Niels Høiby

Niels Høiby

Professor, No job title

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    ORCID: 0000-0002-1347-725X

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    1. Published

      Applying insights from biofilm biology to drug development - can a new approach be developed?

      Bjarnsholt, Thomas, Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Oct 2013, In: Nature Reviews. Drug Discovery. 12, 10, p. 791-808 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis

      Garred, P., Pressler, T., Madsen, H. O., Frederiksen, B., Svejgaard, A., Høiby, Niels, Schwartz, M. & Koch, C., 1999, In: Journal of Clinical Investigation. 104, p. 431-437

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Attainment of Target Antibiotic Levels by Oral Treatment of Left-sided Infective Endocarditis: A POET Substudy

      Bock, M., Theut, A. M., van Hasselt, J. G. C., Wang, H., Fuursted, K., Hoiby, N., Lerche, C. J., Ihlemann, N., Gill, S., Christiansen, U., Nielsen, H. L., Lemming, L., Elming, H., Povlsen, J. A., Bruun, N. E., Hofsten, D., Fosbøl, E. L., Kober, L., Schultz, M., Pries-Heje, M. M. & 9 others, Kristensen, J. H., Christensen, J. J., Rosenvinge, F. S., Torp-Pedersen, Christian, Helweg-Larsen, J., Tønder, N., Iversen, Kasper, Bundgård, Henning & Moser, Claus Ernst, 2023, In: Clinical Infectious Diseases. 77, 2, p. 242–251 10 p., 168.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors

      Hentzer, M., Wu, H., Andersen, Jens Bo, Riedel, K., Rasmussen, T. B., Bagge, N., Kumar, N., Schembri, M. A., Song, Z., Kristoffersen, P., Manefield, M., Costerton, J. W., Molin, S., Eberl, L., Steinberg, P., Kjelleberg, S., Høiby, Niels & Givskov, Michael, 2003, In: EMBO Journal. 22, 15, p. 3803-15 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa

      van Gennip, M., Moser, C., Hultqvist, Louise Dahl, Bjarnsholt, Thomas, Calum, H., Jensen, Peter Østrup, Christophersen, L., Hougen, H. P., Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Dec 2009, In: Journal of Antimicrobial Chemotherapy. 64, 6, p. 1241-50 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Autoantibodies to pancreatic hsp60 precede the development of glucose intolerance in patients with cystic fibrosis

      Jensen, P., Johansen, Helle Krogh, Carmi, P., Høiby, Niels & Cohen, I. R., 2001, In: J. Autoimmunity. 17, p. 165-172

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Autofluorescence in samples obtained from chronic biofilm infections – “all that glitters is not gold”

      Eickhardt-Dalbøge, S. R., Kragh, K. N., Schrøder, S., Poulsen, Steen Seier, Sillesen, Henrik, Givskov, Michael, Høiby, Niels, Bjarnsholt, Thomas & Alhede, M., 2015, In: Pathogens and Disease. 73, 4, 4 p., ftv012.

      Research output: Contribution to journal › Letter › Research › peer-review

    8. Published

      Autologous fibrin sealant co-delivered with antibiotics is a robust method for topical antibiotic treatment after sinus surgery

      Aanæs, Kasper, Nielsen, Kim G., Arndal, E., von Buchwald, Christian, Pressler, T. & Høiby, Niels, 1 Feb 2021, In: Acta Oto-Laryngologica. 141, 2, p. 181-186 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Avidity of anti-P aeruginosa antibodies during chronic infection in patients with cystic fibrosis.

      Ciofu, Oana, Petersen, T. D., Jensen, P. & Høiby, Niels, 1999, In: Thorax. 54, 2, p. 141-4 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice

      Hoffmann, N., Lee, B., Hentzer, M., Rasmussen, T. B., Song, Z. J., Johansen, Helle Krogh, Givskov, M. C. & Høiby, Niels, 2007, In: Antimicrobial Agents and Chemotherapy. 51, 10, p. 3677-3687 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Azithromycin potentiates avian IgY effect against Pseudomonas aeruginosa in a murine pulmonary infection model

      Thomsen, K., Christophersen, L., Lerche, C. J., Holmgaard, D. B., Calum, Henrik Pierre, Høiby, Niels & Moser, Claus Ernst, 2021, In: International Journal of Antimicrobial Agents. 57, 1, 106213.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      A master of adaptation and survival strategies

      Høiby, Niels, Johansen, H. K., Moser, C., Ciofu, Oana & Rehm, B. H. A., 2008, Pseudomonas. Model Organism, Pathogen, Cell Factory. Weinheim: Wiley-VCH, Vol. 2. p. 25-44 19 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    13. Published

      Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data

      Yang, L., Rau, M. H., Yang, L., Høiby, Niels, Molin, S. & Jelsbak, L., 1 Jan 2011, In: B M C Microbiology. 11, p. 184

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Bacterial biofilm formation and treatment in soft tissue fillers

      Alhede, M., Er, O., Eickhardt, S., Kragh, K., Alhede, M., Hultqvist, Louise Dahl, Poulsen, Steen Seier, Givskov, Michael, Christensen, L. H., Høiby, Niels, Tvede, M. & Bjarnsholt, Thomas, 30 Jan 2014, In: Pathogens and Disease. 70, p. 339-346 8 p.

      Research output: Contribution to journal › Journal article › Research

    15. Published

      Bacterial evolution in PCD and CF patients follows the same mutational steps

      Sommer, L. M., Alanin, M. C., Marvig, R. L., Nielsen, Kim G., Høiby, Niels, von Buchwald, Christian, Molin, S. & Johansen, Helle Krogh, 2016, In: Scientific Reports. 6, 8 p., 28732.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation

      Brochmann, R. P., Toft, A., Ciofu, Oana, Briales, A., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, 2014, In: International Journal of Antimicrobial Agents. 43, 2, p. 140-147 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Bakteriebogen, oversættelse af "Bakterieboken" (Natur och Kultur) af K. Bergquist og F. Lundberg

      Høiby, Niels, 2002, København: Forlaget Forum.

      Research output: Book/Report › Book › Research › peer-review

    18. Published

      Bakteriel meningitis i Danmark 2002 og 2003: Landsdækkende registrering baseret pa laboratoriedata

      Meyer, Christian, Schonheyder, H. C., Bangsborg, J., Nielsen, X. C., Moller, J. K., Molbak, K., Korshin, A., Ronneberg, E., Koster-Rasmussen, R. & Høiby, Niels, 2007, In: Ugeskrift for læger. 169, 6, p. 503-506 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Bakteriel meningitis i Danmark 2002 og 2003. Landsdaekkende registrering baseret på laboratoriedata

      Meyer, Christian, Schønheyder, H. C., Bangsborg, Jette Marie, Nielsen, X. C., Møller, J. K., Mølbak, K., Korshin, A., Rønneberg, E., Køster-Rasmussen, Rasmus, Høiby, Niels & Dansk Bakteriel Meningitis Gruppe, D. B. M. G., 2007, In: Ugeskrift for Laeger. 169, 6, p. 503-6 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Bead-size directed distribution of Pseudomonas aeruginosa results in distinct inflammatory response in a mouse model of chronic lung infection

      Christophersen, L. J., Trøstrup, H., Damlund, D. S. M., Bjarnsholt, Thomas, Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, 2012, In: Experimental and clinical endocrinology. 170, 2, p. 222-30 10 p., 170.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Befolkningens behov udgangspunktet. Debatindlæg

      Høiby, Niels, 2002, In: Jyllandsposten. 10-4-2002, p. 1

      Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication

    22. Published

      Behandling af ukompliceret urinvejsinfektion

      Høiby, Niels, 1999, In: PLI. 16(12), p. 2-3

      Research output: Contribution to journal › Journal article › Research

    23. Published

      Behandlingssvigt med trimetoprim + sulfamethoxazol ved ukompliceret akut bakteriel cystitis og ved pyelonephritis hos kvinder med resistente bakterier. International Forskning

      Høiby, Niels & Tvede, M., 2002, In: Ugeskrift for læger. 164, p. 4672-4673 & 5284-5285

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Beregnede konsekvenser af den danske sulfonamidbehandling af ukomplicerede urinvejsinfektioner

      Høiby, Niels & Tvede, M., 2002, In: Ugeskrift for læger. 164, p. 2305

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Bestilt propaganda

      Høiby, Niels, 2002, In: Berlingske Tidende. 20-12-2002, p. 1

      Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication

    26. Published

      Biofilm Infections

      Bjarnsholt, Thomas (ed.), Moser, Claus Ernst (ed.), Jensen, Peter Østrup (ed.) & Høiby, Niels (ed.), 2010, Springer Publishing Company. 350 p.

      Research output: Book/Report › Book › Research › peer-review

    27. Published

      Biofilm infections

      Bjarnsholt, Thomas, Moser, Claus Ernst, Jensen, Peter Østrup & Høiby, Niels, 2011, Springer New York. 314 p.

      Research output: Book/Report › Book › Research › peer-review

    28. Published

      Biofilms and host response - helpful or harmful

      Moser, Claus Ernst, Pedersen, H. T., Lerche, C. J., Kolpen, Mette, Line, L., Thomsen, K., Høiby, Niels & Jensen, Peter Østrup, Apr 2017, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 125, 4, p. 320-338 19 p.

      Research output: Contribution to journal › Review › Research › peer-review

    29. Published

      Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

      Burmølle, Mette, Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.

      Research output: Contribution to journal › Review › Research › peer-review

    30. Published

      Biofilms of mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

      Kolpen, Mette, Jensen, Peter Østrup, Qvist, T., Kragh, K. N., Ravnholt, C., Fritz, Blaine Gabriel, Johansen, U. R., Bjarnsholt, Thomas & Høiby, Niels, 2020, In: Antimicrobial Agents and Chemotherapy. 64, 2, e01212.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils

      Fexby, S., Bjarnsholt, Thomas, Jensen, Peter Østrup, Roos, V., Høiby, Niels, Givskov, Michael & Klemm, P., 2006, In: Infection and Immunity. 75, 1, p. 30-4 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Blærebetændelse

      Høiby, Niels, 2010

      Research output: Other contribution › Net publication - Internet publication › Research

    33. Published

      Blærebetændelse. Patientvejledningen 1999

      Høiby, Niels, 1999, Oxford University Press.

      Research output: Book/Report › Book › Research

    34. Published

      C3 polymorphism in a Danish cystic fibrosis population and its possible association with antibody response

      Schiøtz, P. O., Høiby, Niels, Morling, Niels & Sørensen, H., 1978, In: Human Heredity. 28, 4, p. 293-300 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Calculated consequences of the Danish treatment of Staphylococcus aureus bacteremia and meningitis

      Høiby, Niels & Tvede, M., 2003, In: Ugeskrift for læger. 165(10), p. 1045-1046

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Calculated consequences of the Danish treatment of Staphylococcus aureus bacteremia and meningitis 2

      Høiby, Niels & Tvede, M., 2003, In: Ugeskrift for læger. 165(15), p. 1574

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study

      Alanin, M. C., Pressler, T., Aanæs, Kasper, Ekstrøm, Claus Thorn, Skov, M., Johansen, Helle Krogh, Nielsen, Kim G., von Buchwald, Christian & Høiby, Niels, 2018, In: Health Services Research. 1, 8, 5 p., e52.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection

      Hawdon, N. A., Aval, P. S., Barnes, R. J., Gravelle, S. K., Rosengren, J., Khan, S., Ciofu, Oana, Johansen, Helle Krogh, Høiby, Niels & Ulanova, M., 1 Jul 2010, In: FEMS Immunology and Medical Microbiology. 59, 2, p. 207-20 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Centennial celebrations of the Danish Pasteur Society

      Høiby, Niels & Bjarnsholt, Thomas, 2024, In: APMIS. 132, 1, p. 3

      Research output: Contribution to journal › Editorial › Research

    40. Published

      Characterization of paired mucoid/non-mucoid Pseudomonas aeruginosa isolates from Danish cystic fibrosis patients: antibiotic resistance, beta-lactamase activity and RiboPrinting.

      Ciofu, Oana, Fussing, V., Bagge, N., Koch, C. & Høiby, Niels, 2001, In: Journal of Antimicrobial Chemotherapy. 48, 3, p. 391-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Chicken IgY reduces the risk of Pseudomonas aeruginosa urinary tract infections in a murine model

      Schwartz, F. A., Christophersen, L., Thomsen, K., Baekdal, S., Pals Bendixen, M., Jørgensen, M., Bull Rasmussen, I. K., Laulund, A. S., Høiby, Niels & Moser, Claus Ernst, 2022, In: Frontiers in Microbiology. 13, 988386.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Christian Grams berømte farvemetode

      Høiby, Niels, 2007, In: Ugeskrift for læger. 169, 35, p. 2870-

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Chromosomal beta-lactamase is packaged into membrane vesicles and secreted from Pseudomonas aeruginosa.

      Ciofu, Oana, Beveridge, T. J., Kadurugamuwa, J., Walther-Rasmussen, J. & Høiby, Niels, 2000, In: Journal of Antimicrobial Chemotherapy. 45, 1, p. 9-13 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Chromosomal mechanisms of aminoglycoside resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients

      Islam, S., Oh, H., Jalal, S., Karpati, F., Ciofu, Oana, Høiby, Niels & Wretlind, B., 2009, In: Clinical Microbiology and Infection. 15, 1, p. 60-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines—implications for delayed wound closure?

      Trøstrup, H., Lerche, C. J., Christophersen, L. J., Thomsen, K., Jensen, Peter Østrup, Hougen, H. P., Høiby, Niels & Moser, Claus Ernst, Oct 2017, In: Pathogens and Disease. 75, 7, 10 p., ftx068.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Chronic Pseudomonas aeruginosa infection definition: EuroCareCF Working Group report

      Pressler, T., Bohmova, C., Conway, S., Dumcius, S., Hjelte, L., Høiby, Niels, Kollberg, H., Tümmler, B. & Vavrova, V., 1 Jun 2011, In: Journal of Cystic Fibrosis. 10 Suppl 2, p. S75-8

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Chronic Pseudomonas aeruginosa lung infection in normal and athymic rats

      Johansen, Helle Krogh, Espersen, F., Pedersen, S. S., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1993, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 101, 3, p. 207-225 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Chronic Pseudomonas aeruginosa lung infection is more severe in Th2 responding BALB/c mice compared to Th1 responding C3H/HeN mice

      Moser, Claus Ernst, Johansen, Helle Krogh, Song, Z., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1997, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 105, 11, p. 838-42 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Chronic infection with Achromobacter xylosoxidans in cystic fibrosis patients; a retrospective case control study

      Rønne Hansen, C., Pressler, T., Høiby, Niels & Gormsen, M., 2006, In: Journal of Cystic Fibrosis. 5, 4, p. 245-51 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Chronic infection with Stenotrophomonas maltophilia in patients with cystic fibrosis at the Copenhagen CF centre

      Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 17 Jun 2010. 0 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

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