Thomas Bjarnsholt
Professor
Bacteriology
Nørre Allé 14
2200 København N
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Symposium i Danmarks Mikrobiologiske Selskab
Jensen, L. B., Bjarnsholt, Thomas & Jacobsen, C. S., 2012, In: Ugeskrift for Laeger. 174, 12, p. 790 1 p.Research output: Contribution to journal › Journal article
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Summary and perspectives
Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, 2011, Biofilm Infections. Springer New York, p. 291-294 4 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Summary and Perspectives
Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, 2010, Biofilm Infections. Bjarnsholt, T., Moser, C. E., Jensen, P. Ø. & Høiby, N. (eds.). 1st ed. New York. NY. US: Springer Science+Business Media, p. 291-293 3 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Success rate of split-thickness skin grafting of chronic venous leg ulcers depends on the presence of Pseudomonas aeruginosa: a retrospective study
Høgsberg, T., Bjarnsholt, Thomas, Thomsen, J. S. & Kirketerp-Møller, K., 1 Jan 2011, In: P L o S One. 6, 5, p. e20492Research output: Contribution to journal › Journal article › peer-review
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Success rate of split-thickness skin grafting of chronic venous leg ulcers depends on the presence of Pseudomonas aeruginosa: a retrospective study
Høgsberg, T., Bjarnsholt, Thomas, Thomsen, J. S. & Kirketerp-Møller, K., 2011, In: P L o S One. 6, 5, p. e20492Research output: Contribution to journal › Journal article › peer-review
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Specific antibodies to Staphylococcus aureus biofilm are present in serum from pigs with osteomyelitis
Jensen, Louise Kruse, Jensen, Henrik Elvang, Koch, J., Bjarnsholt, Thomas, Eickhardt-Dalbøge, S. R. & Shirtliff, M., 2015, In: In Vivo. 29, p. 555-560 6 p.Research output: Contribution to journal › Journal article › peer-review
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Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?
Aanæs, Kasper, Eickhardt, S., Johansen, Helle Krogh, von Buchwald, Christian, Skov, M., Høiby, Niels & Bjarnsholt, Thomas, 2014, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. p. 1-7 7 p.Research output: Contribution to journal › Journal article › peer-review
- E-pub ahead of print
Single cells and bacterial biofilm populations in chronic wound infections
Lichtenberg, Mads, Kirketerp-Møller, K., Kvich, Lasse Andersson, Christensen, Mads Holm, Fritz, Blaine Gabriel, Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2024, (E-pub ahead of print) In: APMIS.Research output: Contribution to journal › Journal article › peer-review
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Silver against Pseudomonas aeruginosa biofilms
Bjarnsholt, Thomas, Kirketerp-Møller, K., Kristiansen, S., Phipps, R., Nielsen, A. K., Jensen, Peter Østrup, Høiby, Niels & Givskov, Michael, 2007, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 115, 8, p. 921-8 8 p.Research output: Contribution to journal › Journal article › peer-review
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Should standardized susceptibility testing for microbial biofilms be introduced in clinical practice?
Coenye, T., Goeres, D., Van Bambeke, F. & Bjarnsholt, Thomas, 2018, In: Clinical Microbiology and Infection. 24, 6, p. 570–572 3 p.Research output: Contribution to journal › Letter › peer-review
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Shotgun sequencing of clinical biofilm following scanning electron microscopy identifies bacterial community composition
Fritz, Blaine Gabriel, Stavnsbjerg, Camilla, Markvart, Merete, Damgaard, P. D. B., Nielsen, Sofie Holtsmark, Bjørndal, Lars, Qvortrup, Klaus & Bjarnsholt, Thomas, 2019, In: Pathogens and Disease. 77, 1, 7 p., ftz013.Research output: Contribution to journal › Journal article › peer-review
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Shaping the growth behaviour of biofilms initiated from bacterial aggregates
Melaugh, G., Hutchison, J., Kragh, K. N., Irie, Y., Roberts, A., Bjarnsholt, Thomas, Diggle, S. P., Gordon, V. D. & Allen, R. J., 2 Mar 2016, In: P L o S One. 11, 3, 18 p., e0149683.Research output: Contribution to journal › Journal article › peer-review
Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector
Rasmussen, T. B., Bjarnsholt, Thomas, Skindersoe, M. E., Hentzer, M., Kristoffersen, P., Köte, M., Nielsen, J., Eberl, L. & Givskov, M., 2005, In: Journal of Bacteriology. 187, 5, p. 1799-814 15 p.Research output: Contribution to journal › Journal article › peer-review
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Samspillet mellem mikrobiota og immunsystemet ved kolorektal cancer
Raskov, H., Bjarnsholt, Thomas, Alamili, M., Kragh, K. N. & Gögenur, Ismail, 5 Nov 2018, In: Ugeskrift for Laeger. 180, 45, V04180253.Research output: Contribution to journal › Journal article › peer-review
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Sampling challenges in diagnosis of chronic bacterial infections
Jakobsen, Tim Holm, Xu, Y., Bay, Lene, Schønheyder, H. C., Jakobsen, T., Bjarnsholt, Thomas & Thomsen, T. R., 2021, In: Journal of Medical Microbiology. 70, 3Research output: Contribution to journal › Review › peer-review
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Role of multicellular aggregates in biofilm formation
Kragh, K. N., Hutchison, J. B., Melaugh, G., Rodesney, C., Roberts, A. E. L., Irie, Y., Jensen, Peter Østrup, Diggle, S. P., Allen, R. J., Gordon, V. & Bjarnsholt, Thomas, 22 Mar 2016, In: mBio. 7, 2, 11 p., e00237-16.Research output: Contribution to journal › Journal article › peer-review
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Risk factors for chronic biofilm-related infection associated with implanted medical devices
Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Clinical Microbiology and Infection. 26, 8, p. 1034-1038Research output: Contribution to journal › Review › peer-review
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Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction
Bjarnsholt, Thomas, Jensen, Peter Østrup & Alhede, M., 2019, In: Pathogens and Disease. 77, 5, ftz052.Research output: Contribution to journal › Journal article › peer-review
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Rethinking the Inoculum Used in Animal Models of Implant-Associated Osteomyelitis – The Formation and Application of Bacterial Aggregates
Hartmann, Katrine Top, Nielsen, R. L., Mikkelsen, F. C., Ingmer, Hanne, Kvich, Lasse Andersson, Aalbæk, Bent, Odgaard, Anders, Jensen, Henrik Elvang, Lichtenberg, Mads, Bjarnsholt, Thomas & Jensen, Louise Kruse, 2023, p. 59. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Relative contribution of Prevotella intermedia and Pseudomonas aeruginosa to lung pathology in airways of patients with cystic fibrosis
Ulrich, M., Beer, I., Braitmaier, P., Dierkes, M., Kummer, F., Krismer, B., Schumacher, U., Gräpler-Mainka, U., Riethmüller, J., Jensen, Peter Østrup, Bjarnsholt, Thomas, Høiby, Niels, Bellon, G. & Döring, G., 1 Nov 2010, In: Thorax. 65, 11, p. 978-984 7 p.Research output: Contribution to journal › Journal article › peer-review
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Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment
Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.Research output: Contribution to journal › Letter › peer-review
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Reduced Skin Microbiome Diversity in Infancy Is Associated with Increased Risk of Atopic Dermatitis in High-Risk Children
Halling, A. S., Fritz, Blaine Gabriel, Gerner, T., Rinnov, M. R., Bay, Lene, Knudgaard, M. H., Ravn, N. H., Trautner, S., Ruge, I. F., Olesen, C., Díiaz-Pinées Cort, I., Skov, Lone, Sørensen, N., Møller Rønnstad, A. T., Thomsen, Simon Francis, Egeberg, Alexander, Jakasa, I., Kezic, S., Bjarnsholt, Thomas & Thyssen, Jacob Pontoppidan, 2023, In: Journal of Investigative Dermatology. 143, 10, p. 2030-2038 15 p.Research output: Contribution to journal › Journal article › peer-review
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Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?
Jensen, Ramon Gordon, Johansen, Helle Krogh, Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R. & Homøe, Preben, Jul 2017, In: European Archives of Oto-Rhino-Laryngology. 274, 7, p. 2741-2747 7 p.Research output: Contribution to journal › Journal article › peer-review
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Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa
Jensen, Peter Østrup, Bjarnsholt, Thomas, Phipps, R., Rasmussen, T. B., Calum, H., Christoffersen, L., Moser, C., Williams, P., Pressler, T., Givskov, Michael & Høiby, Niels, 2007, In: Microbiology. 153, Pt 5, p. 1329-38 9 p.Research output: Contribution to journal › Journal article › peer-review
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Rapid identification of Stenotrophomonas maltophilia by peptide nucleic acid fluorescence in situ hybridization
Knudsen, N. R., Rasmussen, A. K. I., Fiandaca, M. J., Kragh, K. N., Bjarnsholt, Thomas, Høiby, Niels, Stender, H. & Guardabassi, Luca, 2014, In: New Microbes and New Infections. 2, 3, p. 79-81 3 p.Research output: Contribution to journal › Journal article › peer-review
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RE-SENSITIZATION OF ANOXIC PSEUDOMONAS AERUGINOSA BIOFILMS WITH RE-OXYGENATION USING HYPERBARIC OXYGEN TREATMENT
Kolpen, Mette, Mousavi, N., Sams, T., Kragh, K. N., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, P. O., Oct 2015, In: Pediatric Pulmonology. 50, S41, p. 312-312 1 p., 322.Research output: Contribution to journal › Conference abstract in journal › peer-review
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Quorum-sensing-regulated virulence factors in Pseudomonas aeruginosa are toxic to Lucilia sericata maggots
Andersen, A. S., Joergensen, B., Bjarnsholt, Thomas, Johansen, H., Karlsmark, T., Givskov, Michael, Krogfelt, K. A., Andersen, A. S., Jørgensen, B., Bjarnsholt, T., Johansen, H., Karlsmark, Tonny, Givskov, M. & Krogfelt, K. A., 1 Feb 2010, In: Microbiology. 156, Pt 2, p. 400-7 8 p.Research output: Contribution to journal › Journal article › peer-review
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Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens
Bjarnsholt, Thomas & Givskov, M. C., 29 Jul 2007, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 362, 1483, p. 1213-22 10 p.Research output: Contribution to journal › Journal article › peer-review
Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens
Bjarnsholt, Thomas & Givskov, M., 2007, In: Philosophical Transactions of the Royal Society of London. Biological Sciences. 362, 1483, p. 1213-22 9 p.Research output: Contribution to journal › Journal article › peer-review
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Quorum sensing regulation in Aeromonas hydrophila
Garde, C., Bjarnsholt, Thomas, Givskov, Michael, Jakobsen, Tim Holm, Hentzer, M., Claussen, A., Sneppen, K., Ferkinghoff-Borg, J. & Sams, T., 2010, In: Journal of Molecular Biology. 396, 4, p. 849-57 9 p.Research output: Contribution to journal › Journal article › peer-review
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Quorum sensing inhibitory drugs as next generation antimicrobials: worth the effort?
Bjarnsholt, Thomas & Givskov, Michael, 2008, In: Current Infectious Disease Reports. 10, 1, p. 22-28 7 p.Research output: Contribution to journal › Journal article › peer-review
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Quorum sensing inhibitors disable bacterial biofilms.
Bjarnsholt, Thomas, Tolker-Nielsen, Tim & Givskov, Michael, 2011, Emerging trends in in antibacterial discovery.. Miller, A. A. & Miller, P. F. (eds.). 1 ed. Norvich UK: HorizonBioscience, p. 211-224 14 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Quorum sensing antagonism from marine organisms
Skindersoe, M. E., Ettinger-Epstein, P., Rasmussen, T. B., Bjarnsholt, Thomas, de Nys, R. & Givskov, Michael, 2007, In: Marine Biotechnology. 10, 1, p. 56-63 7 p.Research output: Contribution to journal › Journal article › peer-review
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Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients
Bjarnsholt, Thomas, Jensen, Peter Østrup, Jakobsen, Tim Holm, Phipps, R., Nielsen, A. K., Rybtke, Morten Levin, Tolker-Nielsen, Tim, Givskov, Michael, Høiby, Niels, Ciofu, Oana & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 1 Jan 2010, In: PLoS ONE. 5, 4, p. e10115Research output: Contribution to journal › Journal article › peer-review
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Quantitative analysis of the cellular inflammatory response against biofilm bacteria in chronic wounds
Fazli, M., Bjarnsholt, Thomas, Kirketerp-Møller, K., Jørgensen, A., Andersen, C. B., Givskov, Michael & Tolker-Nielsen, Tim, 2011, In: Wound Repair and Regeneration. 19, 3, p. 387-91 5 p.Research output: Contribution to journal › Journal article › peer-review
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Qualitative and quantitative determination of quorum sensing inhibition in vitro
Jakobsen, Tim Holm, van Gennip, M., Hultqvist, Louise Dahl, Bjarnsholt, Thomas & Givskov, Michael, 1 Jan 2011, In: Methods in Molecular Biology. 692, 3, p. 253-263 11 p.Research output: Contribution to journal › Journal article › peer-review
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Qualitative and Quantitative Determination of Quorum Sensing Inhibition In Vitro
Jakobsen, Tim Holm, Alhede, M., Hultqvist, Louise Dahl, Bjarnsholt, Thomas & Givskov, Michael, 2018, Quorum Sensing: Methods and Protocols. Springer, Vol. 1673. p. 275-285 11 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Pseudomonas aeruginosa transcriptome during human infection
Cornforth, D. M., Dees, J. L., Ibberson, C. B., Huse, H. K., Mathiesen, I. H., Kirketerp-Møller, K., Wolcott, R. D., Rumbaugh, K. P., Bjarnsholt, Thomas & Whiteley, M., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 22, p. E5125-E5134Research output: Contribution to journal › Journal article › peer-review
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Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent
Bjarnsholt, Thomas, Jensen, P. Ø., Burmølle, M., Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, C., Molin, S., Høiby, Niels & Givskov, M. C., 1 Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.Research output: Contribution to journal › Journal article › peer-review
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Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients
Bjarnsholt, Thomas, Jensen, Peter Østrup, Fiandaca, M. J., Pedersen, J., Hansen, C. R., Andersen, C. B., Pressler, T., Givskov, Michael & Høiby, Niels, 1 Jun 2009, In: Pediatric Pulmonology. 44, 6, p. 547-58 12 p.Research output: Contribution to journal › Journal article › peer-review
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Pseudomonas aeruginosa biofilms in cystic fibrosis
Høiby, Niels, Ciofu, Oana & Bjarnsholt, Thomas, 1 Nov 2010, In: Future Microbiology. 5, p. 1663-74 12 p.Research output: Contribution to journal › Review › peer-review
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Pseudomonas aeruginosa biofilm infection in the smaller airways of BALB/c mice exacerbates pulmonary inflammation.
Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model
Trøstrup, H., Thomsen, K., Christophersen, L. J., Hougen, H. P., Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.Research output: Contribution to journal › Journal article › peer-review
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Pseudomonas aeruginosa Biofilms: Mechanisms of Immune Evasion
Alhede, M., Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., 2014, In: Advances in Applied Microbiology. 86, p. 1-40 40 p.Research output: Contribution to journal › Journal article
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Protocol to assess metabolic activity of Pseudomonas aeruginosa by measuring heat flow using isothermal calorimetry
Beilharz, K., Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim, Bjarnsholt, Thomas & Lichtenberg, Mads, 2023, In: STAR Protocols. 4, 2, 102269.Research output: Contribution to journal › Journal article › peer-review
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Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: protocol for a randomised, double-blind, placebo-controlled trial (The BREAST-AB trial)
Hemmingsen, M. N., Larsen, A., Weltz, T. K., Ørholt, M., Wiberg, S., Bennedsen, A. K., Bille, C., Carstensen, L. F., Jensen, L. T., Bredgaard, R., Koudahl, V., Schmidt, Volker-Jürgen, Vester-Glowinski, Peter Viktor, Hølmich, Lisbet Rosenkrantz, Sørensen, Søren Johannes, Bjarnsholt, Thomas, Damsgaard, Tine M Engberg & Herly, Mikkel, 2022, In: BMJ Open. 12, 9, p. e058697Research output: Contribution to journal › Journal article › peer-review
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Process for the manufacture of ajoene derivatives
Bjarnsholt, Thomas, Høiby, Niels, Jensen, Peter Østrup, Phipps, R., Shanmugham, Meenakshi, S., Alhede, M., Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Tanner, D., Larsen, Thomas, O. & Givskov, Michael, 14 Jun 2012, IPC No. C07C 323/ 65 A I, Patent No. WO2012076016, Priority date 8 Dec 2010, Priority No. EP20100194154Research output: Patent
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Probiotics in hidradenitis suppurativa: a potential treatment option?
Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Clinical and Experimental Dermatology. 47, 1, p. 139-141 2 p.Research output: Contribution to journal › Comment/debate
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Prevention of biofilm formation in the soft tissue filler Aquamid
Er, Ö., Kühl, Michael, Tvede, M., Høiby, Niels, Nielsen, A. K. & Bjarnsholt, Thomas, 2011.Research output: Contribution to conference › Poster › Research › peer-review
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Prevalence of biofilms in acute infections challenges a longstanding paradigm
Kolpen, M., Jensen, Peter Østrup, Faurholt-Jepsen, D. & Bjarnsholt, Thomas, 2022, In: Biofilm. 4, 100080.Research output: Contribution to journal › Journal article › peer-review
ID: 9755066
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
Research output: Contribution to journal › Journal article › peer-review
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
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