Thomas Bjarnsholt

Thomas Bjarnsholt

Professor

ORCID: 0000-0002-8003-7414

Publication year:
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  1. 2023
  2. Published

    3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism

    Adams, Yvonne, Clausen, Anne Skovsbo, Jensen, Peter Østrup, Lager, M., Wilhelmsson, P., Henningson, A. J., Lindgren, P. E., Faurholt-Jepsen, D., Mens, H., Kraiczy, P., Kragh, K. N., Bjarnsholt, Thomas, Kjær, Andreas, Lebech, Anne-Mette & Jensen, Anja Ramstedt, 2023, In: iScience. 26, 1, 105838.

    Research output: Contribution to journal › Journal article › peer-review

  3. Published

    Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C-30 during experimental evolution requires multiple genotypic and phenotypic changes

    Bové, M., Kolpen, Mette, Lichtenberg, Mads, Bjarnsholt, Thomas & Coenye, T., 2023, In: Microbiology (United Kingdom). 169, 1, 001278.

    Research output: Contribution to journal › Journal article › peer-review

  4. Accepted/In press

    Cerebral abscesses with odontogenic origin: a population-based cohort study

    Jespersen, Frederik Viktor Bang, Hansen, S. U. B., Jensen, Simon Storgård, Omland, L. H., Helweg-Larsen, J., Bjarnsholt, Thomas, Nielsen, Claus Henrik, Ziebell, M., Bodilsen, J. & Markvart, Merete, 2023, (Accepted/In press) In: Clinical Oral Investigations.

    Research output: Contribution to journal › Journal article › peer-review

  5. Accepted/In press

    Characterization of pig skin microbiome and appraisal as an in vivo subcutaneous injection model

    Wareham-Mathiassen, S., Pinto Glenting, V., Bay, Lene, Allesen-Holm, M., Bengtsson, H. & Bjarnsholt, Thomas, 2023, (Accepted/In press) In: Laboratory Animals.

    Research output: Contribution to journal › Journal article › peer-review

  6. Published

    Defining the temporal relationship between the skin microbiome, immune response and skin barrier function during flare and resolution of atopic dermatitis: protocol of a Danish intervention study

    Rønnstad, A. T. M., Bay, Lene, Ruge, I. F., Halling, A., Fritz, Blaine Gabriel, Jakaša, I., Luiten, R., Kezic, S., Thomsen, Simon Francis, Bjarnsholt, Thomas & Thyssen, Jacob Pontoppidan, 2023, In: BMJ Open. 13, 2, 8 p., e068395.

    Research output: Contribution to journal › Journal article › peer-review

  7. Accepted/In press

    Endolysin Inhibits Skin Colonization by Patient-Derived Staphylococcus Aureus and Malignant T-Cell Activation in Cutaneous T-Cell Lymphoma

    Pallesen, E. M. H., Gluud, Maria, Vadivel, Chella Krishna, Buus, Terkild Brink, de Rooij, B., Zeng, Z., Ahmad, S., Willerslev-Olsen, A., Röhrig, C., Kamstrup, M. R., Bay, Lene, Lindahl, L., Krejsgaard, T., Geisler, Carsten, Bonefeld, C. M., Iversen, L., Woetmann, Anders , Koralov, S. B., Bjarnsholt, Thomas, Frieling, J., Schmelcher, M. & Ødum, Niels, 2023, (Accepted/In press) In: Journal of Investigative Dermatology.

    Research output: Contribution to journal › Journal article › peer-review

  8. Published

    Protocol to assess metabolic activity of Pseudomonas aeruginosa by measuring heat flow using isothermal calorimetry

    Beilharz, K., Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim, Bjarnsholt, Thomas & Lichtenberg, Mads, 2023, In: STAR Protocols. 4, 2, 102269.

    Research output: Contribution to journal › Journal article › peer-review

  9. 2022
  10. Published

    A novel Borrelia-specific real-time PCR assay is not suitable for diagnosing Lyme neuroborreliosis

    Pedersen, Regitze Renee, Kragh, K. N., Fritz, Blaine Gabriel, Ørbæk, M., Jensen, Peter Østrup, Lebech, Anne-Mette & Bjarnsholt, Thomas, 2022, In: Ticks and Tick-borne Diseases. 13, 5, 101971.

    Research output: Contribution to journal › Journal article › peer-review

  11. Published

    APMIS 2022 focus issue on human microbiome in disease and pathology

    Bjarnsholt, Thomas, Ralfkiaer, U. & Malone, M., 2022, In: APMIS. 130, 12, p. 689 1 p.

    Research output: Contribution to journal › Editorial › peer-review

  12. Published

    Amplicon sequencing demonstrates comparable follicular mycobiomes in patients with hidradenitis suppurativa compared with healthy controls

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Egeberg, Alexander, Ingham, Andreas, Vedel Nielsen, H., Frew, J. W., Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 7, p. e580-e583 4 p.

    Research output: Contribution to journal › Comment/debate

  13. Published

    Bacterial biofilms predominate in both acute and chronic human lung infections

    Kolpen, M., Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, Pernille, Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: Thorax. 77, p. 1015–1022

    Research output: Contribution to journal › Journal article › peer-review

  14. Published

    Bacterial biofilms predominate in both acute and chronic human lung infections

    Kolpen, Mette, Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, P., Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: European Respiratory Journal. Supplement. 60, Suppl. 66, 4.

    Research output: Contribution to journal › Journal article › peer-review

  15. Published

    Biofilm Survival Strategies in Chronic Wounds

    Thaarup, Ida Clement, Iversen, Anne Kristine Servais, Lichtenberg, Mads, Bjarnsholt, Thomas & Jakobsen, Tim Holm, 2022, In: Microorganisms. 10, 4, 775.

    Research output: Contribution to journal › Review › peer-review

  16. Published

    Biofilm antimicrobial susceptibility through an experimental evolutionary lens

    Coenye, T., Bové, M. & Bjarnsholt, Thomas, 2022, In: npj Biofilms and Microbiomes. 8, 82.

    Research output: Contribution to journal › Review › peer-review

  17. Published

    Cyclic-di-GMP signaling controls metabolic activity in Pseudomonas aeruginosa

    Lichtenberg, Mads, Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2022, In: Cell Reports. 41, 3, p. 111515 1 p.

    Research output: Contribution to journal › Journal article › peer-review

  18. Published

    Establishing a consensus on wound infection definitions

    Haesler, E., Swanson, T., Ousey, K., Larsen, D., Carville, K., Bjarnsholt, Thomas & Haesler, P., 2022, In: Journal of Wound Care. 31, S12, p. S48-S59

    Research output: Contribution to journal › Journal article › peer-review

  19. Published

    IWII Wound Infection in Clinical Practice consensus document: 2022 update

    Swanson, T., Ousey, K., Haesler, E., Bjarnsholt, Thomas, Carville, K., Idensohn, P., Kalan, L., Keast, D. H., Larsen, D., Percival, S., Schultz, G., Sussman, G., Waters, N. & Weir, D., 2022, In: Journal of Wound Care. 31, S12, p. S10-S21

    Research output: Contribution to journal › Journal article › peer-review

  20. Published

    Injection site microflora in persons with diabetes: why needle reuse is not associated with increased infections?

    Wareham-Mathiassen, S., Bay, Lene, Glenting, V. P., Fatima, N., Bengtsson, H. & Bjarnsholt, Thomas, 2022, In: APMIS. 130, 7, p. 404-416 13 p.

    Research output: Contribution to journal › Journal article › peer-review

  21. Published

    Inoculum Concentration Influences Pseudomonas aeruginosa Phenotype and Biofilm Architecture

    Lichtenberg, Mads, Kvich, Lasse Andersson, Larsen, S. L. B., Jakobsen, Tim Holm & Bjarnsholt, Thomas, 2022, In: Microbiology Spectrum. 10, 6

    Research output: Contribution to journal › Journal article › peer-review

  22. Published

    Investigation of the mechanism and chemistry underlying Staphylococcus aureus' ability to inhibit Pseudomonas aeruginosa growth in vitro

    Kvich, Lasse Andersson, Crone, S. G., Christensen, M. H., Lima, R. D. C. L., Alhede, M., Alhede, M., Stærk, Dan & Bjarnsholt, Thomas, 2022, In: Journal of Bacteriology. 204, 11, 16 p.

    Research output: Contribution to journal › Journal article › peer-review

  23. Published

    Mucoid Pseudomonas aeruginosa Can Produce Calcium-Gelled Biofilms Independent of the Matrix Components Psl and CdrA

    Jacobs, H. M., O'Neal, L., Lopatto, E., Wozniak, D. J., Bjarnsholt, Thomas & Parsek, M. R., 2022, In: Journal of Bacteriology. 204, 5

    Research output: Contribution to journal › Journal article › peer-review

  24. Published

    Prevalence of biofilms in acute infections challenges a longstanding paradigm

    Kolpen, M., Jensen, Peter Østrup, Faurholt-Jepsen, D. & Bjarnsholt, Thomas, 2022, In: Biofilm. 4, 100080.

    Research output: Contribution to journal › Journal article › peer-review

  25. Published

    Probiotics in hidradenitis suppurativa: a potential treatment option?

    Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Clinical and Experimental Dermatology. 47, 1, p. 139-141 2 p.

    Research output: Contribution to journal › Comment/debate

  26. Published

    Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: protocol for a randomised, double-blind, placebo-controlled trial (The BREAST-AB trial)

    Hemmingsen, M. N., Larsen, A., Weltz, T. K., Ørholt, M., Wiberg, S., Bennedsen, A. K., Bille, C., Carstensen, L. F., Jensen, L. T., Bredgaard, R., Koudahl, V., Schmidt, Volker-Jürgen, Vester-Glowinski, Peter Viktor, Hølmich, Lisbet Rosenkrantz, Sørensen, Søren Johannes, Bjarnsholt, Thomas, Damsgaard, Tine M Engberg & bxg165, bxg165, 2022, In: BMJ Open. 12, 9, p. e058697

    Research output: Contribution to journal › Journal article › peer-review

  27. Published

    The Combination of Low-Frequency Ultrasound and Antibiotics Improves the Killing of In Vitro Staphylococcus aureus and Pseudomonas aeruginosa Biofilms

    Kvich, Lasse Andersson, Christensen, M. H., Pierchala, M. K., Astafiev, K., Lou-Moeller, R. & Bjarnsholt, Thomas, 2022, In: Antibiotics. 11, 11, 1494.

    Research output: Contribution to journal › Journal article › peer-review

  28. Published

    The biofilm life cycle: expanding the conceptual model of biofilm formation

    Sauer, K., Stoodley, P., Goeres, D. M., Hall-Stoodley, L., Burmølle, Mette, Stewart, P. S. & Bjarnsholt, Thomas, 2022, In: Nature Reviews Microbiology. 20, 10, p. 608-620 13 p.

    Research output: Contribution to journal › Review › peer-review

  29. Published

    The gut microbiota can orchestrate the signaling pathways in colorectal cancer

    Bennedsen, A. L. B., Furbo, S., Bjarnsholt, Thomas, Raskov, H., Gögenur, Ismail & Kvich, Lasse Andersson, 2022, In: APMIS. 130, 3, p. 121-139 19 p.

    Research output: Contribution to journal › Review › peer-review

  30. Published

    The importance of understanding the infectious microenvironment

    Bjarnsholt, Thomas, Whiteley, M., Rumbaugh, K. P., Stewart, P. S., Jensen, Peter Østrup & Frimodt-Møller, N., 2022, In: The Lancet Infectious Diseases. 22, 3, p. e88-e92

    Research output: Contribution to journal › Review › peer-review

  31. Published

    The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment

    Lichtenberg, Mads, Jakobsen, Tim Holm, Kühl, Michael, Kolpen, Mette, Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: FEMS Microbiology Reviews. 46, 5, 13 p., fuac018.

    Research output: Contribution to journal › Journal article › peer-review

  32. Published

    Transcriptomic Fingerprint of Bacterial Infection in Lower Extremity Ulcers

    Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Nielsen, C. H., Kirketerp-Møller, K., Malone, M. & Bjarnsholt, Thomas, 2022, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 130, 8, p. 524-534

    Research output: Contribution to journal › Journal article › peer-review

  33. Published

    Treatment of implant-associated osteomyelitis with injectable in situ-forming depot drug delivery system

    Fuglsang-Madsen, A., Henriksen, Nicole Lind, Kvich, Lasse Andersson, Birch, Julie Knippel Melsted, Hartmann, Katrine Top, Bjarnsholt, Thomas, Andresen, T. L., Jensen, Louise Kruse, Henriksen, J. R. & Hansen, A. E., 2022.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  34. 2021
  35. Published

    Delayed neutrophil recruitment allows nascent Staphylococcus aureus biofilm formation and immune evasion

    Pettygrove, B. A., Kratofil, R. M., Alhede, M., Jensen, Peter Østrup, Newton, M., Qvortrup, Klaus, Pallister, K. B., Bjarnsholt, Thomas, Kubes, P., Voyich, J. M. & Stewart, P. S., Aug 2021, In: Biomaterials. 275, 13 p., 120775.

    Research output: Contribution to journal › Journal article › peer-review

  36. Published

    A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of antimicrobial solutions and wound dressings

    Chen, X., Lorenzen, J., Xu, Y., Jonikaite, M., Thaarup, Ida Clement, Bjarnsholt, Thomas, Kirketerp-Møller, K. & Thomsen, T. R., 2021, In: Wound Repair and Regeneration. 29, 5, p. 820-829

    Research output: Contribution to journal › Journal article › peer-review

  37. Published

    APMIS pandemic editorial

    Bjarnsholt, Thomas & Calum, Henrik Pierre, 2021, In: APMIS: Acta Pathologica, Microbiologica et Immunologica Scandinavica. 129, 7, p. 319 1 p.

    Research output: Contribution to journal › Editorial › peer-review

  38. Published

    Biofilm Research in Bovine Mastitis

    Pedersen, Regitze Renee, Krömker, Volker, Bjarnsholt, Thomas, Dahl-Pedersen, Kirstin, Buhl, Rikke & Jørgensen, Elin Lisby Kastbjerg, 2021, In: Frontiers in Veterinary Science. 8, 11 p., 656810.

    Research output: Contribution to journal › Journal article › peer-review

  39. Published

    Biofilm and equine limb wounds

    Jørgensen, Elin Lisby Kastbjerg, Bjarnsholt, Thomas & Jacobsen, Stine, 2021, In: Animals. 11, 10, 2825.

    Research output: Contribution to journal › Review › peer-review

  40. Published

    Biofilms can act as plasmid reserves in the absence of plasmid specific selection

    Røder, Henriette Lyng, Trivedi, Urvish, Russel, J., Kragh, K. N., Herschend, J., Thalsø-Madsen, I., Tolker-Nielsen, Tim, Bjarnsholt, Thomas, Burmølle, Mette & Madsen, Jonas Stenløkke, 2021, In: npj Biofilms and Microbiomes. 7, 6 p., 78.

    Research output: Contribution to journal › Letter › peer-review

  41. Published

    Catalase protects biofilm of Staphylococcus aureus against daptomycin activity

    El Haj, C., Lichtenberg, Mads, Nielsen, K. L., Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: Antibiotics. 10, 5, 511.

    Research output: Contribution to journal › Journal article › peer-review

  42. Published

    Current in vitro biofilm-infected chronic wound models for developing new treatment possibilities

    Thaarup, Ida Clement & Bjarnsholt, Thomas, 2021, In: Advances in Wound Care. 10, 2, p. 91-102 12 p.

    Research output: Contribution to journal › Journal article › peer-review

  43. Published

    Dynamics of skin microbiota in shoulder surgery infections

    Fatima, N., Bjarnsholt, Thomas & Bay, Lene, 2021, In: APMIS. 129, 12, p. 665-674

    Research output: Contribution to journal › Review › peer-review

  44. Published

    Measuring enzymatic degradation of degradable starch microspheres using confocal laser scanning microscopy

    Thaarup, Ida Clement, Gummesson, C. & Bjarnsholt, Thomas, 2021, In: Acta Biomaterialia. 131, p. 464-471

    Research output: Contribution to journal › Journal article › peer-review

  45. Published

    Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa

    Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, Morten Levin, Toyofuku, M., Nomura, N., Kolpen, Mette, Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.

    Research output: Contribution to journal › Journal article › peer-review

  46. Published

    Peptidoglycan-Binding Anchor Is a Pseudomonas aeruginosa OmpA Family Lipoprotein With Importance for Outer Membrane Vesicles, Biofilms, and the Periplasmic Shape

    Paulsson, M., Kragh, K. N., Su, Y. C., Sandblad, L., Singh, B., Bjarnsholt, Thomas & Riesbeck, K., 2021, In: Frontiers in Microbiology. 12, 639582.

    Research output: Contribution to journal › Journal article › peer-review

  47. Published

    Sampling challenges in diagnosis of chronic bacterial infections

    Jakobsen, Tim Holm, Xu, Y., Bay, Lene, Schønheyder, H. C., Jakobsen, T., Bjarnsholt, Thomas & Thomsen, T. R., 2021, In: Journal of Medical Microbiology. 70, 3

    Research output: Contribution to journal › Review › peer-review

  48. Published

    The discovery of bacterial biofilm in patients with muscle invasive bladder cancer

    Nadler, N., Kvich, Lasse Andersson, Bjarnsholt, Thomas, Jensen, J. B., Gögenur, Ismail & Azawi, Nessn H., 2021, In: APMIS. 129, 5, p. 265-270

    Research output: Contribution to journal › Journal article › peer-review

  49. 2020
  50. Published

    Staphylococcus aureus augments release of matrix metalloproteinase-8 from human polymorphonuclear leukocytes

    Kirketerp-Møller, K., Bjarnsholt, Thomas, Jensen, Peter Østrup & Ågren, Magnus, 2020, In: Acta Dermato-Venereologica. 100, 15, p. 1-2 2 p., adv00232.

    Research output: Contribution to journal › Journal article › peer-review

  51. Published

    Antibiotic susceptibility of cystic fibrosis lung microbiome members in a multispecies biofilm

    Vandeplassche, E., Sass, A., Ostyn, L., Burmølle, Mette, Kragh, K. N., Bjarnsholt, Thomas, Coenye, T. & Crabbé, A., 2020, In: Biofilm. 2, 9 p., 100031.

    Research output: Contribution to journal › Journal article › peer-review

  52. Published

    Bacterial aggregate size determines phagocytosis efficiency of polymorphonuclear leukocytes

    Alhede, M., Lorenz, M., Fritz, Blaine Gabriel, Jensen, Peter Østrup, Ring, H. C., Bay, Lene & Bjarnsholt, Thomas, 2020, In: Medical Microbiology and Immunology. 209, p. 669–680

    Research output: Contribution to journal › Journal article › peer-review

  53. Published

    Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

    Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

    Research output: Contribution to journal › Journal article › peer-review

  54. Published

    Copper-Silver alloy coated door handles as a potential antibacterial strategy in clinical settings

    Ciacotich, N., Kvich, Lasse Andersson, Sanford, N., Wolcott, J., Bjarnsholt, Thomas & Gram, L., 2020, In: Coatings. 10, 8, 9 p., 790.

    Research output: Contribution to journal › Journal article › peer-review

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ID: 9755066