Tim Tolker-Nielsen

Tim Tolker-Nielsen

Professor

Member of:


    1. Published

      Erratum for Almblad et al., The Cyclic AMP-Vfr Signaling Pathway in Pseudomonas aeruginosa Is Inhibited by Cyclic Di-GMP

      Almblad, H., Harrison, J. J., Rybtke, Morten Levin, Groizeleau, J., Givskov, Michael, Parsek, M. R. & Tolker-Nielsen, Tim, Aug 2015, In: Journal of Bacteriology. 197, 16, p. 2731 1 p.

      Research output: Contribution to journalComment/debateResearch

    2. Published

      Erratum: Fluctuation analysis of mutations to nalidixic acid resistance in Escherichia coli (Journal of Bacteriology 176:10 (2785))

      Boe, L., Tolker-Nielsen, Tim, Eegholm, K. M., Spliid, H. & Vrang, A., 1 Jan 1994, In: Journal of Bacteriology. 176, 14, 1 p.

      Research output: Contribution to journalComment/debateResearchpeer-review

    3. Published

      Engineering PQS biosynthesis pathway for enhancement of bioelectricity production in Pseudomonas aeruginosa microbial fuel cells

      Wang, V. B., Chua, S., Cao, B., Seviour, T., Nesatyy, V. J., Marsili, E., Kjelleberg, S., Givskov, Michael, Tolker-Nielsen, Tim, Song, H., Loo, J. S. C. & Yang, L., 2013, In: PLOS ONE. 8, 5, p. e63129 7 p., e63129.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Elevated c-di-GMP Levels and Expression of the Type III Secretion System Promote Corneal Infection by Pseudomonas aeruginosa

      Yam, J. K. H., Aung, T. T., Chua, S. L., Cheng, Y., Kohli, G. S., Zhou, J., Constancias, F., Liu, Y., Cai, Z., Salido, M. M. S., Drautz-Moses, D. I., Rice, S. A., Schuster, S. C., Boo, Z. Z., Wu, B., Kjelleberg, S., Tolker-Nielsen, T., Lakshminarayanan, R., Beuerman, R. W., Yang, L. & 1 others, Givskov, Michael, 2022, In: Infection and Immunity. 90, 8

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Effects of stress treatments on the detection of Salmonella typhimurium by in situ hybridization.

      Tolker-Nielsen, Tim, Larsen, M. H., Kyed, H. & Molin, S., 1997, In: International Journal of Food Microbiology. 35, 3, p. 251-8 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Effects of iron on DNA release and biofilm development by Pseudomonas aeruginosa.

      Yang, L., Barken, K. B., Skindersoe, M. E., Christensen, A. B., Givskov, M. & Tolker-Nielsen, Tim, 2007, In: Microbiology. 153, Pt 5, p. 1318-28 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa

      Skindersoe, M. E., Alhede, M., Phipps, R., Yang, L., Jensen, P. O., Rasmussen, T. B., Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Høiby, Niels & Givskov, Michael, 1 Oct 2008, In: Antimicrobial Agents and Chemotherapy. 52, 10, p. 3648-63 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Effects of antibiotic treatment and phagocyte infiltration on development of Pseudomonas aeruginosa biofilm—Insights from the application of a novel PF hydrogel model in vitro and in vivo

      Wu, H., Song, L., Yam, J. K. H., Plotkin, M., Wang, H., Rybtke, Morten Levin, Seliktar, D., Kofidis, T., Høiby, Niels, Tolker-Nielsen, Tim, Song, Z. & Givskov, Michael, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 826450.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Dynamics of development and dispersal in sessile microbial communities: examples from Pseudomonas aeruginosa and Pseudomonas putida model biofilms.

      Klausen, M., Gjermansen, M., Kreft, J. & Tolker-Nielsen, Tim, 2006, In: FEMS Microbiology Letters. 261, 1, p. 1-11 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Draft Genome Sequence of the Model Naphthalene-Utilizing Organism Pseudomonas putida OUS82

      Tay, M., Roizman, D., Cohen, Y., Tolker-Nielsen, Tim, Givskov, Michael & Yang, L., 2014, In: Genome Announcements. 2, 1, p. 1 1 p., e01161-13.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Distribution, organization, and ecology of bacteria in chronic wounds

      Kirketerp-Møller, K., Jensen, Peter Østrup, Fazli, M., Madsen, K. G., Pedersen, J., Moser, C., Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael & Bjarnsholt, Thomas, 1 Aug 2008, In: Journal of Clinical Microbiology. 46, 8, p. 2717-22 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through lack of the Rieske cytochrome bc1sub-unit

      Soh, E. Y. C., Smith, F., Gimenez, M. R., Yang, L., Vejborg, R. M., Fletcher, M., Halliday, N., Bleves, S., Heeb, S., Cámara, M., Givskov, Michael, Hardie, K. R., Tolker-Nielsen, Tim, Ize, B. & Williams, P., 2021, In: PLOS Pathogens. 17, 8, 25 p., e1009425.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through loss of the Rieske cytochrome bc1 sub-unit

      Soh, E., Smith, F., Gimenez, M. R., Yang, L., Vejborg, R. M., Fletcher, M., Halliday, N., Bleves, S., Heeb, S., Camara, M., Givskov, Michael, Hardie, K. R., Tolker-Nielsen, Tim, Ize, B. & Williams, P., 2021, bioRxiv, 43 p.

      Research output: Working paperPreprint

    14. Published

      Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles

      Chua, S. L., Liu, Y., Yam, J. K. H., Chen, Y., Vejborg, R. M., Tan, B. G. C., Kjelleberg, S., Tolker-Nielsen, Tim, Givskov, Michael & Yang, L., 2014, In: Nature Communications. 5, p. 1-12 13 p., 4462.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Differentiation and distribution of colistin- and sodium dodecyl sulfate-tolerant cells in Pseudomonas aeruginosa biofilms.

      Haagensen, J. A. J., Klausen, M., Ernst, R. K., Miller, S. I., Folkesson, A., Tolker-Nielsen, Tim & Molin, S., 2006, In: Journal of Bacteriology. 189, 1, p. 28-37 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Development and dynamics of Pseudomonas sp. biofilms.

      Tolker-Nielsen, Tim, Brinch, U. C., Ragas, P. C., Andersen, J. B., Jacobsen, C. S. & Molin, S., 2000, In: Journal of Bacteriology. 182, 22, p. 6482-9 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Detection of Bacteria by Fluorescence in Situ Hybridization in Culture-Negative Soft Tissue Filler Lesions

      Bjarnsholt, Thomas, Tolker-Nielsen, Tim, Givskov, Michael, Janssen, M. & Christensen, L. H., 2009, In: Dermatologic Surgery. 35 Suppl 2, p. 1620-1624 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. DNase1L2 suppresses biofilm formation by Pseudomonas aeruginosa and Staphylococcus aureus.

      Eckhart, L., Fischer, H., Barken, K. B., Tolker-Nielsen, Tim & Tschachler, E., 2007, In: British Journal of Dermatology. 156, 6, p. 1342-5 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Cyclic-di-GMP signaling controls metabolic activity in Pseudomonas aeruginosa

      Lichtenberg, Mads, Kragh, K. N., Fritz, Blaine Gabriel, Kirkegaard, Julius Bier, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2022, In: Cell Reports. 41, 3, p. 111515 1 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Cyclic-di-GMP is required for corneal infection by Pseudomonas aeruginosa and modulates host immunity

      Hoong Yam, J. K., Aung, T. T., Chua, S. L., Cheng, Y., Kohli, G. S., Zhou, J., Constancias, F., Liu, Y., Cai, Z., Santillan Salido, M. M., Drautz-Moses, D. I., Rice, S. A., Schuster, S. C., Wu, B., Kjelleberg, S., Tolker-Nielsen, Tim, Beuerman, R. W., Givskov, Michael & Yang, L., 2017, bioRxiv, 35 p.

      Research output: Working paperPreprint

    21. Crystal ball: leading scientists in the field of environmental microbiology consider the technical and conceptual developments that they believe will drive innovative research during the first years of the new millennium.

      Caldwell, D. E., Colwell, R. R., Harayama, S., Kjelleberg, S., Givskov, M., Molin, S., Nielsen, A. T., Heydorn, A., Tolker-Nielsen, Tim, Sternberg, C., Nealson, K., Pace, N. R., Rainey, P., Stackebrandt, E., Tindall, B. J. & Stahl, D. A., 2000, In: Environmental Microbiology. 2, 1, p. 3-10 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Cranberry (Vaccinium macrocarpon) oligosaccharides decrease biofilm formation by uropathogenic Escherichia coli

      Sun, J., Marais, J. P. J., Khoo, C., LaPlante, K., Vejborg, R. M., Givskov, Michael, Tolker-Nielsen, Tim, Seeram, N. P. & Rowley, D. C., Aug 2015, In: Journal of Functional Foods. 17, p. 235-242 8 p.

      Research output: Contribution to journalLetterResearchpeer-review

    23. Published

      Computer-aided identification of recognized drugs as Pseudomonas aeruginosa quorum-sensing inhibitors

      Yang, L., Rybtke, Morten Levin, Jakobsen, Tim Holm, Hentzer, M., Bjarnsholt, Thomas, Givskov, Michael & Tolker-Nielsen, Tim, 2009, In: Antimicrobial Agents and Chemotherapy. 53, 6, p. 2432-43 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Comparative systems biology analysis to study the mode of action of the isothiocyanate compound Iberin on Pseudomonas aeruginosa

      Tan, S. Y., Liu, Y., Chua, S. L., Vejborg, R. M., Jakobsen, Tim Holm, Chew, S. C., Li, Y., Nielsen, T. E., Tolker-Nielsen, Tim, Yang, L. & Givskov, Michael, Nov 2014, In: Antimicrobial Agents and Chemotherapy. 58, 11, p. 6648-59 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Colony morphology and transcriptome profiling of Pseudomonas putida KT2440 and its mutants deficient in alginate or all EPS synthesis under controlled matric potentials

      Gulez, G., Altintas, A., Fazli, M., Dechesne, A., Workman, C., Tolker-Nielsen, Tim & Smets, B. F., 2014, In: MicrobiologyOpen. 3, 4, p. 457-469

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 8656938