Michael Givskov

Michael Givskov

Professor

Member of:


    1. 2004
    2. Published

      Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice

      Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Molin, S., Givskov, Michael & Høiby, Niels, 2004, In: Journal of Antimicrobial Chemotherapy. 53, 6, p. 1054-61 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. 2003
    4. Published

      Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors

      Hentzer, M., Wu, H., Andersen, Jens Bo, Riedel, K., Rasmussen, T. B., Bagge, N., Kumar, N., Schembri, M. A., Song, Z., Kristoffersen, P., Manefield, M., Costerton, J. W., Molin, S., Eberl, L., Steinberg, P., Kjelleberg, S., Høiby, Niels & Givskov, Michael, 2003, In: EMBO Journal. 22, 15, p. 3803-15 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Bacterial biofilms: prokaryotic adventures in multicellularity

      Webb, J. S., Givskov, Michael & Kjelleberg, S., 2003, In: Current Opinion in Microbiology. 6, 6, p. 578-85 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Cell death in Pseudomonas aeruginosa biofilm development

      Webb, J. S., Thompson, L. S., James, S., Charlton, T., Tolker-Nielsen, T., Koch, B., Givskov, Michael & Kjelleberg, S., 2003, In: Journal of Bacteriology. 185, 15, p. 4585-92 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Identification and characterization of a GDSL esterase gene located proximal to the swr quorum-sensing system of Serratia liquefaciens MG1

      Riedel, K., Talker-Huiber, D., Givskov, Michael, Schwab, H. & Eberl, L., 2003, In: Applied and Environmental Microbiology. 69, 7, p. 3901-10 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics

      Arevalo-Ferro, C., Hentzer, M., Reil, G., Görg, A., Kjelleberg, S., Givskov, Michael, Riedel, K. & Eberl, L., 2003, In: Environmental Microbiology. 5, 12, p. 1350-69 19 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Influence of food preservation parameters and associated microbiota on production rate, profile and stability of acylated homoserine lactones from food-derived Enterobacteriaceae

      Ravn Flodgaard, L., Christensen, A. B., Molin, S., Givskov, Michael & Gram, L., 2003, In: International Journal of Food Microbiology. 84, 2, p. 145-56 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections

      Hentzer, M. & Givskov, Michael, 2003, In: Journal of Clinical Investigation. 112, 9, p. 1300-7 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Quorum sensing : a novel target for the treatment of biofilm infections

      Hentzer, M., Eberl, L., Nielsen, J. & Givskov, Michael, 2003, In: BioDrugs. 17, 4, p. 241-50 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Quorum-sensing-directed protein expression in Serratia proteamaculans B5a

      Christensen, A. B., Riedel, K., Eberl, L., Flodgaard, L. R., Molin, S., Gram, L. & Givskov, Michael, 2003, In: Microbiology. 149, Pt 2, p. 471-83 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Surface motility in Pseudomonas sp. DSS73 is required for efficient biological containment of the root-pathogenic microfungi Rhizoctonia solani and Pythium ultimum

      Andersen, Jens Bo, Koch, B., Nielsen, T. H., Sørensen, D., Hansen, M., Nybroe, O., Christophersen, C., Sørensen, J., Molin, S. & Givskov, Michael, 2003, In: Microbiology. 149, Pt 1, p. 37-46 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Synthesis of furanone-based natural product analogues with quorum sensing antagonist activity

      Hjelmgaard, T., Persson, T., Rasmussen, T. B., Givskov, Michael & Nielsen, J., 2003, In: Bioorganic & Medicinal Chemistry. 11, 15, p. 3261-71 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. 2002
    16. Published

      Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers

      Olsen, J. A., Severinsen, R., Rasmussen, T. B., Hentzer, M., Givskov, Michael, Nielsen, J. & Nielsen, J., 11 Feb 2002, In: Bioorganic and Medicinal Chemistry Letters. 12, 3, p. 325-328 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. An attractive surface: gram-negative bacterial biofilms

      Schembri, M., Givskov, Michael & Klemm, P., 2002, In: Science Signaling. 2002, 132, p. re6

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Antibiotic and biosurfactant properties of cyclic lipopeptides produced by fluorescent Pseudomonas spp. from the sugar beet rhizosphere

      Nielsen, T. H., Sørensen, D., Tobiasen, C., Andersen, Jens Bo, Christophersen, C., Givskov, Michael & Sørensen, J., 2002, In: Applied and Environmental Microbiology. 68, 7, p. 3416-23 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD.

      Bagge, N., Ciofu, Oana, Hentzer, M., Campbell, J. I. A., Givskov, Michael & Høiby, Niels, 2002, In: Antimicrobial Agents and Chemotherapy. 46, 11, p. 3406-11 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Food spoilage--interactions between food spoilage bacteria

      Gram, L., Ravn, L., Rasch, M., Bruhn, J. B., Christensen, A. B. & Givskov, Michael, 2002, In: International Journal of Food Microbiology. 78, 1-2, p. 79-97 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Genetic analysis of functions involved in the late stages of biofilm development in Burkholderia cepacia H111

      Huber, B., Riedel, K., Köthe, M., Givskov, Michael, Molin, S. & Eberl, L., 2002, In: Molecular Microbiology. 46, 2, p. 411-26 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover

      Manefield, M., Rasmussen, T. B., Henzter, M., Andersen, Jens Bo, Steinberg, P., Kjelleberg, S. & Givskov, Michael, 2002, In: Microbiology. 148, Pt 4, p. 1119-27 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Identification and characterization of an N-acylhomoserine lactone-dependent quorum-sensing system in Pseudomonas putida strain IsoF

      Steidle, A., Allesen-Holm, M., Riedel, K., Berg, G., Givskov, Michael, Molin, S. & Eberl, L., 2002, In: Applied and Environmental Microbiology. 68, 12, p. 6371-82 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound

      Hentzer, M., Riedel, K., Rasmussen, T. B., Heydorn, A., Andersen, Jens Bo, Parsek, M. R., Rice, S. A., Eberl, L., Molin, S., Høiby, Niels, Kjelleberg, S. & Givskov, Michael, 2002, In: Microbiology. 148, Pt 1, p. 87-102 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Lipopeptide production in Pseudomonas sp. strain DSS73 is regulated by components of sugar beet seed exudate via the Gac two-component regulatory system

      Koch, B., Nielsen, T. H., Sørensen, D., Andersen, J. B., Christophersen, C., Molin, S., Givskov, Michael, Sørensen, J. & Nybroe, O., 2002, In: Applied and Environmental Microbiology. 68, 9, p. 4509-16 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Lysophosphatidic acid inhibition of the accumulation of Pseudomonas aeruginosa PAO1 alginate, pyoverdin, elastase and LasA

      Laux, D. C., Corson, J. M., Givskov, Michael, Hentzer, M., Møller, A., Wosencroft, K. A., Olson, J. C., Krogfelt, K. A., Goldberg, J. B. & Cohen, P., 2002, In: Microbiology. 148, Pt 6, p. 1709-23 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Quantitative effects of medium hardness and nutrient availability on the swarming motility of Serratia liquefaciens

      Bees, M. A., Andresén, P., Mosekilde, E. & Givskov, Michael, 2002, In: Bulletin of Mathematical Biology. 64, 3, p. 565-87 22 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers

      Olsen, J. A., Severinsen, R. E., Rasmussen, T. B., Hentzer, M., Givskov, Michael & Nielsen, J., 2002, In: Bioorganic & Medicinal Chemistry Letters. 12, 3, p. 325-8 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Targeting quorum sensing for treatment of chronic bacterial biofilm infections

      Hentzer, M., Givskov, Michael & Parsek, M. R., 2002, In: Laboratory Medicine. 33, 4, p. 295-306 12 p.

      Research output: Contribution to journalReviewResearchpeer-review

    30. The identification of a tetracycline resistance gene tet(M), on a Tn916-like transposon, in the Bacillus cereus group

      Agersø, Y., Jensen, L. B., Givskov, Michael & Roberts, M. C., 2002, In: FEMS Microbiology Letters. 214, 2, p. 251-6 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. 2001
    32. Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function

      Hentzer, M., Teitzel, G. M., Balzer, G. J., Heydorn, A., Molin, S., Givskov, Michael & Parsek, M. R., 2001, In: Journal of Bacteriology. 183, 18, p. 5395-401 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Genetic and chemical tools for investigating signaling processes in biofilms

      Charlton, T., Givskov, Michael, deNys, R., Andersen, Jens Bo, Hentzer, M., Rice, S. & Kjelleberg, S., 2001, In: Methods in Enzymology. 336, p. 108-28 21 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Halogenated furanones from the red alga, Delisea pulchra, inhibit carbapenem antibiotic synthesis and exoenzyme virulence factor production in the phytopathogen Erwinia carotovora

      Manefield, M., Welch, M., Givskov, Michael, Salmond, G. P. & Kjelleberg, S., 2001, In: F E M S Microbiology Letters. 205, 1, p. 131-8 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Methods for detecting acylated homoserine lactones produced by Gram-negative bacteria and their application in studies of AHL-production kinetics

      Ravn, L., Christensen, A. B., Molin, S., Givskov, Michael & Gram, L., 2001, In: Journal of Microbiological Methods. 44, 3, p. 239-51 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      N-acyl homoserinelactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms

      Riedel, K., Mentzer, M., Geisenberger, O., Huber, B., Steidle, A., Wu, H., Høiby, Niels, Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, p. 3249-3262

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. N-acyl-L-homoserine lactone-mediated regulation of the lip secretion system in Serratia liquefaciens MG1

      Riedel, K., Ohnesorg, T., Krogfelt, K. A., Hansen, T. S., Omori, K., Givskov, Michael & Eberl, L., 2001, In: Journal of Bacteriology. 183, 5, p. 1805-9 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms

      Riedel, K., Hentzer, M., Geisenberger, O., Huber, B., Steidle, A., Wu, H., Høiby, Niels, Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, Pt 12, p. 3249-62 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Pseudomonas aeruginosa mutations in lasI and rhlI quorum sensing systems result in milder chronic lung infection

      Wu, H., Song, Z., Givskov, Michael, Doring, G., Worlitzsch, D., Mathee, K., Rygaard, J. & Høiby, Niels, 2001, In: Microbiology. 147, Pt 5, p. 1105-1113 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility

      Huber, B., Riedel, K., Hentzer, M., Heydorn, A., Gotschlich, A., Givskov, Michael, Molin, S. & Eberl, L., 2001, In: Microbiology. 147, Pt 9, p. 2517-28 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Visualization of N-acylhomoserine lactone-mediated cell-cell communication between bacteria colonizing the tomato rhizosphere

      Steidle, A., Sigl, K., Schuhegger, R., Ihring, A., Schmid, M., Gantner, S., Stoffels, M., Riedel, K., Givskov, Michael, Hartmann, A., Langebartels, C. & Eberl, L., 2001, In: Applied and Environmental Microbiology. 67, 12, p. 5761-70 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. gfp-based N-acyl homoserine-lactone sensor systems for detection of bacterial communication

      Andersen, J. B., Heydorn, A., Hentzer, M., Eberl, L., Geisenberger, O., Christensen, B. B., Molin, S. & Givskov, Michael, 2001, In: Applied and Environmental Microbiology. 67, 2, p. 575-85 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. 2000
    44. A novel and sensitive method for the quantification of N-3-oxoacyl homoserine lactones using gas chromatography-mass spectrometry: application to a model bacterial biofilm

      Charlton, T. S., de Nys, R., Netting, A., Kumar, N., Hentzer, M., Givskov, Michael & Kjelleberg, S., 2000, In: Environmental Microbiology. 2, 5, p. 530-41 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Communication systems as targets for biological control

      Kjelleberg, S. & Givskov, Michael, 2000, 1 ed. 1 p. (Environmental Microbiology).

      Research output: Book/ReportBookResearch

    46. Published

      Detection of N-acyl-homoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa

      Wu, H., Song, Z., Hentzer, M., Andersen, J. B., Heydorn, A., Mathee, K., Moser, C., Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146, p. 2481-2493

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa

      Wu, H., Song, Z., Hentzer, M., Andersen, Jens Bo, Heydorn, A., Mathee, K., Moser, Claus Ernst, Eberl, L., Molin, S., Høiby, Niels & Givskov, Michael, 2000, In: Microbiology. 146 ( Pt 10), p. 2481-93 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Experimental reproducibility in flow-chamber biofilms

      Heydorn, A., Ersbøll, B. K., Hentzer, M., Parsek, M. R., Givskov, Michael & Molin, S., 2000, In: Microbiology. 146 ( Pt 10), p. 2409-15 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      How Delisea pulchra furanones affect quorum sensing and swarming motility in Serratia liquefaciens MG1

      Rasmussen, T. B., Manefield, M., Andersen, Jens Bo, Eberl, L., Anthoni, U., Christophersen, C., Steinberg, P., Kjelleberg, S. & Givskov, Michael, 2000, In: Microbiology. 146 Pt 12, p. 3237-44 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Inactivation of gltB abolishes expression of the assimilatory nitrate reductase gene (nasB) in Pseudomonas putida KT2442

      Eberl, L., Ammendola, A., Rothballer, M. H., Givskov, Michael, Sternberg, C., Kilstrup, M., Schleifer, K. H. & Molin, S., 2000, In: Journal of Bacteriology. 182, 12, p. 3368-76 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis

      Geisenberger, O., Givskov, Michael, Riedel, K., Høiby, Niels, Tümmler, B. & Eberl, L., 2000, In: F E M S Microbiology Letters. 184, 2, p. 273-8 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Production of N-acyl-L-homoserine lactones by Pseudomonas aeruginosa isolates from chronic lung infections associated with cystic fibrosis

      Geisenberger, O., Givskov, Michael, Riedel, K., Høiby, Niels, Tümmler, B. & Eberl, L., 2000, In: FEMS Microbiology Letters. 184, p. 273-278

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Quantification of biofilm structures by the novel computer program COMSTAT

      Heydorn, A., Nielsen, A. T., Hentzer, M., Sternberg, C., Givskov, Michael, Ersbøll, B. K. & Molin, S., 2000, In: Microbiology. 146 ( Pt 10), p. 2395-407 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. The interaction of thin-film flow, bacterial swarming and cell differentiation in colonies of Serratia liquefaciens

      Bees, M. A., Andresén, P., Mosekilde, E. & Givskov, Michael, 2000, In: Journal of Mathematical Biology. 40, 1, p. 27-63 37 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. rpoS gene function is a disadvantage for Escherichia coli BJ4 during competitive colonization of the mouse large intestine

      Krogfelt, K. A., Hjulgaard, M., Sørensen, K., Cohen, P. & Givskov, Michael, 2000, In: Infection and Immunity. 68, 5, p. 2518-24 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 5838523