Microbial motility involvement in biofilm structure formation--a 3D modelling study.

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Microbial motility involvement in biofilm structure formation--a 3D modelling study. / Picioreanu, C; Kreft, J U; Klausen, M; Haagensen, J A J; Tolker-Nielsen, Tim; Molin, S.

In: Water Science and Technology, Vol. 55, No. 8-9, 2007, p. 337-43.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Picioreanu, C, Kreft, JU, Klausen, M, Haagensen, JAJ, Tolker-Nielsen, T & Molin, S 2007, 'Microbial motility involvement in biofilm structure formation--a 3D modelling study.', Water Science and Technology, vol. 55, no. 8-9, pp. 337-43.

APA

Picioreanu, C., Kreft, J. U., Klausen, M., Haagensen, J. A. J., Tolker-Nielsen, T., & Molin, S. (2007). Microbial motility involvement in biofilm structure formation--a 3D modelling study. Water Science and Technology, 55(8-9), 337-43.

Vancouver

Picioreanu C, Kreft JU, Klausen M, Haagensen JAJ, Tolker-Nielsen T, Molin S. Microbial motility involvement in biofilm structure formation--a 3D modelling study. Water Science and Technology. 2007;55(8-9):337-43.

Author

Picioreanu, C ; Kreft, J U ; Klausen, M ; Haagensen, J A J ; Tolker-Nielsen, Tim ; Molin, S. / Microbial motility involvement in biofilm structure formation--a 3D modelling study. In: Water Science and Technology. 2007 ; Vol. 55, No. 8-9. pp. 337-43.

Bibtex

@article{650b1f80bd3f11dd8e02000ea68e967b,
title = "Microbial motility involvement in biofilm structure formation--a 3D modelling study.",
abstract = "A computational model explaining formation of mushroom-like biofilm colonies is proposed in this study. The biofilm model combines for the first time cell growth with twitching motility in a three-dimensional individual-based approach. Model simulations describe the tendency of motile cells to form flat biofilms spreading out on the substratum, in contrast with the immotile variants that form only round colonies. These computational results are in good qualitative agreement with the experimental data obtained from Pseudomonas aeruginosa biofilms grown in flowcells. Simulations reveal that motile cells can possess a serious ecological advantage by becoming less affected by mass transfer limitations. Twitching motility alone appears to be insufficient to generate mushroom-like biofilm structures with caps on stalks. Rather, a substrate limitation-induced detachment of motile cells followed by reattachment could explain this intriguing effect leading to higher-level biofilm structure.",
author = "C Picioreanu and Kreft, {J U} and M Klausen and Haagensen, {J A J} and Tim Tolker-Nielsen and S Molin",
note = "Keywords: Bacterial Adhesion; Biofilms; Models, Biological; Pseudomonas aeruginosa",
year = "2007",
language = "English",
volume = "55",
pages = "337--43",
journal = "Water Science and Technology",
issn = "0273-1223",
publisher = "I W A Publishing",
number = "8-9",

}

RIS

TY - JOUR

T1 - Microbial motility involvement in biofilm structure formation--a 3D modelling study.

AU - Picioreanu, C

AU - Kreft, J U

AU - Klausen, M

AU - Haagensen, J A J

AU - Tolker-Nielsen, Tim

AU - Molin, S

N1 - Keywords: Bacterial Adhesion; Biofilms; Models, Biological; Pseudomonas aeruginosa

PY - 2007

Y1 - 2007

N2 - A computational model explaining formation of mushroom-like biofilm colonies is proposed in this study. The biofilm model combines for the first time cell growth with twitching motility in a three-dimensional individual-based approach. Model simulations describe the tendency of motile cells to form flat biofilms spreading out on the substratum, in contrast with the immotile variants that form only round colonies. These computational results are in good qualitative agreement with the experimental data obtained from Pseudomonas aeruginosa biofilms grown in flowcells. Simulations reveal that motile cells can possess a serious ecological advantage by becoming less affected by mass transfer limitations. Twitching motility alone appears to be insufficient to generate mushroom-like biofilm structures with caps on stalks. Rather, a substrate limitation-induced detachment of motile cells followed by reattachment could explain this intriguing effect leading to higher-level biofilm structure.

AB - A computational model explaining formation of mushroom-like biofilm colonies is proposed in this study. The biofilm model combines for the first time cell growth with twitching motility in a three-dimensional individual-based approach. Model simulations describe the tendency of motile cells to form flat biofilms spreading out on the substratum, in contrast with the immotile variants that form only round colonies. These computational results are in good qualitative agreement with the experimental data obtained from Pseudomonas aeruginosa biofilms grown in flowcells. Simulations reveal that motile cells can possess a serious ecological advantage by becoming less affected by mass transfer limitations. Twitching motility alone appears to be insufficient to generate mushroom-like biofilm structures with caps on stalks. Rather, a substrate limitation-induced detachment of motile cells followed by reattachment could explain this intriguing effect leading to higher-level biofilm structure.

M3 - Journal article

C2 - 17547003

VL - 55

SP - 337

EP - 343

JO - Water Science and Technology

JF - Water Science and Technology

SN - 0273-1223

IS - 8-9

ER -

ID: 8780107