensor - sensor design and biological application

      Koren, K., Jensen, Peter Østrup & Kühl, Michael, 2016, In: Analyst. 141, 14, p. 4332-4339 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    120. Published

      Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment

      Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.

      Research output: Contribution to journalLetterpeer-review

    121. Published

      Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

      Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.

      Research output: Contribution to journalJournal articlepeer-review

    122. Published

      Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.

      Research output: Contribution to journalJournal articlepeer-review

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