Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin. / Brinch, Karoline Sidelmann; Tulkens, Paul M; Van Bambeke, Francoise; Frimodt-Møller, Niels; Høiby, Niels; Kristensen, Hans-Henrik.

In: Journal of Antimicrobial Chemotherapy, Vol. 65, No. 8, 01.08.2010, p. 1720-4.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Brinch, KS, Tulkens, PM, Van Bambeke, F, Frimodt-Møller, N, Høiby, N & Kristensen, H-H 2010, 'Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin', Journal of Antimicrobial Chemotherapy, vol. 65, no. 8, pp. 1720-4. https://doi.org/10.1093/jac/dkq159, https://doi.org/10.1093/jac/dkq159

APA

Brinch, K. S., Tulkens, P. M., Van Bambeke, F., Frimodt-Møller, N., Høiby, N., & Kristensen, H-H. (2010). Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin. Journal of Antimicrobial Chemotherapy, 65(8), 1720-4. https://doi.org/10.1093/jac/dkq159, https://doi.org/10.1093/jac/dkq159

Vancouver

Brinch KS, Tulkens PM, Van Bambeke F, Frimodt-Møller N, Høiby N, Kristensen H-H. Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin. Journal of Antimicrobial Chemotherapy. 2010 Aug 1;65(8):1720-4. https://doi.org/10.1093/jac/dkq159, https://doi.org/10.1093/jac/dkq159

Author

Brinch, Karoline Sidelmann ; Tulkens, Paul M ; Van Bambeke, Francoise ; Frimodt-Møller, Niels ; Høiby, Niels ; Kristensen, Hans-Henrik. / Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin. In: Journal of Antimicrobial Chemotherapy. 2010 ; Vol. 65, No. 8. pp. 1720-4.

Bibtex

@article{9a7c9b6411f4425cbce6a17729f3b29b,
title = "Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin",
abstract = "Staphylococcus aureus survives inside eukaryotic cells. Our objective was to assess the activity of NZ2114, a novel peptidic antibiotic, against intracellular S. aureus in comparison with established antistaphylococcal agents acting on the bacterial envelope with a distinct mechanism.",
keywords = "Anti-Bacterial Agents, Cell Line, Colony Count, Microbial, Daptomycin, Humans, Microbial Sensitivity Tests, Microbial Viability, Monocytes, Peptides, Staphylococcus aureus, Vancomycin",
author = "Brinch, {Karoline Sidelmann} and Tulkens, {Paul M} and {Van Bambeke}, Francoise and Niels Frimodt-M{\o}ller and Niels H{\o}iby and Hans-Henrik Kristensen",
year = "2010",
month = aug,
day = "1",
doi = "10.1093/jac/dkq159",
language = "English",
volume = "65",
pages = "1720--4",
journal = "Journal of Antimicrobial Chemotherapy",
issn = "0305-7453",
publisher = "Oxford University Press",
number = "8",

}

RIS

TY - JOUR

T1 - Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin

AU - Brinch, Karoline Sidelmann

AU - Tulkens, Paul M

AU - Van Bambeke, Francoise

AU - Frimodt-Møller, Niels

AU - Høiby, Niels

AU - Kristensen, Hans-Henrik

PY - 2010/8/1

Y1 - 2010/8/1

N2 - Staphylococcus aureus survives inside eukaryotic cells. Our objective was to assess the activity of NZ2114, a novel peptidic antibiotic, against intracellular S. aureus in comparison with established antistaphylococcal agents acting on the bacterial envelope with a distinct mechanism.

AB - Staphylococcus aureus survives inside eukaryotic cells. Our objective was to assess the activity of NZ2114, a novel peptidic antibiotic, against intracellular S. aureus in comparison with established antistaphylococcal agents acting on the bacterial envelope with a distinct mechanism.

KW - Anti-Bacterial Agents

KW - Cell Line

KW - Colony Count, Microbial

KW - Daptomycin

KW - Humans

KW - Microbial Sensitivity Tests

KW - Microbial Viability

KW - Monocytes

KW - Peptides

KW - Staphylococcus aureus

KW - Vancomycin

U2 - 10.1093/jac/dkq159

DO - 10.1093/jac/dkq159

M3 - Journal article

C2 - 20534628

VL - 65

SP - 1720

EP - 1724

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

SN - 0305-7453

IS - 8

ER -

ID: 33917973