Thomas Bjarnsholt
Professor
Bacteriology
Nørre Allé 14
2200 København N
- Published
Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo
van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Qvortrup, Klaus, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interactions in multispecies biofilms: do they actually matter?
Burmølle, Mette, Ren, D., Bjarnsholt, Thomas & Sørensen, Søren Johannes, 2014, In: Trends in Microbiology. 22, 2, p. 84-91 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control
Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 2010, In: Expert Reviews in Molecular Medicine. 12, p. e11 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interfering with bacterial gossip.
Bjarnsholt, Thomas, Tolker-Nielsen, Tim & Givskov, Michael, 2011, Biofilm perspectives: Biofilm highlight. Flemming, H-C., Wingender, J. & Szewzyk, U. (eds.). 1 ed. Berlin: Springer Publishing Company, p. 163-188 26 p. (Springer Series on Biofilms, Vol. 5).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin
Woetmann, Anders , Alhede, M., Dabelsteen, Sally, Bjarnsholt, Thomas, Rybtke, Morten Levin, Nastasi, C., Krejsgaard, T., Andersen, Mads Hald, Bonefeld, Charlotte Menne, Geisler, Carsten, Givskov, Michael & Ødum, Niels, 2018, In: OncoTarget. 9, 28, p. 19481-19489 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization
Liu, W., Røder, Henriette Lyng, Madsen, Jonas Stenløkke, Bjarnsholt, Thomas, Sørensen, Søren Johannes & Burmølle, Mette, 2016, In: Frontiers in Microbiology. 7, 8 p., 1366.Research output: Contribution to journal › Review › Research › peer-review
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Into the well—A close look at the complex structures of a microtiter biofilm and the crystal violet assay
Kragh, K. N., Alhede, M., Kvich, Lasse Andersson & Bjarnsholt, Thomas, 2019, In: Biofilm. 1, 9 p., 100006.Research output: Contribution to journal › Journal article › Research › peer-review
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Introduction to Biofilm Infections
Bjarnsholt, Thomas, 2010, Biofilm Infections. New YorkResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Introduction to biofilms
Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer New York, p. 1-9 9 p.Research output: Chapter in Book/Report/Conference proceeding › Preface/postscript › Research › peer-review
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Investigation of the mechanism and chemistry underlying Staphylococcus aureus' ability to inhibit Pseudomonas aeruginosa growth in vitro
Kvich, Lasse Andersson, Crone, S. G., Christensen, M. H., Lima, R. D. C. L., Alhede, M., Alhede, M., Stærk, Dan & Bjarnsholt, Thomas, 2022, In: Journal of Bacteriology. 204, 11, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Is pseudarthrosis after spinal instrumentation caused by a chronic infection?
Ohrt-Nissen, S., Fritz, Blaine Gabriel, Valentin, L., Kragh, K. N., Manniche, C., Dahl, B. & Bjarnsholt, Thomas, 2019, In: European Spine Journal. 28, p. 2996–3002Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetic Model for Signal Binding to the Quorum Sensing Regulator LasR
Claussen, A., Jakobsen, Tim Holm, Bjarnsholt, Thomas, Givskov, Michael, Welch, M., Ferkinghoff-Borg, J. & Sams, T., 2013, In: International Journal of Molecular Sciences (Online). 14, 7, p. 13360-76 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Maxillary Sinus Impaction of a Core Carrier Causing Sustained Apical Periodontitis, Sinusitis, and Nasal Stenosis: A 3-year Follow-up
Bjørndal, Lars, Amaloo, C., Markvart, Merete, Rud, V., Qvortrup, Klaus, Stavnsbjerg, Camilla & Bjarnsholt, Thomas, 18 Oct 2016, In: The Journal of Endodontics. 42, 12, p. 1851-1858 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Measuring enzymatic degradation of degradable starch microspheres using confocal laser scanning microscopy
Thaarup, Ida Clement, Gummesson, C. & Bjarnsholt, Thomas, 2021, In: Acta Biomaterialia. 131, p. 464-471Research output: Contribution to journal › Journal article › Research › peer-review
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Methods for dynamic investigations of surface-attached in vitro bacterial and fungal biofilms
Sternberg, C., Bjarnsholt, Thomas & Shirtliff, M., 2014, In: Methods in molecular biology (Clifton, N.J.). 1147, p. 3-22 20 p.Research output: Contribution to journal › Journal article › Research
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Methods to classify bacterial pathogens in cystic fibrosis
Bjarnsholt, Thomas, Nielsen, X. C., Johansen, U., Nørgaard, L. & Høiby, Niels, 2011, In: Methods in Molecular Biology. 742, p. 143-71 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial Primer: In vivo biofilm
Rumbaugh, K. P. & Bjarnsholt, Thomas, 2023, In: Microbiology (United Kingdom). 169, 12, 5 p., 001407.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial biofilms and adverse reactions to gel fillers used in cosmetic surgery
Alhede, M., Christensen, L. H. & Bjarnsholt, Thomas, 2015, In: Advances in Experimental Medicine and Biology. 831, p. 45-52 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial biofilms--the coming of age of a research field
Coenye, T., Van Dijck, P., Bjarnsholt, Thomas & Forsberg, A., Apr 2014, In: Pathogens and Disease. 70, 3, p. 203-4 2 p.Research output: Contribution to journal › Journal article › Research
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Minimum information guideline for spectrophotometric and fluorometric methods to assess biofilm formation in microplates
Allkja, J., Bjarnsholt, Thomas, Coenye, T., Cos, P., Fallarero, A., Harrison, J. J., Lopes, S. P., Oliver, A., Pereira, M. O., Ramage, G., Shirtliff, M. E., Stoodley, P., Webb, J. S., Zaat, S. A. J., Goeres, D. M. & Azevedo, N. F., 2020, In: Biofilm. 2, 8 p., 100010.Research output: Contribution to journal › Journal article › Research › peer-review
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Moderate to severe hidradenitis suppurativa patients do not have an altered bacterial composition in peripheral blood compared to healthy controls
Ring, H. C., Thorsen, Jonathan Jan Ilve, Saunte, Ditte Marie, Lilje, B., Bay, Lene, Theut Riis, P., Larsen, N., O'Brien Andersen, L., Vedel Nielsen, H., Miller, I. M., Bjarnsholt, Thomas, Fuursted, K. & Jemec, Gregor, 2018, In: Journal of the European Academy of Dermatology and Venereology. 32, 1, p. 125-128 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media
Homøe, Preben, Bjarnsholt, Thomas, Wessman, M., Sørensen, H. C. F. & Johansen, Helle Krogh, 1 Oct 2009, In: European Archives of Oto-Rhino-Laryngology. 266, 10, p. 1533-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Morphological evidence of biofilm in chronic obstructive sialadenitis
Schrøder, S. A., Eickhardt, S., Bjarnsholt, Thomas, Nørgaard, T. & Homøe, Preben, 2018, In: Journal of Laryngology and Otology. 132, 7, p. 611-614 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mucoid Pseudomonas aeruginosa Can Produce Calcium-Gelled Biofilms Independent of the Matrix Components Psl and CdrA
Jacobs, H. M., O'Neal, L., Lopatto, E., Wozniak, D. J., Bjarnsholt, Thomas & Parsek, M. R., 2022, In: Journal of Bacteriology. 204, 5Research output: Contribution to journal › Journal article › Research › peer-review
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Mucosal biofilm detection in chronic otitis media: a study of middle ear biopsies from Greenlandic patients
Wessman, M., Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R., Johansen, Helle Krogh & Homøe, Preben, May 2015, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 272, 5, p. 1079-1085 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection
Bohn, Y. T., Brandes, G., Rakhimova, E., Horatzek, S., Salunkhe, P., Munder, A., van Barneveld, A., Jordan, D., Bredenbruch, F., Häussler, S., Riedel, K., Eberl, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, C., Høiby, Niels, Tümmler, B. & Wiehlmann, L., 2008, In: Molecular Microbiology. 71, 3, p. 730-47 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nitric oxide production by polymorphonuclear leukocytes in infected cystic fibrosis sputum consumes oxygen
Kolpen, Mette, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Rickelt, L. F., Kühl, Michael, Hempel, C., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Clinical and Experimental Immunology. 177, 1, p. 310–319 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nitric oxide production by polymorphonuclear leukocytes in sputum from CF patients with chronic lung infection
Jensen, Peter Østrup, Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Pressler, T. & Høiby, Niels, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection
Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Kühl, M., Høiby, Niels & Jensen, Peter Østrup, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection
Kolpen, Mette, Bjarnsholt, Thomas, Moser, C., Hansen, C. R., Kühl, Michael, Høiby, Niels & Jensen, P. Ø., 2010, In: Journal of Cystic Fibrosis. Supplement 1, p. S49 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa
Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.Research output: Contribution to journal › Journal article › Research › peer-review
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: PLOS ONE. 9, 1, p. e84353 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonrandom distribution of Pseudomonas aeruginosa and Staphylococcus aureus in chronic wounds
Fazli, M., Bjarnsholt, Thomas, Kirketerp-Møller, K., Jørgensen, B., Andersen, A. S., Krogfelt, K. A., Givskov, Michael & Tolker-Nielsen, Tim, 2009, In: Journal of Clinical Microbiology. 47, 12, p. 4084-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Normal Skin Microbiota is Altered in Pre-clinical Hidradenitis Suppurativa
Ring, H. C., Bay, Lene, Kallenbach, K., Miller, I. M., Prens, E., Saunte, Ditte Marie, Bjarnsholt, Thomas & Jemec, Gregor, Feb 2017, In: Acta Dermato-Venereologica. 97, 2, p. 208-213Research output: Contribution to journal › Journal article › Research › peer-review
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Novel Targets for Treatment of Pseudomonas aeruginosa Biofilms
Alhede, M., Alhede, M. & Bjarnsholt, Thomas, 1 Jan 2014, Antibiofilm Agents. Rumbaugh, K. (ed.). Springer Publishing Company, Vol. 8. p. 257-272 16 p. (Springer Series on Biofilms, Vol. 8).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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Novel experimental Pseudomonas aeruginosa infection model mimicking long-term host-pathogen interactions in cystic fibrosis.
Moser, Claus Ernst, van Gennip, M., Bjarnsholt, Thomas, Jensen, P. Ø., Lee, B., Hougen, H. P., Calum, Henrik Pierre, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis
Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response
Jensen, Louise Kruse, Koch, J., Dich-Jørgensen, K., Aalbæk, Bent, Petersen, A., Fuursted, K., Bjarnsholt, Thomas, Kragh, K. N., Tøtterup, M., Bue, M., Hanberg, P., Søballe, K., Heegaard, P. M. H. & Jensen, Henrik Elvang, 2017, In: Journal of Orthopaedic Research. 35, 10, p. 2211–2221Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Novel sampling technique maintaining the two-dimensional organization of microbes during cultivation from chronic wounds: The Imprint method
Iversen, A. K. S., Fritz, Blaine Gabriel, Hansen, M. J., Kirketerp-Møller, K., Jakobsen, Tim Holm, Bjarnsholt, Thomas & Lichtenberg, Mads, 2024, (E-pub ahead of print) In: APMIS.Research output: Contribution to journal › Journal article › Research › peer-review
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O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM
Kolpen, M., Ravnholt, C., Qvist, T., Kragh, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Oxygen restriction generates difficult-to-culture p. Aeruginosa
Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, K. N., Kolpen, Mette, Sønderholm, M., Andersson, M., Koch, A., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.Research output: Contribution to journal › Journal article › Research › peer-review
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PNA-based fluorescence in situ hybridization for identification of bacteria in clinical samples
Fazli, M., Bjarnsholt, Thomas, Høiby, Niels, Givskov, Michael & Tolker-Nielsen, Tim, 2014, In: Methods in Molecular Biology. 1211, p. 261-71 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pathogenic CD8+ epidermis-resident memory T cells displace dendritic epidermal T cells in allergic dermatitis
Gadsbøll, Anne-Sofie Østergaard, Jee, Mia Hamilton, Funch, Anders Boutrup, Alhede, M., Mraz, Veronika, Weber, Julie Friis, Callender, L. A., Carroll, E. C., Bjarnsholt, Thomas, Woetmann, Anders , Ødum, Niels, Thomsen, Allan Randrup, Johansen, Jeanne Duus, Henson, S. M., Geisler, Carsten & Bonefeld, Charlotte Menne, 2020, In: The Journal of Investigative Dermatology. 140, 4, p. 806-815.e5Research output: Contribution to journal › Journal article › Research › peer-review
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Pathological and microbiological impact of a gentamicin-loaded biocomposite following limited or extensive debridement in a porcine model of osteomyelitis
Blirup-Plum, Sophie Amalie, Bjarnsholt, Thomas, Jensen, Henrik Elvang, Kragh, K. N., Aalbæk, Bent, Gottlieb, Hans, Bue, M. & Jensen, Louise Kruse, 2020, In: Bone and Joint Research. 9, 7, p. 394-401 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pathology and biofilm formation in a porcine model of staphylococcal osteomyelitis
Johansen, L. K., Koch, J., Frees, Dorte, Aalbæk, Bent, Nielsen, O. L., Leifsson, Páll S., Iburg, T. M., Svalastoga, Eiliv Lars, Buelund, Lene Elisabeth, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Henrik Elvang, 2012, In: Journal of Comparative Pathology. 147, 2-3, p. 343-353 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptidoglycan-Binding Anchor Is a Pseudomonas aeruginosa OmpA Family Lipoprotein With Importance for Outer Membrane Vesicles, Biofilms, and the Periplasmic Shape
Paulsson, M., Kragh, K. N., Su, Y. C., Sandblad, L., Singh, B., Bjarnsholt, Thomas & Riesbeck, K., 2021, In: Frontiers in Microbiology. 12, 639582.Research output: Contribution to journal › Journal article › Research › peer-review
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Phage inhibit pathogen dissemination by targeting bacterial migrants in a chronic infection model
Darch, S. E., Kragh, K. N., Abbott, E. A., Bjarnsholt, Thomas, Bull, J. J. & Whiteley, M., Mar 2017, In: mBio. 8, 2, 15 p., e00240-17.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacokinetics of Locally Applied Antibiotic Prophylaxis for Implant-Based Breast Reconstruction
Hemmingsen, Mathilde Nejrup, Bennedsen, A. K., Kullab, R. B., Norlin, C. B., Ørholt, M., Larsen, A., Bue, M., Lichtenberg, Mads, Hertz, Frederik Boëtius, Damsgaard, T. E., Vester-Glowinski, Peter Viktor, Sørensen, Søren Johannes, Bjarnsholt, Thomas & Herly, Mikkel, 2023, In: JAMA network open. 6, 12, 11 p., E2348414.Research output: Contribution to journal › Journal article › Research › peer-review
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Phenotype of non-attached Pseudomonas aeruginosa microclonies resembles attached biofilm, including reversible antibiotic tolerance
Alhede, M., Qvortrup, K., Allesen-Holm, M., van Gennip, M., Christensen, L., Jensen, Peter Østrup, Nielsen, A., Tolker-Nielsen, T., Høiby, Niels, Givskov, M. C. & Bjarnsholt, Thomas, 2010. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm
Alhede, M., Kragh, K. N., Qvortrup, Klaus, Allesen-Holm, M., van Gennip, M., Hultqvist, Louise Dahl, Jensen, Peter Østrup, Nielsen, A. K., Parsek, M., Wozniak, D., Molin, S., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2011, In: P L o S One. 6, 11, p. e27943Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9755066
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Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
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