Tim Holm Jakobsen
Associate Professor
Bacteriology
Nørre Allé 14
2200 København N
- 2012
- Published
Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model
Christensen, L., van Gennip, M., Jakobsen, Tim Holm, Alhede, M., Hougen, H. P., Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., May 2012, In: The Journal of antimicrobial chemotherapy. 67, 5, p. 1198-206 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Process for the manufacture of ajoene derivatives
Bjarnsholt, Thomas, Høiby, Niels, Jensen, Peter Østrup, Phipps, R., Shanmugham, Meenakshi, S., Alhede, M., Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Tanner, D., Larsen, Thomas, O. & Givskov, Michael, 14 Jun 2012, IPC No. C07C 323/ 65 A I, Patent No. WO2012076016, Priority date 8 Dec 2010, Priority No. EP20100194154Research output: Patent
- 2013
- Published
Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
Jakobsen, T. H., Hansen, M. A., Jensen, P. Ø., Hansen, L., Riber, L., Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, K., Burmølle, M., Moser, C. E., Kühl, M., Ciofu, O., Givskov, M., Sørensen, S. J. & 2 others, , 2013, In: P L o S One. 8, 7, 17 p., e68484.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of LasR ligands through a virtual screening approach
Skovstrup, S., Le Quement, S. T., Hansen, T., Jakobsen, Tim Holm, Harmsen, M., Tolker-Nielsen, Tim, Nielsen, T. E., Givskov, Michael & Taboureau, O., 2013, In: ChemMedChem. 8, 1, p. 157-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetic Model for Signal Binding to the Quorum Sensing Regulator LasR
Claussen, A., Jakobsen, Tim Holm, Bjarnsholt, Thomas, Givskov, Michael, Welch, M., Ferkinghoff-Borg, J. & Sams, T., 2013, In: International Journal of Molecular Sciences (Online). 14, 7, p. 13360-76 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors
Jakobsen, Tim Holm, Bjarnsholt, Thomas, Jensen, Peter Østrup, Givskov, Michael & Høiby, Niels, Jul 2013, In: Future Microbiology. 8, 7, p. 901-21 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Solid-phase synthesis and biological evaluation of N-dipeptido L-homoserine lactones as quorum sensing activators
Hansen, M. R., Le Quement, S. T., Jakobsen, Tim Holm, Skovstrup, S., Taboureau, O., Tolker-Nielsen, Tim, Givskov, Michael & Nielsen, T. E., 10 Feb 2014, In: ChemBioChem. 15, 3, p. 460-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative systems biology analysis to study the mode of action of the isothiocyanate compound Iberin on Pseudomonas aeruginosa
Tan, S. Y., Liu, Y., Chua, S. L., Vejborg, R. M., Jakobsen, Tim Holm, Chew, S. C., Li, Y., Nielsen, T. E., Tolker-Nielsen, Tim, Yang, L. & Givskov, Michael, Nov 2014, In: Antimicrobial Agents and Chemotherapy. 58, 11, p. 6648-59 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Triazole-containing N-acyl homoserine lactones targeting the quorum sensing system in Pseudomonas aeruginosa
Hansen, M. R., Jakobsen, Tim Holm, Bang, C. G., Cohrt, A. E., Hansen, C. L., Clausen, J. R. W., Le Quement, S. T., Tolker-Nielsen, Tim, Givskov, Michael & Nielsen, T., 2015, In: Bioorganic & Medicinal Chemistry. 23, 7, p. 1638-1650 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
A broad range quorum sensing inhibitor working through sRNA inhibition
Jakobsen, Tim Holm, Warming, A. N., Vejborg, R. M., Moscoso, J. A., Stegger, M., Lorenzen, F., Rybtke, Morten Levin, Andersen, Jens Bo, Petersen, R., Andersen, P. S., Nielsen, Thomas Eiland, Tolker-Nielsen, Tim, Filloux, A., Ingmer, Hanne & Givskov, Michael, 2017, In: Scientific Reports. 7, 1, 12 p., 9857.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9840851
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
Research output: Contribution to journal › Journal article › Research › peer-review
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323
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Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes
Research output: Contribution to journal › Review › Research › peer-review
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262
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Pseudomonas aeruginosa aggregate formation in an alginate bead model system exhibits In Vivo-like characteristics
Research output: Contribution to journal › Journal article › Research › peer-review
Published