Recurrence of bacteremia and infective endocarditis according to bacterial species of index endocarditis episode

Research output: Contribution to journal › Journal article › Research › peer-review

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Recurrence of bacteremia and infective endocarditis according to bacterial species of index endocarditis episode. / Østergaard, Lauge; Voldstedlund, Marianne; Bruun, Niels Eske; Bundgaard, Henning; Iversen, Kasper; Pries-Heje, Mia Marie; Hadji-Turdeghal, Katra; Graversen, Peter L.; Moser, Claus; Andersen, Christian Østergaard; Søgaard, Kirstine Kobberøe; Køber, Lars; Fosbøl, Emil Loldrup.

In: Infection, Vol. 51, 2023, p. 1739–1747.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Østergaard, L, Voldstedlund, M, Bruun, NE, Bundgaard, H, Iversen, K, Pries-Heje, MM, Hadji-Turdeghal, K, Graversen, PL, Moser, C, Andersen, CØ, Søgaard, KK, Køber, L & Fosbøl, EL 2023, 'Recurrence of bacteremia and infective endocarditis according to bacterial species of index endocarditis episode', Infection, vol. 51, pp. 1739–1747. https://doi.org/10.1007/s15010-023-02068-x

APA

Østergaard, L., Voldstedlund, M., Bruun, N. E., Bundgaard, H., Iversen, K., Pries-Heje, M. M., Hadji-Turdeghal, K., Graversen, P. L., Moser, C., Andersen, C. Ø., Søgaard, K. K., Køber, L., & Fosbøl, E. L. (2023). Recurrence of bacteremia and infective endocarditis according to bacterial species of index endocarditis episode. Infection, 51, 1739–1747. https://doi.org/10.1007/s15010-023-02068-x

Vancouver

Østergaard L, Voldstedlund M, Bruun NE, Bundgaard H, Iversen K, Pries-Heje MM et al. Recurrence of bacteremia and infective endocarditis according to bacterial species of index endocarditis episode. Infection. 2023;51:1739–1747. https://doi.org/10.1007/s15010-023-02068-x

Author

Østergaard, Lauge ; Voldstedlund, Marianne ; Bruun, Niels Eske ; Bundgaard, Henning ; Iversen, Kasper ; Pries-Heje, Mia Marie ; Hadji-Turdeghal, Katra ; Graversen, Peter L. ; Moser, Claus ; Andersen, Christian Østergaard ; Søgaard, Kirstine Kobberøe ; Køber, Lars ; Fosbøl, Emil Loldrup. / Recurrence of bacteremia and infective endocarditis according to bacterial species of index endocarditis episode. In: Infection. 2023 ; Vol. 51. pp. 1739–1747.

Bibtex

@article{6dcf3c3d47e9494f9404e04634c81717,
title = "Recurrence of bacteremia and infective endocarditis according to bacterial species of index endocarditis episode",
abstract = "Purpose: In patients surviving infective endocarditis (IE) recurrence of bacteremia or IE is feared. However, knowledge is sparse on the incidence and risk factors for the recurrence of bacteremia or IE. Methods: Using Danish nationwide registries (2010–2020), we identified patients with first-time IE which were categorized by bacterial species (Staphylococcus aureus, Enterococcus spp., Streptococcus spp., coagulase-negative staphylococci [CoNS], {\textquoteleft}Other{\textquoteright} microbiological etiology). Recurrence of bacteremia (including IE episodes) or IE with the same bacterial species was estimated at 12 months and 5 years, considering death as a competing risk. Cox regression models were used to compute adjusted hazard ratios of the recurrence of bacteremia or IE. Results: We identified 4086 patients with IE; 1374 (33.6%) with S. aureus, 813 (19.9%) with Enterococcus spp., 1366 (33.4%) with Streptococcus spp., 284 (7.0%) with CoNS, and 249 (6.1%) with {\textquoteleft}Other{\textquoteright}. The overall 12-month incidence of recurrent bacteremia with the same bacterial species was 4.8% and 2.6% with an accompanying IE diagnosis, while this was 7.7% and 4.0%, respectively, with 5 years of follow-up. S. aureus, Enterococcus spp., CoNS, chronic renal failure, and liver disease were associated with an increased rate of recurrent bacteremia or IE with the same bacterial species. Conclusion: Recurrent bacteremia with the same bacterial species within 12 months, occurred in almost 5% and 2.6% for recurrent IE. S. aureus, Enterococcus spp., and CoNS were associated with recurrent infections with the same bacterial species.",
keywords = "Bacteremia, Infective endocarditis, Recurrence, Reinfection, Relapse",
author = "Lauge {\O}stergaard and Marianne Voldstedlund and Bruun, {Niels Eske} and Henning Bundgaard and Kasper Iversen and Pries-Heje, {Mia Marie} and Katra Hadji-Turdeghal and Graversen, {Peter L.} and Claus Moser and Andersen, {Christian {\O}stergaard} and S{\o}gaard, {Kirstine Kobber{\o}e} and Lars K{\o}ber and Fosb{\o}l, {Emil Loldrup}",
note = "Publisher Copyright: {\textcopyright} 2023, The Author(s).",
year = "2023",
doi = "10.1007/s15010-023-02068-x",
language = "English",
volume = "51",
pages = "1739–1747",
journal = "Therapies",
issn = "0300-8126",
publisher = "Springer Medizin",

}

RIS

TY - JOUR

T1 - Recurrence of bacteremia and infective endocarditis according to bacterial species of index endocarditis episode

AU - Østergaard, Lauge

AU - Voldstedlund, Marianne

AU - Bruun, Niels Eske

AU - Bundgaard, Henning

AU - Iversen, Kasper

AU - Pries-Heje, Mia Marie

AU - Hadji-Turdeghal, Katra

AU - Graversen, Peter L.

AU - Moser, Claus

AU - Andersen, Christian Østergaard

AU - Søgaard, Kirstine Kobberøe

AU - Køber, Lars

AU - Fosbøl, Emil Loldrup

N1 - Publisher Copyright: © 2023, The Author(s).

PY - 2023

Y1 - 2023

N2 - Purpose: In patients surviving infective endocarditis (IE) recurrence of bacteremia or IE is feared. However, knowledge is sparse on the incidence and risk factors for the recurrence of bacteremia or IE. Methods: Using Danish nationwide registries (2010–2020), we identified patients with first-time IE which were categorized by bacterial species (Staphylococcus aureus, Enterococcus spp., Streptococcus spp., coagulase-negative staphylococci [CoNS], ‘Other’ microbiological etiology). Recurrence of bacteremia (including IE episodes) or IE with the same bacterial species was estimated at 12 months and 5 years, considering death as a competing risk. Cox regression models were used to compute adjusted hazard ratios of the recurrence of bacteremia or IE. Results: We identified 4086 patients with IE; 1374 (33.6%) with S. aureus, 813 (19.9%) with Enterococcus spp., 1366 (33.4%) with Streptococcus spp., 284 (7.0%) with CoNS, and 249 (6.1%) with ‘Other’. The overall 12-month incidence of recurrent bacteremia with the same bacterial species was 4.8% and 2.6% with an accompanying IE diagnosis, while this was 7.7% and 4.0%, respectively, with 5 years of follow-up. S. aureus, Enterococcus spp., CoNS, chronic renal failure, and liver disease were associated with an increased rate of recurrent bacteremia or IE with the same bacterial species. Conclusion: Recurrent bacteremia with the same bacterial species within 12 months, occurred in almost 5% and 2.6% for recurrent IE. S. aureus, Enterococcus spp., and CoNS were associated with recurrent infections with the same bacterial species.

AB - Purpose: In patients surviving infective endocarditis (IE) recurrence of bacteremia or IE is feared. However, knowledge is sparse on the incidence and risk factors for the recurrence of bacteremia or IE. Methods: Using Danish nationwide registries (2010–2020), we identified patients with first-time IE which were categorized by bacterial species (Staphylococcus aureus, Enterococcus spp., Streptococcus spp., coagulase-negative staphylococci [CoNS], ‘Other’ microbiological etiology). Recurrence of bacteremia (including IE episodes) or IE with the same bacterial species was estimated at 12 months and 5 years, considering death as a competing risk. Cox regression models were used to compute adjusted hazard ratios of the recurrence of bacteremia or IE. Results: We identified 4086 patients with IE; 1374 (33.6%) with S. aureus, 813 (19.9%) with Enterococcus spp., 1366 (33.4%) with Streptococcus spp., 284 (7.0%) with CoNS, and 249 (6.1%) with ‘Other’. The overall 12-month incidence of recurrent bacteremia with the same bacterial species was 4.8% and 2.6% with an accompanying IE diagnosis, while this was 7.7% and 4.0%, respectively, with 5 years of follow-up. S. aureus, Enterococcus spp., CoNS, chronic renal failure, and liver disease were associated with an increased rate of recurrent bacteremia or IE with the same bacterial species. Conclusion: Recurrent bacteremia with the same bacterial species within 12 months, occurred in almost 5% and 2.6% for recurrent IE. S. aureus, Enterococcus spp., and CoNS were associated with recurrent infections with the same bacterial species.

KW - Bacteremia

KW - Infective endocarditis

KW - Recurrence

KW - Reinfection

KW - Relapse

U2 - 10.1007/s15010-023-02068-x

DO - 10.1007/s15010-023-02068-x

M3 - Journal article

C2 - 37395924

AN - SCOPUS:85163856882

VL - 51

SP - 1739

EP - 1747

JO - Therapies

JF - Therapies

SN - 0300-8126

ER -

ID: 362696461