Thomas Bjarnsholt

Thomas Bjarnsholt

Professor


  1. 2010
  2. Published

    Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

    Burmølle, Mette, Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.

    Research output: Contribution to journalReviewpeer-review

  3. Published

    Complete genomic sequence of the CF pathogene Achromobacter xylosoxidans and in vitro biofilm formation

    Jakobsen, T. H., Hansen, M., Kerpedjiev, P., Hansen, L., Jensen, Peter Østrup, Hansen, C. R., Qvortrup, K., Givskov, M., Burmølle, M., Sørensen, S. J., Høiby, Niels & Bjarnsholt, Thomas, 2010. 0 p.

    Research output: Contribution to conferencePaperResearchpeer-review

  4. Published

    Detection of microorganisms involved in airway infection of cystic fibrosis patients by standard culturing 6 molecular methods

    Rudkjøbing, V., Thomsen, T. R., Nielsen, P. H., Alhede, M., Johansen, U. R., Høiby, Niels & Bjarnsholt, Thomas, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  5. Published

    Ecology of biofilms in chronic wounds

    Bjarnsholt, Thomas & Givskov, M., 2010, WHS yearbook 2010.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  6. Published
  7. Published

    In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect

    Bjarnsholt, Thomas, van Gennip, M., Jakobsen, Tim Holm, Hultqvist, Louise Dahl, Jensen, Peter Østrup & Givskov, Michael, 2010, In: Nature Protocols (Print Edition). 5, 2, p. 282-93 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Increased severity of chronic Pseudomonas aeruginosa biofilm infection in the smaller airways of BALB/c mice

    Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  9. Published

    Increased severity of chronic Pseuomonas aeruginosa biofilm infection in the smaller airways of BALB/C mice

    Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 0 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  10. Published

    Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control

    Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 2010, In: Expert Reviews in Molecular Medicine. 12, p. e11 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Introduction to Biofilm Infections

    Bjarnsholt, Thomas, 2010, Biofilm Infections. New York

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  12. Published

    Nitric oxide production by polymorphonuclear leukocytes in sputum from CF patients with chronic lung infection

    Jensen, Peter Østrup, Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Pressler, T. & Høiby, Niels, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  13. Published

    Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection

    Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Kühl, M., Høiby, Niels & Jensen, Peter Østrup, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  14. Published

    Nitric oxide production by polymorphonuclear leukocytes in sputum from cystic fibrosis patients with chronic lung infection

    Kolpen, Mette, Bjarnsholt, Thomas, Moser, C., Hansen, C. R., Kühl, Michael, Høiby, Niels & Jensen, P. Ø., 2010, In: Journal of Cystic Fibrosis. Supplement 1, p. S49 1 p.

    Research output: Contribution to journalConference abstract in journal

  15. Published

    Phenotype of non-attached Pseudomonas aeruginosa microclonies resembles attached biofilm, including reversible antibiotic tolerance

    Alhede, M., Qvortrup, K., Allesen-Holm, M., van Gennip, M., Christensen, L., Jensen, Peter Østrup, Nielsen, A., Tolker-Nielsen, T., Høiby, Niels, Givskov, M. C. & Bjarnsholt, Thomas, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  16. Published

    Pseudomonas aeruginosa biofilm infection in the smaller airways of BALB/c mice exacerbates pulmonary inflammation.

    Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  17. Published

    Quorum sensing regulation in Aeromonas hydrophila

    Garde, C., Bjarnsholt, Thomas, Givskov, Michael, Jakobsen, Tim Holm, Hentzer, M., Claussen, A., Sneppen, K., Ferkinghoff-Borg, J. & Sams, T., 2010, In: Journal of Molecular Biology. 396, 4, p. 849-57 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Summary and Perspectives

    Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, 2010, Biofilm Infections. Bjarnsholt, T., Moser, C. E., Jensen, P. Ø. & Høiby, N. (eds.). 1st ed. New York. NY. US: Springer Science+Business Media, p. 291-293 3 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  19. Published

    Synergistic antimicrobial efficacy of furanone C30 and tobramycin against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model

    Christensen, L., van Gennip, M., Alhede, M., Kumar, N., Kjelleberg, S., Høiby, Niels, Bjarnsholt, Thomas & Givskov, M., 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  20. Published

    The bacteriology of chronic venous leg ulcer examined by culture-independent molecular methods

    Thomsen, T. R., Aasholm, M. S., Rudkjøbing, V. B., Saunders, A. M., Bjarnsholt, Thomas, Givskov, Michael, Kirketerp-Møller, K. & Nielsen, P. H., 2010, In: Wound Repair and Regeneration. 18, 1, p. 38-49 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    The immune system vs. Pseudomonas aeruginosa biofilms

    Jensen, Peter Østrup, Givskov, Michael, Bjarnsholt, Thomas & Moser, C., 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 292-305 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Visualization of in vivo biofilm developing on silicone implants and the interaction with the cellular response

    van Gennip, M., Christensen, L., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  23. Published

    Visualization of the in vivo interaction of a P. aeruginosa biofilm & the innate host cellular response

    van Gennip, M., Christensen, L. D., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  24. 2009
  25. Published

    Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa

    van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, H. P., Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media

    Homøe, Preben, Bjarnsholt, Thomas, Wessman, M., Sørensen, H. C. F. & Johansen, Helle Krogh, 1 Oct 2009, In: European Archives of Oto-Rhino-Laryngology. 266, 10, p. 1533-8 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes

    Van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Phipps, R., Jensen, Peter Østrup, Christophersen, L., Pamp, S. J., Moser, C., Mikkelsen, P. J., Koh, A. Y., Tolker-Nielsen, Tim, Pier, G. B., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Jul 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 7, p. 537-46 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients

    Bjarnsholt, Thomas, Jensen, Peter Østrup, Fiandaca, M. J., Pedersen, J., Hansen, C. R., Andersen, C. B., Pressler, T., Givskov, Michael & Høiby, Niels, 1 Jun 2009, In: Pediatric Pulmonology. 44, 6, p. 547-58 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis

    Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes

    Alhede, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Phipps, R. K., Moser, Claus Ernst, Christophersen, L., Hultqvist, Louise Dahl, van Gennip, M., Parsek, M., Høiby, Niels, Rasmussen, T. B. & Givskov, Michael, 2009, In: Microbiology. 155, 11, p. 3500-3508 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Computer-aided identification of recognized drugs as Pseudomonas aeruginosa quorum-sensing inhibitors

    Yang, L., Rybtke, Morten Levin, Jakobsen, Tim Holm, Hentzer, M., Bjarnsholt, Thomas, Givskov, Michael & Tolker-Nielsen, Tim, 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2432-43 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Detection of Bacteria by Fluorescence in Situ Hybridization in Culture-Negative Soft Tissue Filler Lesions

    Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Givskov, Michael, Janssen, M. & Christensen, L. H., 2009, In: Dermatologic Surgery. 35 Suppl 2, p. 1620-1624 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Nonrandom distribution of Pseudomonas aeruginosa and Staphylococcus aureus in chronic wounds

    Fazli, M., Bjarnsholt, Thomas, Kirketerp-Møller, K., Jørgensen, B., Andersen, A. S., Krogfelt, K. A., Givskov, Michael & Tolker-Nielsen, Tim, 2009, In: Journal of Clinical Microbiology. 47, 12, p. 4084-9 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Novel experimental Pseudomonas aeruginosa infection model mimicking long-term host-pathogen interactions in cystic fibrosis.

    Moser, Claus Ernst, van Gennip, M., Bjarnsholt, Thomas, Jensen, P. Ø., Lee, B., Hougen, H. P., Calum, Henrik Pierre, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, p. 95-107 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. 2008
  36. Published

    Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa

    Skindersoe, M. E., Alhede, M., Phipps, R., Yang, L., Jensen, P. O., Rasmussen, T. B., Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 1 Oct 2008, In: Antimicrobial Agents and Chemotherapy. 52, 10, p. 3648-63 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Distribution, organization, and ecology of bacteria in chronic wounds

    Kirketerp-Møller, K., Jensen, Peter Østrup, Fazli, M., Madsen, K. G., Pedersen, J., Moser, C., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Aug 2008, In: Journal of Clinical Microbiology. 46, 8, p. 2717-22 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Har ny teknologi overflødiggjort Grams farvemetode? Dansk Selskab for Klinisk Mikrobiologi

    Johansen, Helle Krogh, Bjarnsholt, Thomas, Høiby, Niels & Dansk Selskab for Klinisk Mikrobiologi, D. S. F. K. M., 17 Mar 2008, In: Ugeskrift for læger. 170, 12, p. 1041

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection

    Bohn, Y. T., Brandes, G., Rakhimova, E., Horatzek, S., Salunkhe, P., Munder, A., van Barneveld, A., Jordan, D., Bredenbruch, F., Häussler, S., Riedel, K., Eberl, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, C., Høiby, Niels, Tümmler, B. & Wiehlmann, L., 2008, In: Molecular Microbiology. 71, 3, p. 730-47 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Quorum sensing inhibitory drugs as next generation antimicrobials: worth the effort?

    Bjarnsholt, Thomas & Givskov, Michael, 2008, In: Current Infectious Disease Reports. 10, 1, p. 22-28 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    The Pseudomonas aeruginosa autoinducer dodecanoyl-homoserine lactone inhibits the putrescine synthesis in human cells

    Kristiansen, S., Bjarnsholt, Thomas, Adeltoft, D., Ifversen, P. & Givskov, Michael, 2008, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 116, 5, p. 361-371 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Thermal injury induces impaired function in polymorphonuclear neutrophil granulocytes and reduced control of burn wound infection

    Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Christoffersen, L., Damlund, D. S. M., Alhede, M., Bjarnsholt, Thomas, Hougen, H. P., Givskov, Michael, Jacobsen, G. K. & Høiby, Niels, 2008, In: Clinical and Experimental Immunology. 156, 1, p. 102-110 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Why chronic wounds will not heal: a novel hypothesis

    Bjarnsholt, Thomas, Kirketerp-Møller, K., Jensen, Peter Østrup, Madsen, K. G., Phipps, R. K., Krogfelt, K., Høiby, Niels & Givskov, Michael, 2008, In: Wound Repair and Regeneration. 16, 1, p. 2-10 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. 2007
  45. Published

    Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens

    Bjarnsholt, Thomas & Givskov, M. C., 29 Jul 2007, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 362, 1483, p. 1213-22 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.

    Høiby, Niels, Johansen, Helle Krogh, Ciofu, Oana, Jensen, Peter Østrup, Bjarnsholt, Thomas & Givskov, Michael, 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model

    Hultqvist, Louise Dahl, Moser, C., Jensen, Peter Østrup, Rasmussen, T. B., Christophersen, L., Kjelleberg, S., Kumar, N., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2007, In: Microbiology. 153, Pt 7, p. 2312-20 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Quorum sensing antagonism from marine organisms

    Skindersoe, M. E., Ettinger-Epstein, P., Rasmussen, T. B., Bjarnsholt, Thomas, de Nys, R. & Givskov, Michael, 2007, In: Marine Biotechnology. 10, 1, p. 56-63 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  49. Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens

    Bjarnsholt, Thomas & Givskov, M., 2007, In: Philosophical Transactions of the Royal Society of London. Biological Sciences. 362, 1483, p. 1213-22 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa

    Jensen, Peter Østrup, Bjarnsholt, Thomas, Phipps, R., Rasmussen, T. B., Calum, H., Christoffersen, L., Moser, C., Williams, P., Pressler, T., Givskov, Michael & Høiby, Niels, 2007, In: Microbiology. 153, Pt 5, p. 1329-38 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Silver against Pseudomonas aeruginosa biofilms

    Bjarnsholt, Thomas, Kirketerp-Møller, K., Kristiansen, S., Phipps, R., Nielsen, A. K., Jensen, Peter Østrup, Høiby, Niels & Givskov, Michael, 2007, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 115, 8, p. 921-8 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  52. 2006
  53. Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein

    Schreiber, K., Boes, N., Eschbach, M., Jaensch, L., Wehland, J., Bjarnsholt, Thomas, Givskov, M., Hentzer, M. & Schobert, M., 2006, In: Journal of Bacteriology. 188, 2, p. 659-68 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils

    Fexby, S., Bjarnsholt, Thomas, Jensen, Peter Østrup, Roos, V., Høiby, Niels, Givskov, Michael & Klemm, P., 2006, In: Infection and Immunity. 75, 1, p. 30-4 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  55. The role of quorum sensing in the pathogenicity of the cunning aggressor Pseudomonas aeruginosa

    Bjarnsholt, Thomas & Givskov, M., 2006, In: Analytical and Bioanalytical Chemistry. 387, 2, p. 409-14 5 p.

    Research output: Contribution to journalJournal articlepeer-review

ID: 9755066