Thomas Bjarnsholt
Professor
Bacteriology
Nørre Allé 14
2200 København N
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Early implant-associated osteomyelitis results in a peri-implanted bacterial reservoir
Jensen, Louise Kruse, Koch, J., Aalbæk, Bent, Moodley, Arshnee, Bjarnsholt, Thomas, Kragh, K. N., Petersen, A. & Jensen, Henrik Elvang, Jan 2017, In: APMIS - Journal of Pathology, Microbiology and Immunology. 125, 1, p. 38-45 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ecology of biofilms in chronic wounds
Bjarnsholt, Thomas & Givskov, M., 2010, WHS yearbook 2010.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Editorial: The complexity of microbial biofilm research-an introduction to the third thematic issue on biofilms
Coenye, T. & Bjarnsholt, Thomas, Oct 2016, In: Pathogens and Disease. 74, 7, 2 p., ftw053.Research output: Contribution to journal › Editorial › Research › peer-review
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Effects of Photoactivated Titanium Dioxide Nanopowders and Coating on Planktonic and Biofilm Growth of Pseudomonas aeruginosa
Polo, A., Diamanti, M. V., Bjarnsholt, Thomas, Høiby, Niels, Villa, F., Pedeferri, M. P. & Cappitelli, F., 25 Jul 2011, In: Photochemistry and Photobiology.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa
Skindersoe, M. E., Alhede, M., Phipps, R., Yang, L., Jensen, P. O., Rasmussen, T. B., Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 1 Oct 2008, In: Antimicrobial Agents and Chemotherapy. 52, 10, p. 3648-63 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endolysin Inhibits Skin Colonization by Patient-Derived Staphylococcus Aureus and Malignant T-Cell Activation in Cutaneous T-Cell Lymphoma
Pallesen, E. M. H., Gluud, M., Vadivel, C. K., Buus, T. B., de Rooij, B., Zeng, Z., Ahmad, S., Willerslev-Olsen, A., Röhrig, C., Kamstrup, M. R., Bay, L., Lindahl, L., Krejsgaard, T., Geisler, C., Bonefeld, C. M., Iversen, L., Woetmann, A., Koralov, S. B., Bjarnsholt, T., Frieling, J. & 2 others, , 2023, In: Journal of Investigative Dermatology. 143, 9, p. 1757-1769 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Eradication of biofilms on tympanostomy tubes with acetic acid treatment: an in vitro study
Kjeldsen, M., Homøe, Preben, Nielsen, Anne Kirstine, Crone, S., Nørskov Kragh, K. & Bjarnsholt, Thomas, 2020, In: APMIS. 128, 6, p. 445-450Research output: Contribution to journal › Journal article › Research › peer-review
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Establishing a consensus on wound infection definitions
Haesler, E., Swanson, T., Ousey, K., Larsen, D., Carville, K., Bjarnsholt, Thomas & Haesler, P., 2022, In: Journal of Wound Care. 31, S12, p. S48-S59Research output: Contribution to journal › Journal article › Research › peer-review
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Exhaled breath analysis using electronic nose in cystic fibrosis and primary ciliary dyskinesia patients with chronic pulmonary infections
Joensen, O., Paff, T., Haarman, E. G., Skovgaard, I. M., Jensen, Peter Østrup, Bjarnsholt, Thomas & Nielsen, Kim G., 2014, In: PLOS ONE. 9, 12, p. 1-15 15 p., e115584.Research output: Contribution to journal › Journal article › Research › peer-review
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Extensive debridement is fundamental for the success of an absorbable gentamicin loaded bio-composite
Jensen, Louise Kruse, Blirup-Plum, Sophie Amalie, Aalbæk, Bent, Bjarnsholt, Thomas, Kragh, K. N., Gottlieb, H., Bue, M. & Jensen, Henrik Elvang, 12 Sep 2019.Research output: Contribution to conference › Conference abstract for conference › Communication
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Extreme high local intra-operative gentamicin concentrations are needed to prevent biofilm formation in-vivo
Jensen, Louise Kruse, Bjarnsholt, Thomas, Henriksen, Nicole Lind, Kragh, K. N. & Jensen, Henrik Elvang, 6 Sep 2018.Research output: Contribution to conference › Conference abstract for conference › Communication
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Fluorescence in situ hybridization for the tissue detection of bacterial pathogens associated with porcine infections.
Jensen, Henrik Elvang, Jensen, Louise Kruse, Barington, Kristiane, Pors, S. E., Bjarnsholt, Thomas & Boye, M., 2015, In: Methods in Molecular Biology. 1247, p. 219-134 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa
Jakobsen, Tim Holm, Bragason, S. K., Phipps, R. K., Hultqvist, Louise Dahl, van Gennip, M., Alhede, M., Skindersoe, M., Larsen, T. O., Høiby, Niels, Bjarnsholt, Thomas & Givskov, Michael, 2012, In: Applied and Environmental Microbiology. 78, 7, p. 2410-2421 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth
Høiby, Niels, Henneberg, K. Å., Wang, H., Stavnsbjerg, Camilla, Bjarnsholt, Thomas, Ciofu, Oana, Johansen, U. R. & Sams, T., 2019, In: International Journal of Antimicrobial Agents. 53, 5, p. 564-573Research output: Contribution to journal › Journal article › Research › peer-review
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Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms
Jensen, Peter Østrup, Briales, A., Brochmann, R. P., Wang, H., Kragh, K. N., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Ciofu, Oana, 2014, In: Pathogens and Disease. 70, 3, p. 440-443 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.
Høiby, Niels, Johansen, Helle Krogh, Ciofu, Oana, Jensen, Peter Østrup, Bjarnsholt, Thomas & Givskov, Michael, 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudo-monas aeruginosa infections.
Bjarnsholt, Thomas, Jensen, P. Ø., Rasmussen, T. B., Christoffersen, L., Calum, Henrik Pierre, Hentzer, M., Hougen, H. P., Rygaard, J., Moser, Claus Ernst, Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: F E M S Microbiology. 151, p. 3873-3880 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections
Bjarnsholt, Thomas, Jensen, P. Ø., Rasmussen, T. B., Christophersen, L., Calum, H., Hentzer, M., Hougen, H., Rygaard, J., Moser, C., Eberl, L., Høiby, N. & Givskov, M., 2005, In: Microbiology. 151, Pt 12, p. 3873-80 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections
Bjarnsholt, Thomas, Jensen, P. Ø., Rasmussen, T. B., Christophersen, L., Calum, H., Hentzer, M., Hougen, H. P., Rygaard, J., Moser, C., Eberl, L., Høiby, Niels & Givskov, M. C., 1 Dec 2005, In: Microbiology. 151, Pt 12, p. 3873-80 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic adaptation of Pseudomonas aeruginosa during chronic lung infection of patients with cystic fibrosis: strong and weak mutators with heterogeneous genetic backgrounds emerge in mucA and/or lasR mutants
Ciofu, Oana, Mandsberg, L. F., Bjarnsholt, Thomas, Wassermann, T. & Høiby, Niels, 2010, In: Microbiology. 156, p. 1108-1119 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HUMAN SKIN MICROORGANISMS ARE DISTRIBUTED IN BIOFILM AGGREGATES AT WOUND EDGES
Bay, Lene, Agren, M. S., Poulsen, Steen Seier, Ghathian, K. S. A., Calum, H. & Bjarnsholt, Thomas, 2015, In: Wound Repair and Regeneration. 23, 4, p. A3-A3 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Haematoxylin and eosin staining identifies medium to large bacterial aggregates with a reliable specificity: A comparative analysis of follicular bacterial aggregates in axillary biopsies using peptide nucleic acid-fluorescence in situ hybridization and haematoxylin and eosin staining
Ring, H. C., Riis, P. T., Bay, Lene, Kallenbach, K., Bjarnsholt, Thomas & Jemec, Gregor, Oct 2017, In: Experimental Dermatology. 26, 10, p. 943-945Research output: Contribution to journal › Letter › Research › peer-review
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Har ny teknologi overflødiggjort Grams farvemetode? Dansk Selskab for Klinisk Mikrobiologi
Johansen, Helle Krogh, Bjarnsholt, Thomas, Høiby, Niels & Dansk Selskab for Klinisk Mikrobiologi, D. S. F. K. M., 17 Mar 2008, In: Ugeskrift for læger. 170, 12, p. 1041Research output: Contribution to journal › Journal article › Research › peer-review
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Heading for centennial anniversary and beyond
Norrild, B., Ralfkiaer, E., Bjarnsholt, Thomas & Jensen, Peter Østrup, Dec 2017, In: APMIS. 125, 12, p. 1133-1133Research output: Contribution to journal › Editorial › Research
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Histologic changes and gene expression patterns in biopsy specimens from bacteria-inoculated and noninoculated excisional body and limb wounds in horses healing by second intention
Jørgensen, Elin , Hjerpe, F. B., Hougen, H. P., Bjarnsholt, Thomas, Berg, Lise Charlotte & Jacobsen, Stine, 2020, In: American Journal of Veterinary Research. 81, 3, p. 276-284 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin
Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients
Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664Research output: Contribution to journal › Journal article › Research › peer-review
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IWII Wound Infection in Clinical Practice consensus document: 2022 update
Swanson, T., Ousey, K., Haesler, E., Bjarnsholt, Thomas, Carville, K., Idensohn, P., Kalan, L., Keast, D. H., Larsen, D., Percival, S., Schultz, G., Sussman, G., Waters, N. & Weir, D., 2022, In: Journal of Wound Care. 31, S12, p. S10-S21Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of pathogenic microorganisms directly from positive blood vials by matrix-assisted laser desorption/ionization time of flight mass spectrometry
Nonnemann, B., Tvede, M. & Bjarnsholt, Thomas, 18 Jan 2013, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 121, 9, p. 871-877 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Imaging N-acyl homoserine lactone quorum sensing in vivo
Hultqvist, Louise Dahl, Alhede, M., Jakobsen, Tim Holm, Givskov, Michael & Bjarnsholt, Thomas, 2018, Quorum Sensing: Methods and Protocols. Leoni, L. & Rampion, G. (eds.). Humana Press, Vol. 1673. p. 203-212 10 p. (Methods in Molecular Biology; No. 1673).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Imaging N-acyl homoserine lactone quorum sensing in vivo
Hultqvist, Louise Dahl, van Gennip, M., Jakobsen, Tim Holm, Givskov, Michael & Bjarnsholt, Thomas, 1 Jan 2011, In: Methods in Molecular Biology. 692, 2, p. 147-157 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model
Hultqvist, Louise Dahl, Moser, C., Jensen, Peter Østrup, Rasmussen, T. B., Christophersen, L., Kjelleberg, S., Kumar, N., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2007, In: Microbiology. 153, Pt 7, p. 2312-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Implants induce a new niche for microbiomes
Jakobsen, Tim Holm, Eickhardt, S. R., Gheorghe, Alexandra Gabriella, Stenqvist, C., Sønderholm, M., Stavnsberg, C., Jensen, Peter Østrup, Odgaard, Anders, Whiteley, M., Moser, Claus Ernst, Hvolris, J., Hougen, H. P. & Bjarnsholt, Thomas, 1 Aug 2018, In: APMIS - Journal of Pathology, Microbiology and Immunology. 126, 8, p. 685-692 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air
Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-Jepsen, Daniel, Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.Research output: Contribution to journal › Journal article › Research › peer-review
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In Situ Monitoring of the Antibacterial Activity of a Copper-Silver Alloy Using Confocal Laser Scanning Microscopy and pH Microsensors
Ciacotich, N., Kragh, K. N., Lichtenberg, Mads, Tesdorpf, J. E., Bjarnsholt, Thomas & Gram, L., 2019, In: Global Challenges. 3, 11, 9 p., 1900044.Research output: Contribution to journal › Journal article › Research › peer-review
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In memoriam-Mark E. Shirtliff (1969-2018)
Coenye, T., Bjarnsholt, Thomas, Stoodley, P. & Rumbaugh, K., 2018, In: Pathogens and Disease. 76, 7, fty068.Research output: Contribution to journal › Editorial › Research
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In silico analyses of metagenomes from human atherosclerotic plaque samples
Mitra, S., Drautz-Moses, D. I., Alhede, M., Maw, M. T., Liu, Y., Purbojati, R. W., Yap, Z. H., Kushwaha, K. K., Gheorghe, Alexandra Gabriella, Bjarnsholt, Thomas, Hansen, G. M., Sillesen, Henrik, Hougen, H. P., Hansen, Peter Riis, Yang, L., Tolker-Nielsen, Tim, Schuster, S. C. & Givskov, Michael, 2015, In: Microbiome. 3, p. 1-14 38.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect
Bjarnsholt, Thomas, van Gennip, M., Jakobsen, Tim Holm, Hultqvist, Louise Dahl, Jensen, Peter Østrup & Givskov, Michael, 2010, In: Nature Protocols (Print Edition). 5, 2, p. 282-93 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo gentamicin susceptibility test for prevention of bacterial biofilms in bone tissue and on implants
Jensen, Louise Kruse, Bjarnsholt, Thomas, Kragh, K. N., Aalbæk, Bent, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie, Pankoke, K., Petersen, A. & Jensen, Henrik Elvang, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, 10 p., e01889-18.Research output: Contribution to journal › Journal article › Research › peer-review
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Inactivation of Pseudomonas aeruginosa biofilm after ultraviolet light-emitting diode treatment: a comparative study between ultraviolet C and ultraviolet B
Argyraki, A., Markvart, Merete, Bjørndal, Lars, Bjarnsholt, Thomas & Petersen, P. M., 2017, In: Journal of Biomedical Optics. 22, 6, 7 p., 65004.Research output: Contribution to journal › Journal article › Research › peer-review
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Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes
Van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Phipps, R., Jensen, Peter Østrup, Christophersen, L., Pamp, S. J., Moser, C., Mikkelsen, P. J., Koh, A. Y., Tolker-Nielsen, Tim, Pier, G. B., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Jul 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 7, p. 537-46 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incidence of Propionibacterium acnes in initially culture-negative thioglycollate broths: a prospective cohort study at a Danish University Hospital
Kvich, Lasse Andersson, Jensen, Peter Østrup, Justesen, U. S. & Bjarnsholt, Thomas, Nov 2016, In: Clinical Microbiology and Infection. 22, 11, p. 941-945Research output: Contribution to journal › Journal article › Research › peer-review
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Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions
Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased severity of chronic Pseudomonas aeruginosa biofilm infection in the smaller airways of BALB/c mice
Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Increased severity of chronic Pseuomonas aeruginosa biofilm infection in the smaller airways of BALB/C mice
Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 0 p.Research output: Contribution to conference › Poster › Research › peer-review
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Inflammation in Achromobacter xylosoxidans infected cystic fibrosis patients
Hansen, C. R., Pressler, T., Nielsen, K. G., Jensen, Peter Østrup, Bjarnsholt, Thomas & Høiby, Niels, 1 Jan 2010, In: Journal of Cystic Fibrosis. 9, 1, p. 51-58 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of Pseudomonas aeruginosa quorum sensing by chemical induction of the MexEF-oprN efflux pump
Kristensen, Rasmus, Andersen, Jens Bo, Rybtke, Morten Levin, Jansen, C. U., Fritz, Blaine Gabriel, Kiilerich, R. O., Uhd, J., Bjarnsholt, Thomas, Qvortrup, K., Tolker-Nielsen, Tim, Givskov, Michael & Jakobsen, Tim Holm, 2024, In: Antimicrobial Agents and Chemotherapy. 68, 2Research output: Contribution to journal › Journal article › Research › peer-review
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Injection site microflora in persons with diabetes: why needle reuse is not associated with increased infections?
Wareham-Mathiassen, S., Bay, Lene, Glenting, V. P., Fatima, N., Bengtsson, H. & Bjarnsholt, Thomas, 2022, In: APMIS. 130, 7, p. 404-416 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inoculation method could impact the outcome of microbiological experiments
Kragh, K. N., Alhede, M., Rybtke, Morten Levin, Stavnsbjerg, Camilla, Tolker-Nielsen, Tim, Whiteley, M. & Bjarnsholt, Thomas, 2018, In: Applied and Environmental Microbiology. 84, 5, 14 p., e02264-17.Research output: Contribution to journal › Journal article › Research › peer-review
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Inoculum Concentration Influences Pseudomonas aeruginosa Phenotype and Biofilm Architecture
Lichtenberg, Mads, Kvich, Lasse Andersson, Larsen, S. L. B., Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2022, In: Microbiology Spectrum. 10, 6Research output: Contribution to journal › Journal article › Research › peer-review
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Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo
van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Qvortrup, Klaus, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interactions in multispecies biofilms: do they actually matter?
Burmølle, Mette, Ren, D., Bjarnsholt, Thomas & Sørensen, Søren Johannes, 2014, In: Trends in Microbiology. 22, 2, p. 84-91 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control
Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 2010, In: Expert Reviews in Molecular Medicine. 12, p. e11 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interfering with bacterial gossip.
Bjarnsholt, Thomas, Tolker-Nielsen, Tim & Givskov, Michael, 2011, Biofilm perspectives: Biofilm highlight. Flemming, H-C., Wingender, J. & Szewzyk, U. (eds.). 1 ed. Berlin: Springer Publishing Company, p. 163-188 26 p. (Springer Series on Biofilms, Vol. 5).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin
Woetmann, Anders , Alhede, M., Dabelsteen, Sally, Bjarnsholt, Thomas, Rybtke, Morten Levin, Nastasi, C., Krejsgaard, T., Andersen, Mads Hald, Bonefeld, Charlotte Menne, Geisler, Carsten, Givskov, Michael & Ødum, Niels, 2018, In: OncoTarget. 9, 28, p. 19481-19489 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization
Liu, W., Røder, Henriette Lyng, Madsen, Jonas Stenløkke, Bjarnsholt, Thomas, Sørensen, Søren Johannes & Burmølle, Mette, 2016, In: Frontiers in Microbiology. 7, 8 p., 1366.Research output: Contribution to journal › Review › Research › peer-review
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Into the well—A close look at the complex structures of a microtiter biofilm and the crystal violet assay
Kragh, K. N., Alhede, M., Kvich, Lasse Andersson & Bjarnsholt, Thomas, 2019, In: Biofilm. 1, 9 p., 100006.Research output: Contribution to journal › Journal article › Research › peer-review
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Introduction to Biofilm Infections
Bjarnsholt, Thomas, 2010, Biofilm Infections. New YorkResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Introduction to biofilms
Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer New York, p. 1-9 9 p.Research output: Chapter in Book/Report/Conference proceeding › Preface/postscript › Research › peer-review
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Investigation of the mechanism and chemistry underlying Staphylococcus aureus' ability to inhibit Pseudomonas aeruginosa growth in vitro
Kvich, Lasse Andersson, Crone, S. G., Christensen, M. H., Lima, R. D. C. L., Alhede, M., Alhede, M., Stærk, Dan & Bjarnsholt, Thomas, 2022, In: Journal of Bacteriology. 204, 11, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Is pseudarthrosis after spinal instrumentation caused by a chronic infection?
Ohrt-Nissen, S., Fritz, Blaine Gabriel, Valentin, L., Kragh, K. N., Manniche, C., Dahl, B. & Bjarnsholt, Thomas, 2019, In: European Spine Journal. 28, p. 2996–3002Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetic Model for Signal Binding to the Quorum Sensing Regulator LasR
Claussen, A., Jakobsen, Tim Holm, Bjarnsholt, Thomas, Givskov, Michael, Welch, M., Ferkinghoff-Borg, J. & Sams, T., 2013, In: International Journal of Molecular Sciences (Online). 14, 7, p. 13360-76 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Maxillary Sinus Impaction of a Core Carrier Causing Sustained Apical Periodontitis, Sinusitis, and Nasal Stenosis: A 3-year Follow-up
Bjørndal, Lars, Amaloo, C., Markvart, Merete, Rud, V., Qvortrup, Klaus, Stavnsbjerg, Camilla & Bjarnsholt, Thomas, 18 Oct 2016, In: The Journal of Endodontics. 42, 12, p. 1851-1858 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Measuring enzymatic degradation of degradable starch microspheres using confocal laser scanning microscopy
Thaarup, Ida Clement, Gummesson, C. & Bjarnsholt, Thomas, 2021, In: Acta Biomaterialia. 131, p. 464-471Research output: Contribution to journal › Journal article › Research › peer-review
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Methods for dynamic investigations of surface-attached in vitro bacterial and fungal biofilms
Sternberg, C., Bjarnsholt, Thomas & Shirtliff, M., 2014, In: Methods in molecular biology (Clifton, N.J.). 1147, p. 3-22 20 p.Research output: Contribution to journal › Journal article › Research
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Methods to classify bacterial pathogens in cystic fibrosis
Bjarnsholt, Thomas, Nielsen, X. C., Johansen, U., Nørgaard, L. & Høiby, Niels, 2011, In: Methods in Molecular Biology. 742, p. 143-71 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial Primer: In vivo biofilm
Rumbaugh, K. P. & Bjarnsholt, Thomas, 2023, In: Microbiology (United Kingdom). 169, 12, 5 p., 001407.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial biofilms and adverse reactions to gel fillers used in cosmetic surgery
Alhede, M., Christensen, L. H. & Bjarnsholt, Thomas, 2015, In: Advances in Experimental Medicine and Biology. 831, p. 45-52 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial biofilms--the coming of age of a research field
Coenye, T., Van Dijck, P., Bjarnsholt, Thomas & Forsberg, A., Apr 2014, In: Pathogens and Disease. 70, 3, p. 203-4 2 p.Research output: Contribution to journal › Journal article › Research
- Published
Minimum information guideline for spectrophotometric and fluorometric methods to assess biofilm formation in microplates
Allkja, J., Bjarnsholt, Thomas, Coenye, T., Cos, P., Fallarero, A., Harrison, J. J., Lopes, S. P., Oliver, A., Pereira, M. O., Ramage, G., Shirtliff, M. E., Stoodley, P., Webb, J. S., Zaat, S. A. J., Goeres, D. M. & Azevedo, N. F., 2020, In: Biofilm. 2, 8 p., 100010.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Moderate to severe hidradenitis suppurativa patients do not have an altered bacterial composition in peripheral blood compared to healthy controls
Ring, H. C., Thorsen, Jonathan Jan Ilve, Saunte, Ditte Marie, Lilje, B., Bay, Lene, Theut Riis, P., Larsen, N., O'Brien Andersen, L., Vedel Nielsen, H., Miller, I. M., Bjarnsholt, Thomas, Fuursted, K. & Jemec, Gregor, 2018, In: Journal of the European Academy of Dermatology and Venereology. 32, 1, p. 125-128 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media
Homøe, Preben, Bjarnsholt, Thomas, Wessman, M., Sørensen, H. C. F. & Johansen, Helle Krogh, 1 Oct 2009, In: European Archives of Oto-Rhino-Laryngology. 266, 10, p. 1533-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Morphological evidence of biofilm in chronic obstructive sialadenitis
Schrøder, S. A., Eickhardt, S., Bjarnsholt, Thomas, Nørgaard, T. & Homøe, Preben, 2018, In: Journal of Laryngology and Otology. 132, 7, p. 611-614 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mucoid Pseudomonas aeruginosa Can Produce Calcium-Gelled Biofilms Independent of the Matrix Components Psl and CdrA
Jacobs, H. M., O'Neal, L., Lopatto, E., Wozniak, D. J., Bjarnsholt, Thomas & Parsek, M. R., 2022, In: Journal of Bacteriology. 204, 5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mucosal biofilm detection in chronic otitis media: a study of middle ear biopsies from Greenlandic patients
Wessman, M., Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R., Johansen, Helle Krogh & Homøe, Preben, May 2015, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 272, 5, p. 1079-1085 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection
Bohn, Y. T., Brandes, G., Rakhimova, E., Horatzek, S., Salunkhe, P., Munder, A., van Barneveld, A., Jordan, D., Bredenbruch, F., Häussler, S., Riedel, K., Eberl, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, C., Høiby, Niels, Tümmler, B. & Wiehlmann, L., 2008, In: Molecular Microbiology. 71, 3, p. 730-47 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitric oxide production by polymorphonuclear leukocytes in infected cystic fibrosis sputum consumes oxygen
Kolpen, Mette, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Rickelt, L. F., Kühl, Michael, Hempel, C., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Clinical and Experimental Immunology. 177, 1, p. 310–319 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitric oxide production by polymorphonuclear leukocytes in sputum from CF patients with chronic lung infection
Jensen, Peter Østrup, Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Pressler, T. & Høiby, Niels, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection
Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Kühl, M., Høiby, Niels & Jensen, Peter Østrup, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection
Kolpen, Mette, Bjarnsholt, Thomas, Moser, C., Hansen, C. R., Kühl, Michael, Høiby, Niels & Jensen, P. Ø., 2010, In: Journal of Cystic Fibrosis. Supplement 1, p. S49 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa
Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: PLOS ONE. 9, 1, p. e84353 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nonrandom distribution of Pseudomonas aeruginosa and Staphylococcus aureus in chronic wounds
Fazli, M., Bjarnsholt, Thomas, Kirketerp-Møller, K., Jørgensen, B., Andersen, A. S., Krogfelt, K. A., Givskov, Michael & Tolker-Nielsen, Tim, 2009, In: Journal of Clinical Microbiology. 47, 12, p. 4084-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal Skin Microbiota is Altered in Pre-clinical Hidradenitis Suppurativa
Ring, H. C., Bay, Lene, Kallenbach, K., Miller, I. M., Prens, E., Saunte, Ditte Marie, Bjarnsholt, Thomas & Jemec, Gregor, Feb 2017, In: Acta Dermato-Venereologica. 97, 2, p. 208-213Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel Targets for Treatment of Pseudomonas aeruginosa Biofilms
Alhede, M., Alhede, M. & Bjarnsholt, Thomas, 1 Jan 2014, Antibiofilm Agents. Rumbaugh, K. (ed.). Springer Publishing Company, Vol. 8. p. 257-272 16 p. (Springer Series on Biofilms, Vol. 8).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Novel experimental Pseudomonas aeruginosa infection model mimicking long-term host-pathogen interactions in cystic fibrosis.
Moser, Claus Ernst, van Gennip, M., Bjarnsholt, Thomas, Jensen, P. Ø., Lee, B., Hougen, H. P., Calum, Henrik Pierre, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis
Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response
Jensen, Louise Kruse, Koch, J., Dich-Jørgensen, K., Aalbæk, Bent, Petersen, A., Fuursted, K., Bjarnsholt, Thomas, Kragh, K. N., Tøtterup, M., Bue, M., Hanberg, P., Søballe, K., Heegaard, P. M. H. & Jensen, Henrik Elvang, 2017, In: Journal of Orthopaedic Research. 35, 10, p. 2211–2221Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Novel sampling technique maintaining the two-dimensional organization of microbes during cultivation from chronic wounds: The Imprint method
Iversen, A. K. S., Fritz, Blaine Gabriel, Hansen, M. J., Kirketerp-Møller, K., Jakobsen, Tim Holm, Bjarnsholt, Thomas & Lichtenberg, Mads, 2024, (E-pub ahead of print) In: APMIS.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM
Kolpen, M., Ravnholt, C., Qvist, T., Kragh, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Oxygen restriction generates difficult-to-culture p. Aeruginosa
Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, K. N., Kolpen, Mette, Sønderholm, M., Andersson, M., Koch, A., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PNA-based fluorescence in situ hybridization for identification of bacteria in clinical samples
Fazli, M., Bjarnsholt, Thomas, Høiby, Niels, Givskov, Michael & Tolker-Nielsen, Tim, 2014, In: Methods in Molecular Biology. 1211, p. 261-71 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathogenic CD8+ epidermis-resident memory T cells displace dendritic epidermal T cells in allergic dermatitis
Gadsbøll, Anne-Sofie Østergaard, Jee, Mia Hamilton, Funch, Anders Boutrup, Alhede, M., Mraz, Veronika, Weber, Julie Friis, Callender, L. A., Carroll, E. C., Bjarnsholt, Thomas, Woetmann, Anders , Ødum, Niels, Thomsen, Allan Randrup, Johansen, Jeanne Duus, Henson, S. M., Geisler, Carsten & Bonefeld, Charlotte Menne, 2020, In: The Journal of Investigative Dermatology. 140, 4, p. 806-815.e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathological and microbiological impact of a gentamicin-loaded biocomposite following limited or extensive debridement in a porcine model of osteomyelitis
Blirup-Plum, Sophie Amalie, Bjarnsholt, Thomas, Jensen, Henrik Elvang, Kragh, K. N., Aalbæk, Bent, Gottlieb, Hans, Bue, M. & Jensen, Louise Kruse, 2020, In: Bone and Joint Research. 9, 7, p. 394-401 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathology and biofilm formation in a porcine model of staphylococcal osteomyelitis
Johansen, L. K., Koch, J., Frees, Dorte, Aalbæk, Bent, Nielsen, O. L., Leifsson, Páll S., Iburg, T. M., Svalastoga, Eiliv Lars, Buelund, Lene Elisabeth, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Henrik Elvang, 2012, In: Journal of Comparative Pathology. 147, 2-3, p. 343-353 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptidoglycan-Binding Anchor Is a Pseudomonas aeruginosa OmpA Family Lipoprotein With Importance for Outer Membrane Vesicles, Biofilms, and the Periplasmic Shape
Paulsson, M., Kragh, K. N., Su, Y. C., Sandblad, L., Singh, B., Bjarnsholt, Thomas & Riesbeck, K., 2021, In: Frontiers in Microbiology. 12, 639582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phage inhibit pathogen dissemination by targeting bacterial migrants in a chronic infection model
Darch, S. E., Kragh, K. N., Abbott, E. A., Bjarnsholt, Thomas, Bull, J. J. & Whiteley, M., Mar 2017, In: mBio. 8, 2, 15 p., e00240-17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacokinetics of Locally Applied Antibiotic Prophylaxis for Implant-Based Breast Reconstruction
Hemmingsen, Mathilde Nejrup, Bennedsen, A. K., Kullab, R. B., Norlin, C. B., Ørholt, M., Larsen, A., Bue, M., Lichtenberg, Mads, Hertz, Frederik Boëtius, Damsgaard, T. E., Vester-Glowinski, Peter Viktor, Sørensen, Søren Johannes, Bjarnsholt, Thomas & Herly, Mikkel, 2023, In: JAMA network open. 6, 12, 11 p., E2348414.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phenotype of non-attached Pseudomonas aeruginosa microclonies resembles attached biofilm, including reversible antibiotic tolerance
Alhede, M., Qvortrup, K., Allesen-Holm, M., van Gennip, M., Christensen, L., Jensen, Peter Østrup, Nielsen, A., Tolker-Nielsen, T., Høiby, Niels, Givskov, M. C. & Bjarnsholt, Thomas, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm
Alhede, M., Kragh, K. N., Qvortrup, Klaus, Allesen-Holm, M., van Gennip, M., Hultqvist, Louise Dahl, Jensen, Peter Østrup, Nielsen, A. K., Parsek, M., Wozniak, D., Molin, S., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2011, In: P L o S One. 6, 11, p. e27943Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9755066
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
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