Thomas Bjarnsholt

Thomas Bjarnsholt

Professor


  1. Published

    Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

    Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: PLOS ONE. 9, 1, p. e84353 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

    Kolpen, Mette, Hansen, C. R., Bjarnsholt, Thomas, Moser, C., Hultqvist, Louise Dahl, van Gennip, M., Ciofu, Oana, Mandsberg, L., Kharazmi, A., Döring, G., Givskov, Michael, Høiby, Niels & Jensen, Peter Østrup, 1 Jan 2010, In: Thorax. 65, 1, p. 57-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Bacterial biofilms predominate in both acute and chronic human lung infections

    Kolpen, M., Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, Pernille, Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: Thorax. 77, p. 1015–1022

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

    Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Prevalence of biofilms in acute infections challenges a longstanding paradigm

    Kolpen, M., Jensen, Peter Østrup, Faurholt-Jepsen, D. & Bjarnsholt, Thomas, 2022, In: Biofilm. 4, 100080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Increased bactericidal activity of colistin on Pseudomonas aeruginosa biofilms in anaerobic conditions

    Kolpen, Mette, Appeldorff, C. F., Brandt, S., Mousavi, N., Kragh, K. N., Aydogan, S., Uppal, H. A., Bjarnsholt, Thomas, Ciofu, Oana, Høiby, Niels & Jensen, Peter Østrup, Feb 2016, In: Pathogens and Disease. 74, 1, 7 p., ftv086.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Anaerobic bacteria in biofilm –and their tolerance to antibiotics

    Kragh, K. N., Kühl, Michael, Gregersen, A., Tvede, M., Høiby, Niels & Bjarnsholt, Thomas, 2011.

    Research output: Contribution to conferencePosterResearch

  8. Published

    Role of multicellular aggregates in biofilm formation

    Kragh, K. N., Hutchison, J. B., Melaugh, G., Rodesney, C., Roberts, A. E. L., Irie, Y., Jensen, Peter Østrup, Diggle, S. P., Allen, R. J., Gordon, V. & Bjarnsholt, Thomas, 22 Mar 2016, In: mBio. 7, 2, 11 p., e00237-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Inoculation method could impact the outcome of microbiological experiments

    Kragh, K. N., Alhede, M., Rybtke, Morten Levin, Stavnsbjerg, Camilla, Tolker-Nielsen, Tim, Whiteley, M. & Bjarnsholt, Thomas, 2018, In: Applied and Environmental Microbiology. 84, 5, 14 p., e02264-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Into the well—A close look at the complex structures of a microtiter biofilm and the crystal violet assay

    Kragh, K. N., Alhede, M., Kvich, Lasse Andersson & Bjarnsholt, Thomas, 2019, In: Biofilm. 1, 9 p., 100006.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients

    Kragh, K. N., Alhede, M., Jensen, Peter Østrup, Moser, Claus Ernst, Scheike, Thomas, Jacobsen, C. S., Poulsen, Steen Seier, Eickhardt-Sørensen, S. R., Trostrup, H., Christoffersen, L., Hougen, H. P., Rickelt, L. F., Kühl, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2014, In: Infection and Immunity. 82, 11, p. 4477-4486 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Inhibition of Pseudomonas aeruginosa quorum sensing by chemical induction of the MexEF-oprN efflux pump

    Kristensen, Rasmus, Andersen, Jens Bo, Rybtke, Morten Levin, Jansen, C. U., Fritz, Blaine Gabriel, Kiilerich, R. O., Uhd, J., Bjarnsholt, Thomas, Qvortrup, K., Tolker-Nielsen, Tim, Givskov, Michael & Jakobsen, Tim Holm, 2024, In: Antimicrobial Agents and Chemotherapy. 68, 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The Pseudomonas aeruginosa autoinducer dodecanoyl-homoserine lactone inhibits the putrescine synthesis in human cells

    Kristiansen, S., Bjarnsholt, Thomas, Adeltoft, D., Ifversen, P. & Givskov, Michael, 2008, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 116, 5, p. 361-371 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Unexpected Diagnosis of Cerebral Toxoplasmosis by 16S and D2 Large-Subunit Ribosomal DNA PCR and Sequencing

    Kruse, Alexandra Yasmin Collin, Kvich, Lasse Andersson, Eickhardt-Dalbøge, S. R., Omland, L. H., Bjarnsholt, Thomas & Moser, Claus Ernst, Jun 2015, In: Journal of Clinical Microbiology. 53, 6, p. 1983-1985 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Incidence of Propionibacterium acnes in initially culture-negative thioglycollate broths: a prospective cohort study at a Danish University Hospital

    Kvich, Lasse Andersson, Jensen, Peter Østrup, Justesen, U. S. & Bjarnsholt, Thomas, Nov 2016, In: Clinical Microbiology and Infection. 22, 11, p. 941-945

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The Combination of Low-Frequency Ultrasound and Antibiotics Improves the Killing of In Vitro Staphylococcus aureus and Pseudomonas aeruginosa Biofilms

    Kvich, Lasse Andersson, Christensen, M. H., Pierchala, M. K., Astafiev, K., Lou-Moeller, R. & Bjarnsholt, Thomas, 2022, In: Antibiotics. 11, 11, 1494.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Oxygen restriction generates difficult-to-culture p. Aeruginosa

    Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Crone, S., Kragh, K. N., Kolpen, Mette, Sønderholm, M., Andersson, M., Koch, A., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2019, In: Frontiers in Microbiology. 10, AUG, 15 p., 1992.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Biofilms and core pathogens shape the tumor microenvironment and immune phenotype in colorectal cancer

    Kvich, Lasse Andersson, Fritz, Blaine Gabriel, Zschach, Henrike, Terkelsen, Thilde Bagger, Raskov, H., Høst-Rasmussen, K., Jakobsen, M. R., Gheorghe, Alexandra Gabriella, Gögenur, Ismail & Bjarnsholt, Thomas, 2024, In: Gut Microbes. 16, 1, 2350156.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Do Mixed-Species Biofilms Dominate in Chronic Infections? Need for in situ Visualization of Bacterial Organization

    Kvich, Lasse Andersson, Burmølle, Mette, Bjarnsholt, Thomas & Lichtenberg, Mads, 2020, In: Frontiers in Cellular and Infection Microbiology. 10, 12 p., 396.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Investigation of the mechanism and chemistry underlying Staphylococcus aureus' ability to inhibit Pseudomonas aeruginosa growth in vitro

    Kvich, Lasse Andersson, Crone, S. G., Christensen, M. H., Lima, R. D. C. L., Alhede, M., Alhede, M., Stærk, Dan & Bjarnsholt, Thomas, 2022, In: Journal of Bacteriology. 204, 11, 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. E-pub ahead of print

    Single cells and bacterial biofilm populations in chronic wound infections

    Lichtenberg, Mads, Kirketerp-Møller, K., Kvich, Lasse Andersson, Christensen, Mads Holm, Fritz, Blaine Gabriel, Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2024, (E-pub ahead of print) In: APMIS.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    What's in a name? Characteristics of clinical biofilms

    Lichtenberg, Mads, Coenye, T., Parsek, M. R., Bjarnsholt, Thomas & Jakobsen, Tim Holm, 2023, In: FEMS Microbiology Reviews. 47, 5, p. 1-8 fuad050.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa

    Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Cyclic-di-GMP signaling controls metabolic activity in Pseudomonas aeruginosa

    Lichtenberg, Mads, Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2022, In: Cell Reports. 41, 3, p. 111515 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Inoculum Concentration Influences Pseudomonas aeruginosa Phenotype and Biofilm Architecture

    Lichtenberg, Mads, Kvich, Lasse Andersson, Larsen, S. L. B., Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2022, In: Microbiology Spectrum. 10, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment

    Lichtenberg, Mads, Jakobsen, Tim Holm, Kühl, Michael, Kolpen, Mette, Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: FEMS Microbiology Reviews. 46, 5, 13 p., fuac018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum

    Line, L., Alhede, M., Kolpen, Mette, Kühl, Michael, Ciofu, Oana, Bjarnsholt, Thomas, Moser, Claus Ernst, Toyofuku, M., Nomura, N., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Frontiers in Microbiology. 5, 11 p., 554.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Interspecific bacterial interactions are reflected in multispecies biofilm spatial organization

    Liu, W., Røder, Henriette Lyng, Madsen, Jonas Stenløkke, Bjarnsholt, Thomas, Sørensen, Søren Johannes & Burmølle, Mette, 2016, In: Frontiers in Microbiology. 7, 8 p., 1366.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data

    Malone, M., Bjarnsholt, Thomas, McBain, A. J., James, G. A., Stoodley, P., Leaper, D., Tachi, M., Schultz, G., Swanson, T. & Wolcott, R. D., Jan 2017, In: Journal of Wound Care. 26, 1, p. 20-25

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    Analysis of proximal bone margins in diabetic foot osteomyelitis by conventional culture, DNA sequencing and microscopy

    Malone, M., Fritz, Blaine Gabriel, Vickery, K., Schwarzer, S., Sharma, V., Biggs, N., Radzieta, M., Jeffries, T. T., Dickson, H. G., Jensen, S. O. & Bjarnsholt, Thomas, 2019, In: APMIS. 127, 10, p. 660-670 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Shaping the growth behaviour of biofilms initiated from bacterial aggregates

    Melaugh, G., Hutchison, J., Kragh, K. N., Irie, Y., Roberts, A., Bjarnsholt, Thomas, Diggle, S. P., Gordon, V. D. & Allen, R. J., 2 Mar 2016, In: P L o S One. 11, 3, 18 p., e0149683.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    In silico analyses of metagenomes from human atherosclerotic plaque samples

    Mitra, S., Drautz-Moses, D. I., Alhede, M., Maw, M. T., Liu, Y., Purbojati, R. W., Yap, Z. H., Kushwaha, K. K., Gheorghe, Alexandra Gabriella, Bjarnsholt, Thomas, Hansen, G. M., Sillesen, Henrik, Hougen, H. P., Hansen, Peter Riis, Yang, L., Tolker-Nielsen, Tim, Schuster, S. C. & Givskov, Michael, 2015, In: Microbiome. 3, p. 1-14 38.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis

    Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Novel experimental Pseudomonas aeruginosa infection model mimicking long-term host-pathogen interactions in cystic fibrosis.

    Moser, Claus Ernst, van Gennip, M., Bjarnsholt, Thomas, Jensen, P. Ø., Lee, B., Hougen, H. P., Calum, Henrik Pierre, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, p. 95-107 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

    Møller, S. A., Jensen, Peter Østrup, Høiby, Niels, Ciofu, Oana, Kragh, K. N., Bjarnsholt, Thomas & Kolpen, Mette, 2019, In: Journal of Cystic Fibrosis. 18, 5, p. 657–664

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The discovery of bacterial biofilm in patients with muscle invasive bladder cancer

    Nadler, N., Kvich, Lasse Andersson, Bjarnsholt, Thomas, Jensen, J. B., Gögenur, Ismail & Azawi, Nessn H., 2021, In: APMIS. 129, 5, p. 265-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Achromobacter Species Isolated from Cystic Fibrosis Patients Reveal Distinctly Different Biofilm Morphotypes

    Nielsen, S. M., Nørskov-Lauritsen, N., Bjarnsholt, Thomas & Meyer, R. L., Sep 2016, In: Microorganisms. 4, 3, 16 p., 33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Identification of pathogenic microorganisms directly from positive blood vials by matrix-assisted laser desorption/ionization time of flight mass spectrometry

    Nonnemann, B., Tvede, M. & Bjarnsholt, Thomas, 18 Jan 2013, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 121, 9, p. 871-877 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Heading for centennial anniversary and beyond

    Norrild, B., Ralfkiaer, E., Bjarnsholt, Thomas & Jensen, Peter Østrup, Dec 2017, In: APMIS. 125, 12, p. 1133-1133

    Research output: Contribution to journalEditorialResearch

  40. Published

    Bacterial biofilms: a possible mechanism for chronic infection in patients with lumbar disc herniation - a prospective proof-of-concept study using fluorescence in situ hybridization

    Ohrt-Nissen, S., Fritz, Blaine Gabriel, Walbom, J., Kragh, K. N., Bjarnsholt, Thomas, Dahl, Benny & Manniche, C., 2018, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 126, 5, p. 440-447 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Is pseudarthrosis after spinal instrumentation caused by a chronic infection?

    Ohrt-Nissen, S., Fritz, Blaine Gabriel, Valentin, L., Kragh, K. N., Manniche, C., Dahl, B. & Bjarnsholt, Thomas, 2019, In: European Spine Journal. 28, p. 2996–3002

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Endolysin Inhibits Skin Colonization by Patient-Derived Staphylococcus Aureus and Malignant T-Cell Activation in Cutaneous T-Cell Lymphoma

    Pallesen, E. M. H., Gluud, M., Vadivel, C. K., Buus, T. B., de Rooij, B., Zeng, Z., Ahmad, S., Willerslev-Olsen, A., Röhrig, C., Kamstrup, M. R., Bay, L., Lindahl, L., Krejsgaard, T., Geisler, C., Bonefeld, C. M., Iversen, L., Woetmann, A., Koralov, S. B., Bjarnsholt, T., Frieling, J. & 2 others, Schmelcher, M. & Ødum, Niels, 2023, In: Journal of Investigative Dermatology. 143, 9, p. 1757-1769 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Peptidoglycan-Binding Anchor Is a Pseudomonas aeruginosa OmpA Family Lipoprotein With Importance for Outer Membrane Vesicles, Biofilms, and the Periplasmic Shape

    Paulsson, M., Kragh, K. N., Su, Y. C., Sandblad, L., Singh, B., Bjarnsholt, Thomas & Riesbeck, K., 2021, In: Frontiers in Microbiology. 12, 639582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    A novel Borrelia-specific real-time PCR assay is not suitable for diagnosing Lyme neuroborreliosis

    Pedersen, Regitze Renee, Kragh, K. N., Fritz, Blaine Gabriel, Ørbæk, M., Jensen, Peter Østrup, Lebech, Anne-Mette & Bjarnsholt, Thomas, 2022, In: Ticks and Tick-borne Diseases. 13, 5, 101971.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Biofilm Research in Bovine Mastitis

    Pedersen, Regitze Renee, Krömker, Volker, Bjarnsholt, Thomas, Dahl-Pedersen, Kirstin, Buhl, Rikke & Jørgensen, Elin , 2021, In: Frontiers in Veterinary Science. 8, 11 p., 656810.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Delayed neutrophil recruitment allows nascent Staphylococcus aureus biofilm formation and immune evasion

    Pettygrove, B. A., Kratofil, R. M., Alhede, M., Jensen, Peter Østrup, Newton, M., Qvortrup, Klaus, Pallister, K. B., Bjarnsholt, Thomas, Kubes, P., Voyich, J. M. & Stewart, P. S., Aug 2021, In: Biomaterials. 275, 13 p., 120775.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Effects of Photoactivated Titanium Dioxide Nanopowders and Coating on Planktonic and Biofilm Growth of Pseudomonas aeruginosa

    Polo, A., Diamanti, M. V., Bjarnsholt, Thomas, Høiby, Niels, Villa, F., Pedeferri, M. P. & Cappitelli, F., 25 Jul 2011, In: Photochemistry and Photobiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Chronic pulmonary disease with Mycobacterium abscessus complex is a biofilm infection

    Qvist, T., Eickhardt-Dalbøge, S. R., Kragh, K. N., Andersen, C. B., Iversen, M., Høiby, Niels & Bjarnsholt, Thomas, Dec 2015, In: European Respiratory Journal. 46, 6, p. 1823-1826 4 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  49. Published

    Dietzia papillomatosis Bacteremia

    Rammer, P., Calum, Henrik Pierre, Moser, Claus Ernst, Björnsdóttir, M. K., Smedegaard, H., Høiby, Niels & Bjarnsholt, Thomas, Jun 2013, In: Journal of Clinical Microbiology. 51, 6, p. 1977-8 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Samspillet mellem mikrobiota og immunsystemet ved kolorektal cancer

    Raskov, H., Bjarnsholt, Thomas, Alamili, M., Kragh, K. N. & Gögenur, Ismail, 5 Nov 2018, In: Ugeskrift for Laeger. 180, 45, V04180253.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Bacterial biofilm formation inside colonic crypts may accelerate colorectal carcinogenesis

    Raskov, H., Kragh, K. N., Bjarnsholt, Thomas, Alamili, M. & Gögenur, Ismail, 17 Sep 2018, In: Clinical and Translational Medicine. 7, 4 p., 30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector

    Rasmussen, T. B., Bjarnsholt, Thomas, Skindersoe, M. E., Hentzer, M., Kristoffersen, P., Köte, M., Nielsen, J., Eberl, L. & Givskov, M., 2005, In: Journal of Bacteriology. 187, 5, p. 1799-814 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Bacterial biofilm in chronic lesions of Hidradenitis Suppurativa

    Ring, H. C., Bay, Lene, Nilsson, Carl Martin Peter, Kallenbach, K., Miller, I. M., Saunte, Ditte Marie, Bjarnsholt, Thomas, Tolker-Nielsen, Tim & Jemec, Gregor, 2017, In: British Journal of Dermatology. 176, 4, p. 993–1000

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Moderate to severe hidradenitis suppurativa patients do not have an altered bacterial composition in peripheral blood compared to healthy controls

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Saunte, Ditte Marie, Lilje, B., Bay, Lene, Theut Riis, P., Larsen, N., O'Brien Andersen, L., Vedel Nielsen, H., Miller, I. M., Bjarnsholt, Thomas, Fuursted, K. & Jemec, Gregor, 2018, In: Journal of the European Academy of Dermatology and Venereology. 32, 1, p. 125-128 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Probiotics in hidradenitis suppurativa: a potential treatment option?

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Clinical and Experimental Dermatology. 47, 1, p. 139-141 2 p.

    Research output: Contribution to journalComment/debateResearch

  56. Published

    Amplicon sequencing demonstrates comparable follicular mycobiomes in patients with hidradenitis suppurativa compared with healthy controls

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Egeberg, Alexander, Ingham, Andreas, Vedel Nielsen, H., Frew, J. W., Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 7, p. e580-e583 4 p.

    Research output: Contribution to journalComment/debateResearch

  57. Published

    Predictive Metagenomic Analysis Reveals a Role of Cutaneous Dysbiosis in the Development of Hidradenitis Suppurativa

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Jørgensen, A. H., Bay, Lene, Bjarnsholt, Thomas, Fuursted, K., Thomsen, Simon Francis & Jemec, Gregor, 2020, In: Journal of Investigative Dermatology. 140, 7, p. 1473-1476

    Research output: Contribution to journalLetterResearchpeer-review

  58. Published

    Normal Skin Microbiota is Altered in Pre-clinical Hidradenitis Suppurativa

    Ring, H. C., Bay, Lene, Kallenbach, K., Miller, I. M., Prens, E., Saunte, Ditte Marie, Bjarnsholt, Thomas & Jemec, Gregor, Feb 2017, In: Acta Dermato-Venereologica. 97, 2, p. 208-213

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published
  60. Published

    Predictive metagenomic analysis identifies specific bacterial metabolic pathways in hidradenitis suppurativa tunnels

    Ring, H. C., Thorsen, J., Lilje, B., Bay, Lene, Bjarnsholt, Thomas, Fuursted, K., Saunte, Ditte Marie, Jemec, Gregor & Thomsen, Simon Francis, 2024, In: Journal of the European Academy of Dermatology and Venereology. 38, 1, p. e63-e65

    Research output: Contribution to journalComment/debateResearchpeer-review

  61. Published

    The follicular skin microbiome in patients with hidradenitis suppurativa and healthy controls

    Ring, H. C., Thorsen, J., Saunte, Ditte Marie, Lilje, B., Bay, Lene, Riis, P. T., Larsen, N., Andersen, L. O., Nielsen, H. V., Miller, I. M., Bjarnsholt, Thomas, Fuursted, K. & Jemec, Gregor, 2017, In: JAMA Dermatology. 153, 9, p. 897-905 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    The Limitations of In Vitro Experimentation in Understanding Biofilms and Chronic Infection

    Roberts, A. E. L., Kragh, K. N., Bjarnsholt, Thomas & Diggle, S. P., 20 Nov 2015, In: Journal of Molecular Biology. 427, 23, p. 3646-3661 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  63. Published

    Detection of microorganisms involved in airway infection of cystic fibrosis patients by standard culturing 6 molecular methods

    Rudkjøbing, V., Thomsen, T. R., Nielsen, P. H., Alhede, M., Johansen, U. R., Høiby, Niels & Bjarnsholt, Thomas, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  64. Published

    The microorganisms in chronically infected end-stage and non-end-stage cystic fibrosis patients

    Rudkjøbing, V. B., Thomsen, T. R., Alhede, M., Kragh, K. N., Nielsen, P. H., Johansen, U. R., Givskov, Michael, Høiby, Niels & Bjarnsholt, Thomas, Jul 2011, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 236-244 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    True microbiota involved in chronic lung infection of cystic fibrosis patients found by culturing and 16S rRNA gene analysis

    Rudkjøbing, V. B., Thomsen, T. R., Alhede, M., Kragh, K. N., Nielsen, P. H., Johansen, U., Givskov, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2011, In: Journal of Clinical Microbiology. 49, 12, p. 4352-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections

    Rudkjøbing, V. B., Thomsen, T. R., Xu, Y., Melton-Kreft, R., Ahmed, A., Eickhardt-Dalbøge, S. R., Bjarnsholt, Thomas, Poulsen, Steen Seier, Nielsen, P. H., Earl, J. P., Ehrlich, G. D. & Moser, Claus Ernst, 8 Nov 2016, In: B M C Infectious Diseases. 16, 13 p., 652.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Microbial Primer: In vivo biofilm

    Rumbaugh, K. P. & Bjarnsholt, Thomas, 2023, In: Microbiology (United Kingdom). 169, 12, 5 p., 001407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    The implication of Pseudomonas aeruginosa biofilms in infections

    Rybtke, Morten Levin, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: Inflammation & Allergy - Drug Targets. 10, 2, p. 141-57 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Biofilms can act as plasmid reserves in the absence of plasmid specific selection

    Røder, Henriette Lyng, Trivedi, Urvish, Russel, J., Kragh, K. N., Herschend, J., Thalsø-Madsen, I., Tolker-Nielsen, Tim, Bjarnsholt, Thomas, Burmølle, Mette & Madsen, Jonas Stenløkke, 2021, In: npj Biofilms and Microbiomes. 7, 6 p., 78.

    Research output: Contribution to journalLetterResearchpeer-review

  70. Published

    Defining the temporal relationship between the skin microbiome, immune response and skin barrier function during flare and resolution of atopic dermatitis: protocol of a Danish intervention study

    Rønnstad, A. T. M., Bay, Lene, Ruge, I. F., Halling, A., Fritz, Blaine Gabriel, Jakaša, I., Luiten, R., Kezic, S., Thomsen, Simon Francis, Bjarnsholt, Thomas & Thyssen, Jacob Pontoppidan, 2023, In: BMJ Open. 13, 2, 8 p., e068395.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    The biofilm life cycle: expanding the conceptual model of biofilm formation

    Sauer, K., Stoodley, P., Goeres, D. M., Hall-Stoodley, L., Burmølle, Mette, Stewart, P. S. & Bjarnsholt, Thomas, 2022, In: Nature Reviews Microbiology. 20, 10, p. 608-620 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  72. Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein

    Schreiber, K., Boes, N., Eschbach, M., Jaensch, L., Wehland, J., Bjarnsholt, Thomas, Givskov, M., Hentzer, M. & Schobert, M., 2006, In: Journal of Bacteriology. 188, 2, p. 659-68 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Morphological evidence of biofilm in chronic obstructive sialadenitis

    Schrøder, S. A., Eickhardt, S., Bjarnsholt, Thomas, Nørgaard, T. & Homøe, Preben, 2018, In: Journal of Laryngology and Otology. 132, 7, p. 611-614 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Consensus guidelines for the identification and treatment of biofilms in chronic nonhealing wounds

    Schultz, G., Bjarnsholt, Thomas, James, G. A., Leaper, D. J., McBain, A. J., Malone, M., Stoodley, P., Swanson, T., Tachi, M. & Wolcott, R. D., Sep 2017, In: Wound Repair and Regeneration. 25, 5, p. 744-757 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    The efficacy of topical agents used in wounds for managing chronic biofilm infections: A systematic review

    Schwarzer, S., James, G. A., Goeres, D., Bjarnsholt, Thomas, Vickery, K., Percival, S. L., Stoodley, P., Schultz, G., Jensen, S. O. & Malone, M., 2020, In: Journal of Infection. 80, 3, p. 261-270

    Research output: Contribution to journalReviewResearchpeer-review

  76. Published

    Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa

    Skindersoe, M. E., Alhede, M., Phipps, R., Yang, L., Jensen, P. O., Rasmussen, T. B., Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 1 Oct 2008, In: Antimicrobial Agents and Chemotherapy. 52, 10, p. 3648-63 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Quorum sensing antagonism from marine organisms

    Skindersoe, M. E., Ettinger-Epstein, P., Rasmussen, T. B., Bjarnsholt, Thomas, de Nys, R. & Givskov, Michael, 2007, In: Marine Biotechnology. 10, 1, p. 56-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Comparison of two commercial broadrange PCR and sequencing assays for identification of bacteria in culture-negative clinical samples

    Stavnsbjerg, Camilla, Frimodt-Moller, N., Moser, C. E. & Bjarnsholt, Thomas, 27 Mar 2017, In: B M C Infectious Diseases. 17, 7 p., 233.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Methods for dynamic investigations of surface-attached in vitro bacterial and fungal biofilms

    Sternberg, C., Bjarnsholt, Thomas & Shirtliff, M., 2014, In: Methods in molecular biology (Clifton, N.J.). 1147, p. 3-22 20 p.

    Research output: Contribution to journalJournal articleResearch

  80. Published

    Risk factors for chronic biofilm-related infection associated with implanted medical devices

    Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Clinical Microbiology and Infection. 26, 8, p. 1034-1038

    Research output: Contribution to journalReviewResearchpeer-review

  81. Published

    Biofilm formation on endovascular aneurysm repair (EVAR) grafts- a proof of concept in vitro model

    Sunnerhagen, T., Schwartz, F., Christophersen, L., Bjarnsholt, Thomas, Qvortrup, Klaus, Eldrup, Nikolaj, Vogt, K. & Moser, Claus Ernst, 2023, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 29, 12, p. 1600.e1-1600.e6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    IWII Wound Infection in Clinical Practice consensus document: 2022 update

    Swanson, T., Ousey, K., Haesler, E., Bjarnsholt, Thomas, Carville, K., Idensohn, P., Kalan, L., Keast, D. H., Larsen, D., Percival, S., Schultz, G., Sussman, G., Waters, N. & Weir, D., 2022, In: Journal of Wound Care. 31, S12, p. S10-S21

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Pseudomonas aeruginosa aggregate formation in an alginate bead model system exhibits In Vivo-like characteristics

    Sønderholm, M., Kragh, K. N., Koren, K., Jakobsen, Tim Holm, Darch, S., Alhede, M., Jensen, Peter Østrup, Whiteley, M., Kühl, Michael & Bjarnsholt, Thomas, May 2017, In: Applied and Environmental Microbiology. 83, 9, 15 p., e00113-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model

    Sønderholm, M., Koren, K., Wangpraseurt, D., Jensen, Peter Østrup, Kolpen, Mette, Kragh, K. N., Bjarnsholt, Thomas & Kühl, Michael, 2018, In: npj Biofilms and Microbiomes. 4, 11 p., 3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    The consequences of being in an infectious biofilm – microenvironmental conditions governing antibiotic tolerance

    Sønderholm, M., Bjarnsholt, Thomas, Alhede, M., Kolpen, Mette, Jensen, Peter Østrup, Kühl, Michael & Kragh, K. N., 2017, In: International Journal of Molecular Sciences. 18, 12, 14 p., 2688.

    Research output: Contribution to journalReviewResearchpeer-review

  86. Published

    Acetic acid and a buffer

    Bjarnsholt, Thomas, Givskov, Michael, P, H., Høiby, Niels, PO, J., HK, J. & K, K., 2010, Patent No. WO2009155931, 30 Jan 2010

    Research output: Patent

  87. Published

    A collagen-based layered chronic wound biofilm model for testing antimicrobial wound products

    Thaarup, Ida Clement, Lichtenberg, Mads, Nørgaard, K. T. H., Xu, Y., Lorenzen, J., Thomsen, T. R. & Bjarnsholt, Thomas, 2023, In: Wound Repair and Regeneration. 31, 4, p. 500-515

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Measuring enzymatic degradation of degradable starch microspheres using confocal laser scanning microscopy

    Thaarup, Ida Clement, Gummesson, C. & Bjarnsholt, Thomas, 2021, In: Acta Biomaterialia. 131, p. 464-471

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Current in vitro biofilm-infected chronic wound models for developing new treatment possibilities

    Thaarup, Ida Clement & Bjarnsholt, Thomas, 2021, In: Advances in Wound Care. 10, 2, p. 91-102 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Biofilm Survival Strategies in Chronic Wounds

    Thaarup, Ida Clement, Iversen, A. K. S., Lichtenberg, Mads, Bjarnsholt, Thomas & Jakobsen, Tim Holm, 2022, In: Microorganisms. 10, 4, 775.

    Research output: Contribution to journalReviewResearchpeer-review

  91. Published

    Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

    Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model

    Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils

    Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    The bacteriology of chronic venous leg ulcer examined by culture-independent molecular methods

    Thomsen, T. R., Aasholm, M. S., Rudkjøbing, V. B., Saunders, A. M., Bjarnsholt, Thomas, Givskov, Michael, Kirketerp-Møller, K. & Nielsen, P. H., 2010, In: Wound Repair and Regeneration. 18, 1, p. 38-49 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Bacterial micro-aggregates as inoculum in animal models of implant-associated infections

    Hartmann, Katrine Top, Lund Nielsen, R., Mikkelsen, F. C., Aalbæk, Bent, Lichtenberg, Mads, Jakobsen, Tim Holm, Bjarnsholt, Thomas, Kvich, Lasse Andersson, Ingmer, Hanne, Odgaard, Anders, Jensen, Henrik Elvang & Jensen, Louise Kruse, Jun 2024, In: Biofilm. 7, 12 p., 100200.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Bacterial micro-aggregates as inoculum in animal models of implant-associated infections

    Hartmann, Katrine Top, Lund Nielsen, R., Mikkelsen, F. C., Aalbæk, Bent, Lichtenberg, Mads, Jakobsen, Tim Holm, Bjarnsholt, Thomas, Kvich, Lasse Andersson, Ingmer, Hanne, Odgaard, Anders, Jensen, Henrik Elvang & Jensen, Louise Kruse, 2024, In: Biofilm. 7, 12 p., 100200.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. E-pub ahead of print

    What is slough? Defining the proteomic and microbial composition of slough and its implications for wound healing

    Townsend, E. C., Cheong, J. Z. A., Radzietza, M., Fritz, Blaine Gabriel, Malone, M., Bjarnsholt, Thomas, Ousey, K., Swanson, T., Schultz, G., Gibson, A. L. F. & Kalan, L. R., 2024, (E-pub ahead of print) In: Wound Repair and Regeneration.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model

    Trøstrup, H., Thomsen, K., Christophersen, L. J., Hougen, H. P., Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Relative contribution of Prevotella intermedia and Pseudomonas aeruginosa to lung pathology in airways of patients with cystic fibrosis

    Ulrich, M., Beer, I., Braitmaier, P., Dierkes, M., Kummer, F., Krismer, B., Schumacher, U., Gräpler-Mainka, U., Riethmüller, J., Jensen, Peter Østrup, Bjarnsholt, Thomas, Høiby, Niels, Bellon, G. & Döring, G., 1 Nov 2010, In: Thorax. 65, 11, p. 978-984 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Alveolar inflammation in cystic fibrosis

    Ulrich, M., Worlitzsch, D., Viglio, S., Siegmann, N., Iadarola, P., Shute, J. K., Geiser, M., Pier, G. B., Friedel, G., Barr, M. L., Schuster, A., Meyer, K. C., Ratjen, F., Bjarnsholt, Thomas, Gulbins, E. & Döring, G., 2010, In: Journal of Cystic Fibrosis. 9, 3, p. 217-27 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 9755066