Michael Givskov

Michael Givskov

Professor

Member of:


    1. 2013
    2. Published

      Identification of five structurally unrelated quorum-sensing inhibitors of Pseudomonas aeruginosa from a natural-derivative database

      Tan, S. Y. Y., Chua, S. L., Chen, Y., Rice, S. A., Kjelleberg, S., Nielsen, Thomas Eiland, Yang, L. & Givskov, Michael, Nov 2013, In: Antimicrobial Agents and Chemotherapy. 57, 11, p. 5629-5641 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Applying insights from biofilm biology to drug development - can a new approach be developed?

      Bjarnsholt, Thomas, Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Oct 2013, In: Nature Reviews. Drug Discovery. 12, 10, p. 791-808 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Clearance of Pseudomonas aeruginosa Foreign-Body Biofilm Infections through Reduction of the Cyclic Di-GMP Level in the Bacteria

      Hultqvist, Louise Dahl, van Gennip, M., Rybtke, Morten Levin, Wu, H., Chiang, W., Alhede, M., Høiby, Niels, Nielsen, T., Givskov, Michael & Tolker-Nielsen, Tim, Aug 2013, In: Infection and Immunity. 81, 8, p. 2705-13 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors

      Jakobsen, Tim Holm, Bjarnsholt, Thomas, Jensen, Peter Østrup, Givskov, Michael & Høiby, Niels, Jul 2013, In: Future Microbiology. 8, 7, p. 901-21 21 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Comparative transcriptomic analysis of the Burkholderia cepacia tyrosine kinase bceF mutant reveals a role in tolerance to stress, biofilm formation, and virulence

      Ferreira, A. A., Silva, I. I., Oliveira, V. V., Becker, J. J., Givskov, Michael, Ryan, R. R., Fernandes, F. & Moreira, L. M., May 2013, In: Applied and Environmental Microbiology. 79, 9, p. 3009-3020 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms

      Chiang, W., Nilsson, M., Jensen, Peter Østrup, Høiby, Niels, Nielsen, T., Givskov, Michael & Tolker-Nielsen, Tim, May 2013, In: Antimicrobial Agents and Chemotherapy. 57, 5, p. 2352-61 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Biofilm formation by Staphylococcus epidermidis on peritoneal dialysis catheters and the effects of extracellular products from Pseudomonas aeruginosa

      Pihl, M., Arvidsson, A., Skepö, M., Nilsson, M., Givskov, Michael, Tolker-Nielsen, Tim, Svensäter, G. & Davies, J. R., Apr 2013, In: Pathogens and Disease. 67, 3, p. 192-198 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation

      Dueholm, M. S., Søndergaard, M., Nilsson, M., Christiansen, G., Stensballe, A., Overgaard, M. T., Givskov, Michael, Tolker-Nielsen, Tim, Otzen, D. & Nielsen, P. H., 18 Mar 2013, In: MicrobiologyOpen. 2, p. 365-382 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      The exopolysaccharide gene cluster Bcam1330-Bcam1341 is involved in Burkholderia cenocepacia biofilm formation, and its expression is regulated by c-di-GMP and Bcam1349

      Fazli, M., McCarthy, Y., Givskov, Michael, Ryan, R. P. & Tolker-Nielsen, Tim, Feb 2013, In: MicrobiologyOpen. 2, 1, p. 105-122 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      C-di-GMP regulates antimicrobial peptide resistance in Pseudomonas aeruginosa

      Chua, S. L., Tan, S. Y., Rybtke, Morten Levin, Chen, Y., Rice, S. A., Kjelleberg, S., Tolker-Nielsen, Tim, Yang, L. & Givskov, Michael, 2013, In: Antimicrobial Agents and Chemotherapy. 57, 5, p. 2066-2075 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Comparative genomic analysis of rapid evolution of an extreme-drug- resistant Acinetobacter baumannii clone

      Tan, S., Chua, S. L., Liu, Y., Høiby, Niels, Andersen, L. P., Givskov, Michael, Song, Z. & Yang, L., 2013, In: Genome Biology and Evolution. p. 807–818

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes

      Jakobsen, T. H., Hansen, M. A., Jensen, P. Ø., Hansen, L., Riber, L., Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, K., Burmølle, M., Moser, C. E., Kühl, M., Ciofu, O., Givskov, M., Sørensen, S. J. & 2 others, Høiby, Niels & Bjarnsholt, Thomas, 2013, In: P L o S One. 8, 7, 17 p., e68484.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Engineering PQS biosynthesis pathway for enhancement of bioelectricity production in Pseudomonas aeruginosa microbial fuel cells

      Wang, V. B., Chua, S., Cao, B., Seviour, T., Nesatyy, V. J., Marsili, E., Kjelleberg, S., Givskov, Michael, Tolker-Nielsen, Tim, Song, H., Loo, J. S. C. & Yang, L., 2013, In: PLOS ONE. 8, 5, p. e63129 7 p., e63129.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      First case of E anophelis outbreak in an intensive-care unit

      Teo, J., Tan, S. Y. Y., Tay, M., Ding, Y., Kjelleberg, S., Givskov, Michael, Lin, R. T. P. & Yang, L., 2013, In: The Lancet. 382, 9895, p. 855-856 2 p.

      Research output: Contribution to journalComment/debateResearchpeer-review

    16. Published

      Identification of Burkholderia cenocepacia strain H111 virulence factors using nonmammalian infection hosts

      Schwager, S., Agnoli, K., Köthe, M., Feldmann, F., Givskov, Michael, Carlier, A. & Eberl, L., 2013, In: Infection and Immunity. 81, 1, p. 143-53 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Identification of LasR ligands through a virtual screening approach

      Skovstrup, S., Le Quement, S. T., Hansen, T., Jakobsen, Tim Holm, Harmsen, M., Tolker-Nielsen, Tim, Nielsen, T. E., Givskov, Michael & Taboureau, O., 2013, In: ChemMedChem. 8, 1, p. 157-63 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Kinetic Model for Signal Binding to the Quorum Sensing Regulator LasR

      Claussen, A., Jakobsen, Tim Holm, Bjarnsholt, Thomas, Givskov, Michael, Welch, M., Ferkinghoff-Borg, J. & Sams, T., 2013, In: International Journal of Molecular Sciences (Online). 14, 7, p. 13360-76 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Protoanemonin: a natural quorum sensing inhibitor that selectively activates iron starvation response

      Bobadilla Fazzini, R. A., Skindersoe, M. E., Bielecki, P., Puchalka, J., Givskov, Michael & Martins sos Santos, V. A. P., 2013, In: Environmental Microbiology Reports. 15, 1, p. 111-20 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Synthesis and biological evaluation of triazole-containing N-acyl homoserine lactones as quorum sensing modulators

      Stacy, D. M., Le Quement, S. T., Hansen, C., Clausen, J. W., Tolker-Nielsen, Tim, Brummond, J. W., Givskov, Michael, Nielsen, T. E. & Blackwell, H. E., 2013, In: Organic & Biomolecular Chemistry. 11, 6, p. 938-54 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. 2012
    22. Published

      Solid-phase synthesis of structurally diverse heterocycles by an amide-ketone condensation/N-acyliminium pictet-spengler sequence

      Komnatnyy, V. V., Givskov, Michael & Nielsen, T. E., Dec 2012, In: Chemistry. A European Journal. 18, 52, p. 16793-16800 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      The catabolite repression control protein Crc plays a role in the development of antimicrobial-tolerant subpopulations in Pseudomonas aeruginosa biofilms

      Zhang, L., Chiang, W., Gao, Q., Givskov, Michael, Tolker-Nielsen, Tim, Yang, L. & Zhang, G., Dec 2012, In: Microbiology. 158, 12, p. 3014-3019 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo

      van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Qvortrup, Klaus, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Combination of microscopic techniques reveals a comprehensive visual impression of biofilm structure and composition

      Alhede, M., Qvortrup, Klaus, Liebrechts, R., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 335-342 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Polysaccharides serve as scaffold of biofilms formed by mucoid Pseudomonas aeruginosa

      Yang, L., Hengzhuang, W., Wu, H., Damkiaer, S., Jochumsen, N., Song, Z., Givskov, Michael, Høiby, Niels & Molin, S., Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 366-376 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      The metabolically active subpopulation in Pseudomonas aeruginosa biofilms survives exposure to membrane-targeting antimicrobials via distinct molecular mechanisms

      Chiang, W., Pamp, S. J., Nilsson, Carl Martin Peter, Givskov, Michael & Tolker-Nielsen, Tim, Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 245-256 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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