Peter Østrup Jensen

Peter Østrup Jensen

Associate Professor


  1. 2021
  2. Published

    Delayed neutrophil recruitment allows nascent Staphylococcus aureus biofilm formation and immune evasion

    Pettygrove, B. A., Kratofil, R. M., Alhede, M., Jensen, Peter Østrup, Newton, M., Qvortrup, Klaus, Pallister, K. B., Bjarnsholt, Thomas, Kubes, P., Voyich, J. M. & Stewart, P. S., Aug 2021, In: Biomaterials. 275, 13 p., 120775.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Accepted/In press

    Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

    Thomsen, Kim, Kobayashi, O., Kishi, K., Shirai, R., Jensen, Peter Østrup, Heydorn, A., Hentzer, M., Calum, Henrik Pierre, Christophersen, L., Høiby, Niels & Moser, Claus Ernst, 2021, (Accepted/In press) In: APMIS.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Catalase protects biofilm of Staphylococcus aureus against daptomycin activity

    El Haj, C., Lichtenberg, Mads, Nielsen, K. L., Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: Antibiotics. 10, 5, 511.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Distinct contribution of hyperbaric oxygen therapy to human neutrophil function and antibiotic efficacy against Staphylococcus aureus

    Schwartz, Franziska Angelika, Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Laulund, A. S., Woetmann, Anders , Høiby, Niels & Moser, Claus Ernst, 2021, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 129, 9, p. 566-573

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Accepted/In press

    Hyperbaric oxygen treatment impacts oxidative stress markers in patients with necrotizing soft-tissue infection

    Hedetoft, Morten Friis Fiskbæk, Jensen, Peter Østrup, Moser, Claus Ernst, Vinkel, J. & Hyldegaard, O., 2021, (Accepted/In press) In: Journal of Investigative Medicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Immune Responses to Pseudomonas aeruginosa Biofilm Infections

    Moser, Claus Ernst, Jensen, Peter Østrup, Thomsen, Kim, Kolpen, M., Rybtke, M., Lauland, A. S., Trøstrup, H. & Tolker-Nielsen, Tim, 2021, In: Frontiers in Immunology. 12, 625597.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Soluble ICAM-1 is modulated by hyperbaric oxygen treatment and correlates with disease severity and mortality in patients with necrotizing soft-tissue infection

    Hedetoft, Morten Friis Fiskbæk, Moser, Claus Ernst, Jensen, Peter Østrup, Vinkel, J. & Hyldegaard, O., 2021, In: Journal of Applied Physiology. 130, 3, p. 729-736 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The Extracellular Polysaccharide Matrix of Pseudomonas aeruginosa Biofilms Is a Determinant of Polymorphonuclear Leukocyte Responses

    Rybtke, M., Jensen, Peter Østrup, Nielsen, Claus Henrik & Tolker-Nielsen, Tim, 2021, In: Infection and Immunity. 89, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2020
  11. Published

    The Extracellular Polysaccharide Matrix of Pseudomonas aeruginosa Biofilms Is a Determinant of Polymorphonuclear Leukocyte Responses

    Rybtke, M., Jensen, Peter Østrup, Nielsen, Claus Henrik, Tolker-Nielsen, Tim & Raffatellu, M. (ed.), 15 Dec 2020, In: Infection and Immunity.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Lactobacillus rhamnosus strains of oral and vaginal origin show strong antifungal activity in vitro

    Jørgensen, M. R., Rikvold, P. T., Lichtenberg, Mads, Jensen, Peter Østrup, Kragelund, Camilla & Twetman, Svante, 2020, In: Journal of Oral Microbiology. 12, 1, 8 p., 1832832.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Staphylococcus aureus augments release of matrix metalloproteinase-8 from human polymorphonuclear leukocytes

    Kirketerp-Møller, K., Bjarnsholt, Thomas, Jensen, Peter Østrup & Ågren, Magnus, 2020, In: Acta Dermato-Venereologica. 100, 15, p. 1-2 2 p., adv00232.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes

    Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, L. & Bjarnsholt, Thomas, 2020, In: Medical microbiology and immunology. 209, p. 669–680

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

    Kolpen, M., Jensen, Peter Østrup, Qvist, T., Kragh, Kasper Nørskov, Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology

    Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Human immune cell mobilization during exercise: effect of IL-6 receptor blockade

    Bay, M. L., Heywood, S., Wedell-Neergaard, A. S., Schauer, Tim, Lehrskov, L. L., Christensen, R. H., Legård, Grit Elster, Jensen, Peter Østrup, Krogh-Madsen, Rikke & Ellingsgaard, H., 2020, In: Experimental Physiology. 105, 12, p. 2086-2098 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Neutrophil count in sputum is associated with increased sputum glucose and sputum L-lactate in cystic fibrosis

    Nielsen, B. U., Kolpen, M., Jensen, Peter Østrup, Katzenstein, T., Pressler, T., Ritz, C., Mathiesen, I. H. M. & Faurholt-Jepsen, D., 2020, In: P L o S One. 15, 9, 12 p., e0238524.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The origin of extracellular DNA in bacterial biofilm infections in vivo

    Alhede, M., Alhede, M., Qvortrup, Klaus, Kragh, Kasper Nørskov, Jensen, Peter Østrup, Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Pathogens and Disease. ftaa018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2019
  22. Published

    ADDITION OF GLUCOSE PROVIDES MYCOBACTERIUM ABSCESSUS BIOFILM WITH PROTECTION AGAINST AMIKACIN

    Demant, M., Kristensen, S., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup & Kolpen, M., 2019, In: Pediatric Pulmonology. 54, S2, p. S298-S299

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis

    Lerche, C. J., Christophersen, L. J., Goetze, J. P., Nielsen, P. R., Thomsen, K., Enevold, C., Høiby, Niels, Jensen, Peter Østrup, Bundgård, Henning & Moser, Claus Ernst, 2019, In: PLoS ONE. 14, 4, 16 p., e0215333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Antibiotic therapy as personalized medicine - general considerations and complicating factors

    Moser, Claus Ernst, Lerche, C. J., Thomsen, Kim, Hartvig, T., Schierbeck, J., Jensen, Peter Østrup, Ciofu, Oana & Høiby, Niels, 2019, In: APMIS. 127, 5, p. 361-371

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms

    Crabbé, A., Jensen, Peter Østrup, Bjarnsholt, Thomas & Coenye, T., 2019, In: Trends in Microbiology. 27, 10, p. 850-863

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

    Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, Kasper Nørskov, Bjarnsholt, Thomas & Kolpen, M., 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Improving antibiotic treatment of bacterial biofilm by hyperbaric oxygen therapy: Not just hot air

    Jensen, Peter Østrup, Møller, S. A., Lerche, C. J., Moser, Claus Ernst, Bjarnsholt, Thomas, Ciofu, Oana, zmg259, zmg259, Høiby, Niels & Kolpen, M., 2019, In: Biofilm. 1, 4 p., 100008.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Markers of bone turnover are reduced in patients with CF related diabetes; the role of glucose

    Mathiesen, I. H., Hitz, Mette Friberg, Katzenstein, T. L., Oturai, P., Skov, M., Jørgensen, Niklas Rye, Jensen, Peter Østrup, Mikkelsen, C. R., Krogh-Madsen, Rikke, Pressler, T. & Faurholt-Jepsen, D., 2019, In: Journal of Cystic Fibrosis. 18, 3, p. 436-441

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Oxygen restriction generates difficult-to-culture p. Aeruginosa

    Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, Kasper Nørskov, Kolpen, M., Sønderholm, M., Andersson, M., Koch, Anders, Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction

    Bjarnsholt, Thomas, Jensen, Peter Østrup & Alhede, M., 2019, In: Pathogens and Disease. 77, 5, ftz052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The inflamed sputum in lower respiratory tract infection: l-lactate levels are correlated to neutrophil accumulation

    Fredman, G., Kolpen, M., Hertz, F. B., Petersen, P. T., Jensen, A. V., Baunbæk-Egelund, G., Ravn, Pernille, Jensen, Peter Østrup & zmg259, zmg259, 2019, In: APMIS. 127, 2, p. 72-79

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2018
  33. Published

    Implants induce a new niche for microbiomes

    Jakobsen, Tim Holm, Eickhardt, S. R., Gheorghe, A. G., Stenqvist, C., Sønderholm, M., Stavnsberg, C., Jensen, Peter Østrup, Odgaard, Anders, Whiteley, M., Moser, Claus Ernst, Hvolris, J., Hougen, H. P. & Bjarnsholt, Thomas, 1 Aug 2018, In: APMIS - Journal of Pathology, Microbiology and Immunology. 126, 8, p. 685-692 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Pseudomonas aeruginosa biofilm hampers murine central wound healing by suppression of vascular epithelial growth factor

    Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, Kim, Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Feb 2018, In: International Wound Journal. 15, 1, p. 123-132

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Extracellular hydrogen peroxide measurements using a flow injection system in combination with microdialysis probes – potential and challenges

    Moßhammer, Maria, Schrameyer, V., Jensen, Peter Østrup, Koren, K. & Kühl, Michael, 2018, In: Free Radical Biology & Medicine. 128, p. 111-123

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Mechanisms of humoral immune response against Pseudomonas aeruginosa biofilm infection in cystic fibrosis

    Mauch, R. M., Jensen, Peter Østrup, Moser, Claus Ernst, Levy, C. E. & Høiby, Niels, 2018, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17, 2, p. 143-152

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms

    Gade, P. A. V., Olsen, T. B., Jensen, Peter Østrup, Kolpen, M., Høiby, Niels, Henneberg, K. Å. & Sams, T., 2018, In: PLoS ONE. 13, 6, 16 p., e0198909.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model

    Sønderholm, M., Koren, K., Wangpraseurt, D., Jensen, Peter Østrup, Kolpen, M., Kragh, Kasper Nørskov, Bjarnsholt, Thomas & Kühl, Michael, 2018, In: NPJ biofilms and microbiomes. 4, 11 p., 3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2017
  40. Published

    Heading for centennial anniversary and beyond

    Norrild, B., Ralfkiaer, E., Bjarnsholt, Thomas & Jensen, Peter Østrup, Dec 2017, In: APMIS. 125, 12, p. 1133-1133

    Research output: Contribution to journalEditorialResearch

  41. Published

    Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase

    Damgaard, D., Bjørn, M. E., Jensen, Peter Østrup & Nielsen, Claus Henrik, Dec 2017, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 1203-1208 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Hyperbaric oxygen sensitizes anoxic Pseudomonas aeruginosa biofilm to ciprofloxacin

    Kolpen, M., Lerche, C. J., Kragh, Kasper Nørskov, Sams, T., Koren, K., Jensen, A. S., Line, L., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, Nov 2017, In: Antimicrobial Agents and Chemotherapy. 61, 11, 9 p., e01024-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines—implications for delayed wound closure?

    Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, Kim, Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Oct 2017, In: Pathogens and Disease. 75, 7, 10 p., ftx068.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    O-2 AFFECTS THE ACTIVITY OF AMIKACIN ON MYCOBACTERIUM ABSCESSUS BIOFILM

    Kolpen, M., Ravnholt, C., Qvist, T., Kragh, Kasper Nørskov, Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, Sep 2017, In: Pediatric Pulmonology. 52, S47, p. S359-S360 379.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  45. Published

    Use of Oxygen Therapies in Wound Healing: Focus on Topical and Hyperbaric Oxygen Treatment

    Gottrup, F., Dissemond, J., Baines, C., Frykberg, R., Jensen, Peter Østrup, Kot, J., Kröger, K. & Longobardi, P., 1 May 2017, In: Journal of Wound Care. 26, Sup5, p. S1-S43

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Pseudomonas aeruginosa aggregate formation in an alginate bead model system exhibits In Vivo-like characteristics

    Sønderholm, M., Kragh, Kasper Nørskov, Koren, K., Jakobsen, Tim Holm, Darch, S., Alhede, M., Jensen, Peter Østrup, Whiteley, M., Kühl, Michael & Bjarnsholt, Thomas, May 2017, In: Applied and Environmental Microbiology. 83, 9, 15 p., e00113-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Biofilms and host response - helpful or harmful

    Moser, Claus Ernst, Pedersen, H. T., Lerche, C. J., Kolpen, M., Line, L., Thomsen, Kim, Høiby, Niels & Jensen, Peter Østrup, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 320-338 19 p.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Diagnosis of biofilm infections in cystic fibrosis patients

    Høiby, Niels, Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup, Kolpen, M., Qvist, T., Aanaes, K., Pressler, T., Skov, M. & Ciofu, Oana, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 339-343 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Hyperbaric oxygen treatment augments tobramycin efficacy in experimental staphylococcus aureus endocarditis

    Lerche, C. J., Christophersen, L. J., Kolpen, M., Nielsen, P. R., Trøstrup, H., Thomsen, Kim, Hyldegaard, O., Bundgård, Henning, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Antimicrobial Agents. 50, 3, p. 406-412

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds

    Trøstrup, H., Lerche, C. J., Christophersen, L., Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2017, In: International Journal of Molecular Sciences. 18, 7, 13 p., 1359.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Microenvironmental characteristics and physiology of biofilms in chronic infections of CF patients are strongly affected by the host immune response

    Jensen, Peter Østrup, Kolpen, M., Kragh, Kasper Nørskov & Kühl, Michael, 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 276–288 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  52. Published

    Probiotic Lactobacillus reuteri has antifungal effects on oral Candida species in vitro

    Jørgensen, M. R., Kragelund, Camilla, Jensen, Peter Østrup, Keller, M. K. & Twetman, Svante, 2017, In: Journal of Oral Microbiology. 9, 1, 8 p., 1274582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    The consequences of being in an infectious biofilm – microenvironmental conditions governing antibiotic tolerance

    Sønderholm, M., Bjarnsholt, Thomas, Alhede, M., Kolpen, M., Jensen, Peter Østrup, Kühl, Michael & Kragh, Kasper Nørskov, 2017, In: International Journal of Molecular Sciences. 18, 12, 14 p., 2688.

    Research output: Contribution to journalReviewResearchpeer-review

  54. 2016
  55. Published

    Incidence of Propionibacterium acnes in initially culture-negative thioglycollate broths: a prospective cohort study at a Danish University Hospital

    Kvich, Lasse Andersson, Jensen, Peter Østrup, Justesen, U. S. & Bjarnsholt, Thomas, Nov 2016, In: Clinical Microbiology and Infection. 22, 11, p. 941-945

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils

    Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Activation of pulmonary and lymph node dendritic cells during chronic Pseudomonas aeruginosa lung infection in mice

    Damlund, D. S. M., Christophersen, L., Jensen, Peter Østrup, Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2016, In: APMIS - Journal of Pathology, Microbiology and Immunology. 124, 6, p. 500-507 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Diffusion retardation by binding of tobramycin in an alginate biofilm model

    Cao, B., Christophersen, L., Kolpen, M., Jensen, Peter Østrup, Sneppen, Kim, Høiby, Niels, Moser, Claus Ernst & Sams, T., 21 Apr 2016, In: P L o S One. 11, 4, 11 p., e0153616.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Role of multicellular aggregates in biofilm formation

    Kragh, Kasper Nørskov, Hutchison, J. B., Melaugh, G., Rodesney, C., Roberts, A. E. L., Irie, Y., Jensen, Peter Østrup, Diggle, S. P., Allen, R. J., Gordon, V. & Bjarnsholt, Thomas, 22 Mar 2016, In: mBio. 7, 2, 11 p., e00237-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model

    Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

    Kolpen, M., Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, Kasper Nørskov, Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Development of a rechargeable optical hydrogen peroxide sensor - sensor design and biological application

    Koren, K., Jensen, Peter Østrup & Kühl, Michael, 2016, In: Analyst. 141, 14, p. 4332-4339 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Reinforcement of the bactericidal effect of ciprofloxacin on Pseudomonas aeruginosa biofilm by hyperbaric oxygen treatment

    Kolpen, M., Mousavi, N., Sams, T., Bjarnsholt, Thomas, Ciofu, Oana, Moser, Claus Ernst, Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2016, In: International Journal of Antimicrobial Agents. 47, 2, p. 163–167 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  64. 2015
  65. Published

    Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis

    Lerche, C. J., Christophersen, L. J., Trøstrup, H., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Bundgaard, H., Høiby, Niels & Moser, C., 1 Dec 2015, In: European Journal of Clinical Microbiology & Infectious Diseases. 34, 12, p. 2349-2357 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

    Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Antibiofilm Properties of Acetic Acid

    Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

    Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model

    Cao, B., Christophersen, L., Thomsen, K., Sønderholm, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2015, In: The Journal of antimicrobial chemotherapy. 70, 7, p. 2057-2063 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

    Ciofu, Oana, Tolker-Nielsen, Tim, Jensen, Peter Østrup, Wang, H. & Høiby, Niels, 2015, In: Advanced Drug Delivery Reviews. 85, p. 7-23 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  71. Published

    Denitrification by cystic fibrosis pathogens - Stenotrophomonas maltophilia is dormant in sputum

    Kolpen, M., Kragh, Kasper Nørskov, Bjarnsholt, Thomas, Line, L., Hansen, C. R., Dalbøge, C. S., Hansen, N., Kühl, Michael, Høiby, Niels & Jensen, Peter Østrup, 2015, In: International Journal of Medical Microbiology. 305, 1, p. 1-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. 2014
  73. Published

    Plasmodium falciparum avoids change in erythrocytic surface expression of phagocytosis markers during inhibition of nitric oxide synthase activity

    Hempel, C., Kohnke, H., Maretty, L., Jensen, Peter Østrup, Staalsø, Trine & Kurtzhals, Jørgen, Nov 2014, In: Molecular and Biochemical Parasitology. 198, 1, p. 29-36 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation

    Brochmann, R. P., Toft, A., Ciofu, Oana, Briales, A., Kolpen, M., Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, 2014, In: International Journal of Antimicrobial Agents. 43, 2, p. 140-147 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Exhaled breath analysis using electronic nose in cystic fibrosis and primary ciliary dyskinesia patients with chronic pulmonary infections

    Joensen, O., Paff, T., Haarman, E. G., Skovgaard, I. M., Jensen, Peter Østrup, Bjarnsholt, Thomas & Nielsen, Kim G., 2014, In: PLOS ONE. 9, 12, p. 1-15 15 p., e115584.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms

    Jensen, Peter Østrup, Briales, A., Brochmann, R. P., Wang, H., Kragh, Kasper Nørskov, Kolpen, M., Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Ciofu, Oana, 2014, In: Pathogens and Disease. 70, 3, p. 440-443 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Nitric oxide production by polymorphonuclear leukocytes in infected cystic fibrosis sputum consumes oxygen

    Kolpen, M., Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Rickelt, L. F., Kühl, Michael, Hempel, C., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Clinical and Experimental Immunology. 177, 1, p. 310–319 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

    Kolpen, M., Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: PLOS ONE. 9, 1, p. e84353 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum

    Line, L., Alhede, M., Kolpen, M., Kühl, Michael, Ciofu, Oana, Bjarnsholt, Thomas, Moser, Claus Ernst, Toyofuku, M., Nomura, N., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Frontiers in Microbiology. 5, 11 p., 554.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients

    Kragh, Kasper Nørskov, Alhede, M., Jensen, Peter Østrup, Moser, Claus Ernst, Scheike, Thomas, Jacobsen, C. S., Poulsen, Steen Seier, Eickhardt-Sørensen, S. R., Trostrup, H., Christoffersen, L., Hougen, H. P., Rickelt, L. F., Kühl, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2014, In: Infection and Immunity. 82, 11, p. 4477-4486 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. 2013
  82. Published

    Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model

    Cavanagh, J. P., Granslo, H. N., Fredheim, E. A., Christophersen, L., Jensen, Peter Østrup, Thomsen, Kim, van Gennip, M., Klingenberg, C., Flaegstad, T., Moser, Claus Ernst & Alhede, M., Sep 2013, In: The Journal of antimicrobial chemotherapy. 68, 9, p. 2106-10 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Sublethal ciprofloxacin treatment leads to rapid development of high-level ciprofloxacin resistance during long-term experimental evolution of Pseudomonas aeruginosa

    Jørgensen, K. M., Wassermann, T., Jensen, Peter Østrup, Hengzuang, W., Molin, S., Høiby, Niels & Ciofu, Oana, Sep 2013, In: Antimicrobial Agents and Chemotherapy. 57, 9, p. 4215-21 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors

    Jakobsen, Tim Holm, Bjarnsholt, Thomas, Jensen, Peter Østrup, Givskov, Michael & Høiby, Niels, Jul 2013, In: Future Microbiology. 8, 7, p. 901-21 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms

    Chiang, W., Nilsson, M., Jensen, Peter Østrup, Høiby, Niels, Nielsen, T., Givskov, Michael & Tolker-Nielsen, Tim, May 2013, In: Antimicrobial Agents and Chemotherapy. 57, 5, p. 2352-61 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model

    Trøstrup, H., Thomsen, Kim, Christophersen, L. J., Hougen, H. P., Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes

    Jakobsen, Tim Holm, Hansen, M. A., Jensen, Peter Østrup, Hansen, L., Riber, Leise, Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, Klaus, Burmølle, Mette, Moser, Claus Ernst, Kühl, Michael, Ciofu, Oana, Givskov, Michael, Sørensen, Søren Johannes, Høiby, Niels & Bjarnsholt, Thomas, 2013, In: P L o S One. 8, 7, 17 p., e68484.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    The in vivo biofilm

    Bjarnsholt, Thomas, Alhede, M., Alhede, M., Eickhardt-Sørensen, S. R., Moser, Claus Ernst, Kühl, Michael, Jensen, Peter Østrup & Høiby, Niels, 2013, In: Trends in Microbiology. 21, 9, p. 466-474 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  89. 2012
  90. Published

    Genetical analysis of all Danish patients diagnosed with chronic granulomatous disease

    Jakobsen, M. A., Katzenstein, T. L., Valerius, N. H., Roos, D., Fisker, N., Mogensen, T. H., Jensen, Peter Østrup & Barington, T., Nov 2012, In: Scandinavian Journal of Immunology. 76, 5, p. 505-11 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo

    van Gennip, M., Hultqvist, L. D., Alhede, M., Qvortrup, Klaus, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Process for the manufacture of ajoene derivatives

    Bjarnsholt, Thomas, Høiby, Niels, Jensen, Peter Østrup, Phipps, R., Shanmugham, Meenakshi, S., Alhede, M., Hultqvist, L. D., Jakobsen, Tim Holm, Tanner, D., Larsen, Thomas, O. & Givskov, Michael, 14 Jun 2012, IPC No. C07C 323/ 65 A I, Patent No. WO2012076016, Priority date 8 Dec 2010, Priority No. EP20100194154

    Research output: Patent

  93. Published

    Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing

    Jakobsen, Tim Holm, van Gennip, M., Phipps, R. K., Shanmugham, M. S., Hultqvist, L. D., Alhede, M., Skindersoe, M. E., Rasmussen, T. B., Friedrich, K., Uthe, F., Jensen, Peter Østrup, Moser, Claus Ernst, Nielsen, K. F., Eberl, L., Larsen, T. O., Tanner, D. A., Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., May 2012, In: Antimicrobial Agents and Chemotherapy. 56, 5, p. 2314-25 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Bead-size directed distribution of Pseudomonas aeruginosa results in distinct inflammatory response in a mouse model of chronic lung infection

    Christophersen, L. J., Trøstrup, H., Damlund, D. S. M., Bjarnsholt, Thomas, Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, 2012, In: Experimental and clinical endocrinology. 170, 2, p. 222-30 10 p., 170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs

    Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. 2011
  97. Published

    Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis

    Aanæs, K., Rickelt, L. F., Johansen, Helle Krogh, von Buchwald, Christian, Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2011, In: Journal of Cystic Fibrosis. 10, 2, p. 114-120 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Lactate in cystic fibrosis sputum

    Bensel, T., Stotz, M., Borneff-Lipp, M., Wollschläger, B., Wienke, A., Taccetti, G., Campana, S., Meyer, K. C., Jensen, Peter Østrup, Lechner, U., Ulrich, M., Döring, G. & Worlitzsch, D., 2011, In: Journal of Cystic Fibrosis. 10, 1, p. 37-44 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm

    Alhede, M., Kragh, K. N., Qvortrup, Klaus, Allesen-Holm, M., van Gennip, M., Christensen, L. D., Jensen, Peter Østrup, Nielsen, A. K., Parsek, M., Wozniak, D., Molin, S., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2011, In: P L o S One. 6, 11, p. e27943

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Report from Eurobiofilms 2011

    Jensen, Peter Østrup & Tolker-Nielsen, Tim, 2011, In: Future Microbiology. 6, 11, p. 1237-45

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    The clinical impact of bacterial biofilms

    Høiby, Niels, Ciofu, Oana, Johansen, Helle Krogh, Song, Z., Moser, Claus Ernst, Jensen, Peter Østrup, Molin, S., Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: International Journal of Oral Science. 3, 2, p. 55-65

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    The implication of Pseudomonas aeruginosa biofilms in infections

    Rybtke, M. T., Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: Inflammation & Allergy - Drug Targets. 10, 2, p. 141-57 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. 2010
  104. Published

    Relative contribution of Prevotella intermedia and Pseudomonas aeruginosa to lung pathology in airways of patients with cystic fibrosis

    Ulrich, M., Beer, I., Braitmaier, P., Dierkes, M., Kummer, F., Krismer, B., Schumacher, U., Gräpler-Mainka, U., Riethmüller, J., Jensen, Peter Østrup, Bjarnsholt, Thomas, Høiby, Niels, Bellon, G. & Döring, G., 1 Nov 2010, In: Thorax. 65, 11, p. 978-984 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Upregulation of dendritic cells during chronic Pseudomonas aeruginosa lung infection in BALB/c mice

    Damlund, D. S. M., Jensen, Peter Østrup, Christophersen, L. J., Alhede, M., Høiby, Niels & Moser, Claus Ernst, Jun 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  106. Published

    Inflammation in Achromobacter xylosoxidans infected cystic fibrosis patients

    Hansen, C. R., Pressler, T., Nielsen, K. G., Jensen, Peter Østrup, Bjarnsholt, Thomas & Høiby, Niels, 1 Jan 2010, In: Journal of Cystic Fibrosis. 9, 1, p. 51-58 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

    Kolpen, M., Hansen, C. R., Bjarnsholt, Thomas, Moser, C., Hultqvist, L. D., van Gennip, M., Ciofu, Oana, Mandsberg, L., Kharazmi, A., Döring, G., Givskov, Michael, Høiby, Niels & Jensen, Peter Østrup, 1 Jan 2010, In: Thorax. 65, 1, p. 57-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients

    Bjarnsholt, Thomas, Jensen, Peter Østrup, Jakobsen, Tim Holm, Phipps, R., Nielsen, A. K., Rybtke, M. T., Tolker-Nielsen, Tim, Givskov, Michael, Høiby, Niels, Ciofu, Oana & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 1 Jan 2010, In: PLoS ONE. 5, 4, p. e10115

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Adaptive Immune Responses and Biofilm Infections

    Moser, Claus Ernst & Jensen, Peter Østrup, 2010, Biofilm Infections. Bjarnsholt, T., Moser, C. E., Jensen, P. Ø. & Høiby, N. (eds.). 1st ed. New York. NY. US, p. 201-214 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  110. Published

    An in vitro model of bacterial infections in wounds and other soft tissues

    Werthén, M., Henriksson, L., Jensen, Peter Østrup, Sternberg, C., Givskov, Michael & Bjarnsholt, Thomas, 2010, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 118, 2, p. 156-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published

    Biofilm Infections

    Bjarnsholt, Thomas (ed.), Moser, Claus Ernst (ed.), Jensen, Peter Østrup (ed.) & Høiby, Niels (ed.), 2010, Springer Publishing Company. 350 p.

    Research output: Book/ReportBookResearchpeer-review

  112. Published

    Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

    Burmølle, Mette, Thomsen, T. R., Fazli, Mustafa, Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

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