Tim Tolker-Nielsen

Tim Tolker-Nielsen

Professor


  1. 2022
  2. Published

    Solid-phase synthesis and biological evaluation of piperazine-based novel bacterial topoisomerase inhibitors

    Flagstad, T., Pedersen, M. T., Jakobsen, Tim Holm, Felding, J., Tolker-Nielsen, Tim, Givskov, Michael, Qvortrup, K. & Nielsen, Thomas Eiland, 2022, In: Bioorganic and Medicinal Chemistry Letters. 57, 128499.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2021
  4. Published

    Biofilms can act as plasmid reserves in the absence of plasmid specific selection

    Røder, Henriette Lyng, Trivedi, Urvish, Russel, Jakob, Kragh, Kasper Nørskov, Herschend, J., Thalsø-Madsen, I., Tolker-Nielsen, Tim, Bjarnsholt, Thomas, Burmølle, Mette & Madsen, Jonas Stenløkke, 2021, In: npj Biofilms and Microbiomes. 7, 6 p., 78.

    Research output: Contribution to journalLetterResearchpeer-review

  5. Published

    Carbon starvation of Pseudomonas aeruginosa biofilms selects for dispersal insensitive mutants

    Nair, H. A. S., Subramoni, S., Poh, W. H., Hasnuddin, N. T. B., Tay, M., Givskov, Michael, Tolker-Nielsen, Tim, Kjelleberg, S., McDougald, D. & Rice, S. A., 2021, In: BMC Microbiology. 21, 10 p., 255.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through lack of the Rieske cytochrome bc1sub-unit

    Soh, E. Y. C., Smith, F., Gimenez, M. R., Yang, L., Vejborg, R. M., Fletcher, M., Halliday, N., Bleves, S., Heeb, S., Cámara, M., Givskov, Michael, Hardie, K. R., Tolker-Nielsen, Tim, Ize, B. & Williams, P., 2021, In: PLOS Pathogens. 17, 8, 25 p., e1009425.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Identification of small molecules that interfere with c-di-GMP signaling and induce dispersal of Pseudomonas aeruginosa biofilms

    Andersen, Jens Bo, Hultqvist, Louise Dahl, Jansen, C. U., Jakobsen, Tim Holm, Nilsson, Carl Martin Peter, Rybtke, M., Uhd, J., Fritz, Blaine Gabriel, Seifert, R., Berthelsen, J., Nielsen, Thomas Eiland, Qvortrup, K., Givskov, Michael & Tolker-Nielsen, Tim, 2021, In: npj Biofilms and Microbiomes. 7, 13 p., 59.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Immune Responses to Pseudomonas aeruginosa Biofilm Infections

    Moser, Claus Ernst, Jensen, Peter Østrup, Thomsen, Kim, Kolpen, M., Rybtke, M., Lauland, A. S., Trøstrup, H. & Tolker-Nielsen, Tim, 2021, In: Frontiers in Immunology. 12, 625597.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Induction of native c-di-GMP phosphodiesterases leads to dispersal of Pseudomonas aeruginosa biofilms

    Andersen, Jens Bo, Kragh, Kasper Nørskov, Hultqvist, Louise Dahl, Rybtke, M., Nilsson, Carl Martin Peter, Jakobsen, Tim Holm, Givskov, Michael & Tolker-Nielsen, Tim, 2021, In: Antimicrobial Agents and Chemotherapy. 65, 4, e02431-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Nitric-oxide-driven oxygen release in anoxic Pseudomonas aeruginosa

    Lichtenberg, Mads, Line, L., Schrameyer, V., Jakobsen, Tim Holm, Rybtke, M. L., Toyofuku, M., Nomura, N., Kolpen, M., Tolker-Nielsen, Tim, Kühl, Michael, Bjarnsholt, Thomas & Jensen, Peter Østrup, 2021, In: iScience. 24, 12, 103404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Redox protein osar (pa0056) regulates dsbm and the oxidative stress response in pseudomonas aeruginosa

    Liu, Y., Ma, Y., Ma, Z., Han, X., Qi, H., Andersen, Jens Bo, Xu, H., Tolker-Nielsen, Tim & Qiao, M., 2021, In: Antimicrobial Agents and Chemotherapy. 65, 3, e01771-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    SAR study of 4-arylazo-3,5-diamino-1: H -pyrazoles: identification of small molecules that induce dispersal of Pseudomonas aeruginosa biofilms

    Jansen, C. U., Uhd, J., Andersen, Jens Bo, Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Nilsson, Carl Martin Peter, Nielsen, Thomas Eiland, Givskov, Michael, Tolker-Nielsen, Tim & Qvortrup, K. M., 2021, In: RSC Medicinal Chemistry. 12, 11, p. 1868-1878 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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