Michael Givskov

Michael Givskov

Professor

Member of:


    1. 2011
    2. Published

      Effects of ginseng on Pseudomonas aeruginosa motility and biofilm formation

      Wu, H., Lee, B., Yang, L., Wang, H., Givskov, Michael, Molin, S., Høiby, Niels & Song, Z., 1 Jun 2011, In: F E M S Immunology and Medical Microbiology. 62, 1, p. 49-56 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      The contribution of cell-cell signaling and motility to bacterial biofilm formation

      Shrout, J. D., Tolker-Nielsen, Tim, Givskov, Michael & Parsek, M. R., May 2011, In: M R S Bulletin. 36, 5, p. 367-373 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Imaging N-acyl homoserine lactone quorum sensing in vivo

      Hultqvist, Louise Dahl, van Gennip, M., Jakobsen, Tim Holm, Givskov, Michael & Bjarnsholt, Thomas, 1 Jan 2011, In: Methods in Molecular Biology. 692, 2, p. 147-157 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Qualitative and quantitative determination of quorum sensing inhibition in vitro

      Jakobsen, Tim Holm, van Gennip, M., Hultqvist, Louise Dahl, Bjarnsholt, Thomas & Givskov, Michael, 1 Jan 2011, In: Methods in Molecular Biology. 692, 3, p. 253-263 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients

      Høiby, Niels, Johansen, Helle Krogh, Moser, Claus Ernst, Ciofu, Oana, Jensen, Peter Østrup, Kolpen, Mette, Mandsberg, L., Givskov, Michael, Molin, S. & Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer, p. 167-184 18 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    7. Published

      Influence of putative exopolysaccharide genes on Pseudomonas putida KT2440 biofilm stability

      Nilsson, M., Chiang, W., Fazli, M., Gjermansen, M., Givskov, Michael & Tolker-Nielsen, Tim, 2011, In: Environmental Microbiology. 13, 5, p. 1357-69

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Interfering with bacterial gossip.

      Bjarnsholt, Thomas, Tolker-Nielsen, Tim & Givskov, Michael, 2011, Biofilm perspectives: Biofilm highlight. Flemming, H-C., Wingender, J. & Szewzyk, U. (eds.). 1 ed. Berlin: Springer Publishing Company, p. 163-188 26 p. (Springer Series on Biofilms, Vol. 5).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    9. Published

      Phenotypes of Non-Attached Pseudomonas aeruginosa Aggregates Resemble Surface Attached Biofilm

      Alhede, M., Kragh, K. N., Qvortrup, Klaus, Allesen-Holm, M., van Gennip, M., Hultqvist, Louise Dahl, Jensen, Peter Østrup, Nielsen, A. K., Parsek, M., Wozniak, D., Molin, S., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 2011, In: P L o S One. 6, 11, p. e27943

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Quantitative analysis of the cellular inflammatory response against biofilm bacteria in chronic wounds

      Fazli, M., Bjarnsholt, Thomas, Kirketerp-Møller, K., Jørgensen, A., Andersen, C. B., Givskov, Michael & Tolker-Nielsen, Tim, 2011, In: Wound Repair and Regeneration. 19, 3, p. 387-91 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Quorum sensing in Aeromonas salmonicida subsp. achromogenes and the effect of the autoinducer synthase AsaI on bacterial virulence

      Schwenteit, J., Gram, L., Nielsen, K. F., Fridjonsson, O. H., Bornscheuer, U. T., Givskov, Michael & Gudmundsdottir, B. K., 2011, In: Veterinary Microbiology. 147, 3-4, p. 389-97

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Quorum sensing inhibitors disable bacterial biofilms.

      Bjarnsholt, Thomas, Tolker-Nielsen, Tim & Givskov, Michael, 2011, Emerging trends in in antibacterial discovery.. Miller, A. A. & Miller, P. F. (eds.). 1 ed. Norvich UK: HorizonBioscience, p. 211-224 14 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    13. Published

      The CRP/FNR family protein Bcam1349 is a c-di-GMP effector that regulates biofilm formation in the respiratory pathogen Burkholderia cenocepacia

      Fazli, M., O'Connell, A., Nilsson, M., Niehaus, K., Dow, J. M., Givskov, Michael, Ryan, R. P. & Tolker-Nielsen, Tim, 2011, In: Molecular Microbiology. 82, 2, p. 327-41

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      The clinical impact of bacterial biofilms

      Høiby, Niels, Ciofu, Oana, Johansen, Helle Krogh, Song, Z., Moser, Claus Ernst, Jensen, Peter Østrup, Molin, S., Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: International Journal of Oral Science. 3, 2, p. 55-65

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      The implication of Pseudomonas aeruginosa biofilms in infections

      Rybtke, Morten Levin, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: Inflammation & Allergy - Drug Targets. 10, 2, p. 141-57 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      True microbiota involved in chronic lung infection of cystic fibrosis patients found by culturing and 16S rRNA gene analysis

      Rudkjøbing, V. B., Thomsen, T. R., Alhede, M., Kragh, K. N., Nielsen, P. H., Johansen, U., Givskov, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2011, In: Journal of Clinical Microbiology. 49, 12, p. 4352-5 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. 2010
    18. Published

      Discovery of a quorum sensing modulator pharmacophore by 3D small-molecule microarray screening

      Marsden, D. M., Nicholson, R. L., Skindersoe, M. E., Galloway, W. R. J. D., Sore, H. F., Givskov, Michael, Salmond, G. P. C., Ladlow, M., Welch, M. & Spring, D. R., 7 Dec 2010, In: Organic & Biomolecular Chemistry. 8, 23, p. 5313-23 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Utility of in vivo transcription profiling for identifying Pseudomonas aeruginosa genes needed for gastrointestinal colonization and dissemination

      Koh, A. Y., Mikkelsen, P. J., Smith, R. S., Coggshall, K. T., Kamei, A., Givskov, Michael, Lory, S. & Pier, G. B., 1 Dec 2010, In: P L o S One. 5, 12, p. e15131

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Comparative microarray analysis reveals that the core biofilm-associated transcriptome of Pseudomonas aeruginosa comprises relatively few genes

      Patell, S., Gu, M., Davenport, P., Givskov, Michael, Waite, R. D. & Welch, M., Jun 2010, In: Environmental Microbiology Reports. 2, 3, p. 440-448 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis--a pilot randomized controlled trial

      Smyth, A. R., Cifelli, P. M., Ortori, C. A., Righetti, K., Lewis, S., Erskine, P., Holland, E. D., Givskov, Michael, Williams, P., Cámara, M., Barrett, D. A. & Knox, A., 1 Apr 2010, In: Pediatric Pulmonology. 45, 4, p. 356-62 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Quorum-sensing-regulated virulence factors in Pseudomonas aeruginosa are toxic to Lucilia sericata maggots

      Andersen, A. S., Joergensen, B., Bjarnsholt, Thomas, Johansen, H., Karlsmark, T., Givskov, Michael, Krogfelt, K. A., Andersen, A. S., Jørgensen, B., Bjarnsholt, T., Johansen, H., Karlsmark, Tonny, Givskov, M. & Krogfelt, K. A., 1 Feb 2010, In: Microbiology. 156, Pt 2, p. 400-7 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

      Kolpen, Mette, Hansen, C. R., Bjarnsholt, Thomas, Moser, C., Hultqvist, Louise Dahl, van Gennip, M., Ciofu, Oana, Mandsberg, L., Kharazmi, A., Döring, G., Givskov, Michael, Høiby, Niels & Jensen, Peter Østrup, 1 Jan 2010, In: Thorax. 65, 1, p. 57-62 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Jakobsen, Tim Holm, Phipps, R., Nielsen, A. K., Rybtke, Morten Levin, Tolker-Nielsen, Tim, Givskov, Michael, Høiby, Niels, Ciofu, Oana & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 1 Jan 2010, In: PLoS ONE. 5, 4, p. e10115

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Acetic acid and a buffer

      Bjarnsholt, Thomas, Givskov, Michael, P, H., Høiby, Niels, PO, J., HK, J. & K, K., 2010, Patent No. WO2009155931, 30 Jan 2010

      Research output: Patent

    26. Published

      An in vitro model of bacterial infections in wounds and other soft tissues

      Werthén, M., Henriksson, L., Jensen, Peter Østrup, Sternberg, C., Givskov, Michael & Bjarnsholt, Thomas, 2010, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 118, 2, p. 156-64 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Antibiotic resistance of bacterial biofilms

      Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael, Molin, S. & Ciofu, Oana, 2010, In: International Journal of Antimicrobial Agents. 35, 4, p. 322-332 11 p.

      Research output: Contribution to journalReviewResearchpeer-review

    28. Published

      Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

      Burmølle, Mette, Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.

      Research output: Contribution to journalReviewResearchpeer-review

    29. Published

      In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect

      Bjarnsholt, Thomas, van Gennip, M., Jakobsen, Tim Holm, Hultqvist, Louise Dahl, Jensen, Peter Østrup & Givskov, Michael, 2010, In: Nature Protocols (Print Edition). 5, 2, p. 282-93 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control

      Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 2010, In: Expert Reviews in Molecular Medicine. 12, p. e11 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Quorum sensing regulation in Aeromonas hydrophila

      Garde, C., Bjarnsholt, Thomas, Givskov, Michael, Jakobsen, Tim Holm, Hentzer, M., Claussen, A., Sneppen, K., Ferkinghoff-Borg, J. & Sams, T., 2010, In: Journal of Molecular Biology. 396, 4, p. 849-57 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      The bacteriology of chronic venous leg ulcer examined by culture-independent molecular methods

      Thomsen, T. R., Aasholm, M. S., Rudkjøbing, V. B., Saunders, A. M., Bjarnsholt, Thomas, Givskov, Michael, Kirketerp-Møller, K. & Nielsen, P. H., 2010, In: Wound Repair and Regeneration. 18, 1, p. 38-49 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      The immune system vs. Pseudomonas aeruginosa biofilms

      Jensen, Peter Østrup, Givskov, Michael, Bjarnsholt, Thomas & Moser, C., 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 292-305 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. 2009
    35. Published

      Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa

      van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, H. P., Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes

      Van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Phipps, R., Jensen, Peter Østrup, Christophersen, L., Pamp, S. J., Moser, C., Mikkelsen, P. J., Koh, A. Y., Tolker-Nielsen, Tim, Pier, G. B., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Jul 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 7, p. 537-46 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Fiandaca, M. J., Pedersen, J., Hansen, C. R., Andersen, C. B., Pressler, T., Givskov, Michael & Høiby, Niels, 1 Jun 2009, In: Pediatric Pulmonology. 44, 6, p. 547-58 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis

      Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes

      Alhede, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Phipps, R. K., Moser, Claus Ernst, Christophersen, L., Hultqvist, Louise Dahl, van Gennip, M., Parsek, M., Høiby, Niels, Rasmussen, T. B. & Givskov, Michael, 2009, In: Microbiology. 155, 11, p. 3500-3508 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Biofilms and type III secretion are not mutually exclusive in Pseudomonas aeruginosa

      Mikkelsen, H., Bond, N. J., Skindersoe, M. E., Givskov, Michael, Lilley, K. S. & Welch, M., 2009, In: Microbiology. 155, Pt 3, p. 687-98 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Computer-aided identification of recognized drugs as Pseudomonas aeruginosa quorum-sensing inhibitors

      Yang, L., Rybtke, Morten Levin, Jakobsen, Tim Holm, Hentzer, M., Bjarnsholt, Thomas, Givskov, Michael & Tolker-Nielsen, Tim, 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2432-43 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Detection of Bacteria by Fluorescence in Situ Hybridization in Culture-Negative Soft Tissue Filler Lesions

      Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Givskov, Michael, Janssen, M. & Christensen, L. H., 2009, In: Dermatologic Surgery. 35 Suppl 2, p. 1620-1624 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Nonrandom distribution of Pseudomonas aeruginosa and Staphylococcus aureus in chronic wounds

      Fazli, M., Bjarnsholt, Thomas, Kirketerp-Møller, K., Jørgensen, B., Andersen, A. S., Krogfelt, K. A., Givskov, Michael & Tolker-Nielsen, Tim, 2009, In: Journal of Clinical Microbiology. 47, 12, p. 4084-9 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Novel experimental Pseudomonas aeruginosa infection model mimicking long-term host-pathogen interactions in cystic fibrosis.

      Moser, Claus Ernst, van Gennip, M., Bjarnsholt, Thomas, Jensen, P. Ø., Lee, B., Hougen, H. P., Calum, Henrik Pierre, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, p. 95-107 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Pseudomonas aeruginosa quorum-sensing signal molecules interfere with dendritic cell-induced T-cell proliferation

      Skindersoe, M. E., Zeuthen, L. H., Brix, Susanne, Fink, L. N., Lazenby, J., Whittall, C., Williams, P., Diggle, S. P., Frøkiær, Hanne, Cooley, M. & Givskov, Michael, 2009, In: FEMS Immunology and Medical Microbiology. 55, 3, p. 335-45 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Pyoverdine and PQS mediated subpopulation interactions involved in Pseudomonas aeruginosa biofilm formation

      Yang, L., Nilsson, Carl Martin Peter, Gjermansen, M., Givskov, Michael & Tolker-Nielsen, Tim, 2009, In: Molecular Microbiology. 74, 6, p. 1380-92 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. 2008
    48. Published

      Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa

      Skindersoe, M. E., Alhede, M., Phipps, R., Yang, L., Jensen, P. O., Rasmussen, T. B., Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 1 Oct 2008, In: Antimicrobial Agents and Chemotherapy. 52, 10, p. 3648-63 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Distribution, organization, and ecology of bacteria in chronic wounds

      Kirketerp-Møller, K., Jensen, Peter Østrup, Fazli, M., Madsen, K. G., Pedersen, J., Moser, C., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Aug 2008, In: Journal of Clinical Microbiology. 46, 8, p. 2717-22 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Pseudomonas aeruginosa uses type III secretion system to kill biofilm-associated amoebae

      Matz, C., Moreno, A. M., Alhede, M., Manefield, M., Hauser, A. R., Givskov, Michael & Kjelleberg, S., 2008, In: ISME Journal. 2, 8, p. 843-852 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Detection and inhibition of bacterial cell-cell communication

      Rice, S. A., McDougald, D., Givskov, Michael & Kjelleberg, S., 2008, In: Methods in Molecular Biology. 431, p. 55-68 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Quorum sensing inhibitory drugs as next generation antimicrobials: worth the effort?

      Bjarnsholt, Thomas & Givskov, Michael, 2008, In: Current Infectious Disease Reports. 10, 1, p. 22-28 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Role of quorum sensing by Pseudomonas aeruginosa in microbial keratitis and cystic fibrosis

      Willcox, M. D. P., Zhu, H., Conibear, T. C. R., Hume, E. B. H., Givskov, Michael, Kjelleberg, S. & Rice, S. A., 2008, In: Microbiology. 154, Pt 8, p. 2184-94 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilms

      Barken, K. B., Pamp, S. J., Yang, L., Gjermansen, M., Bertrand, J. J., Klausen, M., Givskov, Michael, Whitchurch, C. B., Engel, J. N. & Tolker-Nielsen, Tim, 2008, In: Environmental Microbiology. 10, 9, p. 2331-2343 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 5838523