Thomas Eiland Nielsen
Affiliate Professor
Bacteriology
Nørre Allé 14
2200 København N
- 2011
- Published
A convenient procedure for the solid-phase synthesis of hydroxamic acids on PEGA resins
Nandurkar, N. S., Petersen, R., Qvortrup, K., Komnatnyy, V. V., Taveras, K. M., Le Quement, S. T., Frauenlob, R., Givskov, Michael & Nielsen, Thomas Eiland, 28 Dec 2011, In: Tetrahedron Letters. 52, 52, p. 7121-7124 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Identification of five structurally unrelated quorum-sensing inhibitors of Pseudomonas aeruginosa from a natural-derivative database
Tan, S. Y. Y., Chua, S. L., Chen, Y., Rice, S. A., Kjelleberg, S., Nielsen, Thomas Eiland, Yang, L. & Givskov, Michael, Nov 2013, In: Antimicrobial Agents and Chemotherapy. 57, 11, p. 5629-5641 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Synthesis of 4-halogenated 3-fluoro-6-methoxyquinolines: Key building blocks for the synthesis of antibiotics
Flagstad, T., Petersen, M. T., Hinnerfeldt, D. M., Givskov, Michael & Nielsen, Thomas Eiland, 28 Aug 2014, In: Synthesis (Germany). 46, 23, p. 3263-3267 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
In vitro and in vivo generation and characterization of Pseudomonas aeruginosa biofilm-dispersed cells via c-di-GMP manipulation
Chua, S. L., Hultqvist, Louise Dahl, Yuan, M., Rybtke, Morten Levin, Nielsen, Thomas Eiland, Givskov, Michael, Tolker-Nielsen, Tim & Yang, L., Aug 2015, In: Nature Protocols (Print). 10, 8, p. 1165-80 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
The anti-cancerous drug doxorubicin decreases the c-di-GMP content in Pseudomonas aeruginosa but promotes biofilm formation
Groizeleau, J., Rybtke, Morten Levin, Andersen, Jens Bo, Berthelsen, J., Liu, Y., Yang, L., Nielsen, Thomas Eiland, Kaever, V., Givskov, Michael & Tolker-Nielsen, Tim, 1 Oct 2016, In: Microbiology. 162, 10, p. 1797-1807 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
A broad range quorum sensing inhibitor working through sRNA inhibition
Jakobsen, Tim Holm, Warming, A. N., Vejborg, R. M., Moscoso, J. A., Stegger, M., Lorenzen, F., Rybtke, Morten Levin, Andersen, Jens Bo, Petersen, R., Andersen, P. S., Nielsen, Thomas Eiland, Tolker-Nielsen, Tim, Filloux, A., Ingmer, Hanne & Givskov, Michael, 2017, In: Scientific Reports. 7, 1, 12 p., 9857.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists
Palmer, D., Gonçalves, J. P. L., Hansen, L. V., Wu, B., Hald, H., Schoffelen, S., Diness, Frederik, Le Quement, S. T., Nielsen, Thomas Eiland & Meldal, Morten Peter, 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 8716-8730 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diastereoselective synthesis of novel heterocyclic scaffolds through tandem Petasis 3-component/intramolecular Diels-Alder and ROM-RCM reactions
Ishoey, M., Petersen, R. G., Petersen, M. A., Wu, P., Clausen, M. H. & Nielsen, Thomas Eiland, 2017, In: Chemical Communications. 53, 68, p. 9410-9413Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinase Inhibitors
Wu, P., Givskov, Michael & Nielsen, Thomas Eiland, 2017, Drug Selectivity: An Evolving Concept in Medicinal Chemistry. Wiley-Interscience, p. 33-53 21 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Scaffold Diversity from N-Acyliminium Ions
Wu, P. & Nielsen, Thomas Eiland, 2017, In: Chemical Reviews. 117, 12, p. 7811-7856 46 p.Research output: Contribution to journal › Review › Research › peer-review
ID: 162434453
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A broad range quorum sensing inhibitor working through sRNA inhibition
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
198
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Small Molecule Anti-biofilm Agents Developed on the Basis of Mechanistic Understanding of Biofilm Formation
Research output: Contribution to journal › Review › Research › peer-review
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162
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Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa
Research output: Contribution to journal › Journal article › Research › peer-review
Published