Tim Holm Jakobsen
Associate Professor
Bacteriology
Nørre Allé 14
2200 København N
- Published
Novel and future treatment strategies
Alhede, M., Jakobsen, Tim Holm & Givskov, Michael, 1 Dec 2011, Biofilm Infections. Springer, p. 231-249 19 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Identification of small molecules that interfere with c-di-GMP signaling and induce dispersal of Pseudomonas aeruginosa biofilms
Andersen, Jens Bo, Hultqvist, Louise Dahl, Jansen, C. U., Jakobsen, Tim Holm, Nilsson, Carl Martin Peter, Rybtke, Morten Levin, Uhd, J., Fritz, Blaine Gabriel, Seifert, R., Berthelsen, J., Nielsen, Thomas Eiland, Qvortrup, K., Givskov, Michael & Tolker-Nielsen, Tim, 2021, In: npj Biofilms and Microbiomes. 7, 13 p., 59.Research output: Contribution to journal › Journal article › Research › peer-review
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Induction of native c-di-GMP phosphodiesterases leads to dispersal of Pseudomonas aeruginosa biofilms
Andersen, Jens Bo, Kragh, K. N., Hultqvist, Louise Dahl, Rybtke, Morten Levin, Nilsson, Carl Martin Peter, Jakobsen, Tim Holm, Givskov, Michael & Tolker-Nielsen, Tim, 2021, In: Antimicrobial Agents and Chemotherapy. 65, 4, e02431-20.Research output: Contribution to journal › Journal article › Research › peer-review
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Metagenomic and metatranscriptomic analysis of saliva reveals disease-associated microbiota in patients with periodontitis and dental caries
Midjord-Belstrøm, Daniel, Constancias, F., Liu, Y., Yang, L., Drautz-Moses, D. I., Schuster, S. C., Kohli, G. S., Jakobsen, Tim Holm, Holmstrup, Palle & Givskov, Michael, 2017, In: npj Biofilms and Microbiomes. 3, 8 p., 23.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect
Bjarnsholt, Thomas, van Gennip, M., Jakobsen, Tim Holm, Hultqvist, Louise Dahl, Jensen, Peter Østrup & Givskov, Michael, 2010, In: Nature Protocols (Print Edition). 5, 2, p. 282-93 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients
Bjarnsholt, Thomas, Jensen, Peter Østrup, Jakobsen, Tim Holm, Phipps, R., Nielsen, A. K., Rybtke, Morten Levin, Tolker-Nielsen, Tim, Givskov, Michael, Høiby, Niels, Ciofu, Oana & Scandinavian Cystic Fibrosis Study Consortium, S. C. F. S. C., 1 Jan 2010, In: PLoS ONE. 5, 4, p. e10115Research output: Contribution to journal › Journal article › Research › peer-review
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Process for the manufacture of ajoene derivatives
Bjarnsholt, Thomas, Høiby, Niels, Jensen, Peter Østrup, Phipps, R., Shanmugham, Meenakshi, S., Alhede, M., Hultqvist, Louise Dahl, Jakobsen, Tim Holm, Tanner, D., Larsen, Thomas, O. & Givskov, Michael, 14 Jun 2012, IPC No. C07C 323/ 65 A I, Patent No. WO2012076016, Priority date 8 Dec 2010, Priority No. EP20100194154Research output: Patent
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Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model
Christensen, L., van Gennip, M., Jakobsen, Tim Holm, Alhede, M., Hougen, H. P., Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael & Alhede, M., May 2012, In: The Journal of antimicrobial chemotherapy. 67, 5, p. 1198-206 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Imaging N-acyl homoserine lactone quorum sensing in vivo
Hultqvist, Louise Dahl, van Gennip, M., Jakobsen, Tim Holm, Givskov, Michael & Bjarnsholt, Thomas, 1 Jan 2011, In: Methods in Molecular Biology. 692, 2, p. 147-157 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetic Model for Signal Binding to the Quorum Sensing Regulator LasR
Claussen, A., Jakobsen, Tim Holm, Bjarnsholt, Thomas, Givskov, Michael, Welch, M., Ferkinghoff-Borg, J. & Sams, T., 2013, In: International Journal of Molecular Sciences (Online). 14, 7, p. 13360-76 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9840851
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Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes
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Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes
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Pseudomonas aeruginosa aggregate formation in an alginate bead model system exhibits In Vivo-like characteristics
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