Tolerance and resistance of microbial biofilms

Research output: Contribution to journal › Review › Research › peer-review

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Tolerance and resistance of microbial biofilms. / Ciofu, Oana; Moser, Claus; Jensen, Peter Østrup; Høiby, Niels.

In: Nature Reviews Microbiology, Vol. 20, 2022, p. 621–635.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Ciofu, O, Moser, C, Jensen, PØ & Høiby, N 2022, 'Tolerance and resistance of microbial biofilms', Nature Reviews Microbiology, vol. 20, pp. 621–635. https://doi.org/10.1038/s41579-022-00682-4

APA

Ciofu, O., Moser, C., Jensen, P. Ø., & Høiby, N. (2022). Tolerance and resistance of microbial biofilms. Nature Reviews Microbiology, 20, 621–635. https://doi.org/10.1038/s41579-022-00682-4

Vancouver

Ciofu O, Moser C, Jensen PØ, Høiby N. Tolerance and resistance of microbial biofilms. Nature Reviews Microbiology. 2022;20:621–635. https://doi.org/10.1038/s41579-022-00682-4

Author

Ciofu, Oana ; Moser, Claus ; Jensen, Peter Østrup ; Høiby, Niels. / Tolerance and resistance of microbial biofilms. In: Nature Reviews Microbiology. 2022 ; Vol. 20. pp. 621–635.

Bibtex

@article{75d2104bbe374d58967ec38c71c60596,
title = "Tolerance and resistance of microbial biofilms",
abstract = "Chronic infections caused by microbial biofilms represent an important clinical challenge. The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major cause of persistence and clinical recurrence of these infections. In this Review, we present the extent of the clinical problem, and the mechanisms underlying the tolerance of biofilms to antibiotics and to host responses. We also explore the role of biofilms in the development of antimicrobial resistance mechanisms.",
author = "Oana Ciofu and Claus Moser and Jensen, {Peter {\O}strup} and Niels H{\o}iby",
note = "Publisher Copyright: {\textcopyright} 2022, Springer Nature Limited.",
year = "2022",
doi = "10.1038/s41579-022-00682-4",
language = "English",
volume = "20",
pages = "621–635",
journal = "Nature Reviews. Microbiology",
issn = "1740-1526",
publisher = "nature publishing group",

}

RIS

TY - JOUR

T1 - Tolerance and resistance of microbial biofilms

AU - Ciofu, Oana

AU - Moser, Claus

AU - Jensen, Peter Østrup

AU - Høiby, Niels

N1 - Publisher Copyright: © 2022, Springer Nature Limited.

PY - 2022

Y1 - 2022

N2 - Chronic infections caused by microbial biofilms represent an important clinical challenge. The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major cause of persistence and clinical recurrence of these infections. In this Review, we present the extent of the clinical problem, and the mechanisms underlying the tolerance of biofilms to antibiotics and to host responses. We also explore the role of biofilms in the development of antimicrobial resistance mechanisms.

AB - Chronic infections caused by microbial biofilms represent an important clinical challenge. The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major cause of persistence and clinical recurrence of these infections. In this Review, we present the extent of the clinical problem, and the mechanisms underlying the tolerance of biofilms to antibiotics and to host responses. We also explore the role of biofilms in the development of antimicrobial resistance mechanisms.

U2 - 10.1038/s41579-022-00682-4

DO - 10.1038/s41579-022-00682-4

M3 - Review

C2 - 35115704

AN - SCOPUS:85124136975

VL - 20

SP - 621

EP - 635

JO - Nature Reviews. Microbiology

JF - Nature Reviews. Microbiology

SN - 1740-1526

ER -

ID: 292089721