Prosthesis infections after orthopedic joint replacement: the possible role of bacterial biofilms

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Prosthesis infections after orthopedic joint replacement : the possible role of bacterial biofilms. / Song, Zhijun; Borgwardt, Lotte; Høiby, Niels; Wu, Hong; Sørensen, Torben Sandberg; Borgwardt, Arne.

In: Orthopedic Reviews, Vol. 5, No. 2, 07.06.2013, p. 65-71.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Song, Z, Borgwardt, L, Høiby, N, Wu, H, Sørensen, TS & Borgwardt, A 2013, 'Prosthesis infections after orthopedic joint replacement: the possible role of bacterial biofilms', Orthopedic Reviews, vol. 5, no. 2, pp. 65-71. https://doi.org/10.4081/or.2013.e14

APA

Song, Z., Borgwardt, L., Høiby, N., Wu, H., Sørensen, T. S., & Borgwardt, A. (2013). Prosthesis infections after orthopedic joint replacement: the possible role of bacterial biofilms. Orthopedic Reviews, 5(2), 65-71. https://doi.org/10.4081/or.2013.e14

Vancouver

Song Z, Borgwardt L, Høiby N, Wu H, Sørensen TS, Borgwardt A. Prosthesis infections after orthopedic joint replacement: the possible role of bacterial biofilms. Orthopedic Reviews. 2013 Jun 7;5(2):65-71. https://doi.org/10.4081/or.2013.e14

Author

Song, Zhijun ; Borgwardt, Lotte ; Høiby, Niels ; Wu, Hong ; Sørensen, Torben Sandberg ; Borgwardt, Arne. / Prosthesis infections after orthopedic joint replacement : the possible role of bacterial biofilms. In: Orthopedic Reviews. 2013 ; Vol. 5, No. 2. pp. 65-71.

Bibtex

@article{3de1a84779764e7484e96fff020dc24b,
title = "Prosthesis infections after orthopedic joint replacement: the possible role of bacterial biofilms",
abstract = "Prosthesis-related infection is a serious complication for patients after orthopedic joint replacement, which is currently difficult to treat with antibiotic therapy. Consequently, in most cases, removal of the infected prosthesis is the only solution to cure the infection. It is, therefore, important to understand the comprehensive interaction between the microbiological situation and the host immune responses that lead to prosthesis infections. Evidence indicates that prosthesis infections are actually biofilm-correlated infections that are highly resistant to antibiotic treatment and the host immune responses. The authors reviewed the related literature in the context of their clinical experience, and discussed the possible etiology and mechanism leading to the infections, especially problems related to bacterial biofilm, and prophylaxis and treatment of infection, including both microbiological and surgical measures. Recent progress in research into bacterial biofilm and possible future treatment options of prosthesis-related infections are discussed.",
author = "Zhijun Song and Lotte Borgwardt and Niels H{\o}iby and Hong Wu and S{\o}rensen, {Torben Sandberg} and Arne Borgwardt",
year = "2013",
month = jun,
day = "7",
doi = "10.4081/or.2013.e14",
language = "English",
volume = "5",
pages = "65--71",
journal = "Orthopedic Reviews",
issn = "2035-8237",
publisher = "Pagepress",
number = "2",

}

RIS

TY - JOUR

T1 - Prosthesis infections after orthopedic joint replacement

T2 - the possible role of bacterial biofilms

AU - Song, Zhijun

AU - Borgwardt, Lotte

AU - Høiby, Niels

AU - Wu, Hong

AU - Sørensen, Torben Sandberg

AU - Borgwardt, Arne

PY - 2013/6/7

Y1 - 2013/6/7

N2 - Prosthesis-related infection is a serious complication for patients after orthopedic joint replacement, which is currently difficult to treat with antibiotic therapy. Consequently, in most cases, removal of the infected prosthesis is the only solution to cure the infection. It is, therefore, important to understand the comprehensive interaction between the microbiological situation and the host immune responses that lead to prosthesis infections. Evidence indicates that prosthesis infections are actually biofilm-correlated infections that are highly resistant to antibiotic treatment and the host immune responses. The authors reviewed the related literature in the context of their clinical experience, and discussed the possible etiology and mechanism leading to the infections, especially problems related to bacterial biofilm, and prophylaxis and treatment of infection, including both microbiological and surgical measures. Recent progress in research into bacterial biofilm and possible future treatment options of prosthesis-related infections are discussed.

AB - Prosthesis-related infection is a serious complication for patients after orthopedic joint replacement, which is currently difficult to treat with antibiotic therapy. Consequently, in most cases, removal of the infected prosthesis is the only solution to cure the infection. It is, therefore, important to understand the comprehensive interaction between the microbiological situation and the host immune responses that lead to prosthesis infections. Evidence indicates that prosthesis infections are actually biofilm-correlated infections that are highly resistant to antibiotic treatment and the host immune responses. The authors reviewed the related literature in the context of their clinical experience, and discussed the possible etiology and mechanism leading to the infections, especially problems related to bacterial biofilm, and prophylaxis and treatment of infection, including both microbiological and surgical measures. Recent progress in research into bacterial biofilm and possible future treatment options of prosthesis-related infections are discussed.

U2 - 10.4081/or.2013.e14

DO - 10.4081/or.2013.e14

M3 - Journal article

C2 - 23888204

VL - 5

SP - 65

EP - 71

JO - Orthopedic Reviews

JF - Orthopedic Reviews

SN - 2035-8237

IS - 2

ER -

ID: 49277768