Thomas Bjarnsholt

Thomas Bjarnsholt

Professor

ORCID: 0000-0002-8003-7414

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  1. Published

    Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

    Bjarnsholt, Thomas, Jensen, P. Ø., Burmølle, M., Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, C., Molin, S., Høiby, Niels & Givskov, M. C., 1 Feb 2005, In: Microbiology. 151, Pt 2, p. 373-83 11 p.

    Research output: Contribution to journal › Journal article › peer-review

  2. The role of quorum sensing in the pathogenicity of the cunning aggressor Pseudomonas aeruginosa

    Bjarnsholt, Thomas & Givskov, M., 2006, In: Analytical and Bioanalytical Chemistry. 387, 2, p. 409-14 5 p.

    Research output: Contribution to journal › Journal article › peer-review

  3. Published

    Understanding biofilms - Are we there yet?

    Bjarnsholt, Thomas, Høiby, Niels, Donelli, G., Imbert, C. & Försberg, A., Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 125-126 2 p.

    Research output: Contribution to journal › Journal article › peer-review

  4. Published

    Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudo-monas aeruginosa infections.

    Bjarnsholt, Thomas, Jensen, P. Ø., Rasmussen, T. B., Christoffersen, L., Calum, Henrik Pierre, Hentzer, M., Hougen, H. P., Rygaard, J., Moser, Claus Ernst, Eberl, L., Høiby, Niels & Givskov, Michael, 2005, In: F E M S Microbiology. 151, p. 3873-3880 8 p.

    Research output: Contribution to journal › Journal article › peer-review

  5. Published

    APMIS 2022 focus issue on human microbiome in disease and pathology

    Bjarnsholt, Thomas, Ralfkiaer, U. & Malone, M., 2022, In: APMIS. 130, 12, p. 689 1 p.

    Research output: Contribution to journal › Editorial › peer-review

  6. Published

    Introduction to Biofilm Infections

    Bjarnsholt, Thomas, 2010, Biofilm Infections. New York

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  7. Published

    Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control

    Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 2010, In: Expert Reviews in Molecular Medicine. 12, p. e11 18 p.

    Research output: Contribution to journal › Journal article › peer-review

  8. Published

    In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect

    Bjarnsholt, Thomas, van Gennip, M., Jakobsen, Tim Holm, Hultqvist, Louise Dahl, Jensen, Peter Østrup & Givskov, Michael, 2010, In: Nature Protocols (Print Edition). 5, 2, p. 282-93 12 p.

    Research output: Contribution to journal › Journal article › peer-review

  9. Published

    Maxillary Sinus Impaction of a Core Carrier Causing Sustained Apical Periodontitis, Sinusitis, and Nasal Stenosis: A 3-year Follow-up

    Bjørndal, Lars, Amaloo, C., Markvart, Merete, Rud, V., Qvortrup, Klaus, Stavnsbjerg, Camilla & Bjarnsholt, Thomas, 18 Oct 2016, In: The Journal of Endodontics. 42, 12, p. 1851-1858 8 p.

    Research output: Contribution to journal › Journal article › peer-review

  10. Published

    Pathological and microbiological impact of a gentamicin-loaded biocomposite following limited or extensive debridement in a porcine model of osteomyelitis

    Blirup-Plum, Sophie Amalie, Bjarnsholt, Thomas, Jensen, Henrik Elvang, Kragh, K. N., Aalbæk, Bent, Gottlieb, Hans, Bue, M. & Jensen, Louise Kruse, 2020, In: Bone and Joint Research. 9, 7, p. 394-401 8 p.

    Research output: Contribution to journal › Journal article › peer-review

  11. Published

    Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection

    Bohn, Y. T., Brandes, G., Rakhimova, E., Horatzek, S., Salunkhe, P., Munder, A., van Barneveld, A., Jordan, D., Bredenbruch, F., Häussler, S., Riedel, K., Eberl, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, C., Høiby, Niels, Tümmler, B. & Wiehlmann, L., 2008, In: Molecular Microbiology. 71, 3, p. 730-47 17 p.

    Research output: Contribution to journal › Journal article › peer-review

  12. Published

    Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C-30 during experimental evolution requires multiple genotypic and phenotypic changes

    Bové, M., Kolpen, Mette, Lichtenberg, Mads, Bjarnsholt, Thomas & Coenye, T., 2023, In: Microbiology (United Kingdom). 169, 1, 001278.

    Research output: Contribution to journal › Journal article › peer-review

  13. Published

    Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation

    Brochmann, R. P., Toft, A., Ciofu, Oana, Briales, A., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, 2014, In: International Journal of Antimicrobial Agents. 43, 2, p. 140-147 8 p.

    Research output: Contribution to journal › Journal article › peer-review

  14. Published

    Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

    Burmølle, Mette, Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.

    Research output: Contribution to journal › Review › peer-review

  15. Published

    Interactions in multispecies biofilms: do they actually matter?

    Burmølle, Mette, Ren, D., Bjarnsholt, Thomas & Sørensen, Søren Johannes, 2014, In: Trends in Microbiology. 22, 2, p. 84-91 8 p.

    Research output: Contribution to journal › Review › peer-review

  16. Published

    Thermal injury induces impaired function in polymorphonuclear neutrophil granulocytes and reduced control of burn wound infection

    Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Christoffersen, L., Damlund, D. S. M., Alhede, M., Bjarnsholt, Thomas, Hougen, H. P., Givskov, Michael, Jacobsen, G. K. & Høiby, Niels, 2008, In: Clinical and Experimental Immunology. 156, 1, p. 102-110 9 p.

    Research output: Contribution to journal › Journal article › peer-review

  17. Published

    Early IL-2 treatment of mice with Pseudomonas aeruginosa pneumonia induced PMN-dominating response and reduced lung pathology

    Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Bjarnsholt, Thomas, Givskov, Michael & Høiby, Niels, 2020, In: APMIS - Journal of Pathology, Microbiology and Immunology. 128, 12, p. 647-653

    Research output: Contribution to journal › Journal article › peer-review

  18. Published

    Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model

    Cao, B., Christophersen, L., Thomsen, K., Sønderholm, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Høiby, Niels & Moser, Claus Ernst, 2015, In: The Journal of antimicrobial chemotherapy. 70, 7, p. 2057-2063 7 p.

    Research output: Contribution to journal › Journal article › peer-review

  19. Published

    A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of antimicrobial solutions and wound dressings

    Chen, X., Lorenzen, J., Xu, Y., Jonikaite, M., Thaarup, Ida Clement, Bjarnsholt, Thomas, Kirketerp-Møller, K. & Thomsen, T. R., 2021, In: Wound Repair and Regeneration. 29, 5, p. 820-829

    Research output: Contribution to journal › Journal article › peer-review

  20. Published

    Synergistic antimicrobial efficacy of furanone C30 and tobramycin against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model

    Christensen, L., van Gennip, M., Alhede, M., Kumar, N., Kjelleberg, S., Høiby, Niels, Bjarnsholt, Thomas & Givskov, M., 2010. 0 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  21. Published

    Bacterial infection as a likely cause of adverse reactions to polyacrylamide hydrogel fillers in cosmetic surgery

    Christensen, L., Breiting, V., Bjarnsholt, Thomas, Eickhardt, S., Høgdall, Estrid Vilma Solyom, Janssen, M., Pallua, N. & Zaat, S. A. J., May 2013, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 56, 10, p. 1438-44 7 p.

    Research output: Contribution to journal › Journal article › peer-review

  22. Published

    Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model

    Christensen, L., van Gennip, M., Jakobsen, Tim Holm, Alhede, M., Hougen, H. P., Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., May 2012, In: The Journal of antimicrobial chemotherapy. 67, 5, p. 1198-206 9 p.

    Research output: Contribution to journal › Journal article › peer-review

  23. Published

    Imaging N-acyl homoserine lactone quorum sensing in vivo

    Hultqvist, Louise Dahl, van Gennip, M., Jakobsen, Tim Holm, Givskov, Michael & Bjarnsholt, Thomas, 1 Jan 2011, In: Methods in Molecular Biology. 692, 2, p. 147-157 11 p.

    Research output: Contribution to journal › Journal article › peer-review

  24. Published

    Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model

    Hultqvist, Louise Dahl, Moser, C., Jensen, Peter Østrup, Rasmussen, T. B., Christophersen, L., Kjelleberg, S., Kumar, N., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2007, In: Microbiology. 153, Pt 7, p. 2312-20 8 p.

    Research output: Contribution to journal › Journal article › peer-review

  25. Published

    Bead-size directed distribution of Pseudomonas aeruginosa results in distinct inflammatory response in a mouse model of chronic lung infection

    Christophersen, L. J., Trøstrup, H., Damlund, D. S. M., Bjarnsholt, Thomas, Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, 2012, In: Experimental and clinical endocrinology. 170, 2, p. 222-30 10 p., 170.

    Research output: Contribution to journal › Journal article › peer-review

  26. Published

    Increased severity of chronic Pseuomonas aeruginosa biofilm infection in the smaller airways of BALB/C mice

    Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 0 p.

    Research output: Contribution to conference › Poster › Research › peer-review

  27. Published

    Pseudomonas aeruginosa biofilm infection in the smaller airways of BALB/c mice exacerbates pulmonary inflammation.

    Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  28. Published

    Increased severity of chronic Pseudomonas aeruginosa biofilm infection in the smaller airways of BALB/c mice

    Christophersen, L. J., Bjarnsholt, Thomas, Jensen, Peter Østrup, Damlund, D., Høiby, Niels & Moser, Claus Ernst, 2010. 0 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  29. Published

    Copper-Silver alloy coated door handles as a potential antibacterial strategy in clinical settings

    Ciacotich, N., Kvich, Lasse Andersson, Sanford, N., Wolcott, J., Bjarnsholt, Thomas & Gram, L., 2020, In: Coatings. 10, 8, 9 p., 790.

    Research output: Contribution to journal › Journal article › peer-review

  30. Published

    In Situ Monitoring of the Antibacterial Activity of a Copper-Silver Alloy Using Confocal Laser Scanning Microscopy and pH Microsensors

    Ciacotich, N., Kragh, K. N., Lichtenberg, Mads, Tesdorpf, J. E., Bjarnsholt, Thomas & Gram, L., 2019, In: Global Challenges. 3, 11, 9 p., 1900044.

    Research output: Contribution to journal › Journal article › peer-review

  31. Published

    Genetic adaptation of Pseudomonas aeruginosa during chronic lung infection of patients with cystic fibrosis: strong and weak mutators with heterogeneous genetic backgrounds emerge in mucA and/or lasR mutants

    Ciofu, Oana, Mandsberg, L. F., Bjarnsholt, Thomas, Wassermann, T. & Høiby, Niels, 2010, In: Microbiology. 156, p. 1108-1119 12 p.

    Research output: Contribution to journal › Journal article › peer-review

  32. Published

    Kinetic Model for Signal Binding to the Quorum Sensing Regulator LasR

    Claussen, A., Jakobsen, Tim Holm, Bjarnsholt, Thomas, Givskov, Michael, Welch, M., Ferkinghoff-Borg, J. & Sams, T., 2013, In: International Journal of Molecular Sciences (Online). 14, 7, p. 13360-76 17 p.

    Research output: Contribution to journal › Journal article › peer-review

  33. Published

    Should standardized susceptibility testing for microbial biofilms be introduced in clinical practice?

    Coenye, T., Goeres, D., Van Bambeke, F. & Bjarnsholt, Thomas, 2018, In: Clinical Microbiology and Infection. 24, 6, p. 570–572 3 p.

    Research output: Contribution to journal › Letter › peer-review

  34. Published

    Microbial biofilms--the coming of age of a research field

    Coenye, T., Van Dijck, P., Bjarnsholt, Thomas & Forsberg, A., Apr 2014, In: Pathogens and Disease. 70, 3, p. 203-4 2 p.

    Research output: Contribution to journal › Journal article

  35. Published

    In memoriam-Mark E. Shirtliff (1969-2018)

    Coenye, T., Bjarnsholt, Thomas, Stoodley, P. & Rumbaugh, K., 2018, In: Pathogens and Disease. 76, 7, fty068.

    Research output: Contribution to journal › Editorial

  36. Published

    The future of biofilm research – Report on the ‘2019 Biofilm Bash’

    Coenye, T., Kjellerup, B., Stoodley, P. & Bjarnsholt, Thomas, 2020, In: Biofilm. 2, 9 p., 100012.

    Research output: Contribution to journal › Comment/debate › peer-review

  37. Published

    Editorial: The complexity of microbial biofilm research-an introduction to the third thematic issue on biofilms

    Coenye, T. & Bjarnsholt, Thomas, Oct 2016, In: Pathogens and Disease. 74, 7, 2 p., ftw053.

    Research output: Contribution to journal › Editorial › peer-review

  38. Published

    Biofilm antimicrobial susceptibility through an experimental evolutionary lens

    Coenye, T., Bové, M. & Bjarnsholt, Thomas, 2022, In: npj Biofilms and Microbiomes. 8, 82.

    Research output: Contribution to journal › Review › peer-review

  39. Published

    Biofilms in wounds: a review of present knowledge

    Cooper, R. A., Bjarnsholt, Thomas & Alhede, M., Nov 2014, In: Journal of Wound Care. 23, 11, p. 570, 572-4, 576-80 passim 9 p.

    Research output: Contribution to journal › Journal article › peer-review

  40. Published

    Pseudomonas aeruginosa transcriptome during human infection

    Cornforth, D. M., Dees, J. L., Ibberson, C. B., Huse, H. K., Mathiesen, I. H., Kirketerp-Møller, K., Wolcott, R. D., Rumbaugh, K. P., Bjarnsholt, Thomas & Whiteley, M., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 22, p. E5125-E5134

    Research output: Contribution to journal › Journal article › peer-review

  41. Published

    Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms

    Crabbé, A., Jensen, Peter Østrup, Bjarnsholt, Thomas & Coenye, T., 2019, In: Trends in Microbiology. 27, 10, p. 850-863

    Research output: Contribution to journal › Review › peer-review

  42. Published

    A novel in vitro wound biofilm model used to evaluate low-frequency ultrasonic-assisted wound debridement

    Crone, S., Garde, C., Bjarnsholt, Thomas & Alhede, M., Mar 2015, In: Journal of Wound Care. 24, 2, p. 64-72 9 p.

    Research output: Contribution to journal › Journal article › peer-review

  43. Published

    The environmental occurrence of Pseudomonas aeruginosa

    Crone, S., Vives-Flórez, M., Kvich, Lasse Andersson, Saunders, A. M., Malone, M., Nicolaisen, Mette Haubjerg, Martínez-García, E., Rojas-Acosta, C., Catalina Gomez-Puerto, M., Calum, Henrik Pierre, Whiteley, M., Kolter, R. & Bjarnsholt, Thomas, 2020, In: APMIS. 128, 3, p. 220-231

    Research output: Contribution to journal › Journal article › peer-review

  44. Published

    Phage inhibit pathogen dissemination by targeting bacterial migrants in a chronic infection model

    Darch, S. E., Kragh, K. N., Abbott, E. A., Bjarnsholt, Thomas, Bull, J. J. & Whiteley, M., Mar 2017, In: mBio. 8, 2, 15 p., e00240-17.

    Research output: Contribution to journal › Journal article › peer-review

  45. Published

    A non-fatal case of invasive zygomycete (Lichtheimia corymbifera) infection in an allogeneic haematopoietic cell transplant recipient

    Eickhardt, S., Braendstrup, P., Clasen-Linde, E., Jensen, K. E., Alhede, M., Bjarnsholt, Thomas, Høiby, Niels, Vindeløv, L. & Moser, Claus Ernst, May 2013, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 121, 5, p. 456-9 4 p.

    Research output: Contribution to journal › Journal article › peer-review

  46. Published

    Autofluorescence in samples obtained from chronic biofilm infections – “all that glitters is not gold”

    Eickhardt-Dalbøge, S. R., Kragh, K. N., Schrøder, S., Poulsen, Steen Seier, Sillesen, Henrik, Givskov, Michael, Høiby, Niels, Bjarnsholt, Thomas & Alhede, M., 2015, In: Pathogens and Disease. 73, 4, 4 p., ftv012.

    Research output: Contribution to journal › Letter › peer-review

  47. Published

    Catalase protects biofilm of Staphylococcus aureus against daptomycin activity

    El Haj, C., Lichtenberg, Mads, Nielsen, K. L., Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: Antibiotics. 10, 5, 511.

    Research output: Contribution to journal › Journal article › peer-review

  48. Published

    Prevention of biofilm formation in the soft tissue filler Aquamid

    Er, Ö., Kühl, Michael, Tvede, M., Høiby, Niels, Nielsen, A. K. & Bjarnsholt, Thomas, 2011.

    Research output: Contribution to conference › Poster › Research › peer-review

  49. Published

    Dynamics of skin microbiota in shoulder surgery infections

    Fatima, N., Bjarnsholt, Thomas & Bay, Lene, 2021, In: APMIS. 129, 12, p. 665-674

    Research output: Contribution to journal › Review › peer-review

  50. Published

    Quantitative analysis of the cellular inflammatory response against biofilm bacteria in chronic wounds

    Fazli, M., Bjarnsholt, Thomas, Kirketerp-Møller, K., Jørgensen, A., Andersen, C. B., Givskov, Michael & Tolker-Nielsen, Tim, 2011, In: Wound Repair and Regeneration. 19, 3, p. 387-91 5 p.

    Research output: Contribution to journal › Journal article › peer-review

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ID: 9755066