Tim Tolker-Nielsen
Professor
Bacteriology
Blegdamsvej 3B, 2200 København N
Member of:
- 2017
- Published
High-throughput screening for compounds that modulate the cellular c-di-GMP level in bacteria
Groizeleau, J., Andersen, Jens Bo, Givskov, Michael, Berthelsen, J. & Tolker-Nielsen, Tim, Jan 2017, c-di-GMP Signaling: Methods and Protocols. Sauer, K. (ed.). Humana Press, Vol. 1657. p. 455-470 16 p. (Methods in Molecular Biology, Vol. 1657).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
A broad range quorum sensing inhibitor working through sRNA inhibition
Jakobsen, Tim Holm, Warming, A. N., Vejborg, R. M., Moscoso, J. A., Stegger, M., Lorenzen, F., Rybtke, Morten Levin, Andersen, Jens Bo, Petersen, R., Andersen, P. S., Nielsen, Thomas Eiland, Tolker-Nielsen, Tim, Filloux, A., Ingmer, Hanne & Givskov, Michael, 2017, In: Scientific Reports. 7, 1, 12 p., 9857.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial biofilm in chronic lesions of Hidradenitis Suppurativa
Ring, H. C., Bay, Lene, Nilsson, Carl Martin Peter, Kallenbach, K., Miller, I. M., Saunte, Ditte Marie, Bjarnsholt, Thomas, Tolker-Nielsen, Tim & Jemec, Gregor, 2017, In: British Journal of Dermatology. 176, 4, p. 993–1000Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cyclic-di-GMP is required for corneal infection by Pseudomonas aeruginosa and modulates host immunity
Hoong Yam, J. K., Aung, T. T., Chua, S. L., Cheng, Y., Kohli, G. S., Zhou, J., Constancias, F., Liu, Y., Cai, Z., Santillan Salido, M. M., Drautz-Moses, D. I., Rice, S. A., Schuster, S. C., Wu, B., Kjelleberg, S., Tolker-Nielsen, Tim, Beuerman, R. W., Givskov, Michael & Yang, L., 2017, bioRxiv, 35 p.Research output: Working paper › Preprint › Research
- Published
Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB
Fazli, M., Rybtke, Morten Levin, Steiner, E., Weidel, E., Berthelsen, J., Groizeleau, J. D. D., Bin, W., Zhi, B. Z., Yaming, Z., Kaever, V., Givskov, Michael, Hartmann, R. W., Eberl, L. & Tolker-Nielsen, Tim, 2017, In: MicrobiologyOpen. 6, 4, 13 p., e00480.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective proteomic analysis of antibiotic-tolerant cellular subpopulations in pseudomonas aeruginosa biofilms
Babin, B. M., Atangcho, L., van Eldijk, M. B., Sweredoski, M. J., Moradian, A., Hess, S., Tolker-Nielsen, Tim, Newman, D. K. & Tirrell, D. A., 2017, In: mBio. 8, 5, 16 p., e01593-17.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
The anti-cancerous drug doxorubicin decreases the c-di-GMP content in Pseudomonas aeruginosa but promotes biofilm formation
Groizeleau, J., Rybtke, Morten Levin, Andersen, Jens Bo, Berthelsen, J., Liu, Y., Yang, L., Nielsen, Thomas Eiland, Kaever, V., Givskov, Michael & Tolker-Nielsen, Tim, 1 Oct 2016, In: Microbiology. 162, 10, p. 1797-1807 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dlt genes play a role in antimicrobial tolerance of Streptococcus mutans biofilms
Nilsson, Carl Martin Peter, Rybtke, Morten Levin, Givskov, Michael, Høiby, Niels, Twetman, Svante & Tolker-Nielsen, Tim, Sep 2016, In: International Journal of Antimicrobial Agents. 48, 3, p. 298–304Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa Microcolonies in Coronary Thrombi from Patients with ST-Segment Elevation Myocardial Infarction
Hansen, G. M., Midjord-Belstrøm, Daniel, Nilsson, Carl Martin Peter, Helqvist, S., Nielsen, Claus Henrik, Holmstrup, Palle, Tolker-Nielsen, Tim, Givskov, Michael & Hansen, Peter Riis, 2016, In: P L o S One. 11, 12, 13 p., e0168771.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms
Chua, S. L., Yam, J. K. H., Hao, P., Adav, S. S., Salido, M. M., Liu, Y., Givskov, Michael, Sze, S. K., Tolker-Nielsen, Tim & Yang, L., 2016, In: Nature Communications. 7, 11 p., 10750.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Pigments influence the tolerance of Pseudomonas aeruginosa PAO1 to photodynamically induced oxidative stress
Orlandi, V. T., Bolognese, F., Chiodaroli, L., Tolker-Nielsen, Tim & Barbieri, P., Dec 2015, In: Microbiology. 161, 12, p. 2298-309 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The LapG protein plays a role in Pseudomonas aeruginosa biofilm formation by controlling the presence of the CdrA adhesin on the cell surface
Rybtke, Morten Levin, Berthelsen, J., Yang, L., Høiby, Niels, Givskov, Michael & Tolker-Nielsen, Tim, Dec 2015, In: MicrobiologyOpen. 4, 6, p. 917-930 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange
Hmelo, L. R., Borlee, B. R., Almblad, H., Love, M. E., Randall, T. E., Tseng, B. S., Lin, C., Irie, Y., Storek, K. M., Yang, J. J., Siehnel, R. J., Howell, P. L., Singh, P. K., Tolker-Nielsen, Tim, Parsek, M. R., Schweizer, H. P. & Harrison, J. J., Nov 2015, In: Nature Protocols (Print). 10, 11, p. 1820-41 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The bactericidal activity of β-lactam antibiotics is increased by metabolizable sugar species
Thorsing, M., Bentin, Thomas, Givskov, Michael, Tolker-Nielsen, Tim & Goltermann, Lise, Oct 2015, In: Microbiology. 161, 10, p. 1999-2007 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro and in vivo generation and characterization of Pseudomonas aeruginosa biofilm-dispersed cells via c-di-GMP manipulation
Chua, S. L., Hultqvist, Louise Dahl, Yuan, M., Rybtke, Morten Levin, Nielsen, Thomas Eiland, Givskov, Michael, Tolker-Nielsen, Tim & Yang, L., Aug 2015, In: Nature Protocols (Print). 10, 8, p. 1165-80 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cranberry (Vaccinium macrocarpon) oligosaccharides decrease biofilm formation by uropathogenic Escherichia coli
Sun, J., Marais, J. P. J., Khoo, C., LaPlante, K., Vejborg, R. M., Givskov, Michael, Tolker-Nielsen, Tim, Seeram, N. P. & Rowley, D. C., Aug 2015, In: Journal of Functional Foods. 17, p. 235-242 8 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Erratum for Almblad et al., The Cyclic AMP-Vfr Signaling Pathway in Pseudomonas aeruginosa Is Inhibited by Cyclic Di-GMP
Almblad, H., Harrison, J. J., Rybtke, Morten Levin, Groizeleau, J., Givskov, Michael, Parsek, M. R. & Tolker-Nielsen, Tim, Aug 2015, In: Journal of Bacteriology. 197, 16, p. 2731 1 p.Research output: Contribution to journal › Comment/debate › Research
- Published
The Cyclic AMP-Vfr Signaling Pathway in Pseudomonas aeruginosa Is Inhibited by Cyclic Di-GMP
Almblad, H., Harrison, J. J., Rybtke, Morten Levin, Groizeleau, J., Givskov, Michael, Parsek, M. R. & Tolker-Nielsen, Tim, Jul 2015, In: Journal of Bacteriology. 197, 13, p. 2190-200 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Viable Bacteria Associated with Red Blood Cells and Plasma in Freshly Drawn Blood Donations
Damgaard, Christian, Magnussen, K., Enevold, Christian, Nilsson, Carl Martin Peter, Tolker-Nielsen, Tim, Holmstrup, Palle & Nielsen, Claus Henrik, 9 Mar 2015, In: P L o S One. 10, 3, p. 1-9 9 p., e0120826.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudomonas aeruginosa LysR PA4203 regulator NmoR acts as a repressor of the PA4202 nmoA gene, encoding a nitronate monooxygenase
Vercammen, K., Wei, Q., Charlier, D., Dötsch, A., Haüssler, S., Schulz, S., Salvi, F., Gadda, G., Spain, J., Rybtke, Morten Levin, Tolker-Nielsen, Tim, Dingemans, J., Ye, L. & Cornelis, P., Mar 2015, In: Journal of Bacteriology. 197, 6, p. 1026-39 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilm Development
Tolker-Nielsen, Tim, Mar 2015, In: Microbiology Spectrum. 3, 2, 12 p., MB-0001-2014.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biofilm development
Tolker-Nielsen, Tim, 1 Jan 2015, Microbial Biofilms. Wiley-Interscience, p. 51-66 16 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Pseudomonas aeruginosa Biofilm Infections: Community Structure, Antimicrobial Tolerance and Immune Response
Rybtke, Morten Levin, Hultqvist, Louise Dahl, Givskov, Michael & Tolker-Nielsen, Tim, 2015, In: Journal of Molecular Biology. 427, 23, p. 3628-3645Research output: Contribution to journal › Review › Research › peer-review
- Published
Absence of Bacteria on Coronary Angioplasty Balloons from Unselected Patients: Results with Use of a High Sensitivity Polymerase Chain Reaction Assay
Hansen, G. M., Nilsson, M., Nielsen, Claus Henrik, Holmstrup, Palle, Helqvist, S., Tolker-Nielsen, Tim, Givskov, Michael & Hansen, Peter Riis, 2015, In: PloS one. 10, 12, p. 1-11 11 p., e0145657.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients
Ciofu, Oana, Tolker-Nielsen, Tim, Jensen, Peter Østrup, Wang, H. & Høiby, Niels, 2015, In: Advanced Drug Delivery Reviews. 85, p. 7-23 17 p.Research output: Contribution to journal › Review › Research › peer-review
ID: 8656938
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Colony morphology and transcriptome profiling of Pseudomonas putida KT2440 and its mutants deficient in alginate or all EPS synthesis under controlled matric potentials
Research output: Contribution to journal › Journal article › Research › peer-review
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C-di-GMP regulates Pseudomonas aeruginosa stress response to tellurite during both planktonic and biofilm modes of growth
Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes
Research output: Contribution to journal › Review › Research › peer-review
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