Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1. / Labbate, Maurizio; Queck, Shu Yeong; Koh, Kai Shyang; Rice, Scott A; Givskov, Michael; Kjelleberg, Staffan.

In: Journal of Bacteriology, Vol. 186, No. 3, 2004, p. 692-8.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Labbate, M, Queck, SY, Koh, KS, Rice, SA, Givskov, M & Kjelleberg, S 2004, 'Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1', Journal of Bacteriology, vol. 186, no. 3, pp. 692-8.

APA

Labbate, M., Queck, S. Y., Koh, K. S., Rice, S. A., Givskov, M., & Kjelleberg, S. (2004). Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1. Journal of Bacteriology, 186(3), 692-8.

Vancouver

Labbate M, Queck SY, Koh KS, Rice SA, Givskov M, Kjelleberg S. Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1. Journal of Bacteriology. 2004;186(3):692-8.

Author

Labbate, Maurizio ; Queck, Shu Yeong ; Koh, Kai Shyang ; Rice, Scott A ; Givskov, Michael ; Kjelleberg, Staffan. / Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1. In: Journal of Bacteriology. 2004 ; Vol. 186, No. 3. pp. 692-8.

Bibtex

@article{dd17a300fcef11ddb219000ea68e967b,
title = "Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1",
abstract = "Serratia liquefaciens MG1 contains an N-acylhomoserine lactone-mediated quorum-sensing system that is known to regulate swarming motility colonization. In this study, we describe for S. liquefaciens MG1 the development of a novel biofilm consisting of cell aggregates and differentiated cell types, such as cell chains and long filamentous cells. Furthermore, quorum sensing is shown to be crucial for normal biofilm development and for elaborate differentiation. A mutant of S. liquefaciens MG1 that was incapable of synthesizing extracellular signal formed a thin and nonmature biofilm lacking cell aggregates and differentiated cell chains. Signal-based complementation of this mutant resulted in a biofilm with the wild-type architecture. Two quorum-sensing-regulated genes (bsmA and bsmB) involved in biofilm development were identified, and we propose that these genes are engaged in fine-tuning the formation of cell aggregates at a specific point in biofilm development.",
author = "Maurizio Labbate and Queck, {Shu Yeong} and Koh, {Kai Shyang} and Rice, {Scott A} and Michael Givskov and Staffan Kjelleberg",
note = "Keywords: 4-Butyrolactone; Biofilms; Serratia liquefaciens",
year = "2004",
language = "English",
volume = "186",
pages = "692--8",
journal = "Journal of Bacteriology",
issn = "0021-9193",
publisher = "American Society for Microbiology",
number = "3",

}

RIS

TY - JOUR

T1 - Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1

AU - Labbate, Maurizio

AU - Queck, Shu Yeong

AU - Koh, Kai Shyang

AU - Rice, Scott A

AU - Givskov, Michael

AU - Kjelleberg, Staffan

N1 - Keywords: 4-Butyrolactone; Biofilms; Serratia liquefaciens

PY - 2004

Y1 - 2004

N2 - Serratia liquefaciens MG1 contains an N-acylhomoserine lactone-mediated quorum-sensing system that is known to regulate swarming motility colonization. In this study, we describe for S. liquefaciens MG1 the development of a novel biofilm consisting of cell aggregates and differentiated cell types, such as cell chains and long filamentous cells. Furthermore, quorum sensing is shown to be crucial for normal biofilm development and for elaborate differentiation. A mutant of S. liquefaciens MG1 that was incapable of synthesizing extracellular signal formed a thin and nonmature biofilm lacking cell aggregates and differentiated cell chains. Signal-based complementation of this mutant resulted in a biofilm with the wild-type architecture. Two quorum-sensing-regulated genes (bsmA and bsmB) involved in biofilm development were identified, and we propose that these genes are engaged in fine-tuning the formation of cell aggregates at a specific point in biofilm development.

AB - Serratia liquefaciens MG1 contains an N-acylhomoserine lactone-mediated quorum-sensing system that is known to regulate swarming motility colonization. In this study, we describe for S. liquefaciens MG1 the development of a novel biofilm consisting of cell aggregates and differentiated cell types, such as cell chains and long filamentous cells. Furthermore, quorum sensing is shown to be crucial for normal biofilm development and for elaborate differentiation. A mutant of S. liquefaciens MG1 that was incapable of synthesizing extracellular signal formed a thin and nonmature biofilm lacking cell aggregates and differentiated cell chains. Signal-based complementation of this mutant resulted in a biofilm with the wild-type architecture. Two quorum-sensing-regulated genes (bsmA and bsmB) involved in biofilm development were identified, and we propose that these genes are engaged in fine-tuning the formation of cell aggregates at a specific point in biofilm development.

M3 - Journal article

C2 - 14729694

VL - 186

SP - 692

EP - 698

JO - Journal of Bacteriology

JF - Journal of Bacteriology

SN - 0021-9193

IS - 3

ER -

ID: 10615170