The biofilm life cycle: expanding the conceptual model of biofilm formation

Research output: Contribution to journalReviewpeer-review

Standard

The biofilm life cycle : expanding the conceptual model of biofilm formation. / Sauer, Karin; Stoodley, Paul; Goeres, Darla M.; Hall-Stoodley, Luanne; Burmølle, Mette; Stewart, Philip S.; Bjarnsholt, Thomas.

In: Nature Reviews Microbiology, Vol. 20, No. 10, 2022, p. 608-620.

Research output: Contribution to journalReviewpeer-review

Harvard

Sauer, K, Stoodley, P, Goeres, DM, Hall-Stoodley, L, Burmølle, M, Stewart, PS & Bjarnsholt, T 2022, 'The biofilm life cycle: expanding the conceptual model of biofilm formation', Nature Reviews Microbiology, vol. 20, no. 10, pp. 608-620. https://doi.org/10.1038/s41579-022-00767-0

APA

Sauer, K., Stoodley, P., Goeres, D. M., Hall-Stoodley, L., Burmølle, M., Stewart, P. S., & Bjarnsholt, T. (2022). The biofilm life cycle: expanding the conceptual model of biofilm formation. Nature Reviews Microbiology, 20(10), 608-620. https://doi.org/10.1038/s41579-022-00767-0

Vancouver

Sauer K, Stoodley P, Goeres DM, Hall-Stoodley L, Burmølle M, Stewart PS et al. The biofilm life cycle: expanding the conceptual model of biofilm formation. Nature Reviews Microbiology. 2022;20(10):608-620. https://doi.org/10.1038/s41579-022-00767-0

Author

Sauer, Karin ; Stoodley, Paul ; Goeres, Darla M. ; Hall-Stoodley, Luanne ; Burmølle, Mette ; Stewart, Philip S. ; Bjarnsholt, Thomas. / The biofilm life cycle : expanding the conceptual model of biofilm formation. In: Nature Reviews Microbiology. 2022 ; Vol. 20, No. 10. pp. 608-620.

Bibtex

@article{a46edd94a35246a48c288e1dba7410b5,
title = "The biofilm life cycle: expanding the conceptual model of biofilm formation",
abstract = "Bacterial biofilms are often defined as communities of surface-attached bacteria and are typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas aeruginosa. However, it has become evident that this is not how all biofilms develop, especially in vivo, in clinical and industrial settings, and in the environment, where biofilms often are observed as non-surface-attached aggregates. In this Review, we describe the origin of the current five-step biofilm development model and why it fails to capture many aspects of bacterial biofilm physiology. We aim to present a simplistic developmental model for biofilm formation that is flexible enough to include all the diverse scenarios and microenvironments where biofilms are formed. With this new expanded, inclusive model, we hereby introduce a common platform for developing an understanding of biofilms and anti-biofilm strategies that can be tailored to the microenvironment under investigation.",
author = "Karin Sauer and Paul Stoodley and Goeres, {Darla M.} and Luanne Hall-Stoodley and Mette Burm{\o}lle and Stewart, {Philip S.} and Thomas Bjarnsholt",
note = "Publisher Copyright: {\textcopyright} 2022, Springer Nature Limited.",
year = "2022",
doi = "10.1038/s41579-022-00767-0",
language = "English",
volume = "20",
pages = "608--620",
journal = "Nature Reviews. Microbiology",
issn = "1740-1526",
publisher = "nature publishing group",
number = "10",

}

RIS

TY - JOUR

T1 - The biofilm life cycle

T2 - expanding the conceptual model of biofilm formation

AU - Sauer, Karin

AU - Stoodley, Paul

AU - Goeres, Darla M.

AU - Hall-Stoodley, Luanne

AU - Burmølle, Mette

AU - Stewart, Philip S.

AU - Bjarnsholt, Thomas

N1 - Publisher Copyright: © 2022, Springer Nature Limited.

PY - 2022

Y1 - 2022

N2 - Bacterial biofilms are often defined as communities of surface-attached bacteria and are typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas aeruginosa. However, it has become evident that this is not how all biofilms develop, especially in vivo, in clinical and industrial settings, and in the environment, where biofilms often are observed as non-surface-attached aggregates. In this Review, we describe the origin of the current five-step biofilm development model and why it fails to capture many aspects of bacterial biofilm physiology. We aim to present a simplistic developmental model for biofilm formation that is flexible enough to include all the diverse scenarios and microenvironments where biofilms are formed. With this new expanded, inclusive model, we hereby introduce a common platform for developing an understanding of biofilms and anti-biofilm strategies that can be tailored to the microenvironment under investigation.

AB - Bacterial biofilms are often defined as communities of surface-attached bacteria and are typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas aeruginosa. However, it has become evident that this is not how all biofilms develop, especially in vivo, in clinical and industrial settings, and in the environment, where biofilms often are observed as non-surface-attached aggregates. In this Review, we describe the origin of the current five-step biofilm development model and why it fails to capture many aspects of bacterial biofilm physiology. We aim to present a simplistic developmental model for biofilm formation that is flexible enough to include all the diverse scenarios and microenvironments where biofilms are formed. With this new expanded, inclusive model, we hereby introduce a common platform for developing an understanding of biofilms and anti-biofilm strategies that can be tailored to the microenvironment under investigation.

U2 - 10.1038/s41579-022-00767-0

DO - 10.1038/s41579-022-00767-0

M3 - Review

C2 - 35922483

AN - SCOPUS:85135352110

VL - 20

SP - 608

EP - 620

JO - Nature Reviews. Microbiology

JF - Nature Reviews. Microbiology

SN - 1740-1526

IS - 10

ER -

ID: 316747977