Niels Høiby

Niels Høiby

Professor, No job title

Member of:

    ORCID: 0000-0002-1347-725X

    Publication year:
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    351 - 400 out of 508Page size: 50
    1. 2012
    2. Published

      Pathology and biofilm formation in a porcine model of staphylococcal osteomyelitis

      Johansen, L. K., Koch, J., Frees, Dorte, Aalbæk, Bent, Nielsen, O. L., Leifsson, Páll S., Iburg, T. M., Svalastoga, Eiliv Lars, Buelund, Lene Elisabeth, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Henrik Elvang, 2012, In: Journal of Comparative Pathology. 147, 2-3, p. 343-353 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa

      Marvig, R. L., Søndergaard, M. S. R., Damkiær, S., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., Aug 2012, In: Antimicrobial Agents and Chemotherapy. 56, 8, p. 4519-4521 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      PmrB Mutations Promote Polymyxin Resistance of Pseudomonas aeruginosa Isolated from Colistin-Treated Cystic Fibrosis Patients

      Moskowitz, S. M., Brannon, M. K., Dasgupta, N., Pier, M., Sgambati, N., Miller, A. K., Selgrade, S. E., Miller, S. I., Denton, M., Conway, S. P., Johansen, Helle Krogh & Høiby, Niels, Feb 2012, In: Antimicrobial Agents and Chemotherapy. 56, 2, p. 1019-1030 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production

      Sautter, R., Ramos, D., Schneper, L., Ciofu, Oana, Wassermann, T., Koh, C., Heydorn, A., Hentzer, M., Høiby, Niels, Kharazmi, A., Molin, S., Devries, C. A., Ohman, D. E. & Mathee, K., 1 May 2012, In: Gene. 498, 2, p. 242-253 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Culture-dependent and -independent investigations of microbial diversity on urinary catheters

      Xu, Y., Moser, Claus Ernst, Abu Al-Soud, W., Sørensen, Søren Johannes, Høiby, Niels, Nielsen, P. H. & Thomsen, T. R., 2012, In: Journal of Clinical Microbiology. 50, 12, p. 3901-3908 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Combating biofilms

      Yang, L., Liu, Y., Wu, H., Song, Z., Høiby, Niels, Molin, S. & Givskov, Michael, 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 146–157

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Polysaccharides serve as scaffold of biofilms formed by mucoid Pseudomonas aeruginosa

      Yang, L., Hengzhuang, W., Wu, H., Damkiaer, S., Jochumsen, N., Song, Z., Givskov, Michael, Høiby, Niels & Molin, S., Jul 2012, In: F E M S Immunology and Medical Microbiology. 65, 2, p. 366-376 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo

      van Gennip, M., Hultqvist, Louise Dahl, Alhede, M., Qvortrup, Klaus, Jensen, Peter Østrup, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, Aug 2012, In: Infection and Immunity. 80, 8, p. 2601-2607 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. 2013
    11. Published

      Clinical effects of sinus surgery and adjuvant therapy in cystic fibrosis patients - can chronic lung infections be postponed?

      Aanæs, Kasper, Johansen, Helle Krogh, Skov, M., Buchvald, F. F., Hjuler, Thomas, Pressler, T., Høiby, Niels, Nielsen, Kim G. & von Buchwald, Christian, 2013, In: Rhinology. 51, 3, p. 222-230 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Applying insights from biofilm biology to drug development - can a new approach be developed?

      Bjarnsholt, Thomas, Ciofu, Oana, Molin, S., Givskov, Michael & Høiby, Niels, 1 Oct 2013, In: Nature Reviews. Drug Discovery. 12, 10, p. 791-808 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      The in vivo biofilm

      Bjarnsholt, Thomas, Alhede, M., Alhede, M., Eickhardt-Sørensen, S. R., Moser, Claus Ernst, Kühl, Michael, Jensen, Peter Østrup & Høiby, Niels, 2013, In: Trends in Microbiology. 21, 9, p. 466-474 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    14. Published

      Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms

      Chiang, W., Nilsson, M., Jensen, Peter Østrup, Høiby, Niels, Nielsen, T., Givskov, Michael & Tolker-Nielsen, Tim, May 2013, In: Antimicrobial Agents and Chemotherapy. 57, 5, p. 2352-61 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      P. aeruginosa in the paranasal sinuses and transplanted lungs have similar adaptive mutations as isolates from chronically infected CF lungs

      Ciofu, Oana, Johansen, Helle Krogh, Aanæs, Kasper, Wassermann, T., Alhede, M., von Buchwald, Christian & Høiby, Niels, 8 Mar 2013, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 12, 6, p. 729-736 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Respiratory bacterial infections in cystic fibrosis

      Ciofu, Oana, Hansen, C. R. & Høiby, Niels, May 2013, In: Current Opinion in Pulmonary Medicine. 19, 3, p. 251-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      A cohort study of the Copenhagen CF Centre eradication strategy against Staphylococcus aureus in patients with CF

      Dalbøge, C. S., Pressler, T., Høiby, Niels, Nielsen, Kim G. & Johansen, Helle Krogh, Jan 2013, In: Journal of Cystic Fibrosis. 12, 1, p. 42-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      A non-fatal case of invasive zygomycete (Lichtheimia corymbifera) infection in an allogeneic haematopoietic cell transplant recipient

      Eickhardt, S., Braendstrup, P., Clasen-Linde, E., Jensen, K. E., Alhede, M., Bjarnsholt, Thomas, Høiby, Niels, Vindeløv, L. & Moser, Claus Ernst, May 2013, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 121, 5, p. 456-9 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      High β-lactamase levels change the pharmacodynamics of β-lactam antibiotics in Pseudomonas aeruginosa biofilms

      Hengzhuang, W., Ciofu, Oana, Yang, L., Wu, H., Song, Z., Oliver, A. & Høiby, Niels, Jan 2013, In: Antimicrobial Agents and Chemotherapy. 57, 1, p. 196-204 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Clearance of Pseudomonas aeruginosa Foreign-Body Biofilm Infections through Reduction of the Cyclic Di-GMP Level in the Bacteria

      Hultqvist, Louise Dahl, van Gennip, M., Rybtke, Morten Levin, Wu, H., Chiang, W., Alhede, M., Høiby, Niels, Nielsen, T., Givskov, Michael & Tolker-Nielsen, Tim, Aug 2013, In: Infection and Immunity. 81, 8, p. 2705-13 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes

      Jakobsen, T. H., Hansen, M. A., Jensen, P. Ø., Hansen, L., Riber, L., Cockburn, A. P. I., Kolpen, M., Hansen, C. R., Ridderberg, W., Eickhardt-Sørensen, S. R., Hansen, M., Kerpedjiev, P., Alhede, M., Qvortrup, K., Burmølle, M., Moser, C. E., Kühl, M., Ciofu, O., Givskov, M., Sørensen, S. J. & 2 others, Høiby, Niels & Bjarnsholt, Thomas, 2013, In: P L o S One. 8, 7, 17 p., e68484.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors

      Jakobsen, Tim Holm, Bjarnsholt, Thomas, Jensen, Peter Østrup, Givskov, Michael & Høiby, Niels, Jul 2013, In: Future Microbiology. 8, 7, p. 901-21 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Sublethal ciprofloxacin treatment leads to rapid development of high-level ciprofloxacin resistance during long-term experimental evolution of Pseudomonas aeruginosa

      Jørgensen, K. M., Wassermann, T., Jensen, Peter Østrup, Hengzuang, W., Molin, S., Høiby, Niels & Ciofu, Oana, Sep 2013, In: Antimicrobial Agents and Chemotherapy. 57, 9, p. 4215-21 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Dietzia papillomatosis Bacteremia

      Rammer, P., Calum, Henrik Pierre, Moser, Claus Ernst, Björnsdóttir, M. K., Smedegaard, H., Høiby, Niels & Bjarnsholt, Thomas, Jun 2013, In: Journal of Clinical Microbiology. 51, 6, p. 1977-8 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Effect of infectious dose and season on development of hemorrhagic pneumonia in mink caused by Pseudomonas aeruginosa

      Salomonsen, C. M., Chriél, M., Jensen, T. H., Rangstrup-Christensen, L., Høiby, Niels & Hammer, Anne Sofie Vedsted, 2013, In: Canadian Journal of Veterinary Research. 77, 3, p. 221-225 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Typing of Pseudomonas aeruginosa from hemorrhagic pneumonia in mink (Neovison vison)

      Salomonsen, C. M., Themudo, G. E., Jelsbak, L., Molin, S., Høiby, Niels & Hammer, Anne Sofie Vedsted, 2013, In: Veterinary Microbiology. 163, 1-2, p. 103-109 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Prosthesis infections after orthopedic joint replacement: the possible role of bacterial biofilms

      Song, Z., Borgwardt, L., Høiby, Niels, Wu, H., Sørensen, T. S. & Borgwardt, A., 7 Jun 2013, In: Orthopedic Reviews. 5, 2, p. 65-71 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Comparative genomic analysis of rapid evolution of an extreme-drug- resistant Acinetobacter baumannii clone

      Tan, S., Chua, S. L., Liu, Y., Høiby, Niels, Andersen, L. P., Givskov, Michael, Song, Z. & Yang, L., 2013, In: Genome Biology and Evolution. p. 807–818

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Pseudomonas aeruginosa biofilm aggravates skin inflammatory response in BALB/c mice in a novel chronic wound model

      Trøstrup, H., Thomsen, K., Christophersen, L. J., Hougen, H. P., Bjarnsholt, Thomas, Jensen, Peter Østrup, Kirkby, N., Calum, H., Høiby, Niels & Moser, Claus Ernst, Mar 2013, In: Wound Repair and Regeneration. 21, 2, p. 292-299 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Direct sequencing and RipSeq interpretation as a tool for identification of polymicrobial infections

      Wolff, T. Y., Eickhardt, S., Björnsdottir, M. K., Moser, Claus Ernst, Bjarnsholt, Thomas, Høiby, Niels & Thomsen, T. R., Apr 2013, In: Journal of Clinical Microbiology. 51, 4, p. 1281-4 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. 2014
    32. Published

      Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?

      Aanæs, Kasper, Eickhardt, S., Johansen, Helle Krogh, von Buchwald, Christian, Skov, M., Høiby, Niels & Bjarnsholt, Thomas, 2014, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. p. 1-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Bacterial biofilm formation and treatment in soft tissue fillers

      Alhede, M., Er, O., Eickhardt, S., Kragh, K., Alhede, M., Hultqvist, Louise Dahl, Poulsen, Steen Seier, Givskov, Michael, Christensen, L. H., Høiby, Niels, Tvede, M. & Bjarnsholt, Thomas, 30 Jan 2014, In: Pathogens and Disease. 70, p. 339-346 8 p.

      Research output: Contribution to journal › Journal article › Research

    34. Published

      Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation

      Brochmann, R. P., Toft, A., Ciofu, Oana, Briales, A., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Jensen, Peter Østrup, 2014, In: International Journal of Antimicrobial Agents. 43, 2, p. 140-147 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis

      Dalbøge, C. S., Nielsen, X. C., Dalhoff, K., Alffenaar, J. W., Duno, M., Buchard, Anders, Uges, D. R. A., Jensen, A. G., Jürgens, G., Pressler, T., Johansen, H. K. & Høiby, Niels, Mar 2014, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 13, 2, p. 179-85 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      PNA-based fluorescence in situ hybridization for identification of bacteria in clinical samples

      Fazli, M., Bjarnsholt, Thomas, Høiby, Niels, Givskov, Michael & Tolker-Nielsen, Tim, 2014, In: Methods in Molecular Biology. 1211, p. 261-71 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Pharmacokinetics and pharmacodynamics of antibiotics in biofilm infections of Pseudomonas aeruginosa in vitro and in vivo

      Hengzhuang, W., Høiby, Niels & Ciofu, Oana, 2014, In: Methods in molecular biology (Clifton, N.J.). 1147, p. 239-54 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      A personal history of research on microbial biofilms and biofilm infections

      Høiby, Niels, Apr 2014, In: Pathogens and Disease. 70, 3, p. 205-211 7 p.

      Research output: Contribution to journal › Review › Research › peer-review

    39. Published

      Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms

      Jensen, Peter Østrup, Briales, A., Brochmann, R. P., Wang, H., Kragh, K. N., Kolpen, Mette, Hempel, C., Bjarnsholt, Thomas, Høiby, Niels & Ciofu, Oana, 2014, In: Pathogens and Disease. 70, 3, p. 440-443 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Rapid identification of Stenotrophomonas maltophilia by peptide nucleic acid fluorescence in situ hybridization

      Knudsen, N. R., Rasmussen, A. K. I., Fiandaca, M. J., Kragh, K. N., Bjarnsholt, Thomas, Høiby, Niels, Stender, H. & Guardabassi, Luca, 2014, In: New Microbes and New Infections. 2, 3, p. 79-81 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Nitric oxide production by polymorphonuclear leukocytes in infected cystic fibrosis sputum consumes oxygen

      Kolpen, Mette, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Rickelt, L. F., Kühl, Michael, Hempel, C., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Clinical and Experimental Immunology. 177, 1, p. 310–319 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection

      Kolpen, Mette, Kühl, Michael, Bjarnsholt, Thomas, Moser, Claus Ernst, Hansen, C. R., Liengaard, L., Kharazmi, A., Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2014, In: PLOS ONE. 9, 1, p. e84353 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Polymorphonuclear leukocytes restrict growth of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients

      Kragh, K. N., Alhede, M., Jensen, Peter Østrup, Moser, Claus Ernst, Scheike, Thomas, Jacobsen, C. S., Poulsen, Steen Seier, Eickhardt-Sørensen, S. R., Trostrup, H., Christoffersen, L., Hougen, H. P., Rickelt, L. F., Kühl, Michael, Høiby, Niels & Bjarnsholt, Thomas, 2014, In: Infection and Immunity. 82, 11, p. 4477-4486 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum

      Line, L., Alhede, M., Kolpen, Mette, Kühl, Michael, Ciofu, Oana, Bjarnsholt, Thomas, Moser, Claus Ernst, Toyofuku, M., Nomura, N., Høiby, Niels & Jensen, Peter Østrup, 2014, In: Frontiers in Microbiology. 5, 11 p., 554.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Environmental Heterogeneity Drives Within-Host Diversification and Evolution of Pseudomonas aeruginosa

      Markussen, T., Marvig, R. L., Gómez-Lozano, M., Aanæs, K., Burleigh, A. E., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., 2014, In: mBio. 5, 5, p. 1-10 10 p., e01592-14.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Staphylococcus aureus alters growth activity, autolysis and antibiotic tolerance in a human host-adapted Pseudomonas aeruginosa lineage

      Michelsen, C. F., Christensen, A. J., Bojer, Martin Saxtorph, Høiby, Niels, Ingmer, Hanne & Jelsbak, L., 2014, In: Journal of Bacteriology. 196, 22, p. 3903-3911 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      A mariner transposon vector adapted for mutagenesis in oral streptococci

      Nilsson, M., Christiansen, N., Høiby, Niels, Twetman, Svante, Givskov, Michael & Tolker-Nielsen, Tim, Jun 2014, In: MicrobiologyOpen. 3, 3, p. 333-40 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Shifting paradigms of nontuberculous mycobacteria in cystic fibrosis

      Qvist, T., Pressler, T., Høiby, Niels & Katzenstein, T. L., 2014, In: Respiratory research. 15, p. 1-6 6 p., 41.

      Research output: Contribution to journal › Comment/debate › Research

    49. Published

      Urine lipoarabinomannan point-of-care testing in patients affected by pulmonary nontuberculous mycobacteria - experiences from the Danish Cystic Fibrosis cohort study

      Qvist, T., Johansen, I. S., Pressler, T., Høiby, Niels, Andersen, A. B., Katzenstein, T. L. & Bjerrum, S., 4 Dec 2014, In: BMC Infectious Diseases. 14, p. 1-8 8 p., 655.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Effects of Radix Ginseng on microbial infections: a narrative review

      Wu, H., Høiby, Niels, Yang, L., Givskov, Michael & Song, Z., Apr 2014, In: Journal of Traditional Chinese Medicine. 34, 2, p. 227-233 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. 2015
    52. Published

      A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia

      Alanin, M. C., Nielsen, K. G., von Buchwald, Christian, Skov, M., Aanæs, Kasper, Høiby, Niels & Johansen, Helle Krogh, Dec 2015, In: Clinical Microbiology and Infection. 21, 12, p. 1093.e1–1093.e7 7 p., 1093.e.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia

      Alanin, M. C., Johansen, Helle Krogh, Aanaes, K., Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G. & von Buchwald, Christian, Jan 2015, In: Acta Oto-Laryngologica. 135, 1, p. 58-63 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Antibiofilm Properties of Acetic Acid

      Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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