Niels Høiby

Niels Høiby

Professor, No job title

Member of:


    1. 2018
    2. Published

      A systematic review of studies on the faecal microbiota in anorexia nervosa: future research may need to include microbiota from the small intestine

      Schwensen, H. F., Kan, C., Treasure, J., Høiby, Niels & Sjögren, M., 2018, In: Eating and Weight Disorders. 23, 4, p. 399-418

      Research output: Contribution to journalReviewResearchpeer-review

    3. Published

      Adaptation of Pseudomonas aeruginosa to the chronic phenotype by mutations in the algTmucABD operon in isolates from Brazilian cystic fibrosis patients

      Caçador, N. C., Paulino da Costa Capizzani, C., Monteiro Marin Torres, L. A. G., Galetti, R., Ciofu, Oana, Lúcia da Costa Darini, A. & Høiby, Niels, 2018, In: PLoS ONE. 13, 11, 11 p., e0208013.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study

      Alanin, M. C., Pressler, T., Aanæs, Kasper, Ekstrøm, Claus Thorn, Skov, M., Johansen, Helle Krogh, Nielsen, Kim G., von Buchwald, Christian & Høiby, Niels, 2018, In: Health Services Research. 1, 8, 5 p., e52.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      IgG avidity to Pseudomonas aeruginosa over the course of chronic lung biofilm infection in cystic fibrosis

      Mauch, R. M., Nørregaard, L. L., Ciofu, Oana, Levy, C. E. & Høiby, Niels, 2018, In: Journal of Cystic Fibrosis. 17, 3, p. 356-359

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis

      Mauch, R. M., Jensen, Peter Østrup, Moser, Claus Ernst, Levy, C. E. & Høiby, Niels, 2018, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17, 2, p. 143-152

      Research output: Contribution to journalReviewResearchpeer-review

    7. Published

      Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms

      Gade, P. A. V., Olsen, T. B., Jensen, Peter Østrup, Kolpen, Mette, Høiby, Niels, Henneberg, K. Å. & Sams, T., 2018, In: PLoS ONE. 13, 6, 16 p., e0198909.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Next generation microbiology and cystic fibrosis diagnostics: are we there yet?

      Moser, Claus Ernst, Thomsen, T. R. & Høiby, Niels, 2018, In: Current Opinion in Pulmonary Medicine. 24, 6, p. 599-605

      Research output: Contribution to journalReviewResearchpeer-review

    9. Published

      The importance of early diagnosis of Mycobacterium abscessus complex in patients with cystic fibrosis

      Ravnholt, C., Kolpen, M., Skov, M., Moser, C., Katzenstein, T. L., Pressler, T., Høiby, Niels & Qvist, T., 2018, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 126, 12, p. 885-891 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. 2017
    11. Published

      Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin

      Kolpen, Mette, Lerche, C. J., Kragh, K. N., Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines—implications for delayed wound closure?

      Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Oct 2017, In: Pathogens and Disease. 75, 7, 10 p., ftx068.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM

      Kolpen, M., Ravnholt, C., Qvist, T., Kragh, K., Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    14. Published

      Experimental Pseudomonas aeruginosa mediated rhino sinusitis in mink

      Kirkeby, Svend, Hammer, Anne Sofie Vedsted, Høiby, Niels & Salomonsen, C. M., May 2017, In: International Journal of Pediatric Otorhinolaryngology. 96, p. 156-163 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      A short history of microbial biofilms and biofilm infections

      Høiby, Niels, Apr 2017, In: APMIS. 125, 4, p. 272-275 4 p.

      Research output: Contribution to journalReviewResearchpeer-review

    16. Published

      Biofilms and host response - helpful or harmful

      Moser, Claus Ernst, Pedersen, H. T., Lerche, C. J., Kolpen, Mette, Line, L., Thomsen, K., Høiby, Niels & Jensen, Peter Østrup, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 320-338 19 p.

      Research output: Contribution to journalReviewResearchpeer-review

    17. Published

      Chronic urinary tract infections in patients with spinal cord lesions – biofilm infection with need for long-term antibiotic treatment

      Tofte, N., Nielsen, A. C. Y., Trøstrup, H., Andersen, C. B., Von Linstow, M., Hansen, B., Biering-Sørensen, Fin, Høiby, Niels & Moser, Claus Ernst, Apr 2017, In: APMIS. 125, 4, p. 385-391 7 p.

      Research output: Contribution to journalReviewResearchpeer-review

    18. Published

      Diagnosis of biofilm infections in cystic fibrosis patients

      Høiby, Niels, Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup, Kolpen, Mette, Qvist, T., Aanæs, Kasper, Pressler, T., Skov, M. & Ciofu, Oana, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 339-343 5 p.

      Research output: Contribution to journalReviewResearchpeer-review

    19. Published

      Individual pharmacokinetic variation leads to underdosing of ciprofloxacin in some cystic fibrosis patients

      Schultz, A. N. Ø., Høiby, Niels, Nielsen, X. C., Pressler, T., Dalhoff, Kim, Duno, M., Buchard, Anders, Johansen, H. K., Wang, H. & Dalbøge, C. S., Mar 2017, In: Pediatric Pulmonology. 52, 3, p. 319-323 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Phenotypic shift in Pseudomonas aeruginosa populations from cystic fibrosis lungs after 2-week antipseudomonal treatment

      Fernandez-Barat, L., Ciofu, Oana, Kragh, K. N., Pressler, T., Johansen, U., Motos, A., Torres, A. & Høiby, Niels, Mar 2017, In: Journal of Cystic Fibrosis. 16, 2, p. 222-229

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia

      Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, Kim G., Johansen, Helle Krogh & von Buchwald, Christian, Mar 2017, In: International Forum of Allergy Rhinology. 7, 3, p. 240-247

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Evaluation of a bovine antibody test for diagnosing Mycobacterium avium complex in patients with cystic fibrosis

      Qvist, T., Pressler, T., Katzenstein, T. L., Høiby, Niels & Collins, M. T., Jan 2017, In: Pediatric Pulmonology. 52, 1, p. 34-40 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Hyperbaric oxygen treatment augments tobramycin efficacy in experimental staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Kolpen, Mette, Nielsen, P. R., Trøstrup, H., Thomsen, K., Hyldegaard, Ole, Bundgård, Henning, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Antimicrobial Agents. 50, 3, p. 406-412

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds

      Trøstrup, H., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Molecular Sciences. 18, 7, 13 p., 1359.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Secretory IgA response against Pseudomonas aeruginosa in the upper airways and the link with chronic lung infection in cystic fibrosis

      Mauch, R. M., Rossi, C. L., Aiello, T. B., Ribeiro, J. D., Ribeiro, A. F., Høiby, Niels & Levy, C. E., 2017, In: Pathogens and Disease. 75, 6, 4 p., ftx069.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Sinus bacteriology in patients with cystic fibrosis or primary ciliary dyskinesia: A systematic review

      Møller, M. E., Alanin, M. C., Grønhøj, C., Aanæs, Kasper, Høiby, Niels & von Buchwald, Christian, 2017, In: American Journal of Rhinology and Allergy. 31, 5, p. 293-298 6 p.

      Research output: Contribution to journalReviewResearchpeer-review

    27. 2016
    28. Published

      The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms

      Nilsson, Carl Martin Peter, Rybtke, Morten Levin, Givskov, Michael, Høiby, Niels, Twetman, Svante & Tolker-Nielsen, Tim, Sep 2016, In: International Journal of Antimicrobial Agents. 48, 3, p. 298–304

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      S100A8/A9 is an important host defence mediator in neuropathic foot ulcers in patients with type 2 diabetes mellitus

      Trøstrup, H., Holstein, P., Christophersen, L., Jørgensen, B., Karlsmark, Tonny, Høiby, Niels, Moser, Claus Ernst & Ågren, Magnus, 1 Jul 2016, In: Archives of Dermatological Research. 308, 5, p. 347-355 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils

      Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice

      Damlund, D. S. M., Christophersen, L., Jensen, Peter Østrup, Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2016, In: APMIS - Journal of Pathology, Microbiology and Immunology. 124, 6, p. 500-507 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      The phenotypic evolution of pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin

      Wassermann, T., Jørgensen, K. M., Ivanyshyn, K., Bjarnsholt, Thomas, Hossein Khademi, S. M., Jelsbak, L., Høiby, Niels & Ciofu, Oana, 1 May 2016, In: Microbiology. 162, 5, p. 865-875 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Diffusion retardation by binding of tobramycin in an alginate biofilm model

      Cao, B., Christophersen, L., Kolpen, Mette, Jensen, Peter Østrup, Sneppen, Kim, Høiby, Niels, Moser, Claus Ernst & Sams, T., 21 Apr 2016, In: P L o S One. 11, 4, 11 p., e0153616.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      New technology markedly improves hand-hygiene performance among healthcare workers after restroom visits

      Møller-Sørensen, H., Korshin, A., Mogensen, T. & Høiby, Niels, Apr 2016, In: Journal of Hospital Infection. 92, 4, p. 337-339 3 p.

      Research output: Contribution to journalLetterResearchpeer-review

    35. Published

      Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

      Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Animal models of chronic wound care: the application of biofilms in clinical research

      Trøstrup, H., Thomsen, K., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2016, In: Chronic Wound Care Management and Research. 3, p. 123-132 10 p.

      Research output: Contribution to journalReviewResearchpeer-review

    38. Published

      Bacterial evolution in PCD and CF patients follows the same mutational steps

      Sommer, L. M., Alanin, M. C., Marvig, R. L., Nielsen, Kim G., Høiby, Niels, von Buchwald, Christian, Molin, S. & Johansen, Helle Krogh, 2016, In: Scientific Reports. 6, 8 p., 28732.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Forøget renal udskillelse af antibiotika kan resultere i underdosering ved sepsis

      Moser, Claus Ernst, Hartvig, T., Schierbeck, J. & Høiby, Niels, 2016, In: Ugeskrift for Laeger. 178, p. 2-6 5 p., V05150426.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Genome sequence of Pseudomonas aeruginosa strain DK1-NH57388A, a stable mucoid cystic fibrosis isolate

      Norman, A., Ciofu, Oana, Amador, C. I., Høiby, Niels & Jelsbak, L., 2016, In: Genome Announcements. 4, 1, e00008-16.

      Research output: Contribution to journalJournal articleResearch

    41. Published

      Kai Adolf Jensen, professor i almindelig patologi

      Høiby, Niels, 2016, In: Bibliotek for Laeger. 208, 4, p. 344-361

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      OligoG CF-5/20 disruption of mucoid Pseudomonas aeruginosa biofilm in a murine lung infection model

      Wang, H., Song, Z., Ciofu, Oana, Onsøyen, E., Rye, P. D. & Høiby, Niels, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 5, p. 2620-2626 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment

      Kolpen, Mette, Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.

      Research output: Contribution to journalLetterResearchpeer-review

    44. Published

      Sinus surgery postpones chronic gram-negative lung infection: Cohort study of 106 patients with cystic fibrosis

      Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G., Taylor-Robinson, D., Waldmann, E., Johansen, Helle Krogh & von Buchwald, Christian, 2016, In: Rhinology. 54, 3, p. 206-213 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      The phagocytic fitness of leucopatches may impact the healing of chronic wounds

      Thomsen, K., Trøstrup, H., Christophersen, L., Lundquist, R., Høiby, Niels & Moser, Claus Ernst, 2016, In: Clinical and Experimental Immunology. 184, 3, p. 368-77 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. 2015
    47. Published

      Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis

      Lerche, C. J., Christophersen, L. J., Trøstrup, H., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Bundgaard, H., Høiby, Niels & Moser, C., 1 Dec 2015, In: European Journal of Clinical Microbiology & Infectious Diseases. 34, 12, p. 2349-2357 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia

      Alanin, M. C., Nielsen, K. G., von Buchwald, Christian, Skov, M., Aanæs, Kasper, Høiby, Niels & Johansen, Helle Krogh, Dec 2015, In: Clinical Microbiology and Infection. 21, 12, p. 1093.e1–1093.e7 7 p., 1093.e.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Chronic pulmonary disease with Mycobacterium abscessus complex is a biofilm infection

      Qvist, T., Eickhardt-Dalbøge, S. R., Kragh, K. N., Andersen, C. B., Iversen, M., Høiby, Niels & Bjarnsholt, Thomas, Dec 2015, In: European Respiratory Journal. 46, 6, p. 1823-1826 4 p.

      Research output: Contribution to journalComment/debateResearchpeer-review

    50. Published

      The LapG protein plays a role in Pseudomonas aeruginosa biofilm formation by controlling the presence of the CdrA adhesin on the cell surface

      Rybtke, Morten Levin, Berthelsen, J., Yang, L., Høiby, Niels, Givskov, Michael & Tolker-Nielsen, Tim, Dec 2015, In: MicrobiologyOpen. 4, 6, p. 917-930 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      RE-SENSITIZATION OF ANOXIC PSEUDOMONAS AERUGINOSA BIOFILMS WITH RE-OXYGENATION USING HYPERBARIC OXYGEN TREATMENT

      Kolpen, Mette, Mousavi, N., Sams, T., Kragh, K. N., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, P. O., Oct 2015, In: Pediatric Pulmonology. 50, S41, p. 312-312 1 p., 322.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    52. Published

      Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

      Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection

      Jorgensen, K. M., Wassermann, T., Johansen, Helle Krogh, Christiansen, L. E., Molin, S., Høiby, Niels & Ciofu, Oana, Jul 2015, In: Microbiology. 161, 7, p. 1447-1462 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Published

      Antibiofilm Properties of Acetic Acid

      Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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