Advances in nucleic acid-based diagnostics of bacterial infections.

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Advances in nucleic acid-based diagnostics of bacterial infections. / Barken, Kim B; Haagensen, Janus A J; Tolker-Nielsen, Tim.

In: Clinica Chimica Acta, Vol. 384, No. 1-2, 2007, p. 1-11.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Barken, KB, Haagensen, JAJ & Tolker-Nielsen, T 2007, 'Advances in nucleic acid-based diagnostics of bacterial infections.', Clinica Chimica Acta, vol. 384, no. 1-2, pp. 1-11. https://doi.org/10.1016/j.cca.2007.07.004

APA

Barken, K. B., Haagensen, J. A. J., & Tolker-Nielsen, T. (2007). Advances in nucleic acid-based diagnostics of bacterial infections. Clinica Chimica Acta, 384(1-2), 1-11. https://doi.org/10.1016/j.cca.2007.07.004

Vancouver

Barken KB, Haagensen JAJ, Tolker-Nielsen T. Advances in nucleic acid-based diagnostics of bacterial infections. Clinica Chimica Acta. 2007;384(1-2):1-11. https://doi.org/10.1016/j.cca.2007.07.004

Author

Barken, Kim B ; Haagensen, Janus A J ; Tolker-Nielsen, Tim. / Advances in nucleic acid-based diagnostics of bacterial infections. In: Clinica Chimica Acta. 2007 ; Vol. 384, No. 1-2. pp. 1-11.

Bibtex

@article{d6510980bd3e11dd8e02000ea68e967b,
title = "Advances in nucleic acid-based diagnostics of bacterial infections.",
abstract = "Methods for rapid detection of infectious bacteria and antimicrobial-resistant pathogens have evolved significantly over the last decade. Many of the new procedures are nucleic acid-based and replace conventional diagnostic methods like culturing which is time consuming especially with fastidious and slow growing microorganisms. The widespread use of antibiotics has resulted in an increased number of cases with resistant microorganisms such as methicillin-resistant Staphylococcus aureus, vancomycin resistant enterococci, and multidrug-resistant Mycobacterium tuberculosis. Rapid detection of these pathogens is important to isolate patients and prevent further spreading of the diseases. Newly developed diagnostic procedures are superior with respect to turnaround time, sensitivity and specificity. Methods like multiplex real time PCR and different array-based technologies offer the possibility of multiparameter assays where several pathogens and antibiotic resistance genes can be detected simultaneously.",
author = "Barken, {Kim B} and Haagensen, {Janus A J} and Tim Tolker-Nielsen",
note = "Keywords: Bacterial Infections; DNA, Bacterial; Humans; In Situ Hybridization; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; RNA, Bacterial; RNA, Ribosomal, 16S",
year = "2007",
doi = "10.1016/j.cca.2007.07.004",
language = "English",
volume = "384",
pages = "1--11",
journal = "Clinica Chimica Acta",
issn = "0009-8981",
publisher = "Elsevier",
number = "1-2",

}

RIS

TY - JOUR

T1 - Advances in nucleic acid-based diagnostics of bacterial infections.

AU - Barken, Kim B

AU - Haagensen, Janus A J

AU - Tolker-Nielsen, Tim

N1 - Keywords: Bacterial Infections; DNA, Bacterial; Humans; In Situ Hybridization; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; RNA, Bacterial; RNA, Ribosomal, 16S

PY - 2007

Y1 - 2007

N2 - Methods for rapid detection of infectious bacteria and antimicrobial-resistant pathogens have evolved significantly over the last decade. Many of the new procedures are nucleic acid-based and replace conventional diagnostic methods like culturing which is time consuming especially with fastidious and slow growing microorganisms. The widespread use of antibiotics has resulted in an increased number of cases with resistant microorganisms such as methicillin-resistant Staphylococcus aureus, vancomycin resistant enterococci, and multidrug-resistant Mycobacterium tuberculosis. Rapid detection of these pathogens is important to isolate patients and prevent further spreading of the diseases. Newly developed diagnostic procedures are superior with respect to turnaround time, sensitivity and specificity. Methods like multiplex real time PCR and different array-based technologies offer the possibility of multiparameter assays where several pathogens and antibiotic resistance genes can be detected simultaneously.

AB - Methods for rapid detection of infectious bacteria and antimicrobial-resistant pathogens have evolved significantly over the last decade. Many of the new procedures are nucleic acid-based and replace conventional diagnostic methods like culturing which is time consuming especially with fastidious and slow growing microorganisms. The widespread use of antibiotics has resulted in an increased number of cases with resistant microorganisms such as methicillin-resistant Staphylococcus aureus, vancomycin resistant enterococci, and multidrug-resistant Mycobacterium tuberculosis. Rapid detection of these pathogens is important to isolate patients and prevent further spreading of the diseases. Newly developed diagnostic procedures are superior with respect to turnaround time, sensitivity and specificity. Methods like multiplex real time PCR and different array-based technologies offer the possibility of multiparameter assays where several pathogens and antibiotic resistance genes can be detected simultaneously.

U2 - 10.1016/j.cca.2007.07.004

DO - 10.1016/j.cca.2007.07.004

M3 - Journal article

C2 - 17689512

VL - 384

SP - 1

EP - 11

JO - Clinica Chimica Acta

JF - Clinica Chimica Acta

SN - 0009-8981

IS - 1-2

ER -

ID: 8780084