Thomas Bjarnsholt

Thomas Bjarnsholt

Professor


  1. Published

    Pathogenic CD8+ epidermis-resident memory T cells displace dendritic epidermal T cells in allergic dermatitis

    Gadsbøll, Anne-Sofie Østergaard, Jee, Mia Hamilton, Funch, A. B., Alhede, M., Mraz, Veronika, Weber, Julie Friis, Callender, L. A., Carroll, E. C., Bjarnsholt, Thomas, Woetmann, Anders , Ødum, Niels, Thomsen, Allan Randrup, Johansen, Jeanne Duus, Henson, S. M., Geisler, Carsten & Bonefeld, Charlotte Menne, 2020, In: The Journal of Investigative Dermatology. 140, 4, p. 806-815.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Visualization of the in vivo interaction of a P. aeruginosa biofilm & the innate host cellular response

    van Gennip, M., Christensen, L. D., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  3. Published

    Visualization of in vivo biofilm developing on silicone implants and the interaction with the cellular response

    van Gennip, M., Christensen, L., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  4. Published

    Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo

    van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Qvortrup, K., Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa

    van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, Hans Petter, Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Computer-aided identification of recognized drugs as Pseudomonas aeruginosa quorum-sensing inhibitors

    Yang, L., Rybtke, M. T., Jakobsen, Tim Holm, Hentzer, M., Bjarnsholt, Thomas, Givskov, Michael & Tolker-Nielsen, Tim, 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2432-43 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Direct sequencing and RipSeq interpretation as a tool for identification of polymicrobial infections

    Wolff, T. Y., Eickhardt, S., Björnsdottir, M. K., Moser, Claus Ernst, Bjarnsholt, Thomas, Høiby, Niels & Thomsen, T. R., Apr 2013, In: Journal of Clinical Microbiology. 51, 4, p. 1281-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin

    Woetmann, Anders , Alhede, M., Dabelsteen, Sally, Bjarnsholt, Thomas, Rybtke, M., Nastasi, C., Krejsgaard, Thorbjørn Frej, Andersen, Mads Hald, Bonefeld, Charlotte Menne, Geisler, Carsten, Givskov, Michael & Ødum, Niels, 2018, In: OncoTarget. 9, 28, p. 19481-19489 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Mucosal biofilm detection in chronic otitis media: a study of middle ear biopsies from Greenlandic patients

    Wessman, M., Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R., Johansen, Helle Krogh & Homøe, Preben, May 2015, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 272, 5, p. 1079-1085 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    An in vitro model of bacterial infections in wounds and other soft tissues

    Werthén, M., Henriksson, L., Jensen, Peter Østrup, Sternberg, C., Givskov, Michael & Bjarnsholt, Thomas, 2010, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 118, 2, p. 156-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The phenotypic evolution of pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin

    Wassermann, T., Jørgensen, K. M., Ivanyshyn, K., Bjarnsholt, Thomas, Hossein Khademi, S. M., Jelsbak, L., Høiby, Niels & Ciofu, Oana, 1 May 2016, In: Microbiology. 162, 5, p. 865-875 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Antibiotic susceptibility of cystic fibrosis lung microbiome members in a multispecies biofilm

    Vandeplassche, E., Sass, A., Ostyn, L., Burmølle, Mette, Kragh, Kasper Nørskov, Bjarnsholt, Thomas, Coenye, T. & Crabbé, A., 2020, In: Biofilm. 2, 9 p., 100031.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes

    Van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Phipps, R., Jensen, Peter Østrup, Christophersen, L., Pamp, S. J., Moser, C., Mikkelsen, P. J., Koh, A. Y., Tolker-Nielsen, Tim, Pier, G. B., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Jul 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 7, p. 537-46 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Relative contribution of Prevotella intermedia and Pseudomonas aeruginosa to lung pathology in airways of patients with cystic fibrosis

    Ulrich, M., Beer, I., Braitmaier, P., Dierkes, M., Kummer, F., Krismer, B., Schumacher, U., Gräpler-Mainka, U., Riethmüller, J., Jensen, Peter Østrup, Bjarnsholt, Thomas, Høiby, Niels, Bellon, G. & Döring, G., 1 Nov 2010, In: Thorax. 65, 11, p. 978-984 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Alveolar inflammation in cystic fibrosis

    Ulrich, M., Worlitzsch, D., Viglio, S., Siegmann, N., Iadarola, P., Shute, J. K., Geiser, M., Pier, G. B., Friedel, G., Barr, M. L., Schuster, A., Meyer, K. C., Ratjen, F., Bjarnsholt, Thomas, Gulbins, E. & Döring, G., 2010, In: Journal of Cystic Fibrosis. 9, 3, p. 217-27 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model

    Trøstrup, H., Thomsen, Kim, Christophersen, L. J., Hougen, Hans Petter, Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The bacteriology of chronic venous leg ulcer examined by culture-independent molecular methods

    Thomsen, T. R., Aasholm, M. S., Rudkjøbing, V. B., Saunders, A. M., Bjarnsholt, Thomas, Givskov, Michael, Kirketerp-Møller, K. & Nielsen, P. H., 2010, In: Wound Repair and Regeneration. 18, 1, p. 38-49 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Anti-Pseudomonas aeruginosa IgY antibodies promote bacterial opsonization and augment the phagocytic activity of polymorphonuclear neutrophils

    Thomsen, K., Christophersen, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, Claus Ernst & Høiby, Niels, Jul 2016, In: Human Vaccines & Immunotherapeutics. 12, 7, p. 1690-1699 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

    Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Jul 2015, In: Infection and Immunity. 83, 7, p. 2686-2693 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model

    Thomsen, K., Christophersen, L., Bjarnsholt, Thomas, Jensen, Peter Østrup, Moser, Claus Ernst & Høiby, Niels, Mar 2016, In: Journal of Cystic Fibrosis. 15, 2, p. 171-178 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Current in vitro biofilm-infected chronic wound models for developing new treatment possibilities

    Thaarup, Ida Clement & Bjarnsholt, Thomas, 2021, In: Advances in Wound Care. 10, 2, p. 91-102 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Measuring enzymatic degradation of degradable starch microspheres using confocal laser scanning microscopy

    Thaarup, Ida Clement, Gummesson, C. & Bjarnsholt, Thomas, 2021, In: Acta Biomaterialia. 131, p. 464-471

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Acetic acid and a buffer

    Bjarnsholt, Thomas, Givskov, Michael, P, H., Høiby, Niels, PO, J., HK, J. & K, K., 2010, Patent No. WO2009155931, 30 Jan 2010

    Research output: Patent

  24. Published

    Pseudomonas aeruginosa aggregate formation in an alginate bead model system exhibits In Vivo-like characteristics

    Sønderholm, M., Kragh, Kasper Nørskov, Koren, K., Jakobsen, Tim Holm, Darch, S., Alhede, M., Jensen, Peter Østrup, Whiteley, M., Kühl, Michael & Bjarnsholt, Thomas, May 2017, In: Applied and Environmental Microbiology. 83, 9, 15 p., e00113-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model

    Sønderholm, M., Koren, K., Wangpraseurt, D., Jensen, Peter Østrup, Kolpen, M., Kragh, Kasper Nørskov, Bjarnsholt, Thomas & Kühl, Michael, 2018, In: NPJ biofilms and microbiomes. 4, 11 p., 3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The consequences of being in an infectious biofilm – microenvironmental conditions governing antibiotic tolerance

    Sønderholm, M., Bjarnsholt, Thomas, Alhede, M., Kolpen, M., Jensen, Peter Østrup, Kühl, Michael & Kragh, Kasper Nørskov, 2017, In: International Journal of Molecular Sciences. 18, 12, 14 p., 2688.

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    Risk factors for chronic biofilm-related infection associated with implanted medical devices

    Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Clinical Microbiology and Infection. 26, 8, p. 1034-1038

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Methods for dynamic investigations of surface-attached in vitro bacterial and fungal biofilms

    Sternberg, C., Bjarnsholt, Thomas & Shirtliff, M., 2014, In: Methods in molecular biology (Clifton, N.J.). 1147, p. 3-22 20 p.

    Research output: Contribution to journalJournal articleResearch

  29. Published

    Comparison of two commercial broadrange PCR and sequencing assays for identification of bacteria in culture-negative clinical samples

    Stavnsbjerg, Camilla, Frimodt-Moller, N., Moser, C. E. & Bjarnsholt, Thomas, 27 Mar 2017, In: B M C Infectious Diseases. 17, 7 p., 233.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Quorum sensing antagonism from marine organisms

    Skindersoe, M. E., Ettinger-Epstein, P., Rasmussen, T. B., Bjarnsholt, Thomas, de Nys, R. & Givskov, Michael, 2007, In: Marine Biotechnology. 10, 1, p. 56-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa

    Skindersoe, M. E., Alhede, M., Phipps, R., Yang, L., Jensen, P. O., Rasmussen, T. B., Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 1 Oct 2008, In: Antimicrobial Agents and Chemotherapy. 52, 10, p. 3648-63 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The efficacy of topical agents used in wounds for managing chronic biofilm infections: A systematic review

    Schwarzer, S., James, G. A., Goeres, D., Bjarnsholt, Thomas, Vickery, K., Percival, S. L., Stoodley, P., Schultz, G., Jensen, S. O. & Malone, M., 2020, In: Journal of Infection. 80, 3, p. 261-270

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Consensus guidelines for the identification and treatment of biofilms in chronic nonhealing wounds

    Schultz, G., Bjarnsholt, Thomas, James, G. A., Leaper, D. J., McBain, A. J., Malone, M., Stoodley, P., Swanson, T., Tachi, M. & Wolcott, R. D., Sep 2017, In: Wound Repair and Regeneration. 25, 5, p. 744-757 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Morphological evidence of biofilm in chronic obstructive sialadenitis

    Schrøder, S. A., Eickhardt, S., Bjarnsholt, Thomas, Nørgaard, T. & Homøe, Preben, 2018, In: Journal of Laryngology and Otology. 132, 7, p. 611-614 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein

    Schreiber, K., Boes, N., Eschbach, M., Jaensch, L., Wehland, J., Bjarnsholt, Thomas, Givskov, M., Hentzer, M. & Schobert, M., 2006, In: Journal of Bacteriology. 188, 2, p. 659-68 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Biofilms can act as plasmid reserves in the absence of plasmid specific selection

    Røder, Henriette Lyng, Trivedi, Urvish, Russel, Jakob, Kragh, Kasper Nørskov, Herschend, J., Thalsø-Madsen, I., Tolker-Nielsen, Tim, Bjarnsholt, Thomas, Burmølle, Mette & Madsen, Jonas Stenløkke, 2021, In: NPJ biofilms and microbiomes. 7, 6 p., 78.

    Research output: Contribution to journalLetterResearchpeer-review

  37. Published

    The implication of Pseudomonas aeruginosa biofilms in infections

    Rybtke, M. T., Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: Inflammation & Allergy - Drug Targets. 10, 2, p. 141-57 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    True microbiota involved in chronic lung infection of cystic fibrosis patients found by culturing and 16S rRNA gene analysis

    Rudkjøbing, V. B., Thomsen, T. R., Alhede, M., Kragh, Kasper Nørskov, Nielsen, P. H., Johansen, U., Givskov, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2011, In: Journal of Clinical Microbiology. 49, 12, p. 4352-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections

    Rudkjøbing, V. B., Thomsen, T. R., Xu, Y., Melton-Kreft, R., Ahmed, A., Eickhardt-Dalbøge, S. R., Bjarnsholt, Thomas, Poulsen, Steen Seier, Nielsen, P. H., Earl, J. P., Ehrlich, G. D. & Moser, Claus Ernst, 8 Nov 2016, In: B M C Infectious Diseases. 16, 13 p., 652.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The microorganisms in chronically infected end-stage and non-end-stage cystic fibrosis patients

    Rudkjøbing, V. B., Thomsen, T. R., Alhede, M., Kragh, Kasper Nørskov, Nielsen, P. H., Johansen, U. R., Givskov, Michael, Høiby, Niels & Bjarnsholt, Thomas, Jul 2011, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 236-244 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Detection of microorganisms involved in airway infection of cystic fibrosis patients by standard culturing 6 molecular methods

    Rudkjøbing, V., Thomsen, T. R., Nielsen, P. H., Alhede, M., Johansen, U. R., Høiby, Niels & Bjarnsholt, Thomas, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  42. Published

    The Limitations of In Vitro Experimentation in Understanding Biofilms and Chronic Infection

    Roberts, A. E. L., Kragh, Kasper Nørskov, Bjarnsholt, Thomas & Diggle, S. P., 20 Nov 2015, In: Journal of Molecular Biology. 427, 23, p. 3646-3661 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    Predictive Metagenomic Analysis Reveals a Role of Cutaneous Dysbiosis in the Development of Hidradenitis Suppurativa

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Jørgensen, A. H., Bay, Lene, Bjarnsholt, Thomas, Fuursted, K., Thomsen, Simon Francis & Jemec, Gregor, 2020, In: Journal of Investigative Dermatology. 140, 7, p. 1473-1476

    Research output: Contribution to journalLetterResearchpeer-review

  44. Published

    Normal Skin Microbiota is Altered in Pre-clinical Hidradenitis Suppurativa

    Ring, H. C., Bay, Lene, Kallenbach, K., Miller, I. M., Prens, E., Saunte, Ditte Marie, Bjarnsholt, Thomas & Jemec, Gregor, Feb 2017, In: Acta Dermato-Venereologica. 97, 2, p. 208-213

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published
  46. Published

    The follicular skin microbiome in patients with hidradenitis suppurativa and healthy controls

    Ring, H. C., Thorsen, J., Saunte, Ditte Marie, Lilje, B., Bay, Lene, Riis, P. T., Larsen, N., Andersen, L. O., Nielsen, H. V., Miller, I. M., Bjarnsholt, Thomas, Fuursted, K. & Jemec, Gregor, 2017, In: JAMA Dermatology. 153, 9, p. 897-905 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Moderate to severe hidradenitis suppurativa patients do not have an altered bacterial composition in peripheral blood compared to healthy controls

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Saunte, Ditte Marie, Lilje, B., Bay, Lene, Theut Riis, P., Larsen, N., O'Brien Andersen, L., Vedel Nielsen, H., Miller, I. M., Bjarnsholt, Thomas, Fuursted, K. & Jemec, Gregor, 2018, In: Journal of the European Academy of Dermatology and Venereology. 32, 1, p. 125-128 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Probiotics in hidradenitis suppurativa: a potential treatment option?

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Clinical and Experimental Dermatology. 47, 1, p. 139-141 2 p.

    Research output: Contribution to journalComment/debateResearch

  49. Published

    Bacterial biofilm in chronic lesions of Hidradenitis Suppurativa

    Ring, H. C., Bay, Lene, Nilsson, Carl Martin Peter, Kallenbach, K., Miller, I. M., Saunte, Ditte Marie, Bjarnsholt, Thomas, Tolker-Nielsen, Tim & Jemec, Gregor, 2017, In: British Journal of Dermatology. 176, 4, p. 993–1000

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector

    Rasmussen, T. B., Bjarnsholt, Thomas, Skindersoe, M. E., Hentzer, M., Kristoffersen, P., Köte, M., Nielsen, J., Eberl, L. & Givskov, M., 2005, In: Journal of Bacteriology. 187, 5, p. 1799-814 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 9755066