Biofilms and host response - helpful or harmful
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Biofilms and host response - helpful or harmful. / Moser, Claus; Pedersen, Hannah Trøstrup; Lerche, Christian Johann; Kolpen, Mette; Line, Laura; Thomsen, Kim; Høiby, Niels; Jensen, Peter Østrup.
In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica, Vol. 125, No. 4, 04.2017, p. 320-338.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Biofilms and host response - helpful or harmful
AU - Moser, Claus
AU - Pedersen, Hannah Trøstrup
AU - Lerche, Christian Johann
AU - Kolpen, Mette
AU - Line, Laura
AU - Thomsen, Kim
AU - Høiby, Niels
AU - Jensen, Peter Østrup
N1 - © 2017 APMIS. Published by John Wiley & Sons Ltd.
PY - 2017/4
Y1 - 2017/4
N2 - Biofilm infections are one of the modern medical world's greatest challenges. Probably, all non-obligate intracellular bacteria and fungi can establish biofilms. In addition, there are numerous biofilm-related infections, both foreign body-related and non-foreign body-related. Although biofilm infections can present in numerous ways, one common feature is involvement of the host response with significant impact on the course. A special characteristic is the synergy of the innate and the acquired immune responses for the induced pathology. Here, we review the impact of the host response for the course of biofilm infections, with special focus on cystic fibrosis, chronic wounds and infective endocarditis.
AB - Biofilm infections are one of the modern medical world's greatest challenges. Probably, all non-obligate intracellular bacteria and fungi can establish biofilms. In addition, there are numerous biofilm-related infections, both foreign body-related and non-foreign body-related. Although biofilm infections can present in numerous ways, one common feature is involvement of the host response with significant impact on the course. A special characteristic is the synergy of the innate and the acquired immune responses for the induced pathology. Here, we review the impact of the host response for the course of biofilm infections, with special focus on cystic fibrosis, chronic wounds and infective endocarditis.
KW - Biofilms
KW - Cystic Fibrosis
KW - Host-Pathogen Interactions
KW - Humans
KW - Immunity
KW - Pseudomonas Infections
KW - Pseudomonas aeruginosa
KW - Journal Article
KW - Review
U2 - 10.1111/apm.12674
DO - 10.1111/apm.12674
M3 - Review
C2 - 28407429
VL - 125
SP - 320
EP - 338
JO - A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica
JF - A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica
SN - 0903-4641
IS - 4
ER -
ID: 179276535