Thomas Bjarnsholt

Thomas Bjarnsholt

Professor


  1. 2021
  2. Published

    The impact of mental models on the treatment and research of chronic infections due to biofilms

    Bjarnsholt, Thomas, Mastroianni, E., Kirketerp-Møller, K., Stewart, P. S., Mähr, A. M., Domínguez Cabañes, A. & Nørager, R., 2021, In: APMIS. 129, 10, p. 598-606

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of antimicrobial solutions and wound dressings

    Chen, X., Lorenzen, J., Xu, Y., Jonikaite, M., Thaarup, Ida Clement, Bjarnsholt, Thomas, Kirketerp-Møller, K. & Thomsen, T. R., 2021, In: Wound Repair and Regeneration. 29, 5, p. 820-829

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Catalase protects biofilm of Staphylococcus aureus against daptomycin activity

    El Haj, C., Lichtenberg, Mads, Nielsen, K. L., Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: Antibiotics. 10, 5, 511.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Dynamics of skin microbiota in shoulder surgery infections

    Fatima, N., Bjarnsholt, Thomas & Bay, Lene, 2021, In: APMIS. 129, 12, p. 665-674

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Sampling challenges in diagnosis of chronic bacterial infections

    Jakobsen, Tim Holm, Xu, Y., Bay, Lene, Schønheyder, H. C., Jakobsen, T., Bjarnsholt, Thomas & Thomsen, T. R., 2021, In: Journal of Medical Microbiology. 70, 3

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Biofilm and equine limb wounds

    Jørgensen, Elin , Bjarnsholt, Thomas & Jacobsen, Stine, 2021, In: Animals. 11, 10, 2825.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa

    Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The discovery of bacterial biofilm in patients with muscle invasive bladder cancer

    Nadler, N., Kvich, Lasse Andersson, Bjarnsholt, Thomas, Jensen, J. B., Gögenur, Ismail & Azawi, Nessn H., 2021, In: APMIS. 129, 5, p. 265-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Peptidoglycan-Binding Anchor Is a Pseudomonas aeruginosa OmpA Family Lipoprotein With Importance for Outer Membrane Vesicles, Biofilms, and the Periplasmic Shape

    Paulsson, M., Kragh, K. N., Su, Y. C., Sandblad, L., Singh, B., Bjarnsholt, Thomas & Riesbeck, K., 2021, In: Frontiers in Microbiology. 12, 639582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Biofilm Research in Bovine Mastitis

    Pedersen, Regitze Renee, Krömker, Volker, Bjarnsholt, Thomas, Dahl-Pedersen, Kirstin, Buhl, Rikke & Jørgensen, Elin , 2021, In: Frontiers in Veterinary Science. 8, 11 p., 656810.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Delayed neutrophil recruitment allows nascent Staphylococcus aureus biofilm formation and immune evasion

    Pettygrove, B. A., Kratofil, R. M., Alhede, M., Jensen, Peter Østrup, Newton, M., Qvortrup, Klaus, Pallister, K. B., Bjarnsholt, Thomas, Kubes, P., Voyich, J. M. & Stewart, P. S., Aug 2021, In: Biomaterials. 275, 13 p., 120775.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Biofilms can act as plasmid reserves in the absence of plasmid specific selection

    Røder, Henriette Lyng, Trivedi, Urvish, Russel, J., Kragh, K. N., Herschend, J., Thalsø-Madsen, I., Tolker-Nielsen, Tim, Bjarnsholt, Thomas, Burmølle, Mette & Madsen, Jonas Stenløkke, 2021, In: npj Biofilms and Microbiomes. 7, 6 p., 78.

    Research output: Contribution to journalLetterResearchpeer-review

  14. Published

    Current in vitro biofilm-infected chronic wound models for developing new treatment possibilities

    Thaarup, Ida Clement & Bjarnsholt, Thomas, 2021, In: Advances in Wound Care. 10, 2, p. 91-102 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Measuring enzymatic degradation of degradable starch microspheres using confocal laser scanning microscopy

    Thaarup, Ida Clement, Gummesson, C. & Bjarnsholt, Thomas, 2021, In: Acta Biomaterialia. 131, p. 464-471

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2020
  17. Published

    Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes

    Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, Lene & Bjarnsholt, Thomas, 2020, In: Medical Microbiology and Immunology. 209, p. 669–680

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The origin of extracellular DNA in bacterial biofilm infections in vivo

    Alhede, M., Alhede, M., Qvortrup, Klaus, Kragh, K. N., Jensen, Peter Østrup, Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Pathogens and Disease. ftaa018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Minimum information guideline for spectrophotometric and fluorometric methods to assess biofilm formation in microplates

    Allkja, J., Bjarnsholt, Thomas, Coenye, T., Cos, P., Fallarero, A., Harrison, J. J., Lopes, S. P., Oliver, A., Pereira, M. O., Ramage, G., Shirtliff, M. E., Stoodley, P., Webb, J. S., Zaat, S. A. J., Goeres, D. M. & Azevedo, N. F., 2020, In: Biofilm. 2, 8 p., 100010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Universal Dermal Microbiome in Human Skin

    Bay, Lene, Barnes, Christopher James, Fritz, Blaine Gabriel, Thorsen, Jonathan Jan Ilve, Restrup, M. E. M., Rasmussen, Linett, Sørensen, J. K., Hesselvig, A. B., Odgaard, Anders, Hansen, Anders Johannes & Bjarnsholt, Thomas, 2020, In: mBio. 11, 1, 13 p., e02945-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Pathological and microbiological impact of a gentamicin-loaded biocomposite following limited or extensive debridement in a porcine model of osteomyelitis

    Blirup-Plum, Sophie Amalie, Bjarnsholt, Thomas, Jensen, Henrik Elvang, Kragh, K. N., Aalbæk, Bent, Gottlieb, Hans, Bue, M. & Jensen, Louise Kruse, 2020, In: Bone and Joint Research. 9, 7, p. 394-401 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology

    Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Copper-Silver alloy coated door handles as a potential antibacterial strategy in clinical settings

    Ciacotich, N., Kvich, Lasse Andersson, Sanford, N., Wolcott, J., Bjarnsholt, Thomas & Gram, L., 2020, In: Coatings. 10, 8, 9 p., 790.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The future of biofilm research – Report on the ‘2019 Biofilm Bash’

    Coenye, T., Kjellerup, B., Stoodley, P. & Bjarnsholt, Thomas, 2020, In: Biofilm. 2, 9 p., 100012.

    Research output: Contribution to journalComment/debateResearchpeer-review

  25. Published

    The environmental occurrence of Pseudomonas aeruginosa

    Crone, S., Vives-Flórez, M., Kvich, Lasse Andersson, Saunders, A. M., Malone, M., Nicolaisen, Mette Haubjerg, Martínez-García, E., Rojas-Acosta, C., Catalina Gomez-Puerto, M., Calum, Henrik Pierre, Whiteley, M., Kolter, R. & Bjarnsholt, Thomas, 2020, In: APMIS. 128, 3, p. 220-231

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Does an Antimicrobial Incision Drape Prevent Intraoperative Contamination? A Randomized Controlled Trial of 1187 Patients

    Hesselvig, A. B., Arpi, M., Madsen, F., Bjarnsholt, Thomas, Odgaard, Anders & ICON Study Group, I. S. G., 2020, In: Clinical Orthopaedics and Related Research. 478, 5, p. 1007-1015

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Histologic changes and gene expression patterns in biopsy specimens from bacteria-inoculated and noninoculated excisional body and limb wounds in horses healing by second intention

    Jørgensen, Elin , Hjerpe, F. B., Hougen, H. P., Bjarnsholt, Thomas, Berg, Lise Charlotte & Jacobsen, Stine, 2020, In: American Journal of Veterinary Research. 81, 3, p. 276-284 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Staphylococcus aureus augments release of matrix metalloproteinase-8 from human polymorphonuclear leukocytes

    Kirketerp-Møller, K., Bjarnsholt, Thomas, Jensen, Peter Østrup & Ågren, Magnus, 2020, In: Acta Dermato-Venereologica. 100, 15, p. 1-2 2 p., adv00232.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The zone model: A conceptual model for understanding the microenvironment of chronic wound infection

    Kirketerp-Møller, K., Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Wound Repair and Regeneration. 28, 5, p. 593-599

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Eradication of biofilms on tympanostomy tubes with acetic acid treatment: an in vitro study

    Kjeldsen, M., Homøe, Preben, Nielsen, Anne Kirstine, Crone, S., Nørskov Kragh, K. & Bjarnsholt, Thomas, 2020, In: APMIS. 128, 6, p. 445-450

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

    Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Do Mixed-Species Biofilms Dominate in Chronic Infections? Need for in situ Visualization of Bacterial Organization

    Kvich, Lasse Andersson, Burmølle, Mette, Bjarnsholt, Thomas & Lichtenberg, Mads, 2020, In: Frontiers in Cellular and Infection Microbiology. 10, 12 p., 396.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Predictive Metagenomic Analysis Reveals a Role of Cutaneous Dysbiosis in the Development of Hidradenitis Suppurativa

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Jørgensen, A. H., Bay, Lene, Bjarnsholt, Thomas, Fuursted, K., Thomsen, Simon Francis & Jemec, Gregor, 2020, In: Journal of Investigative Dermatology. 140, 7, p. 1473-1476

    Research output: Contribution to journalLetterResearchpeer-review

  34. Published

    The efficacy of topical agents used in wounds for managing chronic biofilm infections: A systematic review

    Schwarzer, S., James, G. A., Goeres, D., Bjarnsholt, Thomas, Vickery, K., Percival, S. L., Stoodley, P., Schultz, G., Jensen, S. O. & Malone, M., 2020, In: Journal of Infection. 80, 3, p. 261-270

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Risk factors for chronic biofilm-related infection associated with implanted medical devices

    Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Clinical Microbiology and Infection. 26, 8, p. 1034-1038

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    Antibiotic susceptibility of cystic fibrosis lung microbiome members in a multispecies biofilm

    Vandeplassche, E., Sass, A., Ostyn, L., Burmølle, Mette, Kragh, K. N., Bjarnsholt, Thomas, Coenye, T. & Crabbé, A., 2020, In: Biofilm. 2, 9 p., 100031.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Pathogenic CD8+ epidermis-resident memory T cells displace dendritic epidermal T cells in allergic dermatitis

    Gadsbøll, Anne-Sofie Østergaard, Jee, Mia Hamilton, Funch, Anders Boutrup, Alhede, M., Mraz, Veronika, Weber, Julie Friis, Callender, L. A., Carroll, E. C., Bjarnsholt, Thomas, Woetmann, Anders , Ødum, Niels, Thomsen, Allan Randrup, Johansen, Jeanne Duus, Henson, S. M., Geisler, Carsten & Bonefeld, Charlotte Menne, 2020, In: The Journal of Investigative Dermatology. 140, 4, p. 806-815.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2019
  39. Published

    Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction

    Bjarnsholt, Thomas, Jensen, Peter Østrup & Alhede, M., 2019, In: Pathogens and Disease. 77, 5, ftz052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    In Situ Monitoring of the Antibacterial Activity of a Copper-Silver Alloy Using Confocal Laser Scanning Microscopy and pH Microsensors

    Ciacotich, N., Kragh, K. N., Lichtenberg, Mads, Tesdorpf, J. E., Bjarnsholt, Thomas & Gram, L., 2019, In: Global Challenges. 3, 11, 9 p., 1900044.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms

    Crabbé, A., Jensen, Peter Østrup, Bjarnsholt, Thomas & Coenye, T., 2019, In: Trends in Microbiology. 27, 10, p. 850-863

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Shotgun sequencing of clinical biofilm following scanning electron microscopy identifies bacterial community composition

    Fritz, Blaine Gabriel, Stavnsbjerg, Camilla, Markvart, Merete, Damgaard, P. D. B., Nielsen, Sofie Holtsmark, Bjørndal, Lars, Qvortrup, Klaus & Bjarnsholt, Thomas, 2019, In: Pathogens and Disease. 77, 1, 7 p., ftz013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth

    Høiby, Niels, Henneberg, K. Å., Wang, H., Stavnsbjerg, Camilla, Bjarnsholt, Thomas, Ciofu, Oana, Johansen, U. R. & Sams, T., 2019, In: International Journal of Antimicrobial Agents. 53, 5, p. 564-573

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    In vivo gentamicin susceptibility test for prevention of bacterial biofilms in bone tissue and on implants

    Jensen, Louise Kruse, Bjarnsholt, Thomas, Kragh, K. N., Aalbæk, Bent, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie, Pankoke, K., Petersen, A. & Jensen, Henrik Elvang, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, 10 p., e01889-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air

    Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Understanding the microbiome of diabetic foot osteomyelitis: insights from molecular and microscopic approaches

    Johani, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Lipsky, B. A., Jensen, S. O., Yang, M., Dean, A., Hu, H., Vickery, K. & Malone, M., 2019, In: Clinical Microbiology and Infection. 25, 3, p. 332-339

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    An equine wound model to study effects of bacterial aggregates on wound healing

    Jørgensen, Elin , Bay, Lene, Skovgaard, Lene Theil, Bjarnsholt, Thomas & Jacobsen, Stine, 2019, In: Advances in Wound Care. 8, 10, p. 487-498

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Into the well—A close look at the complex structures of a microtiter biofilm and the crystal violet assay

    Kragh, K. N., Alhede, M., Kvich, Lasse Andersson & Bjarnsholt, Thomas, 2019, In: Biofilm. 1, 9 p., 100006.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Oxygen restriction generates difficult-to-culture p. Aeruginosa

    Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, K. N., Kolpen, Mette, Sønderholm, M., Andersson, M., Koch, A., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Analysis of proximal bone margins in diabetic foot osteomyelitis by conventional culture, DNA sequencing and microscopy

    Malone, M., Fritz, Blaine Gabriel, Vickery, K., Schwarzer, S., Sharma, V., Biggs, N., Radzieta, M., Jeffries, T. T., Dickson, H. G., Jensen, S. O. & Bjarnsholt, Thomas, 2019, In: APMIS. 127, 10, p. 660-670 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

    Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Is pseudarthrosis after spinal instrumentation caused by a chronic infection?

    Ohrt-Nissen, S., Fritz, Blaine Gabriel, Valentin, L., Kragh, K. N., Manniche, C., Dahl, B. & Bjarnsholt, Thomas, 2019, In: European Spine Journal. 28, p. 2996–3002

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2018
  54. Published

    The use of fluorescent staining techniques for microscopic investigation of polymorphonuclear leukocytes and bacteria

    Alhede, M., Stavnsbjerg, Camilla & Bjarnsholt, Thomas, 2018, In: APMIS. 126, 10, p. 779-794 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

ID: 9755066