Niels Høiby

Niels Høiby

Professor, No job title

Member of:


    1. 2010
    2. Published

      Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

      Kolpen, Mette, Hansen, C. R., Bjarnsholt, Thomas, Moser, C., Hultqvist, Louise Dahl, van Gennip, M., Ciofu, Oana, Mandsberg, L., Kharazmi, A., Döring, G., Givskov, Michael, Høiby, Niels & Jensen, Peter Østrup, 1 Jan 2010, In: Thorax. 65, 1, p. 57-62 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Mutator P. aeruginosa with Impaired Oxidative Repair System (mutT) forms thicker biofilms with increased tolerance to antibiotics compared to PAO1

      Mandsberg, L. F., Sternberg, C., Molin, S., Poulsen, Henrik Enghusen, Høiby, Niels & Ciofu, O., 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    4. Published

      Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients

      Nørskov-Lauritsen, N., Johansen, Helle Krogh, Fenger, M. G., Nielsen, X. C., Pressler, T., Olesen, H. V. & Høiby, Niels, 1 Aug 2010, In: Journal of Clinical Microbiology. 48, 8, p. 2981-3 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      IMPACT OF EARLY AGGRESSIVE ANTIBIOTIC ERADICATION THERAPY FOR RESPIRATORY

      Pressler, T., Nielsen, K. G. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    6. Published

      Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts

      Rau, M. H., Hansen, S. K., Johansen, Helle Krogh, Thomsen, L. E., Workman, C. T., Nielsen, K. F., Jelsbak, L., Høiby, Niels, Yang, L. & Molin, S., 1 Jun 2010, In: Environmental Microbiology. 12, 6, p. 1643-58 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Detection of microorganisms involved in airway infection of cystic fibrosis patients by standard culturing 6 molecular methods

      Rudkjøbing, V., Thomsen, T. R., Nielsen, P. H., Alhede, M., Johansen, U. R., Høiby, Niels & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    8. Published

      Panax ginseng has anti-infective activity against opportunistic pathogen Pseudomonas aeruginosa by inhibiting quorum sensing, a bacterial communication process critical for establishing infection

      Song, Z., Kong, K. F., Wu, H., Maricic, N., Ramalingam, B., Priestap, H., Schneper, L., Quirke, J. M. E., Høiby, Niels & Mathee, K., 1 Nov 2010, In: Phytomedicine. 17, 13, p. 1040-6 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Acetic acid and a buffer

      Bjarnsholt, Thomas, Givskov, Michael, P, H., Høiby, Niels, PO, J., HK, J. & K, K., 2010, Patent No. WO2009155931, 30 Jan 2010

      Research output: Patent

    10. Published

      Relative contribution of Prevotella intermedia and Pseudomonas aeruginosa to lung pathology in airways of patients with cystic fibrosis

      Ulrich, M., Beer, I., Braitmaier, P., Dierkes, M., Kummer, F., Krismer, B., Schumacher, U., Gräpler-Mainka, U., Riethmüller, J., Jensen, Peter Østrup, Bjarnsholt, Thomas, Høiby, Niels, Bellon, G. & Döring, G., 1 Nov 2010, In: Thorax. 65, 11, p. 978-984 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Ciprofloxacin shows concentration-dependent killing of P. aeruginosa biofilm in vitro

      Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    12. Published

      Colistin shows concentration-dependent killing of Pseudomonas aeruginosa biofilm in vitro

      Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    13. Published

      Imipenem shows time dependent killing of P aeruginosa PAO1 biofilm in vitro and in vivo

      Wang, H., Wu, H., Song, Z. & Høiby, Niels, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    14. Published

      Ginseng affects motilities of Pseudomonas aeruginosa

      Wu, H., Lee, B. L. R., Yang, L., Givskov, M. C., Molin, S., Høiby, Niels & Song, Z., 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    15. Published

      Lipocalin 2 is protective against E. coli pneumonia

      Wu, H., Santoni-Rugiu, E., Ralfkiaer, E., Porse, Bo Torben, Moser, Claus Ernst, Høiby, Niels, Borregaard, N. & Cowland, J. B., 2010, In: Respiratory research. 11, p. 96

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Lipocalin 2 is protective against E. coli pneumonia

      Wu, H., Santoni Rugiu, Eric, Ralfkiaer, E., Porse, Bo Torben, Moser, C., Høiby, Niels, Borregaard, N., Cowland, J. B., Wu, H., Santoni Rugiu, Eric, Ralfkiær, E., Porse, B. T., Moser, C. E., Høiby, N., Borregaard, N. & Cowland, J., 15 Jun 2010, In: Respiratory research (Online). 11, 96, 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Visualization of in vivo biofilm developing on silicone implants and the interaction with the cellular response

      van Gennip, M., Christensen, L., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    18. Published

      Visualization of the in vivo interaction of a P. aeruginosa biofilm & the innate host cellular response

      van Gennip, M., Christensen, L. D., Qvortrup, K., Alhede, M., Jensen, Peter Østrup, Høiby, Niels, Givskov, M. & Bjarnsholt, Thomas, 2010. 0 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    19. 2009
    20. Published

      Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes

      Alhede, M., Bjarnsholt, Thomas, Jensen, Peter Østrup, Phipps, R. K., Moser, Claus Ernst, Christophersen, L., Hultqvist, Louise Dahl, van Gennip, M., Parsek, M., Høiby, Niels, Rasmussen, T. B. & Givskov, Michael, 2009, In: Microbiology. 155, 11, p. 3500-3508 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients

      Bjarnsholt, Thomas, Jensen, Peter Østrup, Fiandaca, M. J., Pedersen, J., Hansen, C. R., Andersen, C. B., Pressler, T., Givskov, Michael & Høiby, Niels, 1 Jun 2009, In: Pediatric Pulmonology. 44, 6, p. 547-58 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Influence of antidrug antibodies on plectasin efficacy and pharmacokinetics

      Brinch, K. S., Frimodt-Møller, N., Høiby, Niels & Kristensen, H., 2009, In: Antimicrobial Agents and Chemotherapy. 53, 11, p. 4794-800 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Plectasin shows intracellular activity against Staphylococcus aureus in human THP-1 monocytes and in a mouse peritonitis model

      Brinch, K. S., Sandberg, A., Baudoux, P., Van Bambeke, F., Tulkens, P. M., Frimodt-Møller, N., Høiby, Niels & Kristensen, H., 2009, In: Antimicrobial Agents and Chemotherapy. 53, 11, p. 4801-8 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Hjertesygdomme

      Haunsø, S., Boesgaard, S., Bundsgaard, H., Bøtker, H. E., Carlsen, J., Clemmensen, P., Egeblad, H., Engstrøm, T., Grande, P., Hansen, H. S., Hassager, C., Høiby, N., Høilund-Carlsen, P. F., Kjeldsen, K., Køber, L., Larsen, M. L., Nordestgaard, B., Pedersen, A. K., Sigurd, B., Svendsen, J. H. & 2 others, Søndergaard, Lars & Sørensen, K., 2009, Medicinsk Kompendium. Schaffalitzky de Muckadell, O. B., Haunsø, S. & Vilstrup, H. (eds.). 17 ed. København: Nyt Nordisk Forlag Arnold Busck, p. 908-1216 309 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    25. Published

      Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: A European consensus

      Heijerman, H., Westerman, E., Conway, S., Touw, D., Döring, G., Høiby, Niels & consensus working group, C. W. G., 2009, In: Journal of Cystic Fibrosis. 8, 5, p. 295-315 20 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Klinisk mikrobiologi og infektionsmedicin - almen del

      Høiby, Niels & Skinhøj, P., 2009, København: FADL's Forlag. 114 p.

      Research output: Book/ReportBookResearchpeer-review

    27. Published

      Chromosomal mechanisms of aminoglycoside resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients

      Islam, S., Oh, H., Jalal, S., Karpati, F., Ciofu, Oana, Høiby, Niels & Wretlind, B., 2009, In: Clinical Microbiology and Infection. 15, 1, p. 60-6 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Infektiøs endokardit

      Kjeldsen, K., Høiby, Niels, Egeblad, H., Muckadell, O. B. S. D., Haunsoe, S. & Vilstrup, H., 2009, Medicinsk Kompendium. 17th ed. København: Dansk Sygeplejeråd, p. 1047-1057 10 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    29. Published

      Differences in prevalence and treatment of Pseudomonas aeruginosa in cystic fibrosis centres in Denmark, Norway and Sweden

      Knudsen, P. K., Olesen, H. V., Høiby, Niels, Johannesson, M., Karpati, F., Laerum, B. N., Meyer, P., Pressler, T., Lindblad, A. & Scandinavian CF Study Consortium (SCFSC), S. C. S. C. (., 2009, In: Journal of Cystic Fibrosis. 8, 2, p. 135-42 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system

      Mandsberg, L. F., Ciofu, Oana, Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen, Høiby, Niels, Mandsberg, L. F., Ciofu, O., Kirkby, N., Christiansen, L. E., Poulsen, Henrik Enghusen & Høiby, N., 1 Jun 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2483-91 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis

      Moser, C., Gennip, M. V., Bjarnsholt, Thomas, Jensen, Peter Østrup, Lee, B., Hougen, H. P., Calum, H., Ciofu, Oana, Givskov, Michael, Molin, S. & Høiby, Niels, 1 Feb 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 2, p. 95-107 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Novel experimental Pseudomonas aeruginosa infection model mimicking long-term host-pathogen interactions in cystic fibrosis.

      Moser, Claus Ernst, van Gennip, M., Bjarnsholt, Thomas, Jensen, P. Ø., Lee, B., Hougen, H. P., Calum, Henrik Pierre, Ciofu, Oana, Givskov, Michael & Høiby, Niels, 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, p. 95-107 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Extracellular DNA and F-actin as targets in antibiofilm cystic fibrosis therapy

      Tolker-Nielsen, Tim & Høiby, Niels, 2009, In: Future Microbiology. 4, p. 645-7 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes

      Van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Phipps, R., Jensen, Peter Østrup, Christophersen, L., Pamp, S. J., Moser, C., Mikkelsen, P. J., Koh, A. Y., Tolker-Nielsen, Tim, Pier, G. B., Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Jul 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 7, p. 537-46 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice

      de Vrankrijker, A. M. M., Wolfs, T. F. W., Ciofu, Oana, Høiby, Niels, van der Ent, C. K., Poulsen, Steen Seier & Johansen, Helle Krogh, 2009, In: Journal of Medical Virology. 81, 12, p. 2096-103 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa

      van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, H. P., Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. 2008
    38. Published

      Why chronic wounds will not heal: a novel hypothesis

      Bjarnsholt, Thomas, Kirketerp-Møller, K., Jensen, Peter Østrup, Madsen, K. G., Phipps, R. K., Krogfelt, K., Høiby, Niels & Givskov, Michael, 2008, In: Wound Repair and Regeneration. 16, 1, p. 2-10 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection

      Bohn, Y. T., Brandes, G., Rakhimova, E., Horatzek, S., Salunkhe, P., Munder, A., van Barneveld, A., Jordan, D., Bredenbruch, F., Häussler, S., Riedel, K., Eberl, L., Jensen, Peter Østrup, Bjarnsholt, Thomas, Moser, C., Høiby, Niels, Tümmler, B. & Wiehlmann, L., 2008, In: Molecular Microbiology. 71, 3, p. 730-47 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Thermal injury induces impaired function in polymorphonuclear neutrophil granulocytes and reduced control of burn wound infection

      Calum, Henrik Pierre, Moser, Claus Ernst, Jensen, Peter Østrup, Christoffersen, L., Damlund, D. S. M., Alhede, M., Bjarnsholt, Thomas, Hougen, H. P., Givskov, Michael, Jacobsen, G. K. & Høiby, Niels, 2008, In: Clinical and Experimental Immunology. 156, 1, p. 102-110 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Investigation of the algT operon sequence in mucoid and non-mucoid Pseudomonas aeruginosa isolates from 115 Scandinavian patients with cystic fibrosis and in 88 in vitro non-mucoid revertants.

      Ciofu, Oana, Lee, B., Johannesson, M., Hermansen, N. O., Meyer, P., Høiby, Niels & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 2008, In: Microbiology. 154, Pt 1, p. 103-13 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Early aggressive eradication therapy for intermittent Pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience

      Hansen, C. R., Pressler, T. & Høiby, Niels, 2008, In: Journal of Cystic Fibrosis. 7, 6, p. 523-530 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Long-term, low-dose azithromycin treatment reduces the incidence but increases macrolide resistance in Staphylococcus aureus in Danish CF patients

      Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, H. K., 2008, In: Journal of Cystic Fibrosis. 8, 1, p. 58-62 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Den 2. kittelrevolution?

      Høiby, Niels, Johansen, Helle Krogh, Tvede, M. & Andersen, Leif Percival, 2008, In: Ugeskrift for læger. 170, 14, p. 1169

      Research output: Contribution to journalComment/debateResearch

    45. Published

      125 years anniversary of Christian Gram's staining method

      Høiby, Niels, 2008, In: ESCMID NEWS. 2, p. 49-51 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      A master of adaptation and survival strategies

      Høiby, Niels, Johansen, H. K., Moser, C., Ciofu, Oana & Rehm, B. H. A., 2008, Pseudomonas. Model Organism, Pathogen, Cell Factory. Weinheim: Wiley-VCH, Vol. 2. p. 25-44 19 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    47. Published

      Generel bakteriologi

      Høiby, Niels, Ciofu, Oana, Johansen, H. K., Andersen, L. P. & Skinhøj, P., 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 4. p. 21-107 86 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    48. Published

      Klinisk Mikrobiologi og Infektionsmedicin

      Høiby, Niels & Skinhøj, P., 2008, København: FADL's Forlag. 563 p.

      Research output: Book/ReportBookResearchpeer-review

    49. Published

      Korte træk af mikrobiologiens historie

      Høiby, Niels & Skinhøj, P., 2008, Klinisk Mikrobiologi og Infektionsmedicin. København: FADL's Forlag, Vol. 1. p. 1-4 3 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    50. Published

      Mikrobiologi - alment

      Høiby, Niels, Høiby, Niels (ed.) & Skinhøj, P. (ed.), 2008, Klinisk Mikrobiologi og Infektionsmedicin. København: FADL's Forlag, Vol. 3rd. p. 5-8 4 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    51. Published

      Systematisk bakteriologi

      Høiby, Niels & Skinhøj, P., 2008, Klinisk Mikrobiologi og Infektionsmedicin. København: FADL's Forlag, Vol. 5. p. 109-222 113 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    52. Published

      Klinisk bakteriologi, infektionshygiejne og antibiotikabehandling

      Johansen, H. K., Andersen, L. P., Skinhoj, P., Høiby, Niels & Johansen, Helle Krogh, 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 6. p. 223-298 75 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

    53. Published

      [Has the new technology made Gram's staining method redundant? The Danish Society of Clinical Microbiology]

      Johansen, H. K., Bjarnsholt, T. & Høiby, Niels, 2008, In: Ugeskrift for læger. 170, 12, p. 1041-

      Research output: Contribution to journalJournal articleResearchpeer-review

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