Niels Høiby

Niels Høiby

Professor, No job title

Member of:


    1. Published

      Extensive endoscopic image-guided sinus surgery decreases BPI-ANCA in patients with cystic fibrosis

      Aanæs, Kasper, Rasmussen, N., Pressler, T., Segelmark, M., Johansen, Helle Krogh, Lindberg, U., Høiby, Niels, Carlsson, M., Wieslander, J. & Buchwald, C., 2012, In: Scandinavian Journal of Immunology. 76, 6, p. 573-9 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    2. Published

      Clinical effects of sinus surgery and adjuvant therapy in cystic fibrosis patients - can chronic lung infections be postponed?

      Aanæs, Kasper, Johansen, Helle Krogh, Skov, M., Buchvald, F. F., Hjuler, Thomas, Pressler, T., Høiby, Niels, Nielsen, Kim G. & von Buchwald, Christian, 2013, In: Rhinology. 51, 3, p. 222-230 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization

      Aanæs, Kasper, Johansen, Helle Krogh, Poulsen, Steen Seier, Pressler, T., Buchwald, C. & Høiby, Niels, 2012, In: Journal of Cystic Fibrosis. 12, 1, p. 81-87 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Autologous fibrin sealant co-delivered with antibiotics is a robust method for topical antibiotic treatment after sinus surgery

      Aanæs, Kasper, Nielsen, Kim G., Arndal, E., von Buchwald, Christian, Pressler, T. & Høiby, Niels, 1 Feb 2021, In: Acta Oto-Laryngologica. 141, 2, p. 181-186 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?

      Aanæs, Kasper, Eickhardt, S., Johansen, Helle Krogh, von Buchwald, Christian, Skov, M., Høiby, Niels & Bjarnsholt, Thomas, 2014, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. p. 1-7 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis

      Aanæs, Kasper, Rickelt, L. F., Johansen, Helle Krogh, von Buchwald, Christian, Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2011, In: Journal of Cystic Fibrosis. 10, 2, p. 114-120 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      The evolutionary trajectories of P. aeruginosa in biofilm and planktonic growth modes exposed to ciprofloxacin: beyond selection of antibiotic resistance

      Ahmed, M. N., Abdelsamad, A., Wassermann, T., Porse, A., Becker, J., Sommer, M. O. A., Høiby, Niels & Ciofu, Oana, 2020, In: npj Biofilms and Microbiomes. 6, 1, 10 p., 28.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Lack of the Major Multifunctional Catalase KatA in Pseudomonas aeruginosa Accelerates Evolution of Antibiotic Resistance in Ciprofloxacin-Treated Biofilms

      Ahmed, M. N., Porse, A., Abdelsamad, A., Sommer, M., Høiby, Niels & Ciofu, Oana, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 10, 12 p., e00766-19.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Evolution of Antibiotic Resistance in Biofilm and Planktonic Pseudomonas aeruginosa Populations Exposed to Subinhibitory Levels of Ciprofloxacin

      Ahmed, M. N. A., Porse, A., Sommer, M., Høiby, Niels & Ciofu, Oana, 1 Aug 2018, In: Antimicrobial Agents and Chemotherapy. 62, 8, 12 p., e00320-18.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Sinus surgery postpones chronic gram-negative lung infection: Cohort study of 106 patients with cystic fibrosis

      Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G., Taylor-Robinson, D., Waldmann, E., Johansen, Helle Krogh & von Buchwald, Christian, 2016, In: Rhinology. 54, 3, p. 206-213 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia

      Alanin, M. C., Nielsen, K. G., von Buchwald, Christian, Skov, M., Aanæs, Kasper, Høiby, Niels & Johansen, Helle Krogh, Dec 2015, In: Clinical Microbiology and Infection. 21, 12, p. 1093.e1–1093.e7 7 p., 1093.e.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia

      Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, Kim G., Johansen, Helle Krogh & von Buchwald, Christian, Mar 2017, In: International Forum of Allergy Rhinology. 7, 3, p. 240-247

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia

      Alanin, M. C., Johansen, Helle Krogh, Aanaes, K., Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G. & von Buchwald, Christian, Jan 2015, In: Acta Oto-Laryngologica. 135, 1, p. 58-63 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study

      Alanin, M. C., Pressler, T., Aanæs, Kasper, Ekstrøm, Claus Thorn, Skov, M., Johansen, Helle Krogh, Nielsen, Kim G., von Buchwald, Christian & Høiby, Niels, 2018, In: Health Services Research. 1, 8, 5 p., e52.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm

      Alhede, M., Kragh, K. N., Qvortrup, Klaus, Allesen-Holm, M., van Gennip, M., Hultqvist, Louise Dahl, Jensen, Peter Østrup, Nielsen, A. K., Parsek, M., Wozniak, D., Molin, S., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2011, In: P L o S One. 6, 11, p. e27943

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Bacterial biofilm formation and treatment in soft tissue fillers

      Alhede, M., Er, O., Eickhardt, S., Kragh, K., Alhede, M., Hultqvist, Louise Dahl, Poulsen, Steen Seier, Givskov, Michael, Christensen, L. H., Høiby, Niels, Tvede, M. & Bjarnsholt, Thomas, 30 Jan 2014, In: Pathogens and Disease. 70, p. 339-346 8 p.

      Research output: Contribution to journalJournal articleResearch

    17. Published

      Phenotype of non-attached Pseudomonas aeruginosa microclonies resembles attached biofilm, including reversible antibiotic tolerance

      Alhede, M., Qvortrup, K., Allesen-Holm, M., van Gennip, M., Christensen, L., Jensen, Peter Østrup, Nielsen, A., Tolker-Nielsen, T., Høiby, Niels, Givskov, M. C. & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    18. Published

      Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes

      Alhede, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Phipps, R. K., Moser, Claus Ernst, Christophersen, L., Hultqvist, Louise Dahl, van Gennip, M., Parsek, M., Høiby, Niels, Rasmussen, T. B. & Givskov, Michael, 2009, In: Microbiology. 155, 11, p. 3500-3508 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Combination of microscopic techniques reveals a comprehensive visual impression of biofilm structure and composition

      Alhede, M., Qvortrup, Klaus, Liebrechts, R., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 335-342 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Colistin Enhances Rifampicin's Antimicrobial Action in Colistin-Resistant Pseudomonas aeruginosa Biofilms

      Armengol, E., Kragh, K. N., Tolker-Nielsen, Tim, Sierra, J. M., Higazy, Doaa Mohamed Mohamed E, Ciofu, Oana, Viñas, M. & Høiby, Niels, 2023, In: Antimicrobial Agents and Chemotherapy. 67, 4, e0164122.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs

      Arndal, E., Johansen, Helle Krogh, Haagensen, J. A. J., Bartell, J. A., Marvig, R. L., Alanin, M., Aanæs, Kasper, Høiby, Niels, Nielsen, Kim G., Backer, Vibeke & von Buchwald, Christian, 2020, In: The European Respiratory Journal. 55, 1, 4 p., 1901472.

      Research output: Contribution to journalLetterResearchpeer-review

    22. Published

      Rapid development in vitro and in vivo of resistance to ceftazidime in biofilm-growing Pseudomonas aeruginosa due to chromosomal beta-lactamase

      Bagge, N., Ciofu, Oana, Skovgaard, Lene Theil & Høiby, Niels, Sep 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 9, p. 589-600 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD.

      Bagge, N., Ciofu, Oana, Hentzer, M., Campbell, J. I. A., Givskov, Michael & Høiby, Niels, 2002, In: Antimicrobial Agents and Chemotherapy. 46, 11, p. 3406-11 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Dynamics and spatial distribution of beta-lactamase expression in Pseudomonas aeruginosa biofilms.

      Bagge, N., Hentzer, M., Andersen, Jens Bo, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1168-74 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production.

      Bagge, N., Schuster, M., Hentzer, M., Ciofu, Oana, Givskov, Michael, Greenberg, E. P. & Høiby, Niels, 2004, In: Antimicrobial Agents and Chemotherapy. 48, 4, p. 1175-87 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Restriction fragment length polymorphism of rRNA genes for molecular typing of members of the family Legionellaceae.

      Bangsborg, Jette Marie, Gerner-Smidt, P., Colding, H., Fiehn, Nils-Erik, Bruun, B. & Høiby, Niels, 1995, In: Journal of Clinical Microbiology. 33, 2, p. 402-6 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      The Legionella micdadei flagellin: expression in Escherichia coli K 12 and DNA sequence of the gene

      Bangsborg, Jette Marie, Hindersson, P., Shand, G. & Høiby, Niels, 1995, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 103, 12, p. 869-77 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Cloning and expression of the Legionella micdadei "common antigen" in Escherichia coli

      Bangsborg, Jette Marie, Collins, M. T., Høiby, Niels & Hindersson, P., 1989, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 97, 1, p. 14-22 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Antibody response to major cross-reactive Legionella antigens during infection

      Bangsborg, Jette Marie, Shand, G. & Høiby, Niels, 1993, Legionella: Current status and emerging perspectives. USA: ASM, p. 26-29

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    30. Published

      Cross-reactive Legionella antigens and the antibody response during infection

      Bangsborg, Jette Marie, Shand, G., Pearlman, E. & Høiby, Niels, 1991, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 99, 9, p. 854-65 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      The E. coli immunosorbent as used in serodiagnosis of Legionella infections studied by crossed immunoelectrophoresis

      Bangsborg, Jette Marie, Friis-Møller, A., Rechnitzer, C., Høiby, Niels & Lind, K., 1988, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 96, 2, p. 177-84 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      The Leginella micdadei flagellin: Expression in Escherichia coli K12 and DNA sequence of the gene

      Bangsborg, Jette Marie, Hindersson, P., Shand, G. & Høiby, Niels, 1995, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. p. 869-877

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Comparison of ribotyping and genome fingerprinting of Pseudomonas aeruginosa isolates from cystic fibrosis patients.

      Bennekov, T., Colding, H., Ojeniyi, B., Bentzon, M. W. & Høiby, Niels, 1996, In: Journal of Clinical Microbiology. 34, 1, p. 202-4 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Urinary tract infections with spinal cord lesions: Treatment and prevention

      Biering-Sørensen, F., Bagi, P. & Høiby, Niels, 2001, In: Drugs. 61, p. 1275-1287

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Summary and Perspectives

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, 2010, Biofilm Infections. Bjarnsholt, T., Moser, C. E., Jensen, P. Ø. & Høiby, N. (eds.). 1st ed. New York. NY. US: Springer Science+Business Media, p. 291-293 3 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    36. Published

      Summary and perspectives

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, 2011, Biofilm Infections. Springer New York, p. 291-294 4 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    37. Published

      Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections

      Bjarnsholt, Thomas, Jensen, P. Ø., Rasmussen, T. B., Christophersen, L., Calum, H., Hentzer, M., Hougen, H. P., Rygaard, J., Moser, C., Eberl, L., Høiby, Niels & Givskov, M. C., 1 Dec 2005, In: Microbiology. 151, Pt 12, p. 3873-80 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Burmølle, Mette, Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, Claus Ernst, Molin, S., Høiby, Niels & Givskov, Michael, Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Process for the manufacture of ajoene derivatives

      Bjarnsholt, Thomas, Høiby, Niels, Jensen, Peter Østrup, Phipps, R., Shanmugham, Meenakshi, S., Alhede, M., Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Tanner, D., Larsen, Thomas, O. & Givskov, Michael, 14 Jun 2012, IPC No. C07C 323/ 65 A I, Patent No. WO2012076016, Priority date 8 Dec 2010, Priority No. EP20100194154

      Research output: Patent

    40. Published

      Silver against Pseudomonas aeruginosa biofilms

      Bjarnsholt, Thomas, Kirketerp-Møller, K., Kristiansen, S., Phipps, R., Nielsen, A. K., Jensen, Peter Østrup, Høiby, Niels & Givskov, Michael, 2007, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 115, 8, p. 921-8 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Applying insights from biofilm biology to drug development - can a new approach be developed?

      Bjarnsholt, Thomas, Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Oct 2013, In: Nature Reviews. Drug Discovery. 12, 10, p. 791-808 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      The in vivo biofilm

      Bjarnsholt, Thomas, Alhede, M., Alhede, M., Eickhardt-Sørensen, S. R., Moser, Claus Ernst, Kühl, Michael, Jensen, Peter Østrup & Høiby, Niels, 2013, In: Trends in Microbiology. 21, 9, p. 466-474 9 p.

      Research output: Contribution to journalReviewResearchpeer-review

    43. Published

      Biofilm infections

      Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup & Høiby, Niels, 2011, Springer New York. 314 p.

      Research output: Book/ReportBookResearchpeer-review

    44. Published

      Methods to classify bacterial pathogens in cystic fibrosis

      Bjarnsholt, Thomas, Nielsen, X. C., Johansen, U., Nørgaard, L. & Høiby, Niels, 2011, In: Methods in Molecular Biology. 742, p. 143-71 29 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Fiandaca, M. J., Pedersen, J., Hansen, C. R., Andersen, C. B., Pressler, T., Givskov, Michael & Høiby, Niels, 1 Jun 2009, In: Pediatric Pulmonology. 44, 6, p. 547-58 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Antibiofilm Properties of Acetic Acid

      Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

      Bjarnsholt, Thomas, Jensen, P. Ø., Burmølle, M., Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, C., Molin, S., Høiby, Niels & Givskov, M. C., 1 Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Understanding biofilms - Are we there yet?

      Bjarnsholt, Thomas, Høiby, Niels, Donelli, G., Imbert, C. & Försberg, A., Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 125-126 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudo-monas aeruginosa infections.

      Bjarnsholt, Thomas, Jensen, P. Ø., Rasmussen, T. B., Christoffersen, L., Calum, Henrik Pierre, Hentzer, M., Hougen, H. P., Rygaard, J., Moser, Claus Ernst, Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: F E M S Microbiology. 151, p. 3873-3880 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control

      Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 2010, In: Expert Reviews in Molecular Medicine. 12, p. e11 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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