Peter Østrup Jensen

Peter Østrup Jensen

Associate Professor


  1. 2023
  2. Published

    3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism

    Adams, Yvonne, Clausen, Anne Skovsbo, Jensen, Peter Østrup, Lager, M., Wilhelmsson, P., Henningson, A. J., Lindgren, P. E., Faurholt-Jepsen, D., Mens, H., Kraiczy, P., Kragh, Kasper Nørskov, Bjarnsholt, Thomas, Kjær, Andreas, Lebech, Anne-Mette & Jensen, Anja Ramstedt, 2023, In: iScience. 26, 1, 105838.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published
  4. 2022
  5. Published

    A novel Borrelia-specific real-time PCR assay is not suitable for diagnosing Lyme neuroborreliosis

    Pedersen, Regitze Renee, Kragh, Kasper Nørskov, Fritz, Blaine Gabriel, Ørbæk, M., Jensen, Peter Østrup, Lebech, Anne-Mette & Bjarnsholt, Thomas, 2022, In: Ticks and Tick-borne Diseases. 13, 5, 101971.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Adaptive Immune Response to Mycobacterium abscessus Complex (MABSC) in Cystic Fibrosis and the Implications of Cross-Reactivity

    Mauch, R. M., Jensen, Peter Østrup, Qvist, T., Kolpen, M., Moser, Claus Ernst, Pressler, T., Nolasco da Silva, M. T., Høiby, Niels & Copenhagen Study Group on Mycobacterial Infections in Cystic Fibrosis, C. S. G. O. M. I. I. C. F., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 858398.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

    Thomsen, K., Kobayashi, O., Kishi, K., Shirai, R., Jensen, Peter Østrup, Heydorn, A., Hentzer, M., Calum, Henrik Pierre, Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2022, In: APMIS. 130, 7, p. 458-476

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Bacterial biofilms predominate in both acute and chronic human lung infections

    Kolpen, M., Kragh, Kasper Nørskov, Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, Pernille, Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: Thorax. 77, p. 1015–1022

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Endotracheal lactate reflects lower respiratory tract infections and inflammation in intubated patients

    Kolpen, M., Dalby Sørensen, C., Faurholt-Jepsen, D., Hertz, Frederik Boëtius, Jensen, Peter Østrup & Bestle, Morten Heiberg, 2022, In: APMIS. 130, 8, p. 507-514

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Immune Response to Biofilm Growing Pulmonary Pseudomonas aeruginosa Infection

    Thomsen, K., Høiby, Niels, Jensen, Peter Østrup, Ciofu, Oana & Moser, Claus Ernst, 2022, In: Biomedicines. 10, 9, 2064.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Increased sputum lactate during oral glucose tolerance test in cystic fibrosis

    Jensen, Peter Østrup, Nielsen, B. U., Kolpen, Mette, Pressler, T., Faurholt-Jepsen, D. & Mathiesen, I. H. M., 2022, In: APMIS. 130, 8, p. 535-539

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis

    Lerche, C. J., Schwartz, Franziska Angelika, Pries-Heje, M. M., Fosbøl, E. L., Iversen, Kasper, Jensen, Peter Østrup, Høiby, Niels, Hyldegaard, Ole, Bundgård, Henning & Moser, Claus Ernst, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 805964.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Prevalence of biofilms in acute infections challenges a longstanding paradigm

    Kolpen, M., Jensen, Peter Østrup, Faurholt-Jepsen, D. & Bjarnsholt, Thomas, 2022, In: Biofilm. 4, 100080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The importance of understanding the infectious microenvironment

    Bjarnsholt, Thomas, Whiteley, M., Rumbaugh, K. P., Stewart, P. S., Jensen, Peter Østrup & Frimodt-Møller, N., 2022, In: The Lancet Infectious Diseases. 22, 3, p. e88-e92

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment

    Lichtenberg, Mads, Jakobsen, Tim Holm, Kühl, Michael, Kolpen, Mette, Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: FEMS Microbiology Reviews. 46, 5, 13 p., fuac018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Tolerance and resistance of microbial biofilms

    Ciofu, Oana, Moser, Claus Ernst, Jensen, Peter Østrup & Høiby, Niels, 2022, In: Nature Reviews Microbiology. 20, p. pages621–635

    Research output: Contribution to journalReviewResearchpeer-review

  17. 2021
  18. Published

    Delayed neutrophil recruitment allows nascent Staphylococcus aureus biofilm formation and immune evasion

    Pettygrove, B. A., Kratofil, R. M., Alhede, M., Jensen, Peter Østrup, Newton, M., Qvortrup, Klaus, Pallister, K. B., Bjarnsholt, Thomas, Kubes, P., Voyich, J. M. & Stewart, P. S., Aug 2021, In: Biomaterials. 275, 13 p., 120775.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Catalase protects biofilm of Staphylococcus aureus against daptomycin activity

    El Haj, C., Lichtenberg, Mads, Nielsen, K. L., Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: Antibiotics. 10, 5, 511.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Distinct contribution of hyperbaric oxygen therapy to human neutrophil function and antibiotic efficacy against Staphylococcus aureus

    Schwartz, Franziska Angelika, Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Laulund, A. S., Woetmann, Anders , Høiby, Niels & Moser, Claus Ernst, 2021, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 129, 9, p. 566-573

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Hyperbaric oxygen treatment impacts oxidative stress markers in patients with necrotizing soft-tissue infection

    Hedetoft, M., Jensen, Peter Østrup, Moser, Claus Ernst, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Investigative Medicine. 69, 7, p. 1330-1338

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Immune Responses to Pseudomonas aeruginosa Biofilm Infections

    Moser, Claus Ernst, Jensen, Peter Østrup, Thomsen, K., Kolpen, M., Rybtke, Morten Levin, Lauland, A. S., Trøstrup, H. & Tolker-Nielsen, Tim, 2021, In: Frontiers in Immunology. 12, 625597.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Misleading mental models: Ceci n’est pas un biofilm

    Jensen, Peter Østrup & Rumbaugh, K., 2021, In: APMIS. 129, 10, p. 577-578 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  24. Published

    Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa

    Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Soluble ICAM-1 is modulated by hyperbaric oxygen treatment and correlates with disease severity and mortality in patients with necrotizing soft-tissue infection

    Hedetoft, M., Moser, Claus Ernst, Jensen, Peter Østrup, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Applied Physiology. 130, 3, p. 729-736 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published
  27. 2020
  28. Published

    Lactobacillus rhamnosus strains of oral and vaginal origin show strong antifungal activity in vitro

    Jørgensen, Mette Rose, Rikvold, P. T., Lichtenberg, Mads, Jensen, Peter Østrup, Kragelund, Camilla & Twetman, Svante, 2020, In: Journal of Oral Microbiology. 12, 1, 8 p., 1832832.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Staphylococcus aureus augments release of matrix metalloproteinase-8 from human polymorphonuclear leukocytes

    Kirketerp-Møller, K., Bjarnsholt, Thomas, Jensen, Peter Østrup & Ågren, Magnus, 2020, In: Acta Dermato-Venereologica. 100, 15, p. 1-2 2 p., adv00232.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published
  31. Published

    Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes

    Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, Lene & Bjarnsholt, Thomas, 2020, In: Medical Microbiology and Immunology. 209, p. 669–680

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

    Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, Kasper Nørskov, Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology

    Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Human immune cell mobilization during exercise: effect of IL-6 receptor blockade

    Bay, M. L., Heywood, S., Wedell-Neergaard, A. S., Schauer, T., Lehrskov, L. L., Christensen, R. H., Legård, G. E., Jensen, Peter Østrup, Krogh-Madsen, Rikke & Ellingsgaard, H., 2020, In: Experimental Physiology. 105, 12, p. 2086-2098 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Neutrophil count in sputum is associated with increased sputum glucose and sputum L-lactate in cystic fibrosis

    Nielsen, B. U., Kolpen, M., Jensen, Peter Østrup, Katzenstein, T., Pressler, T., Ritz, C., Mathiesen, I. H. M. & Faurholt-Jepsen, D., 2020, In: P L o S One. 15, 9, 12 p., e0238524.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The origin of extracellular DNA in bacterial biofilm infections in vivo

    Alhede, M., Alhede, M., Qvortrup, Klaus, Kragh, Kasper Nørskov, Jensen, Peter Østrup, Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Pathogens and Disease. ftaa018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2019
  38. Published

    ADDITION OF GLUCOSE PROVIDES MYCOBACTERIUM ABSCESSUS BIOFILM WITH PROTECTION AGAINST AMIKACIN

    Demant, M., Kristensen, S., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup & Kolpen, M., 2019, In: Pediatric Pulmonology. 54, S2, p. S298-S299

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  39. Published

    Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis

    Lerche, C. J., Christophersen, L. J., Goetze, J. P., Nielsen, P. R., Thomsen, K., Enevold, C., Høiby, Niels, Jensen, Peter Østrup, Bundgård, Henning & Moser, Claus Ernst, 2019, In: PLoS ONE. 14, 4, 16 p., e0215333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Antibiotic therapy as personalized medicine - general considerations and complicating factors

    Moser, Claus Ernst, Lerche, C. J., Thomsen, K., Hartvig, T., Schierbeck, J., Jensen, Peter Østrup, Ciofu, Oana & Høiby, Niels, 2019, In: APMIS. 127, 5, p. 361-371

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms

    Crabbé, A., Jensen, Peter Østrup, Bjarnsholt, Thomas & Coenye, T., 2019, In: Trends in Microbiology. 27, 10, p. 850-863

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

    Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, Kasper Nørskov, Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air

    Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, Faurholt-jepsen, D., Høiby, Niels & Kolpen, Mette, 2019, In: Biofilm. 1, 4 p., 100008.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Markers of bone turnover are reduced in patients with CF related diabetes; the role of glucose

    Mathiesen, I. H., Hitz, Mette Friberg, Katzenstein, T. L., Oturai, P., Skov, M., Jørgensen, Niklas Rye, Jensen, Peter Østrup, Mikkelsen, C. R., Krogh-Madsen, Rikke, Pressler, T. & Faurholt-Jepsen, D., 2019, In: Journal of Cystic Fibrosis. 18, 3, p. 436-441

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Oxygen restriction generates difficult-to-culture p. Aeruginosa

    Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, Kasper Nørskov, Kolpen, Mette, Sønderholm, M., Andersson, M., Koch, A., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction

    Bjarnsholt, Thomas, Jensen, Peter Østrup & Alhede, M., 2019, In: Pathogens and Disease. 77, 5, ftz052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The inflamed sputum in lower respiratory tract infection: l-lactate levels are correlated to neutrophil accumulation

    Fredman, G., Kolpen, Mette, Hertz, F. B., Petersen, P. T., Jensen, A. V., Baunbæk-Egelund, G., Ravn, Pernille, Jensen, Peter Østrup & Faurholt-Jepsen, D., 2019, In: APMIS. 127, 2, p. 72-79

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. 2018
  49. Published

    Implants induce a new niche for microbiomes

    Jakobsen, Tim Holm, Eickhardt, S. R., Gheorghe, Alexandra Gabriella, Stenqvist, C., Sønderholm, M., Stavnsberg, C., Jensen, Peter Østrup, Odgaard, Anders, Whiteley, M., Moser, Claus Ernst, Hvolris, J., Hougen, H. P. & Bjarnsholt, Thomas, 1 Aug 2018, In: APMIS - Journal of Pathology, Microbiology and Immunology. 126, 8, p. 685-692 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor

    Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Extracellular hydrogen peroxide measurements using a flow injection system in combination with microdialysis probes – potential and challenges

    Moßhammer, Maria, Schrameyer, V., Jensen, Peter Østrup, Koren, K. & Kühl, Michael, 2018, In: Free Radical Biology & Medicine. 128, p. 111-123

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis

    Mauch, R. M., Jensen, Peter Østrup, Moser, Claus Ernst, Levy, C. E. & Høiby, Niels, 2018, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17, 2, p. 143-152

    Research output: Contribution to journalReviewResearchpeer-review

  53. Published

    Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms

    Gade, P. A. V., Olsen, T. B., Jensen, Peter Østrup, Kolpen, Mette, Høiby, Niels, Henneberg, K. Å. & Sams, T., 2018, In: PLoS ONE. 13, 6, 16 p., e0198909.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model

    Sønderholm, M., Koren, K., Wangpraseurt, D., Jensen, Peter Østrup, Kolpen, Mette, Kragh, Kasper Nørskov, Bjarnsholt, Thomas & Kühl, Michael, 2018, In: npj Biofilms and Microbiomes. 4, 11 p., 3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2017
  56. Published

    Heading for centennial anniversary and beyond

    Norrild, B., Ralfkiaer, E., Bjarnsholt, Thomas & Jensen, Peter Østrup, Dec 2017, In: APMIS. 125, 12, p. 1133-1133

    Research output: Contribution to journalEditorialResearch

  57. Published

    Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase

    Damgaard, D., Bjørn, M. E., Jensen, Peter Østrup & Nielsen, Claus Henrik, Dec 2017, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 1203-1208 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 20166228