Thomas Bjarnsholt

Thomas Bjarnsholt

Professor


  1. Published

    Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?

    Aanæs, Kasper, Eickhardt, S., Johansen, Helle Krogh, von Buchwald, Christian, Skov, M., Høiby, Niels & Bjarnsholt, Thomas, 2014, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. p. 1-7 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. Published

    3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism

    Adams, Yvonne, Clausen, Anne Skovsbo, Jensen, Peter Østrup, Lager, M., Wilhelmsson, P., Henningson, A. J., Lindgren, P. E., Faurholt-Jepsen, D., Mens, H., Kraiczy, P., Kragh, K. N., Bjarnsholt, Thomas, Kjær, Andreas, Lebech, Anne-Mette & Jensen, Anja Ramstedt, 2023, In: iScience. 26, 1, 105838.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    The use of fluorescent staining techniques for microscopic investigation of polymorphonuclear leukocytes and bacteria

    Alhede, M., Stavnsbjerg, Camilla & Bjarnsholt, Thomas, 2018, In: APMIS. 126, 10, p. 779-794 16 p.

    Research output: Contribution to journalReviewpeer-review

  4. Published

    Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes

    Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, Lene & Bjarnsholt, Thomas, 2020, In: Medical Microbiology and Immunology. 209, p. 669–680

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    The origin of extracellular DNA in bacterial biofilm infections in vivo

    Alhede, M., Alhede, M., Qvortrup, Klaus, Kragh, K. N., Jensen, Peter Østrup, Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Pathogens and Disease. ftaa018.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Pseudomonas aeruginosa Biofilms: Mechanisms of Immune Evasion

    Alhede, M., Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., 2014, In: Advances in Applied Microbiology. 86, p. 1-40 40 p.

    Research output: Contribution to journalJournal article

  7. Published

    Are biofilms responsible for the adverse effects experienced following soft-tissue fillers?

    Alhede, M. & Bjarnsholt, Thomas, 2014, In: Future Microbiology. 9, 8, p. 931-3 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Microbial biofilms and adverse reactions to gel fillers used in cosmetic surgery

    Alhede, M., Christensen, L. H. & Bjarnsholt, Thomas, 2015, In: Advances in Experimental Medicine and Biology. 831, p. 45-52 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Bacterial biofilm formation and treatment in soft tissue fillers

    Alhede, M., Er, O., Eickhardt, S., Kragh, K., Alhede, M., Hultqvist, Louise Dahl, Poulsen, Steen Seier, Givskov, Michael, Christensen, L. H., Høiby, Niels, Tvede, M. & Bjarnsholt, Thomas, 30 Jan 2014, In: Pathogens and Disease. 70, p. 339-346 8 p.

    Research output: Contribution to journalJournal article

  10. Published

    Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes

    Alhede, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Phipps, R. K., Moser, Claus Ernst, Christophersen, L., Hultqvist, Louise Dahl, van Gennip, M., Parsek, M., Høiby, Niels, Rasmussen, T. B. & Givskov, Michael, 2009, In: Microbiology. 155, 11, p. 3500-3508 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Combination of microscopic techniques reveals a comprehensive visual impression of biofilm structure and composition

    Alhede, M., Qvortrup, Klaus, Liebrechts, R., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 335-342 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Phenotype of non-attached Pseudomonas aeruginosa microclonies resembles attached biofilm, including reversible antibiotic tolerance

    Alhede, M., Qvortrup, K., Allesen-Holm, M., van Gennip, M., Christensen, L., Jensen, Peter Østrup, Nielsen, A., Tolker-Nielsen, T., Høiby, Niels, Givskov, M. C. & Bjarnsholt, Thomas, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  13. Published

    Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm

    Alhede, M., Kragh, K. N., Qvortrup, Klaus, Allesen-Holm, M., van Gennip, M., Hultqvist, Louise Dahl, Jensen, Peter Østrup, Nielsen, A. K., Parsek, M., Wozniak, D., Molin, S., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2011, In: P L o S One. 6, 11, p. e27943

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Minimum information guideline for spectrophotometric and fluorometric methods to assess biofilm formation in microplates

    Allkja, J., Bjarnsholt, Thomas, Coenye, T., Cos, P., Fallarero, A., Harrison, J. J., Lopes, S. P., Oliver, A., Pereira, M. O., Ramage, G., Shirtliff, M. E., Stoodley, P., Webb, J. S., Zaat, S. A. J., Goeres, D. M. & Azevedo, N. F., 2020, In: Biofilm. 2, 8 p., 100010.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Quorum-sensing-regulated virulence factors in Pseudomonas aeruginosa are toxic to Lucilia sericata maggots

    Andersen, A. S., Joergensen, B., Bjarnsholt, Thomas, Johansen, H., Karlsmark, T., Givskov, Michael, Krogfelt, K. A., Andersen, A. S., Jørgensen, B., Bjarnsholt, T., Johansen, H., Karlsmark, Tonny, Givskov, M. & Krogfelt, K. A., 1 Feb 2010, In: Microbiology. 156, Pt 2, p. 400-7 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Comparison of UVB and UVC irradiation disinfection efficacies on Pseudomonas Aeruginosa (P. aeruginosa) biofilm

    Argyraki, A., Markvart, Merete, Nielsen, Anne Kirstine, Bjarnsholt, Thomas, Bjørndal, Lars & Petersen, P. M., 2016, Biophotonics: Photonic Solutions for Better Health Care V. SPIE - International Society for Optical Engineering, Vol. 9887. 7 p. 988730. (Proceedings of S P I E - International Society for Optical Engineering, Vol. 9887).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  17. Published

    UV light assisted antibiotics for eradication of in vitro biofilms

    Argyraki, A., Markvart, Merete, Stavnsbjerg, Camilla, Kragh, K. N., Ou, Y., Bjørndal, Lars, Bjarnsholt, Thomas & Petersen, P. M., 2018, In: Scientific Reports. 8, p. 1-9 16360.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Inactivation of Pseudomonas aeruginosa biofilm after ultraviolet light-emitting diode treatment: a comparative study between ultraviolet C and ultraviolet B

    Argyraki, A., Markvart, Merete, Bjørndal, Lars, Bjarnsholt, Thomas & Petersen, P. M., 2017, In: Journal of Biomedical Optics. 22, 6, 7 p., 65004.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    A UVC device for intra-luminal disinfection of catheters: In vitro tests on soft polymer tubes contaminated with Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli and Candida albicans

    Bak, J., Begovic, T., Bjarnsholt, Thomas & Nielsen, A., 2011, In: Photochemistry and Photobiology. 87, 5, p. 1123-1128 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    A simplified bacterial community found within the epidermis than at the epidermal surface of atopic dermatitis patients and healthy controls

    Barnes, Christopher James, Asplund, M., Clausen, M., Rasmussen, Linett, Olesen, C. M., Yüksel, Y. T., Andersen, P. S., Litman, Thomas, Holmstrøm, K., Bay, Lene, Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Agner, Tove & Hansen, Anders Johannes, 2023, In: BMC Microbiology. 23, 12 p., 273.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    HUMAN SKIN MICROORGANISMS ARE DISTRIBUTED IN BIOFILM AGGREGATES AT WOUND EDGES

    Bay, Lene, Agren, M. S., Poulsen, Steen Seier, Ghathian, K. S. A., Calum, H. & Bjarnsholt, Thomas, 2015, In: Wound Repair and Regeneration. 23, 4, p. A3-A3 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  22. Published

    Universal Dermal Microbiome in Human Skin

    Bay, Lene, Barnes, Christopher James, Fritz, Blaine Gabriel, Thorsen, Jonathan Jan Ilve, Restrup, M. E. M., Rasmussen, Linett, Sørensen, J. K., Hesselvig, A. B., Odgaard, Anders, Hansen, Anders Johannes & Bjarnsholt, Thomas, 2020, In: mBio. 11, 1, 13 p., e02945-19.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Bacterial Aggregates Establish at the Edges of Acute Epidermal Wounds

    Bay, Lene, Kragh, K. N., Eickhardt, S. R., Poulsen, Steen Seier, Gjerdrum, Lise Mette Rahbek, Ghathian, K., Calum, Henrik Pierre, Ågren, Magnus & Bjarnsholt, Thomas, Apr 2018, In: Advances in Wound Care. 7, 4, p. 105-113

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Protocol to assess metabolic activity of Pseudomonas aeruginosa by measuring heat flow using isothermal calorimetry

    Beilharz, K., Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim, Bjarnsholt, Thomas & Lichtenberg, Mads, 2023, In: STAR Protocols. 4, 2, 102269.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    The gut microbiota can orchestrate the signaling pathways in colorectal cancer

    Bennedsen, A. L. B., Furbo, S., Bjarnsholt, Thomas, Raskov, H., Gögenur, Ismail & Kvich, Lasse Andersson, 2022, In: APMIS. 130, 3, p. 121-139 19 p.

    Research output: Contribution to journalReviewpeer-review

  26. Published

    Biofilm formation – what we can learn from recent developments

    Bjarnsholt, Thomas, Buhlin, K., Dufrêne, Y. F., Gomelsky, M., Moroni, A., Ramstedt, M., Rumbaugh, K. P., Schulte, T., Sun, L., Åkerlund, B. & Römling, U., 2018, In: Journal of Internal Medicine. 284, 4, p. 332-345 14 p.

    Research output: Contribution to journalReviewpeer-review

  27. Published

    Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control

    Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 2010, In: Expert Reviews in Molecular Medicine. 12, p. e11 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Process for the manufacture of ajoene derivatives

    Bjarnsholt, Thomas, Høiby, Niels, Jensen, Peter Østrup, Phipps, R., Shanmugham, Meenakshi, S., Alhede, M., Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Tanner, D., Larsen, Thomas, O. & Givskov, Michael, 14 Jun 2012, IPC No. C07C 323/ 65 A I, Patent No. WO2012076016, Priority date 8 Dec 2010, Priority No. EP20100194154

    Research output: Patent

  29. Published

    Silver against Pseudomonas aeruginosa biofilms

    Bjarnsholt, Thomas, Kirketerp-Møller, K., Kristiansen, S., Phipps, R., Nielsen, A. K., Jensen, Peter Østrup, Høiby, Niels & Givskov, Michael, 2007, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 115, 8, p. 921-8 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Detection of Bacteria by Fluorescence in Situ Hybridization in Culture-Negative Soft Tissue Filler Lesions

    Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Givskov, Michael, Janssen, M. & Christensen, L. H., 2009, In: Dermatologic Surgery. 35 Suppl 2, p. 1620-1624 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Biofilm infections

    Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup & Høiby, Niels, 2011, Springer New York. 314 p.

    Research output: Book/ReportBookpeer-review

  32. Published

    The importance of understanding the infectious microenvironment

    Bjarnsholt, Thomas, Whiteley, M., Rumbaugh, K. P., Stewart, P. S., Jensen, Peter Østrup & Frimodt-Møller, N., 2022, In: The Lancet Infectious Diseases. 22, 3, p. e88-e92

    Research output: Contribution to journalReviewpeer-review

  33. Published

    Applying insights from biofilm biology to drug development - can a new approach be developed?

    Bjarnsholt, Thomas, Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Oct 2013, In: Nature Reviews. Drug Discovery. 12, 10, p. 791-808 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    The role of bacterial biofilms in chronic infections

    Bjarnsholt, Thomas, May 2013, In: APMIS Supplementum. 121, s136, p. 1-58 58 p.

    Research output: Contribution to journalJournal article

  35. Published

    The in vivo biofilm

    Bjarnsholt, Thomas, Alhede, M., Alhede, M., Eickhardt-Sørensen, S. R., Moser, Claus Ernst, Kühl, Michael, Jensen, Peter Østrup & Høiby, Niels, 2013, In: Trends in Microbiology. 21, 9, p. 466-474 9 p.

    Research output: Contribution to journalReviewpeer-review

  36. Published

    Quorum sensing inhibitory drugs as next generation antimicrobials: worth the effort?

    Bjarnsholt, Thomas & Givskov, Michael, 2008, In: Current Infectious Disease Reports. 10, 1, p. 22-28 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Antibiofilm Properties of Acetic Acid

    Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. The role of quorum sensing in the pathogenicity of the cunning aggressor Pseudomonas aeruginosa

    Bjarnsholt, Thomas & Givskov, M., 2006, In: Analytical and Bioanalytical Chemistry. 387, 2, p. 409-14 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

    Bjarnsholt, Thomas, Jensen, P. Ø., Burmølle, M., Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, C., Molin, S., Høiby, Niels & Givskov, M. C., 1 Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Methods to classify bacterial pathogens in cystic fibrosis

    Bjarnsholt, Thomas, Nielsen, X. C., Johansen, U., Nørgaard, L. & Høiby, Niels, 2011, In: Methods in Molecular Biology. 742, p. 143-71 29 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients

    Bjarnsholt, Thomas, Jensen, Peter Østrup, Fiandaca, M. J., Pedersen, J., Hansen, C. R., Andersen, C. B., Pressler, T., Givskov, Michael & Høiby, Niels, 1 Jun 2009, In: Pediatric Pulmonology. 44, 6, p. 547-58 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections

    Bjarnsholt, Thomas, Jensen, P. Ø., Rasmussen, T. B., Christophersen, L., Calum, H., Hentzer, M., Hougen, H., Rygaard, J., Moser, C., Eberl, L., Høiby, N. & Givskov, M., 2005, In: Microbiology. 151, Pt 12, p. 3873-80 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction

    Bjarnsholt, Thomas, Jensen, Peter Østrup & Alhede, M., 2019, In: Pathogens and Disease. 77, 5, ftz052.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    APMIS 2022 focus issue on human microbiome in disease and pathology

    Bjarnsholt, Thomas, Ralfkiaer, U. & Malone, M., 2022, In: APMIS. 130, 12, p. 689 1 p.

    Research output: Contribution to journalEditorialpeer-review

  45. Published

    Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudo-monas aeruginosa infections.

    Bjarnsholt, Thomas, Jensen, P. Ø., Rasmussen, T. B., Christoffersen, L., Calum, Henrik Pierre, Hentzer, M., Hougen, H. P., Rygaard, J., Moser, Claus Ernst, Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: F E M S Microbiology. 151, p. 3873-3880 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Understanding biofilms - Are we there yet?

    Bjarnsholt, Thomas, Høiby, Niels, Donelli, G., Imbert, C. & Försberg, A., Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 125-126 2 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Introduction to biofilms

    Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer New York, p. 1-9 9 p.

    Research output: Chapter in Book/Report/Conference proceedingPreface/postscriptResearchpeer-review

  48. Published

    Introduction to Biofilm Infections

    Bjarnsholt, Thomas, 2010, Biofilm Infections. New York

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  49. Published

    Summary and Perspectives

    Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, 2010, Biofilm Infections. Bjarnsholt, T., Moser, C. E., Jensen, P. Ø. & Høiby, N. (eds.). 1st ed. New York. NY. US: Springer Science+Business Media, p. 291-293 3 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  50. Published

    In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect

    Bjarnsholt, Thomas, van Gennip, M., Jakobsen, Tim Holm, Hultqvist, Louise Dahl, Jensen, Peter Østrup & Givskov, Michael, 2010, In: Nature Protocols (Print Edition). 5, 2, p. 282-93 12 p.

    Research output: Contribution to journalJournal articlepeer-review

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ID: 9755066