Thomas Bjarnsholt

Thomas Bjarnsholt

Professor

ORCID: 0000-0002-8003-7414

Publication year:
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  1. 2024
  2. E-pub ahead of print

    RNA-sequencing of paired tape-strips and skin biopsies in atopic dermatitis reveals key differences

    Fritz, Blaine Gabriel, Halling, A. S., Diaz-Pines Cort, Isabel, Christensen, M. O., Rønnstad, A. T. M., Olesen, C. M., Knudgaard, M. H., Zachariae, Claus, Heegaard, Steffen, Thyssen, Jacob Pontoppidan & Bjarnsholt, Thomas, 2024, (E-pub ahead of print) In: Allergy: European Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. E-pub ahead of print

    Antibiotic implant irrigation and deep infection: A retrospective study of 1508 patients undergoing breast reconstruction with implants

    Hemmingsen, Mathilde Nejrup, Bennedsen, A. K., Kullab, R. B., Weltz, T. K., Ørholt, M., Norlin, C. B., Kalstrup, J., Bredgaard, R., Sørensen, Søren Johannes, Bjarnsholt, Thomas, Hølmich, Lisbet Rosenkrantz, Damsgaard, T. E., Vester-Glowinski, Peter Viktor & Herly, Mikkel, 2024, (E-pub ahead of print) In: Plastic and Reconstructive Surgery. 26 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Centennial celebrations of the Danish Pasteur Society

    Høiby, Niels & Bjarnsholt, Thomas, 2024, In: APMIS. 132, 1, p. 3

    Research output: Contribution to journal › Editorial › Research

  5. E-pub ahead of print

    Novel sampling technique maintaining the two-dimensional organization of microbes during cultivation from chronic wounds: The Imprint method

    Iversen, A. K. S., Fritz, Blaine Gabriel, Hansen, M. J., Kirketerp-Møller, K., Jakobsen, Tim Holm, Bjarnsholt, Thomas & Lichtenberg, Mads, 2024, (E-pub ahead of print) In: APMIS.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. E-pub ahead of print

    Bacterial aerobic respiration is a major consumer of oxygen in sputum from patients with acute lower respiratory tract infection

    Jensen, Peter Østrup, Olsen, P., Dungu, A. M., Egelund, G. B., Jensen, A. V., Ravn, P., Lindegaard, Birgitte, Hertz, Frederik Boëtius, Bjarnsholt, Thomas, Faurholt-Jepsen, D. & Kolpen, Mette, 2024, (E-pub ahead of print) In: APMIS.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Inhibition of Pseudomonas aeruginosa quorum sensing by chemical induction of the MexEF-oprN efflux pump

    Kristensen, Rasmus, Andersen, Jens Bo, Rybtke, Morten Levin, Jansen, C. U., Fritz, Blaine Gabriel, Kiilerich, R. O., Uhd, J., Bjarnsholt, Thomas, Qvortrup, K., Tolker-Nielsen, Tim, Givskov, Michael & Jakobsen, Tim Holm, 2024, In: Antimicrobial Agents and Chemotherapy. 68, 2

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. E-pub ahead of print

    Single cells and bacterial biofilm populations in chronic wound infections

    Lichtenberg, Mads, Kirketerp-Møller, K., Kvich, Lasse Andersson, Christensen, Mads Holm, Fritz, Blaine Gabriel, Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2024, (E-pub ahead of print) In: APMIS.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Predictive metagenomic analysis identifies specific bacterial metabolic pathways in hidradenitis suppurativa tunnels

    Ring, H. C., Thorsen, J., Lilje, B., Bay, Lene, Bjarnsholt, Thomas, Fuursted, K., Saunte, Ditte Marie, Jemec, Gregor & Thomsen, Simon Francis, 2024, In: Journal of the European Academy of Dermatology and Venereology. 38, 1, p. e63-e65

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  10. 2023
  11. Published

    3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism

    Adams, Yvonne, Clausen, Anne Skovsbo, Jensen, Peter Østrup, Lager, M., Wilhelmsson, P., Henningson, A. J., Lindgren, P. E., Faurholt-Jepsen, D., Mens, H., Kraiczy, P., Kragh, K. N., Bjarnsholt, Thomas, Kjær, Andreas, Lebech, Anne-Mette & Jensen, Anja Ramstedt, 2023, In: iScience. 26, 1, 105838.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A simplified bacterial community found within the epidermis than at the epidermal surface of atopic dermatitis patients and healthy controls

    Barnes, Christopher James, Asplund, M., Clausen, M., Rasmussen, Linett, Olesen, C. M., Yüksel, Y. T., Andersen, P. S., Litman, Thomas, Holmstrøm, K., Bay, Lene, Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Agner, Tove & Hansen, Anders Johannes, 2023, In: BMC Microbiology. 23, 12 p., 273.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Protocol to assess metabolic activity of Pseudomonas aeruginosa by measuring heat flow using isothermal calorimetry

    Beilharz, K., Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim, Bjarnsholt, Thomas & Lichtenberg, Mads, 2023, In: STAR Protocols. 4, 2, 102269.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C-30 during experimental evolution requires multiple genotypic and phenotypic changes

    Bové, M., Kolpen, Mette, Lichtenberg, Mads, Bjarnsholt, Thomas & Coenye, T., 2023, In: Microbiology (United Kingdom). 169, 1, 001278.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Direct 16S/18S rRNA Gene PCR Followed by Sanger Sequencing as a Clinical Diagnostic Tool for Detection of Bacterial and Fungal Infections: a Systematic Review and Meta-Analysis

    Drevinek, P., Hollweck, R., Lorenz, M. G., Lustig, M. & Bjarnsholt, Thomas, 2023, In: Journal of clinical microbiology. 61, 9, e0033823.

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    E-cadherin and aquaporin-3 are downregulated in wound edges of human chronic wounds

    Ernstsen, C. V., Riishede, A., Iversen, A. K. S., Bay, Lene, Bjarnsholt, Thomas & Nejsum, L. N., 2023, In: APMIS. 131, 8, p. 403-409

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Reduced Skin Microbiome Diversity in Infancy Is Associated with Increased Risk of Atopic Dermatitis in High-Risk Children

    Halling, A. S., Fritz, Blaine Gabriel, Gerner, T., Rinnov, M. R., Bay, Lene, Knudgaard, M. H., Ravn, N. H., Trautner, S., Ruge, I. F., Olesen, C., Díiaz-Pinées Cort, I., Skov, Lone, Sørensen, N., Møller Rønnstad, A. T., Thomsen, Simon Francis, Egeberg, Alexander, Jakasa, I., Kezic, S., Bjarnsholt, Thomas & Thyssen, Jacob Pontoppidan, 2023, In: Journal of Investigative Dermatology. 143, 10, p. 2030-2038 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Characterization of patients with odontogenic necrotizing soft tissue infections in the head and neck area: A retrospective analysis

    Hansen, S. U., Jespersen, Frederik Viktor Bang, Markvart, Merete, Hyldegaard, Ole, Plaschke, Christina Caroline, Bjarnsholt, Thomas, Nielsen, Claus Henrik & Jensen, Simon Storgård, 2023, In: Acta Odontologica Scandinavica. 82, 1, p. 40-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Rethinking the Inoculum Used in Animal Models of Implant-Associated Osteomyelitis – The Formation and Application of Bacterial Aggregates

    Hartmann, Katrine Top, Nielsen, R. L., Mikkelsen, F. C., Ingmer, Hanne, Kvich, Lasse Andersson, Aalbæk, Bent, Odgaard, Anders, Jensen, Henrik Elvang, Lichtenberg, Mads, Bjarnsholt, Thomas & Jensen, Louise Kruse, 2023, p. 59. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  20. Published

    Pharmacokinetics of Locally Applied Antibiotic Prophylaxis for Implant-Based Breast Reconstruction

    Hemmingsen, Mathilde Nejrup, Bennedsen, A. K., Kullab, R. B., Norlin, C. B., Ørholt, M., Larsen, A., Bue, M., Lichtenberg, Mads, Hertz, Frederik Boëtius, Damsgaard, T. E., Vester-Glowinski, Peter Viktor, Sørensen, Søren Johannes, Bjarnsholt, Thomas & Herly, Mikkel, 2023, In: JAMA network open. 6, 12, 11 p., E2348414.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Cerebral abscesses with odontogenic origin: a population-based cohort study

    Jespersen, Frederik Viktor Bang, Hansen, S. U., Jensen, Simon Storgård, Omland, L. H., Helweg-Larsen, J., Bjarnsholt, Thomas, Nielsen, Claus Henrik, Ziebell, M., Bodilsen, J. & Markvart, Merete, 2023, In: Clinical Oral Investigations. 27, 7, p. 3639-364

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    What's in a name? Characteristics of clinical biofilms

    Lichtenberg, Mads, Coenye, T., Parsek, M. R., Bjarnsholt, Thomas & Jakobsen, Tim Holm, 2023, In: FEMS Microbiology Reviews. 47, 5, p. 1-8 fuad050.

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Endolysin Inhibits Skin Colonization by Patient-Derived Staphylococcus Aureus and Malignant T-Cell Activation in Cutaneous T-Cell Lymphoma

    Pallesen, E. M. H., Gluud, M., Vadivel, C. K., Buus, T. B., de Rooij, B., Zeng, Z., Ahmad, S., Willerslev-Olsen, A., Röhrig, C., Kamstrup, M. R., Bay, L., Lindahl, L., Krejsgaard, T., Geisler, C., Bonefeld, C. M., Iversen, L., Woetmann, A., Koralov, S. B., Bjarnsholt, T., Frieling, J. & 2 others, Schmelcher, M. & Ødum, Niels, 2023, In: Journal of Investigative Dermatology. 143, 9, p. 1757-1769 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Microbial Primer: In vivo biofilm

    Rumbaugh, K. P. & Bjarnsholt, Thomas, 2023, In: Microbiology (United Kingdom). 169, 12, 5 p., 001407.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Defining the temporal relationship between the skin microbiome, immune response and skin barrier function during flare and resolution of atopic dermatitis: protocol of a Danish intervention study

    Rønnstad, A. T. M., Bay, Lene, Ruge, I. F., Halling, A., Fritz, Blaine Gabriel, Jakaša, I., Luiten, R., Kezic, S., Thomsen, Simon Francis, Bjarnsholt, Thomas & Thyssen, Jacob Pontoppidan, 2023, In: BMJ Open. 13, 2, 8 p., e068395.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Biofilm formation on endovascular aneurysm repair (EVAR) grafts- a proof of concept in vitro model

    Sunnerhagen, T., Schwartz, F., Christophersen, L., Bjarnsholt, Thomas, Qvortrup, Klaus, Eldrup, Nikolaj, Vogt, K. & Moser, Claus Ernst, 2023, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 29, 12, p. 1600.e1-1600.e6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    A collagen-based layered chronic wound biofilm model for testing antimicrobial wound products

    Thaarup, Ida Clement, Lichtenberg, Mads, Nørgaard, K. T. H., Xu, Y., Lorenzen, J., Thomsen, T. R. & Bjarnsholt, Thomas, 2023, In: Wound Repair and Regeneration. 31, 4, p. 500-515

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Characterization of pig skin microbiome and appraisal as an in vivo subcutaneous injection model

    Wareham-Mathiassen, S., Pinto Glenting, V., Bay, Lene, Allesen-Holm, M., Bengtsson, H. & Bjarnsholt, Thomas, 2023, In: Laboratory Animals. 57, 2, p. 304-318

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2022
  30. Published

    The gut microbiota can orchestrate the signaling pathways in colorectal cancer

    Bennedsen, A. L. B., Furbo, S., Bjarnsholt, Thomas, Raskov, H., Gögenur, Ismail & Kvich, Lasse Andersson, 2022, In: APMIS. 130, 3, p. 121-139 19 p.

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    APMIS 2022 focus issue on human microbiome in disease and pathology

    Bjarnsholt, Thomas, Ralfkiaer, U. & Malone, M., 2022, In: APMIS. 130, 12, p. 689 1 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  32. Published

    The importance of understanding the infectious microenvironment

    Bjarnsholt, Thomas, Whiteley, M., Rumbaugh, K. P., Stewart, P. S., Jensen, Peter Østrup & Frimodt-Møller, N., 2022, In: The Lancet Infectious Diseases. 22, 3, p. e88-e92

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Biofilm antimicrobial susceptibility through an experimental evolutionary lens

    Coenye, T., Bové, M. & Bjarnsholt, Thomas, 2022, In: npj Biofilms and Microbiomes. 8, 82.

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Transcriptomic Fingerprint of Bacterial Infection in Lower Extremity Ulcers

    Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Nielsen, C. H., Kirketerp-Møller, K., Malone, M. & Bjarnsholt, Thomas, 2022, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 130, 8, p. 524-534

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Treatment of implant-associated osteomyelitis with injectable in situ-forming depot drug delivery system

    Fuglsang-Madsen, A., Henriksen, Nicole Lind, Kvich, Lasse Andersson, Birch, Julie Knippel Melsted, Hartmann, Katrine Top, Bjarnsholt, Thomas, Andresen, T. L., Jensen, Louise Kruse, Henriksen, J. R. & Hansen, A. E., 2022.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  36. Published

    Establishing a consensus on wound infection definitions

    Haesler, E., Swanson, T., Ousey, K., Larsen, D., Carville, K., Bjarnsholt, Thomas & Haesler, P., 2022, In: Journal of Wound Care. 31, S12, p. S48-S59

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: protocol for a randomised, double-blind, placebo-controlled trial (The BREAST-AB trial)

    Hemmingsen, M. N., Larsen, A., Weltz, T. K., Ørholt, M., Wiberg, S., Bennedsen, A. K., Bille, C., Carstensen, L. F., Jensen, L. T., Bredgaard, R., Koudahl, V., Schmidt, Volker-Jürgen, Vester-Glowinski, Peter Viktor, Hølmich, Lisbet Rosenkrantz, Sørensen, Søren Johannes, Bjarnsholt, Thomas, Damsgaard, Tine M Engberg & Herly, Mikkel, 2022, In: BMJ Open. 12, 9, p. e058697

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Mucoid Pseudomonas aeruginosa Can Produce Calcium-Gelled Biofilms Independent of the Matrix Components Psl and CdrA

    Jacobs, H. M., O'Neal, L., Lopatto, E., Wozniak, D. J., Bjarnsholt, Thomas & Parsek, M. R., 2022, In: Journal of Bacteriology. 204, 5

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Bacterial biofilms predominate in both acute and chronic human lung infections

    Kolpen, Mette, Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, P., Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: European Respiratory Journal. Supplement. 60, Suppl. 66, 4.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Bacterial biofilms predominate in both acute and chronic human lung infections

    Kolpen, M., Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, Pernille, Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: Thorax. 77, p. 1015–1022

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Prevalence of biofilms in acute infections challenges a longstanding paradigm

    Kolpen, M., Jensen, Peter Østrup, Faurholt-Jepsen, D. & Bjarnsholt, Thomas, 2022, In: Biofilm. 4, 100080.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The Combination of Low-Frequency Ultrasound and Antibiotics Improves the Killing of In Vitro Staphylococcus aureus and Pseudomonas aeruginosa Biofilms

    Kvich, Lasse Andersson, Christensen, M. H., Pierchala, M. K., Astafiev, K., Lou-Moeller, R. & Bjarnsholt, Thomas, 2022, In: Antibiotics. 11, 11, 1494.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Investigation of the mechanism and chemistry underlying Staphylococcus aureus' ability to inhibit Pseudomonas aeruginosa growth in vitro

    Kvich, Lasse Andersson, Crone, S. G., Christensen, M. H., Lima, R. D. C. L., Alhede, M., Alhede, M., Stærk, Dan & Bjarnsholt, Thomas, 2022, In: Journal of Bacteriology. 204, 11, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Cyclic-di-GMP signaling controls metabolic activity in Pseudomonas aeruginosa

    Lichtenberg, Mads, Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2022, In: Cell Reports. 41, 3, p. 111515 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Inoculum Concentration Influences Pseudomonas aeruginosa Phenotype and Biofilm Architecture

    Lichtenberg, Mads, Kvich, Lasse Andersson, Larsen, S. L. B., Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2022, In: Microbiology Spectrum. 10, 6

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment

    Lichtenberg, Mads, Jakobsen, Tim Holm, Kühl, Michael, Kolpen, Mette, Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: FEMS Microbiology Reviews. 46, 5, 13 p., fuac018.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    A novel Borrelia-specific real-time PCR assay is not suitable for diagnosing Lyme neuroborreliosis

    Pedersen, Regitze Renee, Kragh, K. N., Fritz, Blaine Gabriel, Ørbæk, M., Jensen, Peter Østrup, Lebech, Anne-Mette & Bjarnsholt, Thomas, 2022, In: Ticks and Tick-borne Diseases. 13, 5, 101971.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Amplicon sequencing demonstrates comparable follicular mycobiomes in patients with hidradenitis suppurativa compared with healthy controls

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Egeberg, Alexander, Ingham, Andreas, Vedel Nielsen, H., Frew, J. W., Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 7, p. e580-e583 4 p.

    Research output: Contribution to journal › Comment/debate › Research

  49. Published

    Probiotics in hidradenitis suppurativa: a potential treatment option?

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Clinical and Experimental Dermatology. 47, 1, p. 139-141 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  50. Published

    The biofilm life cycle: expanding the conceptual model of biofilm formation

    Sauer, K., Stoodley, P., Goeres, D. M., Hall-Stoodley, L., Burmølle, Mette, Stewart, P. S. & Bjarnsholt, Thomas, 2022, In: Nature Reviews Microbiology. 20, 10, p. 608-620 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  51. Published

    IWII Wound Infection in Clinical Practice consensus document: 2022 update

    Swanson, T., Ousey, K., Haesler, E., Bjarnsholt, Thomas, Carville, K., Idensohn, P., Kalan, L., Keast, D. H., Larsen, D., Percival, S., Schultz, G., Sussman, G., Waters, N. & Weir, D., 2022, In: Journal of Wound Care. 31, S12, p. S10-S21

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Biofilm Survival Strategies in Chronic Wounds

    Thaarup, Ida Clement, Iversen, A. K. S., Lichtenberg, Mads, Bjarnsholt, Thomas & Jakobsen, Tim Holm, 2022, In: Microorganisms. 10, 4, 775.

    Research output: Contribution to journal › Review › Research › peer-review

  53. Published

    Injection site microflora in persons with diabetes: why needle reuse is not associated with increased infections?

    Wareham-Mathiassen, S., Bay, Lene, Glenting, V. P., Fatima, N., Bengtsson, H. & Bjarnsholt, Thomas, 2022, In: APMIS. 130, 7, p. 404-416 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 9755066