Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

Research output: Contribution to journal › Review › Research › peer-review

Standard

Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections. / Burmølle, Mette; Thomsen, Trine Rolighed; Fazli, Mustafa; Dige, Irene; Christensen, Lise; Homøe, Preben; Tvede, Michael; Nyvad, Bente; Tolker-Nielsen, Tim; Givskov, Michael; Moser, Claus Ernst; Kirketerp-Møller, Klaus; Johansen, Helle Krogh; Høiby, Niels; Jensen, Peter Østrup; Sørensen, Søren Johannes; Bjarnsholt, Thomas.

In: FEMS Immunology and Medical Microbiology, Vol. 59, No. 3, 2010, p. 324-336.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Burmølle, M, Thomsen, TR, Fazli, M, Dige, I, Christensen, L, Homøe, P, Tvede, M, Nyvad, B, Tolker-Nielsen, T, Givskov, M, Moser, CE, Kirketerp-Møller, K, Johansen, HK, Høiby, N, Jensen, PØ, Sørensen, SJ & Bjarnsholt, T 2010, 'Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections', FEMS Immunology and Medical Microbiology, vol. 59, no. 3, pp. 324-336. https://doi.org/10.1111/j.1574-695X.2010.00714.x

APA

Burmølle, M., Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, P., Tvede, M., Nyvad, B., Tolker-Nielsen, T., Givskov, M., Moser, C. E., Kirketerp-Møller, K., Johansen, H. K., Høiby, N., Jensen, P. Ø., Sørensen, S. J., & Bjarnsholt, T. (2010). Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections. FEMS Immunology and Medical Microbiology, 59(3), 324-336. https://doi.org/10.1111/j.1574-695X.2010.00714.x

Vancouver

Burmølle M, Thomsen TR, Fazli M, Dige I, Christensen L, Homøe P et al. Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections. FEMS Immunology and Medical Microbiology. 2010;59(3):324-336. https://doi.org/10.1111/j.1574-695X.2010.00714.x

Author

Burmølle, Mette ; Thomsen, Trine Rolighed ; Fazli, Mustafa ; Dige, Irene ; Christensen, Lise ; Homøe, Preben ; Tvede, Michael ; Nyvad, Bente ; Tolker-Nielsen, Tim ; Givskov, Michael ; Moser, Claus Ernst ; Kirketerp-Møller, Klaus ; Johansen, Helle Krogh ; Høiby, Niels ; Jensen, Peter Østrup ; Sørensen, Søren Johannes ; Bjarnsholt, Thomas. / Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections. In: FEMS Immunology and Medical Microbiology. 2010 ; Vol. 59, No. 3. pp. 324-336.

Bibtex

@article{f448d350a2e811df928f000ea68e967b,
title = "Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections",
abstract = "It has become evident that aggregation or biofilm formation is an important survival mechanism for bacteria in almost any environment. In this review, we summarize recent visualizations of bacterial aggregates in several chronic infections (chronic otitis media, cystic fibrosis, infection due to permanent tissue fillers and chronic wounds) both as to distribution (such as where in the wound bed) and organization (monospecies or multispecies microcolonies). We correlate these biofilm observations to observations of commensal biofilms (dental and intestine) and biofilms in natural ecosystems (soil). The observations of the chronic biofilm infections point toward a trend of low bacterial diversity and sovereign monospecies biofilm aggregates even though the infection in which they reside are multispecies. In contrast to this, commensal and natural biofilm aggregates contain multiple species that are believed to coexist, interact and form biofilms with high bacterial and niche diversity. We discuss these differences from both the diagnostic and the scientific point of view.",
keywords = "biofilm, chronic infections, diagnostics, IN-SITU HYBRIDIZATION, VENOUS LEG ULCERS, NONTYPABLE HAEMOPHILUS-INFLUENZAE, PSEUDOMONAS-AERUGINOSA BIOFILMS, INITIAL DENTAL BIOFILM, BACTERIAL DIVERSITY, CHRONIC WOUNDS, POLYMORPHONUCLEAR LEUKOCYTES, OTITIS-MEDIA, MIDDLE-EAR",
author = "Mette Burm{\o}lle and Thomsen, {Trine Rolighed} and Mustafa Fazli and Irene Dige and Lise Christensen and Preben Hom{\o}e and Michael Tvede and Bente Nyvad and Tim Tolker-Nielsen and Michael Givskov and Moser, {Claus Ernst} and Klaus Kirketerp-M{\o}ller and Johansen, {Helle Krogh} and Niels H{\o}iby and Jensen, {Peter {\O}strup} and S{\o}rensen, {S{\o}ren Johannes} and Thomas Bjarnsholt",
year = "2010",
doi = "10.1111/j.1574-695X.2010.00714.x",
language = "English",
volume = "59",
pages = "324--336",
journal = "Pathogens and Disease",
issn = "2049-632X",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

AU - Burmølle, Mette

AU - Thomsen, Trine Rolighed

AU - Fazli, Mustafa

AU - Dige, Irene

AU - Christensen, Lise

AU - Homøe, Preben

AU - Tvede, Michael

AU - Nyvad, Bente

AU - Tolker-Nielsen, Tim

AU - Givskov, Michael

AU - Moser, Claus Ernst

AU - Kirketerp-Møller, Klaus

AU - Johansen, Helle Krogh

AU - Høiby, Niels

AU - Jensen, Peter Østrup

AU - Sørensen, Søren Johannes

AU - Bjarnsholt, Thomas

PY - 2010

Y1 - 2010

N2 - It has become evident that aggregation or biofilm formation is an important survival mechanism for bacteria in almost any environment. In this review, we summarize recent visualizations of bacterial aggregates in several chronic infections (chronic otitis media, cystic fibrosis, infection due to permanent tissue fillers and chronic wounds) both as to distribution (such as where in the wound bed) and organization (monospecies or multispecies microcolonies). We correlate these biofilm observations to observations of commensal biofilms (dental and intestine) and biofilms in natural ecosystems (soil). The observations of the chronic biofilm infections point toward a trend of low bacterial diversity and sovereign monospecies biofilm aggregates even though the infection in which they reside are multispecies. In contrast to this, commensal and natural biofilm aggregates contain multiple species that are believed to coexist, interact and form biofilms with high bacterial and niche diversity. We discuss these differences from both the diagnostic and the scientific point of view.

AB - It has become evident that aggregation or biofilm formation is an important survival mechanism for bacteria in almost any environment. In this review, we summarize recent visualizations of bacterial aggregates in several chronic infections (chronic otitis media, cystic fibrosis, infection due to permanent tissue fillers and chronic wounds) both as to distribution (such as where in the wound bed) and organization (monospecies or multispecies microcolonies). We correlate these biofilm observations to observations of commensal biofilms (dental and intestine) and biofilms in natural ecosystems (soil). The observations of the chronic biofilm infections point toward a trend of low bacterial diversity and sovereign monospecies biofilm aggregates even though the infection in which they reside are multispecies. In contrast to this, commensal and natural biofilm aggregates contain multiple species that are believed to coexist, interact and form biofilms with high bacterial and niche diversity. We discuss these differences from both the diagnostic and the scientific point of view.

KW - biofilm

KW - chronic infections

KW - diagnostics

KW - IN-SITU HYBRIDIZATION

KW - VENOUS LEG ULCERS

KW - NONTYPABLE HAEMOPHILUS-INFLUENZAE

KW - PSEUDOMONAS-AERUGINOSA BIOFILMS

KW - INITIAL DENTAL BIOFILM

KW - BACTERIAL DIVERSITY

KW - CHRONIC WOUNDS

KW - POLYMORPHONUCLEAR LEUKOCYTES

KW - OTITIS-MEDIA

KW - MIDDLE-EAR

U2 - 10.1111/j.1574-695X.2010.00714.x

DO - 10.1111/j.1574-695X.2010.00714.x

M3 - Review

C2 - 20602635

VL - 59

SP - 324

EP - 336

JO - Pathogens and Disease

JF - Pathogens and Disease

SN - 2049-632X

IS - 3

ER -

ID: 21257655