Thomas Eiland Nielsen
Affiliate Professor
Bacteriology
Nørre Allé 14
2200 København N
- 2017
- Published
Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists
Palmer, D., Gonçalves, J. P. L., Hansen, L. V., Wu, B., Hald, H., Schoffelen, S., Diness, Frederik, Le Quement, S. T., Nielsen, Thomas Eiland & Meldal, Morten Peter, 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 8716-8730 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinase Inhibitors
Wu, P., Givskov, Michael & Nielsen, Thomas Eiland, 2017, Drug Selectivity: An Evolving Concept in Medicinal Chemistry. Wiley-Interscience, p. 33-53 21 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Scaffold Diversity from N-Acyliminium Ions
Wu, P. & Nielsen, Thomas Eiland, 2017, In: Chemical Reviews. 117, 12, p. 7811-7856 46 p.Research output: Contribution to journal › Review › Research › peer-review
- 2016
- Published
The anti-cancerous drug doxorubicin decreases the c-di-GMP content in Pseudomonas aeruginosa but promotes biofilm formation
Groizeleau, J., Rybtke, Morten Levin, Andersen, Jens Bo, Berthelsen, J., Liu, Y., Yang, L., Nielsen, Thomas Eiland, Kaever, V., Givskov, Michael & Tolker-Nielsen, Tim, 1 Oct 2016, In: Microbiology. 162, 10, p. 1797-1807 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
In vitro and in vivo generation and characterization of Pseudomonas aeruginosa biofilm-dispersed cells via c-di-GMP manipulation
Chua, S. L., Hultqvist, Louise Dahl, Yuan, M., Rybtke, Morten Levin, Nielsen, Thomas Eiland, Givskov, Michael, Tolker-Nielsen, Tim & Yang, L., Aug 2015, In: Nature Protocols (Print). 10, 8, p. 1165-80 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Synthesis of 4-halogenated 3-fluoro-6-methoxyquinolines: Key building blocks for the synthesis of antibiotics
Flagstad, T., Petersen, M. T., Hinnerfeldt, D. M., Givskov, Michael & Nielsen, Thomas Eiland, 28 Aug 2014, In: Synthesis (Germany). 46, 23, p. 3263-3267 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Identification of five structurally unrelated quorum-sensing inhibitors of Pseudomonas aeruginosa from a natural-derivative database
Tan, S. Y. Y., Chua, S. L., Chen, Y., Rice, S. A., Kjelleberg, S., Nielsen, Thomas Eiland, Yang, L. & Givskov, Michael, Nov 2013, In: Antimicrobial Agents and Chemotherapy. 57, 11, p. 5629-5641 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
A convenient procedure for the solid-phase synthesis of hydroxamic acids on PEGA resins
Nandurkar, N. S., Petersen, R., Qvortrup, K., Komnatnyy, V. V., Taveras, K. M., Le Quement, S. T., Frauenlob, R., Givskov, Michael & Nielsen, Thomas Eiland, 28 Dec 2011, In: Tetrahedron Letters. 52, 52, p. 7121-7124 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 162434453
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210
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A broad range quorum sensing inhibitor working through sRNA inhibition
Research output: Contribution to journal › Journal article › Research › peer-review
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198
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Small Molecule Anti-biofilm Agents Developed on the Basis of Mechanistic Understanding of Biofilm Formation
Research output: Contribution to journal › Review › Research › peer-review
Published -
162
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Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa
Research output: Contribution to journal › Journal article › Research › peer-review
Published