Thomas Bjarnsholt

Thomas Bjarnsholt

Professor


  1. 2018
  2. Published

    UV light assisted antibiotics for eradication of in vitro biofilms

    Argyraki, A., Markvart, Merete, Stavnsbjerg, Camilla, Kragh, K. N., Ou, Y., Bjørndal, Lars, Bjarnsholt, Thomas & Petersen, P. M., 2018, In: Scientific Reports. 8, p. 1-9 16360.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Bacterial Aggregates Establish at the Edges of Acute Epidermal Wounds

    Bay, Lene, Kragh, K. N., Eickhardt, S. R., Poulsen, Steen Seier, Gjerdrum, Lise Mette Rahbek, Ghathian, K., Calum, Henrik Pierre, Ågren, Magnus & Bjarnsholt, Thomas, Apr 2018, In: Advances in Wound Care. 7, 4, p. 105-113

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Implants induce a new niche for microbiomes

    Jakobsen, Tim Holm, Eickhardt, S. R., Gheorghe, Alexandra Gabriella, Stenqvist, C., Sønderholm, M., Stavnsberg, C., Jensen, Peter Østrup, Odgaard, Anders, Whiteley, M., Moser, Claus Ernst, Hvolris, J., Hougen, H. P. & Bjarnsholt, Thomas, 1 Aug 2018, In: APMIS - Journal of Pathology, Microbiology and Immunology. 126, 8, p. 685-692 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Extreme high local intra-operative gentamicin concentrations are needed to prevent biofilm formation in-vivo

    Jensen, Louise Kruse, Bjarnsholt, Thomas, Henriksen, Nicole Lind, Kragh, K. N. & Jensen, Henrik Elvang, 6 Sep 2018.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  6. Published

    Bacterial biofilm formation inside colonic crypts may accelerate colorectal carcinogenesis

    Raskov, H., Kragh, K. N., Bjarnsholt, Thomas, Alamili, M. & Gögenur, Ismail, 17 Sep 2018, In: Clinical and Translational Medicine. 7, 4 p., 30.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Samspillet mellem mikrobiota og immunsystemet ved kolorektal cancer

    Raskov, H., Bjarnsholt, Thomas, Alamili, M., Kragh, K. N. & Gögenur, Ismail, 5 Nov 2018, In: Ugeskrift for Laeger. 180, 45, V04180253.

    Research output: Contribution to journalJournal articlepeer-review

  8. 2019
  9. Published

    An equine wound model to study effects of bacterial aggregates on wound healing

    Jørgensen, Elin , Bay, Lene, Skovgaard, Lene Theil, Bjarnsholt, Thomas & Jacobsen, Stine, 2019, In: Advances in Wound Care. 8, 10, p. 487-498

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Analysis of proximal bone margins in diabetic foot osteomyelitis by conventional culture, DNA sequencing and microscopy

    Malone, M., Fritz, Blaine Gabriel, Vickery, K., Schwarzer, S., Sharma, V., Biggs, N., Radzieta, M., Jeffries, T. T., Dickson, H. G., Jensen, S. O. & Bjarnsholt, Thomas, 2019, In: APMIS. 127, 10, p. 660-670 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms

    Crabbé, A., Jensen, Peter Østrup, Bjarnsholt, Thomas & Coenye, T., 2019, In: Trends in Microbiology. 27, 10, p. 850-863

    Research output: Contribution to journalReviewpeer-review

  12. Published

    Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth

    Høiby, Niels, Henneberg, K. Å., Wang, H., Stavnsbjerg, Camilla, Bjarnsholt, Thomas, Ciofu, Oana, Johansen, U. R. & Sams, T., 2019, In: International Journal of Antimicrobial Agents. 53, 5, p. 564-573

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

    Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air

    Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-jepsen, D., Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    In Situ Monitoring of the Antibacterial Activity of a Copper-Silver Alloy Using Confocal Laser Scanning Microscopy and pH Microsensors

    Ciacotich, N., Kragh, K. N., Lichtenberg, Mads, Tesdorpf, J. E., Bjarnsholt, Thomas & Gram, L., 2019, In: Global Challenges. 3, 11, 9 p., 1900044.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    In vivo gentamicin susceptibility test for prevention of bacterial biofilms in bone tissue and on implants

    Jensen, Louise Kruse, Bjarnsholt, Thomas, Kragh, K. N., Aalbæk, Bent, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie, Pankoke, K., Petersen, A. & Jensen, Henrik Elvang, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, 10 p., e01889-18.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Into the well—A close look at the complex structures of a microtiter biofilm and the crystal violet assay

    Kragh, K. N., Alhede, M., Kvich, Lasse Andersson & Bjarnsholt, Thomas, 2019, In: Biofilm. 1, 9 p., 100006.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Is pseudarthrosis after spinal instrumentation caused by a chronic infection?

    Ohrt-Nissen, S., Fritz, Blaine Gabriel, Valentin, L., Kragh, K. N., Manniche, C., Dahl, B. & Bjarnsholt, Thomas, 2019, In: European Spine Journal. 28, p. 2996–3002

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Oxygen restriction generates difficult-to-culture p. Aeruginosa

    Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, K. N., Kolpen, Mette, Sønderholm, M., Andersson, M., Koch, A., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction

    Bjarnsholt, Thomas, Jensen, Peter Østrup & Alhede, M., 2019, In: Pathogens and Disease. 77, 5, ftz052.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published
  22. Published

    Understanding the microbiome of diabetic foot osteomyelitis: insights from molecular and microscopic approaches

    Johani, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Lipsky, B. A., Jensen, S. O., Yang, M., Dean, A., Hu, H., Vickery, K. & Malone, M., 2019, In: Clinical Microbiology and Infection. 25, 3, p. 332-339

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Extensive debridement is fundamental for the success of an absorbable gentamicin loaded bio-composite

    Jensen, Louise Kruse, Blirup-Plum, Sophie Amalie, Aalbæk, Bent, Bjarnsholt, Thomas, Kragh, K. N., Gottlieb, H., Bue, M. & Jensen, Henrik Elvang, 12 Sep 2019.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  24. 2020
  25. Published

    Staphylococcus aureus augments release of matrix metalloproteinase-8 from human polymorphonuclear leukocytes

    Kirketerp-Møller, K., Bjarnsholt, Thomas, Jensen, Peter Østrup & Ågren, Magnus, 2020, In: Acta Dermato-Venereologica. 100, 15, p. 1-2 2 p., adv00232.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Antibiotic susceptibility of cystic fibrosis lung microbiome members in a multispecies biofilm

    Vandeplassche, E., Sass, A., Ostyn, L., Burmølle, Mette, Kragh, K. N., Bjarnsholt, Thomas, Coenye, T. & Crabbé, A., 2020, In: Biofilm. 2, 9 p., 100031.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes

    Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, Lene & Bjarnsholt, Thomas, 2020, In: Medical Microbiology and Immunology. 209, p. 669–680

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

    Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Copper-Silver alloy coated door handles as a potential antibacterial strategy in clinical settings

    Ciacotich, N., Kvich, Lasse Andersson, Sanford, N., Wolcott, J., Bjarnsholt, Thomas & Gram, L., 2020, In: Coatings. 10, 8, 9 p., 790.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Do Mixed-Species Biofilms Dominate in Chronic Infections? Need for in situ Visualization of Bacterial Organization

    Kvich, Lasse Andersson, Burmølle, Mette, Bjarnsholt, Thomas & Lichtenberg, Mads, 2020, In: Frontiers in Cellular and Infection Microbiology. 10, 12 p., 396.

    Research output: Contribution to journalReviewpeer-review

  31. Published

    Does an Antimicrobial Incision Drape Prevent Intraoperative Contamination? A Randomized Controlled Trial of 1187 Patients

    Hesselvig, A. B., Arpi, M., Madsen, F., Bjarnsholt, Thomas, Odgaard, Anders & ICON Study Group, I. S. G., 2020, In: Clinical Orthopaedics and Related Research. 478, 5, p. 1007-1015

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology

    Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Eradication of biofilms on tympanostomy tubes with acetic acid treatment: an in vitro study

    Kjeldsen, M., Homøe, Preben, Nielsen, Anne Kirstine, Crone, S., Nørskov Kragh, K. & Bjarnsholt, Thomas, 2020, In: APMIS. 128, 6, p. 445-450

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Histologic changes and gene expression patterns in biopsy specimens from bacteria-inoculated and noninoculated excisional body and limb wounds in horses healing by second intention

    Jørgensen, Elin , Hjerpe, F. B., Hougen, H. P., Bjarnsholt, Thomas, Berg, Lise Charlotte & Jacobsen, Stine, 2020, In: American Journal of Veterinary Research. 81, 3, p. 276-284 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Minimum information guideline for spectrophotometric and fluorometric methods to assess biofilm formation in microplates

    Allkja, J., Bjarnsholt, Thomas, Coenye, T., Cos, P., Fallarero, A., Harrison, J. J., Lopes, S. P., Oliver, A., Pereira, M. O., Ramage, G., Shirtliff, M. E., Stoodley, P., Webb, J. S., Zaat, S. A. J., Goeres, D. M. & Azevedo, N. F., 2020, In: Biofilm. 2, 8 p., 100010.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Pathogenic CD8+ epidermis-resident memory T cells displace dendritic epidermal T cells in allergic dermatitis

    Ø Gadsbøll, A., Jee, Mia Hamilton, Funch, Anders Boutrup, Alhede, M., Mraz, Veronika, Weber, Julie Friis, Callender, L. A., Carroll, E. C., Bjarnsholt, Thomas, Woetmann, Anders , Ødum, Niels, Thomsen, Allan Randrup, Johansen, Jeanne Duus, Henson, S. M., Geisler, Carsten & Bonefeld, Charlotte Menne, 2020, In: The Journal of Investigative Dermatology. 140, 4, p. 806-815.e5

    Research output: Contribution to journalJournal articlepeer-review

  37. Published
  38. Published

    Predictive Metagenomic Analysis Reveals a Role of Cutaneous Dysbiosis in the Development of Hidradenitis Suppurativa

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Jørgensen, A. H., Bay, Lene, Bjarnsholt, Thomas, Fuursted, K., Thomsen, Simon Francis & Jemec, Gregor, 2020, In: Journal of Investigative Dermatology. 140, 7, p. 1473-1476

    Research output: Contribution to journalLetterpeer-review

  39. Published

    Risk factors for chronic biofilm-related infection associated with implanted medical devices

    Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Clinical Microbiology and Infection. 26, 8, p. 1034-1038

    Research output: Contribution to journalReviewpeer-review

  40. Published

    The efficacy of topical agents used in wounds for managing chronic biofilm infections: A systematic review

    Schwarzer, S., James, G. A., Goeres, D., Bjarnsholt, Thomas, Vickery, K., Percival, S. L., Stoodley, P., Schultz, G., Jensen, S. O. & Malone, M., 2020, In: Journal of Infection. 80, 3, p. 261-270

    Research output: Contribution to journalReviewpeer-review

  41. Published

    The environmental occurrence of Pseudomonas aeruginosa

    Crone, S., Vives-Flórez, M., Kvich, Lasse Andersson, Saunders, A. M., Malone, M., Nicolaisen, Mette Haubjerg, Martínez-García, E., Rojas-Acosta, C., Catalina Gomez-Puerto, M., Calum, Henrik Pierre, Whiteley, M., Kolter, R. & Bjarnsholt, Thomas, 2020, In: APMIS. 128, 3, p. 220-231

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    The future of biofilm research – Report on the ‘2019 Biofilm Bash’

    Coenye, T., Kjellerup, B., Stoodley, P. & Bjarnsholt, Thomas, 2020, In: Biofilm. 2, 9 p., 100012.

    Research output: Contribution to journalComment/debatepeer-review

  43. Published

    The origin of extracellular DNA in bacterial biofilm infections in vivo

    Alhede, M., Alhede, M., Qvortrup, Klaus, Kragh, K. N., Jensen, Peter Østrup, Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Pathogens and Disease. ftaa018.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    The zone model: A conceptual model for understanding the microenvironment of chronic wound infection

    Kirketerp-Møller, K., Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Wound Repair and Regeneration. 28, 5, p. 593-599

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Universal Dermal Microbiome in Human Skin

    Bay, Lene, Barnes, Christopher James, Fritz, Blaine Gabriel, Thorsen, Jonathan Jan Ilve, Restrup, M. E. M., Rasmussen, Linett, Sørensen, J. K., Hesselvig, A. B., Odgaard, Anders, Hansen, Anders Johannes & Bjarnsholt, Thomas, 2020, In: mBio. 11, 1, 13 p., e02945-19.

    Research output: Contribution to journalJournal articlepeer-review

  46. 2021
  47. Published

    A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of antimicrobial solutions and wound dressings

    Chen, X., Lorenzen, J., Xu, Y., Jonikaite, M., Thaarup, Ida Clement, Bjarnsholt, Thomas, Kirketerp-Møller, K. & Thomsen, T. R., 2021, In: Wound Repair and Regeneration. 29, 5, p. 820-829

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    APMIS pandemic editorial

    Bjarnsholt, Thomas & Calum, Henrik Pierre, 2021, In: APMIS: Acta Pathologica, Microbiologica et Immunologica Scandinavica. 129, 7, p. 319 1 p.

    Research output: Contribution to journalEditorialpeer-review

  49. Published

    Biofilm Research in Bovine Mastitis

    Pedersen, Regitze Renee, Krömker, Volker, Bjarnsholt, Thomas, Dahl-Pedersen, Kirstin, Buhl, Rikke & Jørgensen, Elin , 2021, In: Frontiers in Veterinary Science. 8, 11 p., 656810.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Biofilm and equine limb wounds

    Jørgensen, Elin , Bjarnsholt, Thomas & Jacobsen, Stine, 2021, In: Animals. 11, 10, 2825.

    Research output: Contribution to journalReviewpeer-review

  51. Published

    Biofilms can act as plasmid reserves in the absence of plasmid specific selection

    Røder, Henriette Lyng, Trivedi, Urvish, Russel, J., Kragh, K. N., Herschend, J., Thalsø-Madsen, I., Tolker-Nielsen, Tim, Bjarnsholt, Thomas, Burmølle, Mette & Madsen, Jonas Stenløkke, 2021, In: npj Biofilms and Microbiomes. 7, 6 p., 78.

    Research output: Contribution to journalLetterpeer-review

  52. Published

    Catalase protects biofilm of Staphylococcus aureus against daptomycin activity

    El Haj, C., Lichtenberg, Mads, Nielsen, K. L., Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: Antibiotics. 10, 5, 511.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Current in vitro biofilm-infected chronic wound models for developing new treatment possibilities

    Thaarup, Ida Clement & Bjarnsholt, Thomas, 2021, In: Advances in Wound Care. 10, 2, p. 91-102 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    Dynamics of skin microbiota in shoulder surgery infections

    Fatima, N., Bjarnsholt, Thomas & Bay, Lene, 2021, In: APMIS. 129, 12, p. 665-674

    Research output: Contribution to journalReviewpeer-review

  55. Published

    Measuring enzymatic degradation of degradable starch microspheres using confocal laser scanning microscopy

    Thaarup, Ida Clement, Gummesson, C. & Bjarnsholt, Thomas, 2021, In: Acta Biomaterialia. 131, p. 464-471

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa

    Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    Peptidoglycan-Binding Anchor Is a Pseudomonas aeruginosa OmpA Family Lipoprotein With Importance for Outer Membrane Vesicles, Biofilms, and the Periplasmic Shape

    Paulsson, M., Kragh, K. N., Su, Y. C., Sandblad, L., Singh, B., Bjarnsholt, Thomas & Riesbeck, K., 2021, In: Frontiers in Microbiology. 12, 639582.

    Research output: Contribution to journalJournal articlepeer-review

  58. Published

    Sampling challenges in diagnosis of chronic bacterial infections

    Jakobsen, Tim Holm, Xu, Y., Bay, Lene, Schønheyder, H. C., Jakobsen, T., Bjarnsholt, Thomas & Thomsen, T. R., 2021, In: Journal of Medical Microbiology. 70, 3

    Research output: Contribution to journalReviewpeer-review

  59. Published

    The discovery of bacterial biofilm in patients with muscle invasive bladder cancer

    Nadler, N., Kvich, Lasse Andersson, Bjarnsholt, Thomas, Jensen, J. B., Gögenur, Ismail & Azawi, Nessn H., 2021, In: APMIS. 129, 5, p. 265-270

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    The impact of mental models on the treatment and research of chronic infections due to biofilms

    Bjarnsholt, Thomas, Mastroianni, E., Kirketerp-Møller, K., Stewart, P. S., Mähr, A. M., Domínguez Cabañes, A. & Nørager, R., 2021, In: APMIS. 129, 10, p. 598-606

    Research output: Contribution to journalJournal articlepeer-review

  61. Published

    Delayed neutrophil recruitment allows nascent Staphylococcus aureus biofilm formation and immune evasion

    Pettygrove, B. A., Kratofil, R. M., Alhede, M., Jensen, Peter Østrup, Newton, M., Qvortrup, Klaus, Pallister, K. B., Bjarnsholt, Thomas, Kubes, P., Voyich, J. M. & Stewart, P. S., Aug 2021, In: Biomaterials. 275, 13 p., 120775.

    Research output: Contribution to journalJournal articlepeer-review

  62. 2022
  63. Published

    A novel Borrelia-specific real-time PCR assay is not suitable for diagnosing Lyme neuroborreliosis

    Pedersen, Regitze Renee, Kragh, K. N., Fritz, Blaine Gabriel, Ørbæk, M., Jensen, Peter Østrup, Lebech, Anne-Mette & Bjarnsholt, Thomas, 2022, In: Ticks and Tick-borne Diseases. 13, 5, 101971.

    Research output: Contribution to journalJournal articlepeer-review

  64. Published

    APMIS 2022 focus issue on human microbiome in disease and pathology

    Bjarnsholt, Thomas, Ralfkiaer, U. & Malone, M., 2022, In: APMIS. 130, 12, p. 689 1 p.

    Research output: Contribution to journalEditorialpeer-review

  65. Published

    Amplicon sequencing demonstrates comparable follicular mycobiomes in patients with hidradenitis suppurativa compared with healthy controls

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Egeberg, Alexander, Ingham, Andreas, Vedel Nielsen, H., Frew, J. W., Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 7, p. e580-e583 4 p.

    Research output: Contribution to journalComment/debate

  66. Published

    Bacterial biofilms predominate in both acute and chronic human lung infections

    Kolpen, M., Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, Pernille, Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: Thorax. 77, p. 1015–1022

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    Bacterial biofilms predominate in both acute and chronic human lung infections

    Kolpen, Mette, Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, P., Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: European Respiratory Journal. Supplement. 60, Suppl. 66, 4.

    Research output: Contribution to journalJournal articlepeer-review

  68. Published

    Biofilm Survival Strategies in Chronic Wounds

    Thaarup, Ida Clement, Iversen, A. K. S., Lichtenberg, Mads, Bjarnsholt, Thomas & Jakobsen, Tim Holm, 2022, In: Microorganisms. 10, 4, 775.

    Research output: Contribution to journalReviewpeer-review

  69. Published

    Biofilm antimicrobial susceptibility through an experimental evolutionary lens

    Coenye, T., Bové, M. & Bjarnsholt, Thomas, 2022, In: npj Biofilms and Microbiomes. 8, 82.

    Research output: Contribution to journalReviewpeer-review

  70. Published

    Cyclic-di-GMP signaling controls metabolic activity in Pseudomonas aeruginosa

    Lichtenberg, Mads, Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2022, In: Cell Reports. 41, 3, p. 111515 1 p.

    Research output: Contribution to journalJournal articlepeer-review

  71. Published

    Establishing a consensus on wound infection definitions

    Haesler, E., Swanson, T., Ousey, K., Larsen, D., Carville, K., Bjarnsholt, Thomas & Haesler, P., 2022, In: Journal of Wound Care. 31, S12, p. S48-S59

    Research output: Contribution to journalJournal articlepeer-review

  72. Published

    IWII Wound Infection in Clinical Practice consensus document: 2022 update

    Swanson, T., Ousey, K., Haesler, E., Bjarnsholt, Thomas, Carville, K., Idensohn, P., Kalan, L., Keast, D. H., Larsen, D., Percival, S., Schultz, G., Sussman, G., Waters, N. & Weir, D., 2022, In: Journal of Wound Care. 31, S12, p. S10-S21

    Research output: Contribution to journalJournal articlepeer-review

  73. Published

    Injection site microflora in persons with diabetes: why needle reuse is not associated with increased infections?

    Wareham-Mathiassen, S., Bay, Lene, Glenting, V. P., Fatima, N., Bengtsson, H. & Bjarnsholt, Thomas, 2022, In: APMIS. 130, 7, p. 404-416 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  74. Published

    Inoculum Concentration Influences Pseudomonas aeruginosa Phenotype and Biofilm Architecture

    Lichtenberg, Mads, Kvich, Lasse Andersson, Larsen, S. L. B., Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2022, In: Microbiology Spectrum. 10, 6

    Research output: Contribution to journalJournal articlepeer-review

  75. Published

    Investigation of the mechanism and chemistry underlying Staphylococcus aureus' ability to inhibit Pseudomonas aeruginosa growth in vitro

    Kvich, Lasse Andersson, Crone, S. G., Christensen, M. H., Lima, R. D. C. L., Alhede, M., Alhede, M., Stærk, Dan & Bjarnsholt, Thomas, 2022, In: Journal of Bacteriology. 204, 11, 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  76. Published

    Mucoid Pseudomonas aeruginosa Can Produce Calcium-Gelled Biofilms Independent of the Matrix Components Psl and CdrA

    Jacobs, H. M., O'Neal, L., Lopatto, E., Wozniak, D. J., Bjarnsholt, Thomas & Parsek, M. R., 2022, In: Journal of Bacteriology. 204, 5

    Research output: Contribution to journalJournal articlepeer-review

  77. Published

    Prevalence of biofilms in acute infections challenges a longstanding paradigm

    Kolpen, M., Jensen, Peter Østrup, Faurholt-Jepsen, D. & Bjarnsholt, Thomas, 2022, In: Biofilm. 4, 100080.

    Research output: Contribution to journalJournal articlepeer-review

  78. Published

    Probiotics in hidradenitis suppurativa: a potential treatment option?

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Clinical and Experimental Dermatology. 47, 1, p. 139-141 2 p.

    Research output: Contribution to journalComment/debate

  79. Published

    Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: protocol for a randomised, double-blind, placebo-controlled trial (The BREAST-AB trial)

    Hemmingsen, M. N., Larsen, A., Weltz, T. K., Ørholt, M., Wiberg, S., Bennedsen, A. K., Bille, C., Carstensen, L. F., Jensen, L. T., Bredgaard, R., Koudahl, V., Schmidt, Volker-Jürgen, Vester-Glowinski, Peter Viktor, Hølmich, Lisbet Rosenkrantz, Sørensen, Søren Johannes, Bjarnsholt, Thomas, Damsgaard, Tine M Engberg & Herly, Mikkel, 2022, In: BMJ Open. 12, 9, p. e058697

    Research output: Contribution to journalJournal articlepeer-review

  80. Published

    The Combination of Low-Frequency Ultrasound and Antibiotics Improves the Killing of In Vitro Staphylococcus aureus and Pseudomonas aeruginosa Biofilms

    Kvich, Lasse Andersson, Christensen, M. H., Pierchala, M. K., Astafiev, K., Lou-Moeller, R. & Bjarnsholt, Thomas, 2022, In: Antibiotics. 11, 11, 1494.

    Research output: Contribution to journalJournal articlepeer-review

  81. Published

    The biofilm life cycle: expanding the conceptual model of biofilm formation

    Sauer, K., Stoodley, P., Goeres, D. M., Hall-Stoodley, L., Burmølle, Mette, Stewart, P. S. & Bjarnsholt, Thomas, 2022, In: Nature Reviews Microbiology. 20, 10, p. 608-620 13 p.

    Research output: Contribution to journalReviewpeer-review

  82. Published

    The gut microbiota can orchestrate the signaling pathways in colorectal cancer

    Bennedsen, A. L. B., Furbo, S., Bjarnsholt, Thomas, Raskov, H., Gögenur, Ismail & Kvich, Lasse Andersson, 2022, In: APMIS. 130, 3, p. 121-139 19 p.

    Research output: Contribution to journalReviewpeer-review

  83. Published

    The importance of understanding the infectious microenvironment

    Bjarnsholt, Thomas, Whiteley, M., Rumbaugh, K. P., Stewart, P. S., Jensen, Peter Østrup & Frimodt-Møller, N., 2022, In: The Lancet Infectious Diseases. 22, 3, p. e88-e92

    Research output: Contribution to journalReviewpeer-review

  84. Published

    The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment

    Lichtenberg, Mads, Jakobsen, Tim Holm, Kühl, Michael, Kolpen, Mette, Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: FEMS Microbiology Reviews. 46, 5, 13 p., fuac018.

    Research output: Contribution to journalJournal articlepeer-review

  85. Published

    Transcriptomic Fingerprint of Bacterial Infection in Lower Extremity Ulcers

    Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Nielsen, C. H., Kirketerp-Møller, K., Malone, M. & Bjarnsholt, Thomas, 2022, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 130, 8, p. 524-534

    Research output: Contribution to journalJournal articlepeer-review

  86. Published

    Treatment of implant-associated osteomyelitis with injectable in situ-forming depot drug delivery system

    Fuglsang-Madsen, A., Henriksen, Nicole Lind, Kvich, Lasse Andersson, Birch, Julie Knippel Melsted, Hartmann, Katrine Top, Bjarnsholt, Thomas, Andresen, T. L., Jensen, Louise Kruse, Henriksen, J. R. & Hansen, A. E., 2022.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  87. 2023
  88. Published

    3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism

    Adams, Yvonne, Clausen, Anne Skovsbo, Jensen, Peter Østrup, Lager, M., Wilhelmsson, P., Henningson, A. J., Lindgren, P. E., Faurholt-Jepsen, D., Mens, H., Kraiczy, P., Kragh, K. N., Bjarnsholt, Thomas, Kjær, Andreas, Lebech, Anne-Mette & Jensen, Anja Ramstedt, 2023, In: iScience. 26, 1, 105838.

    Research output: Contribution to journalJournal articlepeer-review

  89. Published

    A collagen-based layered chronic wound biofilm model for testing antimicrobial wound products

    Thaarup, Ida Clement, Lichtenberg, Mads, Nørgaard, K. T. H., Xu, Y., Lorenzen, J., Thomsen, T. R. & Bjarnsholt, Thomas, 2023, In: Wound Repair and Regeneration. 31, 4, p. 500-515

    Research output: Contribution to journalJournal articlepeer-review

  90. Published

    A simplified bacterial community found within the epidermis than at the epidermal surface of atopic dermatitis patients and healthy controls

    Barnes, Christopher James, Asplund, M., Clausen, M., Rasmussen, Linett, Olesen, C. M., Yüksel, Y. T., Andersen, P. S., Litman, Thomas, Holmstrøm, K., Bay, Lene, Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Agner, Tove & Hansen, Anders Johannes, 2023, In: BMC Microbiology. 23, 12 p., 273.

    Research output: Contribution to journalJournal articlepeer-review

  91. Published

    Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C-30 during experimental evolution requires multiple genotypic and phenotypic changes

    Bové, M., Kolpen, Mette, Lichtenberg, Mads, Bjarnsholt, Thomas & Coenye, T., 2023, In: Microbiology (United Kingdom). 169, 1, 001278.

    Research output: Contribution to journalJournal articlepeer-review

  92. Published

    Biofilm formation on endovascular aneurysm repair (EVAR) grafts- a proof of concept in vitro model

    Sunnerhagen, T., Schwartz, F., Christophersen, L., Bjarnsholt, Thomas, Qvortrup, Klaus, Eldrup, Nikolaj, Vogt, K. & Moser, Claus Ernst, 2023, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 29, 12, p. 1600.e1-1600.e6 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  93. Published

    Cerebral abscesses with odontogenic origin: a population-based cohort study

    Jespersen, Frederik Viktor Bang, Hansen, S. U., Jensen, Simon Storgård, Omland, L. H., Helweg-Larsen, J., Bjarnsholt, Thomas, Nielsen, Claus Henrik, Ziebell, M., Bodilsen, J. & Markvart, Merete, 2023, In: Clinical Oral Investigations. 27, 7, p. 3639-364

    Research output: Contribution to journalJournal articlepeer-review

  94. Published
  95. Published

    Characterization of pig skin microbiome and appraisal as an in vivo subcutaneous injection model

    Wareham-Mathiassen, S., Pinto Glenting, V., Bay, Lene, Allesen-Holm, M., Bengtsson, H. & Bjarnsholt, Thomas, 2023, In: Laboratory Animals. 57, 2, p. 304-318

    Research output: Contribution to journalJournal articlepeer-review

  96. Published

    Defining the temporal relationship between the skin microbiome, immune response and skin barrier function during flare and resolution of atopic dermatitis: protocol of a Danish intervention study

    Rønnstad, A. T. M., Bay, Lene, Ruge, I. F., Halling, A., Fritz, Blaine Gabriel, Jakaša, I., Luiten, R., Kezic, S., Thomsen, Simon Francis, Bjarnsholt, Thomas & Thyssen, Jacob Pontoppidan, 2023, In: BMJ Open. 13, 2, 8 p., e068395.

    Research output: Contribution to journalJournal articlepeer-review

  97. Published

    Direct 16S/18S rRNA Gene PCR Followed by Sanger Sequencing as a Clinical Diagnostic Tool for Detection of Bacterial and Fungal Infections: a Systematic Review and Meta-Analysis

    Drevinek, P., Hollweck, R., Lorenz, M. G., Lustig, M. & Bjarnsholt, Thomas, 2023, In: Journal of clinical microbiology. 61, 9, e0033823.

    Research output: Contribution to journalReviewpeer-review

  98. Published

    E-cadherin and aquaporin-3 are downregulated in wound edges of human chronic wounds

    Ernstsen, C. V., Riishede, A., Iversen, A. K. S., Bay, Lene, Bjarnsholt, Thomas & Nejsum, L. N., 2023, In: APMIS. 131, 8, p. 403-409

    Research output: Contribution to journalJournal articlepeer-review

  99. Published

    Endolysin Inhibits Skin Colonization by Patient-Derived Staphylococcus Aureus and Malignant T-Cell Activation in Cutaneous T-Cell Lymphoma

    Pallesen, E. M. H., Gluud, M., Vadivel, C. K., Buus, T. B., de Rooij, B., Zeng, Z., Ahmad, S., Willerslev-Olsen, A., Röhrig, C., Kamstrup, M. R., Bay, L., Lindahl, L., Krejsgaard, T., Geisler, C., Bonefeld, C. M., Iversen, L., Woetmann, A., Koralov, S. B., Bjarnsholt, T., Frieling, J. & 2 others, Schmelcher, M. & Ødum, Niels, 2023, In: Journal of Investigative Dermatology. 143, 9, p. 1757-1769 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  100. Published

    Microbial Primer: In vivo biofilm

    Rumbaugh, K. P. & Bjarnsholt, Thomas, 2023, In: Microbiology (United Kingdom). 169, 12, 5 p., 001407.

    Research output: Contribution to journalJournal articlepeer-review

  101. Published

    Pharmacokinetics of Locally Applied Antibiotic Prophylaxis for Implant-Based Breast Reconstruction

    Hemmingsen, Mathilde Nejrup, Bennedsen, A. K., Kullab, R. B., Norlin, C. B., Ørholt, M., Larsen, A., Bue, M., Lichtenberg, Mads, Hertz, Frederik Boëtius, Damsgaard, T. E., Vester-Glowinski, Peter Viktor, Sørensen, Søren Johannes, Bjarnsholt, Thomas & Herly, Mikkel, 2023, In: JAMA network open. 6, 12, 11 p., E2348414.

    Research output: Contribution to journalJournal articlepeer-review

  102. Published

    Protocol to assess metabolic activity of Pseudomonas aeruginosa by measuring heat flow using isothermal calorimetry

    Beilharz, K., Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim, Bjarnsholt, Thomas & Lichtenberg, Mads, 2023, In: STAR Protocols. 4, 2, 102269.

    Research output: Contribution to journalJournal articlepeer-review

  103. Published

    Reduced Skin Microbiome Diversity in Infancy Is Associated with Increased Risk of Atopic Dermatitis in High-Risk Children

    Halling, A. S., Fritz, Blaine Gabriel, Gerner, T., Rinnov, M. R., Bay, Lene, Knudgaard, M. H., Ravn, N. H., Trautner, S., Ruge, I. F., Olesen, C., Díiaz-Pinées Cort, I., Skov, Lone, Sørensen, N., Møller Rønnstad, A. T., Thomsen, Simon Francis, Egeberg, Alexander, Jakasa, I., Kezic, S., Bjarnsholt, Thomas & Thyssen, Jacob Pontoppidan, 2023, In: Journal of Investigative Dermatology. 143, 10, p. 2030-2038 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  104. Published
  105. Published

    What's in a name? Characteristics of clinical biofilms

    Lichtenberg, Mads, Coenye, T., Parsek, M. R., Bjarnsholt, Thomas & Jakobsen, Tim Holm, 2023, In: FEMS Microbiology Reviews. 47, 5, p. 1-8 fuad050.

    Research output: Contribution to journalReviewpeer-review

  106. 2024
  107. E-pub ahead of print

    Antibiotic implant irrigation and deep infection: A retrospective study of 1508 patients undergoing breast reconstruction with implants

    Hemmingsen, Mathilde Nejrup, Bennedsen, A. K., Kullab, R. B., Weltz, T. K., Ørholt, M., Norlin, C. B., Kalstrup, J., Bredgaard, R., Sørensen, Søren Johannes, Bjarnsholt, Thomas, Hølmich, Lisbet Rosenkrantz, Damsgaard, T. E., Vester-Glowinski, Peter Viktor & Herly, Mikkel, 2024, (E-pub ahead of print) In: Plastic and Reconstructive Surgery. 26 p.

    Research output: Contribution to journalJournal articlepeer-review

ID: 9755066