Michael Givskov
Professor
Bacteriology
Blegdamsvej 3B, 2200 København N, 22 Bygning 22, Building: 22-2-22
Member of:
- 2004
Pseudomonas aeruginosa with lasI quorum-sensing deficiency during corneal infection
Zhu, H., Bandara, R., Conibear, T. C. R., Thuruthyil, S. J., Rice, S. A., Kjelleberg, S., Givskov, Michael & Willcox, M. D. P., 2004, In: Investigative Ophthalmology & Visual Science. 45, 6, p. 1897-903 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Surface motility in Pseudomonas sp. DSS73 is required for efficient biological containment of the root-pathogenic microfungi Rhizoctonia solani and Pythium ultimum
Andersen, Jens Bo, Koch, B., Nielsen, T. H., Sørensen, D., Hansen, M., Nybroe, O., Christophersen, C., Sørensen, J., Molin, S. & Givskov, Michael, 2003, In: Microbiology. 149, Pt 1, p. 37-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics
Arevalo-Ferro, C., Hentzer, M., Reil, G., Görg, A., Kjelleberg, S., Givskov, Michael, Riedel, K. & Eberl, L., 2003, In: Environmental Microbiology. 5, 12, p. 1350-69 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum-sensing-directed protein expression in Serratia proteamaculans B5a
Christensen, A. B., Riedel, K., Eberl, L., Flodgaard, L. R., Molin, S., Gram, L. & Givskov, Michael, 2003, In: Microbiology. 149, Pt 2, p. 471-83 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors
Hentzer, M., Wu, H., Andersen, Jens Bo, Riedel, K., Rasmussen, T. B., Bagge, N., Kumar, N., Schembri, M. A., Song, Z., Kristoffersen, P., Manefield, M., Costerton, J. W., Molin, S., Eberl, L., Steinberg, P., Kjelleberg, S., Høiby, Niels & Givskov, Michael, 2003, In: EMBO Journal. 22, 15, p. 3803-15 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections
Hentzer, M. & Givskov, Michael, 2003, In: Journal of Clinical Investigation. 112, 9, p. 1300-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quorum sensing : a novel target for the treatment of biofilm infections
Hentzer, M., Eberl, L., Nielsen, J. & Givskov, Michael, 2003, In: BioDrugs. 17, 4, p. 241-50 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis of furanone-based natural product analogues with quorum sensing antagonist activity
Hjelmgaard, T., Persson, T., Rasmussen, T. B., Givskov, Michael & Nielsen, J., 2003, In: Bioorganic & Medicinal Chemistry. 11, 15, p. 3261-71 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Influence of food preservation parameters and associated microbiota on production rate, profile and stability of acylated homoserine lactones from food-derived Enterobacteriaceae
Ravn Flodgaard, L., Christensen, A. B., Molin, S., Givskov, Michael & Gram, L., 2003, In: International Journal of Food Microbiology. 84, 2, p. 145-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification and characterization of a GDSL esterase gene located proximal to the swr quorum-sensing system of Serratia liquefaciens MG1
Riedel, K., Talker-Huiber, D., Givskov, Michael, Schwab, H. & Eberl, L., 2003, In: Applied and Environmental Microbiology. 69, 7, p. 3901-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Bacterial biofilms: prokaryotic adventures in multicellularity
Webb, J. S., Givskov, Michael & Kjelleberg, S., 2003, In: Current Opinion in Microbiology. 6, 6, p. 578-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cell death in Pseudomonas aeruginosa biofilm development
Webb, J. S., Thompson, L. S., James, S., Charlton, T., Tolker-Nielsen, T., Koch, B., Givskov, Michael & Kjelleberg, S., 2003, In: Journal of Bacteriology. 185, 15, p. 4585-92 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
The identification of a tetracycline resistance gene tet(M), on a Tn916-like transposon, in the Bacillus cereus group
Agersø, Y., Jensen, L. B., Givskov, Michael & Roberts, M. C., 2002, In: FEMS Microbiology Letters. 214, 2, p. 251-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD.
Bagge, N., Ciofu, Oana, Hentzer, M., Campbell, J. I. A., Givskov, Michael & Høiby, Niels, 2002, In: Antimicrobial Agents and Chemotherapy. 46, 11, p. 3406-11 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative effects of medium hardness and nutrient availability on the swarming motility of Serratia liquefaciens
Bees, M. A., Andresén, P., Mosekilde, E. & Givskov, Michael, 2002, In: Bulletin of Mathematical Biology. 64, 3, p. 565-87 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
Food spoilage--interactions between food spoilage bacteria
Gram, L., Ravn, L., Rasch, M., Bruhn, J. B., Christensen, A. B. & Givskov, Michael, 2002, In: International Journal of Food Microbiology. 78, 1-2, p. 79-97 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound
Hentzer, M., Riedel, K., Rasmussen, T. B., Heydorn, A., Andersen, Jens Bo, Parsek, M. R., Rice, S. A., Eberl, L., Molin, S., Høiby, Niels, Kjelleberg, S. & Givskov, Michael, 2002, In: Microbiology. 148, Pt 1, p. 87-102 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting quorum sensing for treatment of chronic bacterial biofilm infections
Hentzer, M., Givskov, Michael & Parsek, M. R., 2002, In: Laboratory Medicine. 33, 4, p. 295-306 12 p.Research output: Contribution to journal › Review › Research › peer-review
Genetic analysis of functions involved in the late stages of biofilm development in Burkholderia cepacia H111
Huber, B., Riedel, K., Köthe, M., Givskov, Michael, Molin, S. & Eberl, L., 2002, In: Molecular Microbiology. 46, 2, p. 411-26 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Lipopeptide production in Pseudomonas sp. strain DSS73 is regulated by components of sugar beet seed exudate via the Gac two-component regulatory system
Koch, B., Nielsen, T. H., Sørensen, D., Andersen, J. B., Christophersen, C., Molin, S., Givskov, Michael, Sørensen, J. & Nybroe, O., 2002, In: Applied and Environmental Microbiology. 68, 9, p. 4509-16 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Lysophosphatidic acid inhibition of the accumulation of Pseudomonas aeruginosa PAO1 alginate, pyoverdin, elastase and LasA
Laux, D. C., Corson, J. M., Givskov, Michael, Hentzer, M., Møller, A., Wosencroft, K. A., Olson, J. C., Krogfelt, K. A., Goldberg, J. B. & Cohen, P., 2002, In: Microbiology. 148, Pt 6, p. 1709-23 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover
Manefield, M., Rasmussen, T. B., Henzter, M., Andersen, Jens Bo, Steinberg, P., Kjelleberg, S. & Givskov, Michael, 2002, In: Microbiology. 148, Pt 4, p. 1119-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibiotic and biosurfactant properties of cyclic lipopeptides produced by fluorescent Pseudomonas spp. from the sugar beet rhizosphere
Nielsen, T. H., Sørensen, D., Tobiasen, C., Andersen, Jens Bo, Christophersen, C., Givskov, Michael & Sørensen, J., 2002, In: Applied and Environmental Microbiology. 68, 7, p. 3416-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers
Olsen, J. A., Severinsen, R. E., Rasmussen, T. B., Hentzer, M., Givskov, Michael & Nielsen, J., 2002, In: Bioorganic & Medicinal Chemistry Letters. 12, 3, p. 325-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers
Olsen, J. A., Severinsen, R., Rasmussen, T. B., Hentzer, M., Givskov, Michael, Nielsen, J. & Nielsen, J., 11 Feb 2002, In: Bioorganic and Medicinal Chemistry Letters. 12, 3, p. 325-328 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
An attractive surface: gram-negative bacterial biofilms
Schembri, M., Givskov, Michael & Klemm, P., 2002, In: Science Signaling. 2002, 132, p. re6Research output: Contribution to journal › Journal article › Research › peer-review
Identification and characterization of an N-acylhomoserine lactone-dependent quorum-sensing system in Pseudomonas putida strain IsoF
Steidle, A., Allesen-Holm, M., Riedel, K., Berg, G., Givskov, Michael, Molin, S. & Eberl, L., 2002, In: Applied and Environmental Microbiology. 68, 12, p. 6371-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
gfp-based N-acyl homoserine-lactone sensor systems for detection of bacterial communication
Andersen, J. B., Heydorn, A., Hentzer, M., Eberl, L., Geisenberger, O., Christensen, B. B., Molin, S. & Givskov, Michael, 2001, In: Applied and Environmental Microbiology. 67, 2, p. 575-85 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Genetic and chemical tools for investigating signaling processes in biofilms
Charlton, T., Givskov, Michael, deNys, R., Andersen, Jens Bo, Hentzer, M., Rice, S. & Kjelleberg, S., 2001, In: Methods in Enzymology. 336, p. 108-28 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function
Hentzer, M., Teitzel, G. M., Balzer, G. J., Heydorn, A., Molin, S., Givskov, Michael & Parsek, M. R., 2001, In: Journal of Bacteriology. 183, 18, p. 5395-401 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility
Huber, B., Riedel, K., Hentzer, M., Heydorn, A., Gotschlich, A., Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, Pt 9, p. 2517-28 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Halogenated furanones from the red alga, Delisea pulchra, inhibit carbapenem antibiotic synthesis and exoenzyme virulence factor production in the phytopathogen Erwinia carotovora
Manefield, M., Welch, M., Givskov, Michael, Salmond, G. P. & Kjelleberg, S., 2001, In: F E M S Microbiology Letters. 205, 1, p. 131-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Methods for detecting acylated homoserine lactones produced by Gram-negative bacteria and their application in studies of AHL-production kinetics
Ravn, L., Christensen, A. B., Molin, S., Givskov, Michael & Gram, L., 2001, In: Journal of Microbiological Methods. 44, 3, p. 239-51 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
N-acyl-L-homoserine lactone-mediated regulation of the lip secretion system in Serratia liquefaciens MG1
Riedel, K., Ohnesorg, T., Krogfelt, K. A., Hansen, T. S., Omori, K., Givskov, Michael & Eberl, L., 2001, In: Journal of Bacteriology. 183, 5, p. 1805-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms
Riedel, K., Hentzer, M., Geisenberger, O., Huber, B., Steidle, A., Wu, H., Høiby, Niels, Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, Pt 12, p. 3249-62 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
N-acyl homoserinelactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms
Riedel, K., Mentzer, M., Geisenberger, O., Huber, B., Steidle, A., Wu, H., Høiby, Niels, Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, p. 3249-3262Research output: Contribution to journal › Journal article › Research › peer-review
Visualization of N-acylhomoserine lactone-mediated cell-cell communication between bacteria colonizing the tomato rhizosphere
Steidle, A., Sigl, K., Schuhegger, R., Ihring, A., Schmid, M., Gantner, S., Stoffels, M., Riedel, K., Givskov, Michael, Hartmann, A., Langebartels, C. & Eberl, L., 2001, In: Applied and Environmental Microbiology. 67, 12, p. 5761-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa mutations in lasI and rhlI quorum sensing systems result in milder chronic lung infection
Wu, H., Song, Z., Givskov, Michael, Doring, G., Worlitzsch, D., Mathee, K., Rygaard, J. & Høiby, Niels, 2001, In: Microbiology. 147, Pt 5, p. 1105-1113 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
The interaction of thin-film flow, bacterial swarming and cell differentiation in colonies of Serratia liquefaciens
Bees, M. A., Andresén, P., Mosekilde, E. & Givskov, Michael, 2000, In: Journal of Mathematical Biology. 40, 1, p. 27-63 37 p.Research output: Contribution to journal › Journal article › Research › peer-review
A novel and sensitive method for the quantification of N-3-oxoacyl homoserine lactones using gas chromatography-mass spectrometry: application to a model bacterial biofilm
Charlton, T. S., de Nys, R., Netting, A., Kumar, N., Hentzer, M., Givskov, Michael & Kjelleberg, S., 2000, In: Environmental Microbiology. 2, 5, p. 530-41 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of gltB abolishes expression of the assimilatory nitrate reductase gene (nasB) in Pseudomonas putida KT2442
Eberl, L., Ammendola, A., Rothballer, M. H., Givskov, Michael, Sternberg, C., Kilstrup, M., Schleifer, K. H. & Molin, S., 2000, In: Journal of Bacteriology. 182, 12, p. 3368-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis
Geisenberger, O., Givskov, Michael, Riedel, K., Høiby, Niels, Tümmler, B. & Eberl, L., 2000, In: F E M S Microbiology Letters. 184, 2, p. 273-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production of N-acyl-L-homoserine lactones by Pseudomonas aeruginosa isolates from chronic lung infections associated with cystic fibrosis
Geisenberger, O., Givskov, Michael, Riedel, K., Høiby, Niels, Tümmler, B. & Eberl, L., 2000, In: FEMS Microbiology Letters. 184, p. 273-278Research output: Contribution to journal › Journal article › Research › peer-review
Experimental reproducibility in flow-chamber biofilms
Heydorn, A., Ersbøll, B. K., Hentzer, M., Parsek, M. R., Givskov, Michael & Molin, S., 2000, In: Microbiology. 146 ( Pt 10), p. 2409-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantification of biofilm structures by the novel computer program COMSTAT
Heydorn, A., Nielsen, A. T., Hentzer, M., Sternberg, C., Givskov, Michael, Ersbøll, B. K. & Molin, S., 2000, In: Microbiology. 146 ( Pt 10), p. 2395-407 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Communication systems as targets for biological control
Kjelleberg, S. & Givskov, Michael, 2000, 1 ed. 1 p. (Environmental Microbiology).Research output: Book/Report › Book › Research
rpoS gene function is a disadvantage for Escherichia coli BJ4 during competitive colonization of the mouse large intestine
Krogfelt, K. A., Hjulgaard, M., Sørensen, K., Cohen, P. & Givskov, Michael, 2000, In: Infection and Immunity. 68, 5, p. 2518-24 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How Delisea pulchra furanones affect quorum sensing and swarming motility in Serratia liquefaciens MG1
Rasmussen, T. B., Manefield, M., Andersen, Jens Bo, Eberl, L., Anthoni, U., Christophersen, C., Steinberg, P., Kjelleberg, S. & Givskov, Michael, 2000, In: Microbiology. 146 Pt 12, p. 3237-44 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa
Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Heydorn, A., Mathee, K., Moser, Claus Ernst, Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146 ( Pt 10), p. 2481-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of N-acyl-homoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa
Wu, H., Song, Z., Hentzer, M., Andersen, J. B., Heydorn, A., Mathee, K., Moser, C., Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146, p. 2481-2493Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5838523
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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C-di-GMP regulates Pseudomonas aeruginosa stress response to tellurite during both planktonic and biofilm modes of growth
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Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes
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