Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.
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Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing. / Høiby, Niels; Johansen, Helle Krogh; Ciofu, Oana; Jensen, Peter Østrup; Bjarnsholt, Thomas; Givskov, Michael.
In: Ugeskrift for læger, Vol. 169, No. 48, 2007, p. 4163-6.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.
AU - Høiby, Niels
AU - Johansen, Helle Krogh
AU - Ciofu, Oana
AU - Jensen, Peter Østrup
AU - Bjarnsholt, Thomas
AU - Givskov, Michael
N1 - Keywords: Anti-Bacterial Agents; Antibiotic Prophylaxis; Biofilms; Drug Resistance, Bacterial; Foreign-Body Reaction; Humans; Infection Control; Pseudomonas Infections; Pseudomonas aeruginosa; Quorum Sensing
PY - 2007
Y1 - 2007
N2 - Biofilms are structured consortia of bacteria embedded in self-produced polymer matrix. Biofilms are resistant to antibiotics, disinfectives and phagocytosis. The persistence of foreign body infections is due to biofilms. Chronic P. aeruginosa lung infection in cystic fibrosis patients is a biofilm. Bacteria in biofilms communicate by means of quorum sensing which activates genes for virulence factors. Biofilms can be prevented by antibiotic prophylaxis or early therapy or by quorum sensing inhibitors which make them susceptible to antibiotics and phagocytosis. Udgivelsesdato: 2007-Nov-26
AB - Biofilms are structured consortia of bacteria embedded in self-produced polymer matrix. Biofilms are resistant to antibiotics, disinfectives and phagocytosis. The persistence of foreign body infections is due to biofilms. Chronic P. aeruginosa lung infection in cystic fibrosis patients is a biofilm. Bacteria in biofilms communicate by means of quorum sensing which activates genes for virulence factors. Biofilms can be prevented by antibiotic prophylaxis or early therapy or by quorum sensing inhibitors which make them susceptible to antibiotics and phagocytosis. Udgivelsesdato: 2007-Nov-26
M3 - Tidsskriftartikel
C2 - 18211783
VL - 169
SP - 4163
EP - 4166
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 48
ER -
ID: 8744681