Diastereoselective synthesis of novel heterocyclic scaffolds through tandem Petasis 3-component/intramolecular Diels-Alder and ROM-RCM reactions

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A high-yielding, stereoselective and extraordinarily complexity-generating Petasis 3-component/intramolecular Diels–Alder reaction has been developed. In combination with ROM–RCM, rapid access to complex sp3-rich heterocyclic scaffolds amenable to subsequent functionalization and library synthesis is provided.
Original languageEnglish
JournalChemical Communications
Volume53
Issue number68
Pages (from-to)9410-9413
ISSN1359-7345
DOIs
Publication statusPublished - 2017

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