Combating biofilms
Research output: Contribution to journal › Journal article › Research › peer-review
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Combating biofilms. / Yang, Liang; Liu, Yang; Wu, Hong; Song, Zhijun; Høiby, Niels; Molin, Søren; Givskov, Michael.
In: F E M S Immunology and Medical Microbiology, Vol. 65, No. 2, 2012, p. 146–157.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Combating biofilms
AU - Yang, Liang
AU - Liu, Yang
AU - Wu, Hong
AU - Song, Zhijun
AU - Høiby, Niels
AU - Molin, Søren
AU - Givskov, Michael
N1 - © 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.
PY - 2012
Y1 - 2012
N2 - Biofilms are complex microbial communities consisting of microcolonies embedded in a matrix of self-produced polymer substances. Biofilm cells show much greater resistance to environmental challenges including antimicrobial agents than their free-living counterparts. The biofilm mode of life is believed to significantly contribute to successful microbial survival in hostile environments. Conventional treatment, disinfection and cleaning strategies do not proficiently deal with biofilm-related problems, such as persistent infections and contamination of food production facilities. In this review, strategies to control biofilms are discussed, including those of inhibition of microbial attachment, interference of biofilm structure development and differentiation, killing of biofilm cells and induction of biofilm dispersion.
AB - Biofilms are complex microbial communities consisting of microcolonies embedded in a matrix of self-produced polymer substances. Biofilm cells show much greater resistance to environmental challenges including antimicrobial agents than their free-living counterparts. The biofilm mode of life is believed to significantly contribute to successful microbial survival in hostile environments. Conventional treatment, disinfection and cleaning strategies do not proficiently deal with biofilm-related problems, such as persistent infections and contamination of food production facilities. In this review, strategies to control biofilms are discussed, including those of inhibition of microbial attachment, interference of biofilm structure development and differentiation, killing of biofilm cells and induction of biofilm dispersion.
U2 - 10.1111/j.1574-695X.2011.00858.x
DO - 10.1111/j.1574-695X.2011.00858.x
M3 - Journal article
C2 - 22066868
VL - 65
SP - 146
EP - 157
JO - Pathogens and Disease
JF - Pathogens and Disease
SN - 2049-632X
IS - 2
ER -
ID: 38230039