Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies

Research output: Contribution to journal › Journal article › Research › peer-review

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Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies. / Hassett, Daniel J; Korfhagen, Thomas R; Irvin, Randall T; Schurr, Michael J; Sauer, Karin; Lau, Gee W; Sutton, Mark D; Yu, Hongwei; Høiby, Niels.

In: Expert Opinion On Therapeutic Targets, Vol. 14, No. 2, 01.02.2010, p. 117-30.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Hassett, DJ, Korfhagen, TR, Irvin, RT, Schurr, MJ, Sauer, K, Lau, GW, Sutton, MD, Yu, H & Høiby, N 2010, 'Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies', Expert Opinion On Therapeutic Targets, vol. 14, no. 2, pp. 117-30. https://doi.org/10.1517/14728220903454988

APA

Hassett, D. J., Korfhagen, T. R., Irvin, R. T., Schurr, M. J., Sauer, K., Lau, G. W., Sutton, M. D., Yu, H., & Høiby, N. (2010). Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies. Expert Opinion On Therapeutic Targets, 14(2), 117-30. https://doi.org/10.1517/14728220903454988

Vancouver

Hassett DJ, Korfhagen TR, Irvin RT, Schurr MJ, Sauer K, Lau GW et al. Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies. Expert Opinion On Therapeutic Targets. 2010 Feb 1;14(2):117-30. https://doi.org/10.1517/14728220903454988

Author

Hassett, Daniel J ; Korfhagen, Thomas R ; Irvin, Randall T ; Schurr, Michael J ; Sauer, Karin ; Lau, Gee W ; Sutton, Mark D ; Yu, Hongwei ; Høiby, Niels. / Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies. In: Expert Opinion On Therapeutic Targets. 2010 ; Vol. 14, No. 2. pp. 117-30.

Bibtex

@article{82baefe882ef45dcb683f43e112ae758,
title = "Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies",
abstract = "CF airway mucus can be infected by opportunistic microorganisms, notably Pseudomonas aeruginosa. Once organisms are established as biofilms, even the most potent antibiotics have little effect on their viability, especially during late-stage chronic infections. Better understanding of the mechanisms used by P. aeruginosa to circumvent host defenses and therapeutic intervention strategies is critical for advancing novel treatment strategies.",
keywords = "Biofilms, Cystic Fibrosis, Fimbriae, Bacterial, Flagella, Humans, Lung, Neutrophils, Pseudomonas Infections, Pseudomonas aeruginosa, Quorum Sensing, Sodium Nitrite",
author = "Hassett, {Daniel J} and Korfhagen, {Thomas R} and Irvin, {Randall T} and Schurr, {Michael J} and Karin Sauer and Lau, {Gee W} and Sutton, {Mark D} and Hongwei Yu and Niels H{\o}iby",
year = "2010",
month = feb,
day = "1",
doi = "10.1517/14728220903454988",
language = "English",
volume = "14",
pages = "117--30",
journal = "Expert Opinion on Therapeutic Targets",
issn = "1472-8222",
publisher = "Taylor & Francis",
number = "2",

}

RIS

TY - JOUR

T1 - Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies

AU - Hassett, Daniel J

AU - Korfhagen, Thomas R

AU - Irvin, Randall T

AU - Schurr, Michael J

AU - Sauer, Karin

AU - Lau, Gee W

AU - Sutton, Mark D

AU - Yu, Hongwei

AU - Høiby, Niels

PY - 2010/2/1

Y1 - 2010/2/1

N2 - CF airway mucus can be infected by opportunistic microorganisms, notably Pseudomonas aeruginosa. Once organisms are established as biofilms, even the most potent antibiotics have little effect on their viability, especially during late-stage chronic infections. Better understanding of the mechanisms used by P. aeruginosa to circumvent host defenses and therapeutic intervention strategies is critical for advancing novel treatment strategies.

AB - CF airway mucus can be infected by opportunistic microorganisms, notably Pseudomonas aeruginosa. Once organisms are established as biofilms, even the most potent antibiotics have little effect on their viability, especially during late-stage chronic infections. Better understanding of the mechanisms used by P. aeruginosa to circumvent host defenses and therapeutic intervention strategies is critical for advancing novel treatment strategies.

KW - Biofilms

KW - Cystic Fibrosis

KW - Fimbriae, Bacterial

KW - Flagella

KW - Humans

KW - Lung

KW - Neutrophils

KW - Pseudomonas Infections

KW - Pseudomonas aeruginosa

KW - Quorum Sensing

KW - Sodium Nitrite

U2 - 10.1517/14728220903454988

DO - 10.1517/14728220903454988

M3 - Journal article

C2 - 20055712

VL - 14

SP - 117

EP - 130

JO - Expert Opinion on Therapeutic Targets

JF - Expert Opinion on Therapeutic Targets

SN - 1472-8222

IS - 2

ER -

ID: 33918344