The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional

Research output: Contribution to journal › Journal article › Research › peer-review

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The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional. / Shrout, Joshua D; Chopp, David L; Just, Collin L; Hentzer, Morten; Givskov, Michael; Parsek, Matthew R.

In: Molecular Microbiology, Vol. 62, No. 5, 2006, p. 1264-77.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Shrout, JD, Chopp, DL, Just, CL, Hentzer, M, Givskov, M & Parsek, MR 2006, 'The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional', Molecular Microbiology, vol. 62, no. 5, pp. 1264-77. https://doi.org/10.1111/j.1365-2958.2006.05421.x

APA

Shrout, J. D., Chopp, D. L., Just, C. L., Hentzer, M., Givskov, M., & Parsek, M. R. (2006). The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional. Molecular Microbiology, 62(5), 1264-77. https://doi.org/10.1111/j.1365-2958.2006.05421.x

Vancouver

Shrout JD, Chopp DL, Just CL, Hentzer M, Givskov M, Parsek MR. The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional. Molecular Microbiology. 2006;62(5):1264-77. https://doi.org/10.1111/j.1365-2958.2006.05421.x

Author

Shrout, Joshua D ; Chopp, David L ; Just, Collin L ; Hentzer, Morten ; Givskov, Michael ; Parsek, Matthew R. / The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional. In: Molecular Microbiology. 2006 ; Vol. 62, No. 5. pp. 1264-77.

Bibtex

@article{bac5abd0fce511ddb219000ea68e967b,
title = "The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional",
abstract = "The role of quorum sensing in Pseudomonas aeruginosa biofilm formation is unclear. Some researchers have shown that quorum sensing is important for biofilm development, while others have indicated it has little or no role. In this study, the contribution of quorum sensing to biofilm development was found to depend upon the nutritional environment. Depending upon the carbon source, quorum-sensing mutant strains (lasIrhlI and lasRrhlR) either exhibited a pronounced defect early in biofilm formation or formed biofilms identical to the wild-type strain. Quorum sensing was then shown to exert its nutritionally conditional control of biofilm development through regulation of swarming motility. Examination of pilA and fliM mutant strains further supported the role of swarming motility in biofilm formation. These data led to a model proposing that the prevailing nutritional conditions dictate the contributions of quorum sensing and swarming motility at a key juncture early in biofilm development.",
author = "Shrout, {Joshua D} and Chopp, {David L} and Just, {Collin L} and Morten Hentzer and Michael Givskov and Parsek, {Matthew R}",
note = "Keywords: Biofilms; Food; Pseudomonas aeruginosa; Signal Transduction",
year = "2006",
doi = "10.1111/j.1365-2958.2006.05421.x",
language = "English",
volume = "62",
pages = "1264--77",
journal = "Molecular Microbiology",
issn = "0950-382X",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional

AU - Shrout, Joshua D

AU - Chopp, David L

AU - Just, Collin L

AU - Hentzer, Morten

AU - Givskov, Michael

AU - Parsek, Matthew R

N1 - Keywords: Biofilms; Food; Pseudomonas aeruginosa; Signal Transduction

PY - 2006

Y1 - 2006

N2 - The role of quorum sensing in Pseudomonas aeruginosa biofilm formation is unclear. Some researchers have shown that quorum sensing is important for biofilm development, while others have indicated it has little or no role. In this study, the contribution of quorum sensing to biofilm development was found to depend upon the nutritional environment. Depending upon the carbon source, quorum-sensing mutant strains (lasIrhlI and lasRrhlR) either exhibited a pronounced defect early in biofilm formation or formed biofilms identical to the wild-type strain. Quorum sensing was then shown to exert its nutritionally conditional control of biofilm development through regulation of swarming motility. Examination of pilA and fliM mutant strains further supported the role of swarming motility in biofilm formation. These data led to a model proposing that the prevailing nutritional conditions dictate the contributions of quorum sensing and swarming motility at a key juncture early in biofilm development.

AB - The role of quorum sensing in Pseudomonas aeruginosa biofilm formation is unclear. Some researchers have shown that quorum sensing is important for biofilm development, while others have indicated it has little or no role. In this study, the contribution of quorum sensing to biofilm development was found to depend upon the nutritional environment. Depending upon the carbon source, quorum-sensing mutant strains (lasIrhlI and lasRrhlR) either exhibited a pronounced defect early in biofilm formation or formed biofilms identical to the wild-type strain. Quorum sensing was then shown to exert its nutritionally conditional control of biofilm development through regulation of swarming motility. Examination of pilA and fliM mutant strains further supported the role of swarming motility in biofilm formation. These data led to a model proposing that the prevailing nutritional conditions dictate the contributions of quorum sensing and swarming motility at a key juncture early in biofilm development.

U2 - 10.1111/j.1365-2958.2006.05421.x

DO - 10.1111/j.1365-2958.2006.05421.x

M3 - Journal article

C2 - 17059568

VL - 62

SP - 1264

EP - 1277

JO - Molecular Microbiology

JF - Molecular Microbiology

SN - 0950-382X

IS - 5

ER -

ID: 10613706